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Results: 320
A combination of computational and experimental approaches identifies DNA sequence constraints associated with target site binding specificity of the transcription factor CSL.
Rubben Torella, Jinghua Li, Eddie Kinrade, Gustavo Cerda-Moya, Ashley N Contreras, Robert Foy, Robert Stojnic, Robert C Glen, Rhett A Kovall, Boris Adryan, Sarah J Bray
Aug 22, 2014
Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation.
Lenka Skalska, Robert Stojnic, Jinghua Li, Bettina Fischer, Gustavo Cerda-Moya, Hiroshi Sakai, Shahragim Tajbakhsh, Steven Russell, Boris Adryan, Sarah J Bray
Jun 10, 2015
CBP/Nejire CSL H3K56ac Notch chromatin state Acetylation Animals Cell Cycle Proteins Chromatin DNA Intergenic DNA-Binding Proteins Drosophila Proteins Drosophila melanogaster Ecdysone Enhancer Elements Genetic Gene Expression Regulation Histone Acetyltransferases Histones Receptors Notch Repressor Proteins Transcription Factors p300-CBP Transcription Factors
Role of co-repressor genomic landscapes in shaping the Notch response.
Stephen KK Chan, Gustavo Cerda-Moya, Robert Stojnic, Kat Millen, Bettina Fischer, Silvie Fexova, Lenka Skalska, Maria Gomez-Lamarca, Zoe Pillidge, Steven Russell, Sarah J Bray
Feb 14, 2018
Repressors are frequently deployed to limit the transcriptional response to signalling pathways. For example, several co-repressors interact directly with the DNA-binding protein CSL and are proposed to keep target genes...
Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics.
Maria J Gomez-Lamarca, Julia Falo-Sanjuan, Robert Stojnic, Sohaib Abdul Rehman, Leila Muresan, Matthew L Jones, Zoe Pillidge, Gustavo Cerda-Moya, Zhenyu Yuan, Sarah Baloul, Phillippe Valenti, Kerstin Bystricky, Francois Payre, Kevin O'Holleran, Rhett Kovall, Sarah J Bray
Mar 29, 2018
A key feature of Notch signaling is that it directs immediate changes in transcription via the DNA-binding factor CSL, switching it from repression to activation. How Notch generates both a sensitive and accurate response-in the...
CSL FRAP Suppressor of Hairless assisted loading Chromatin Live imaging locus tag notch signaling nuclear dynamics single-molecule tracking Animals Cell Nucleus DNA DNA-Binding Proteins Drosophila Proteins Drosophila melanogaster Models Molecular Protein Binding Receptors Notch Signal Transduction Transcriptional Activation
Isotopic signatures of methane emissions from tropical fires, agriculture and wetlands
MOYA/ZWAMPS Team, Euan G Nisbet, Grant Allen, Rebecca E Fisher, James L France, James D Lee, David Lowry, Marcos F Andrade, Thomas J Bannan, Patrick Barker, Prudence Bateson, Stéphane J-B Bauguitte, Keith N Bower, Tim J Broderick, Francis Chibesakunda, Michelle Cain, Alice E Cozens, Michael C Daly, Anita L Ganesan, Anna E Jones, Musa Lambakasa, Mark F Lunt, Archit Mehra, Isabel Moreno, Dominika Pasternak, Paul I Palmer, Carl J Percival, Joseph R Pitt, Amber J Riddle, Matthew Rigby, Jacob T Shaw, Angharad C Stell, Adam R Vaughan, Nicola J Warwick, Shona E Wilde
Dec 24, 2021
We report methane isotopologue data from aircraft and ground measurements in Africa and South America. Aircraft campaigns sampled strong methane fluxes over tropical papyrus wetlands in the Nile, Congo and Zambezi basins...
Using Causal Inference in Learning Processes to Predict Student Proficiency
The search for causal relations from observational data is an open problem that spans many fields. In the area of learning, this is especially important. The ability to determine the effect of a new teaching strategy or the...
Educational Technologies Education Learning Assessment and Measurement Computer Science and Information Technology Social Sciences and Humanities
Published by: IGI Global Scientific Publishing
Effectiveness of different accelerated partial breast irradiation techniques for the treatment of breast cancer patients
Gustavo Nader Marta, Jessica Barrett, Gustavo José Martiniano Porfirio, Ana Luiza Cabrera Martimbianco, José Luiz Barbosa Bevilacqua, Philip Poortmans, Rachel Riera
Feb 11, 2019
AIM: This systematic review was conducted to compare the effectiveness of different accelerated partial breast irradiation (APBI) techniques for the treatment of breast cancer patients. BACKGROUND: Numerous (APBI) techniques are...
Distinct Populations of Layer 5B Pyramidal Neurons in the Primary Motor Cortex
Maria V Moya
Jan 01, 0001
The ability of motor cortex to plan, execute, and refine different movements depends on the coordinated activity of many neurons found across its laminar structure. Layer 5b (L5b), a deep cortical layer that drives output...
Published by: Rockefeller University
A Patent Analysis on Big Data Projects
Studies concerning Big Data patents have been published; however, research investigating Big Data projects is scarce. Therefore, the objective of this study was to conduct an exploratory analysis of a patent database to collect...
Published by: IGI Global Scientific Publishing
Primate Amygdala Neurons Simulate Decision Processes of Social Partners.
Fabian Grabenhorst, Raymundo Báez-Mendoza, Wilfried Genest, Gustavo Deco, Wolfram Schultz
Mar 04, 2019
By observing their social partners, primates learn about reward values of objects. Here, we show that monkeys' amygdala neurons derive object values from observation and use these values to simulate a partner monkey's decision...
A note on conciseness of Engel words
It is still an open problem to determine whether the n-th Engel word [x,_n y] is concise, that is, if for every group G such that the set of values e_n(G) taken by [x,_n y] on G is finite it follows that the verbal subgroup...
A note on conciseness of Engel words
It is still an open problem to determine whether the n-th Engel word [x,_n y] is concise, that is, if for every group G such that the set of values e_n(G) taken by [x,_n y] on G is finite it follows that the verbal subgroup...
Thermal hall effect
Heat travelling down a thermal gradient has been found to undergo a significant deflection by a magnetic field in a multiferroic insulator.
Fungal G-protein-coupled receptors:
G-protein signalling pathways are involved in sensing the environment, enabling fungi to coordinate cell function, metabolism and development with their surroundings, thereby promoting their survival, propagation and virulence....
/dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology /dk/atira/pure/subjectarea/asjc/2400/2402 name=Applied Microbiology and Biotechnology /dk/atira/pure/subjectarea/asjc/1300/1311 name=Genetics /dk/atira/pure/subjectarea/asjc/2700/2726 name=Microbiology (medical) /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Fungal G-protein-coupled receptors:
G-protein signalling pathways are involved in sensing the environment, enabling fungi to coordinate cell function, metabolism and development with their surroundings, thereby promoting their survival, propagation and virulence....
/dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology /dk/atira/pure/subjectarea/asjc/2400/2402 name=Applied Microbiology and Biotechnology /dk/atira/pure/subjectarea/asjc/1300/1311 name=Genetics /dk/atira/pure/subjectarea/asjc/2700/2726 name=Microbiology (medical) /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Machine learning-selected variables associated with CD4 T cell recovery under antiretroviral therapy in very advanced HIV infection
Abstract
Background
A considerable portion of the HIV pandemic is composed of people under antiretroviral therapy, many of whom get a late diagnosis. Patients...
Dámaris P Romero-Rodríguez, Carlos Ramírez, Iván Imaz-Rosshandler, Christopher E Ormsby, Amy Peralta-Prado, Gustavo Olvera-García, Fernanda Cervantes, Daniela Würsch-Molina, Jessica Romero-Rodríguez, Wei Jiang, Gustavo Reyes-Terán, Enrique Espinosa
Apr 23, 2021
Social network community detection and hybrid optimization for dividing water supply into district metered areas
Bruno M. Brentan, Enrique Campbell, Thaisa Goulart, Daniel Manzi, Gustavo Meirelles, Manuel Herrera, Joaquin Izquierdo, Edevar Luvizotto Jr.
May 01, 2018
Water supply utilities need to properly manage their systems to guarantee a quality supply. One way to manage large systems is through division into district metered areas (DMAs). Graph clustering with an unknown number of...
Correlation Analysis of Water Demand and Predictive Variables for Short-Term Forecasting Models
Operational and economic aspects of water distribution make water demand forecasting paramount for water distribution systems (WDSs) management. However, water demand introduces high levels of uncertainty in WDS hydraulic...
Machine learning-selected variables associated with CD4 T cell recovery under antiretroviral therapy in very advanced HIV infection
Dámaris P. Romero-Rodríguez, Carlos Ramírez, Iván Imaz-Rosshandler, Christopher E. Ormsby, Amy Peralta-Prado, Gustavo Olvera-García, Fernanda Cervantes, Daniela Würsch-Molina, Jessica Romero-Rodríguez, Wei Jiang, Gustavo Reyes-Terán, Enrique Espinosa
Jun 06, 2020
Abstract: Background: A considerable portion of the HIV pandemic is composed of people under antiretroviral therapy, many of whom get a late diagnosis. Patients starting antiretroviral therapy (ART) at a very advanced stage of...
Depletion of the RNA-binding protein RBP33 results in increased expression of silenced RNA polymerase II transcripts in Trypanosoma brucei.
Design Principles of Mobile Learning Frameworks
Numerous studies show positive cognitive and affective results regarding the adoption of mobile learning; however, adoption levels are low, and when mobile learning occurs, it is not always based on innovative pedagogies. The...
Published by: IGI Global Scientific Publishing
Correlation Analysis of Water Demand and Predictive Variables for Short-Term Forecasting Models
Operational and economic aspects of water distribution make water demand forecasting paramount for water distribution systems (WDSs) management. However, water demand introduces high levels of uncertainty in WDS hydraulic...
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