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Exploration of ICT Appropriation by Disabled People and Its Effect on Self-Perceived Normalcy
Information and communication technologies (ICTs) are omnipresent and define the interactions in society. Within society, there are vulnerable groups of people for whom ICT use is more challenging. Disabled people are the most...
Published by: IGI Global Scientific Publishing
Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins.
Lysosome-related organelles (LROs) are endosomal compartments carrying tissue-specific proteins, which become enlarged in Chediak-Higashi syndrome (CHS) due to mutations in LYST. Here, we show that Drosophila Mauve, a...
Chediak-Higashi syndrome Drosophila LYST centrosomes endosomal vesicle trafficking lysosome-related organelles mauve microtubule nucleation Animals Cell Line Centrosome Chediak-Higashi Syndrome Cytoplasmic Granules Drosophila Drosophila Proteins Female Humans Lysosomes Microtubule-Associated Proteins Microtubules Mutation Oocytes Spindle Apparatus Vesicular Transport Proteins
The Lifetime Earnings Premium in the Public Sector
In a context of widespread concern about budget deficits, it is important to assess whether public sector pay is in line with the private sector. Our paper proposes an estimation of differences in lifetime values of employment...
What Lessons Can Be Learned for the Agroecological Transition From the Use of Social Media in Preventive Medicine?
In agriculture, web-based social media are increasingly used to share knowledge concerning best practices. One goal of agroecology is to reduce the use of synthetic chemical inputs. Agroecology represents a contrast with...
Published by: IGI Global Scientific Publishing
The Lifetime Earnings Premium in the Public Sector
In a context of widespread concern about budget deficits, it is important to assess whether public sector pay is in line with the private sector. Our paper proposes an estimation of differences in lifetime values of employment...
Motility and phototaxis of Gonium, the simplest differentiated colonial alga.
Green algae of the Volvocine lineage, spanning from unicellular Chlamydomonas to vastly larger Volvox, are models for the study of the evolution of multicellularity, flagellar dynamics, and developmental processes. Phototactic...
The diversity-generating benefits of a prokaryotic adaptive immune system
Stineke van Houte, Alice Ekroth, Jenny Broniewski, Hélène Chabas, Ben Ashby, Joseph Bondy-Denomy, Sylvain Gandon, Mike Boots, Angus Buckling, Edze Westra
Apr 21, 2016
Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity. This frequently results in high within-population spacer...
A computational model of the early stages of acentriolar meiotic spindle assembly.
Gaelle Letort, Isma Bennabi, Serge Dmitrieff, François Nedelec, Marie-Hélène Verlhac, Marie-Emilie Terret
Jul 30, 2020
The mitotic spindle is an ensemble of microtubules responsible for the repartition of the chromosomal content between the two daughter cells during division. In metazoans, spindle assembly is a gradual process involving dynamic...
Sleep-wake disturbances in hospitalized patients with traumatic brain injury
Catherine Duclos, Marie Dumont, Jean Paquet, Hélène Blais, Solenne Van der Maren, David K Menon, Francis Bernard, Nadia Gosselin
Nov 26, 2019
STUDY OBJECTIVES: To test whether the sleep-wake cycle disruption in patients hospitalized with traumatic brain injury (TBI) (1) is also found in patients with traumatic injuries other than TBI (non-TBI) and (2) is associated...
High-pressure synthesis and storage of solid organic compounds in active subduction zones.
Baptiste Debret, Bénédicte Ménez, Bastien Walter, Hélène Bouquerel, Pierre Bouilhol, Nadine Mattielli, Céline Pisapia, Thomas Rigaudier, Helen Myfanwy Williams
Oct 18, 2022
Recent thermodynamic and experimental studies have suggested that volatile organic compounds (e.g., methane, formate, and acetate) can be produced and stabilized in subduction zones, potentially playing an important role in the...
Micro-scale finishing of the surface and form of a Ti-6Al-4V lightweight rotor obtained by laser powder bed fusion used for air bearing
Claude Sanz, Romain Gerard, Paul Morantz, Ahmed Chérif, Paul Shore, Hélène Mainaud-Durand, Alexander J.G. Lunt
Oct 01, 2018
The European Organisation for Nuclear Research, CERN, is in the process of designing and testing parts for the next generation of linear accelerators. In order to operate the experiments, the pre-alignment precision of the...
The diversity-generating benefits of a prokaryotic adaptive immune system
Stineke van Houte, Alice Ekroth, Jenny Broniewski, Hélène Chabas, Ben Ashby, Joseph Bondy-Denomy, Sylvain Gandon, Mike Boots, Angus Buckling, Edze Westra
Apr 21, 2016
Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity. This frequently results in high within-population spacer...
An ontological foundation for ocular phenotypes and rare eye diseases.
Panagiotis I Sergouniotis, Emmanuel Maxime, Dorothée Leroux, Annie Olry, Rachel Thompson, Ana Rath, Peter N Robinson, Hélène Dollfus, ERN-EYE Ontology Study Group
Feb 15, 2019
BACKGROUND: The optical accessibility of the eye and technological advances in ophthalmic diagnostics have put ophthalmology at the forefront of data-driven medicine. The focus of this study is rare eye disorders, a group of...
A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma.
Hélène Ruffieux, Jérôme Carayol, Radu Popescu, Mary-Ellen Harper, Robert Dent, Wim HM Saris, Arne Astrup, Jörg Hager, Anthony C Davison, Armand Valsesia
Jul 06, 2020
Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large...
Parallel recovery of consciousness and sleep in acute traumatic brain injury.
Catherine Duclos, Marie Dumont, Caroline Arbour, Jean Paquet, Hélène Blais, David K Menon, Louis De Beaumont, Francis Bernard, Nadia Gosselin
Jun 21, 2018
OBJECTIVE: To investigate whether the progressive recuperation of consciousness was associated with the reconsolidation of sleep and wake states in hospitalized patients with acute traumatic brain injury (TBI). METHODS: This...
Micro-scale finishing of the surface and form of a Ti-6Al-4V lightweight rotor obtained by laser powder bed fusion used for air bearing
Claude Sanz, Romain Gerard, Paul Morantz, Ahmed Chérif, Paul Shore, Hélène Mainaud-Durand, Alexander J.G. Lunt
Oct 01, 2018
The European Organisation for Nuclear Research, CERN, is in the process of designing and testing parts for the next generation of linear accelerators. In order to operate the experiments, the pre-alignment precision of the...
EPISPOT
Hélène Ruffieux, Benjamin P Fairfax, Isar Nassiri, Elena Vigorito, Chris Wallace, Sylvia Richardson, Leonardo Bottolo
May 10, 2021
We present EPISPOT, a fully joint framework which exploits large panels of epigenetic annotations as variant-level information to enhance molecular quantitative trait locus (QTL) mapping. Thanks to a purpose-built Bayesian...
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