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Stepwise Conformational Stabilization of a HIV-1 Clade C Consensus Envelope Trimer Immunogen Impacts the Profile of Vaccine-Induced Antibody Responses.
Alexandra Hauser, George Carnell, Kathrin Held, Guidenn Sulbaran, Nadine Tischbierek, Lisa Rogers, Georgios Pollakis, Paul Tonks, Michael Hoelscher, Song Ding, Rogier W Sanders, Christof Geldmacher, Quentin Sattentau, Winfried Weissenhorn, Jonathan L Heeney, David Peterhoff, Ralf Wagner
Sep 27, 2021
Stabilization of the HIV-1 Envelope glycoprotein trimer (Env) in its native pre-fusion closed conformation is regarded as one of several requirements for the induction of neutralizing antibody (nAb) responses, which, in turn...
Stepwise Conformational Stabilization of a HIV-1 Clade C Consensus Envelope Trimer Immunogen Impacts the Profile of Vaccine-Induced Antibody Responses
Alexandra Hauser, George Carnell, Kathrin Held, Guidenn Sulbaran, Nadine Tischbierek, Lisa Rogers, Georgios Pollakis, Paul Tonks, Michael Hoelscher, Song Ding, Rogier W. Sanders, Christof Geldmacher, Quentin Sattentau, Winfried Weissenhorn, Jonathan L. Heeney, David Peterhoff, Ralf Wagner
Jul 28, 2021
Stabilization of the HIV-1 Envelope glycoprotein trimer (Env) in its native pre-fusion closed conformation is regarded as one of several requirements for the induction of neutralizing antibody (nAb) responses, which, in turn...