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Results: 113
Helicobacter pylori Eradication Therapy
Background. Though Helicobacter pylori (HP) infections have progressively declined throughout most of the industrialized countries, a gradual increase in failure of HP eradication treatments is observed. Aim. To critically...
A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages.
M Tran, S Yoon, M Teoh, S Andersen, PY Lam, BW Purdue, A Raghubar, SJ Hanson, K Devitt, K Jones, S Walters, J Monkman, A Kulasinghe, ZK Tuong, HP Soyer, IH Frazer, Q Nguyen
Aug 12, 2022
The ability to study cancer-immune cell communication across the whole tumor section without tissue dissociation is needed, especially for cancer immunotherapy development, which requires understanding of molecular mechanisms...
Labile Photo‐Induced Free Radical in α‐Ketoglutaric Acid
Adam P Gaunt, Jennifer S Lewis, Friederike Hesse, Tian Cheng, Irene Marco‐Rius, Kevin M Brindle, Arnaud Comment
Dec 15, 2021
Abstract: Hyperpolarized (HP) 13C magnetic resonance enables non‐invasive probing of metabolism in vivo. To date, only 13C‐molecules hyperpolarized with persistent trityl radicals have been injected in humans. We show here that...
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma-A Proof of Principle Study.
Stephan Ursprung, Ramona Woitek, Mary McLean, Andrew N Priest, Mireia Crispin-Ortuzar, Cara R Brodie, Andrew Gill, Marcel Gehrung, Lucian Beer, Antony CP Riddick, Johanna Field-Rayner, James T Grist, Surrin S Deen, Frank Riemer, Joshua Kaggie, Fulvio Zaccagna, Joao AG Duarte, Matthew J Locke, Amy Frary, Tevita F Aho, James N Armitage, Ruth Casey, Iosif A Mendichovszky, Sarah Welsh, Tristan Barrett, Martin Graves, Tim Eisen, Thomas J Mitchell, Anne Warren, Kevin Brindle, Evis Sala, Grant Stewart, Ferdia Gallagher
Jan 28, 2022
Differentiating aggressive clear cell renal cell carcinoma (ccRCC) from indolent lesions is challenging using conventional imaging. This work prospectively compared the metabolic imaging phenotype of renal tumors using carbon-13...
Retrospective evaluation of hyperproteinorrachia without pleocytosis (albuminocytologic dissociation) and survival in dogs.
BACKGROUND: Hyperproteinorrachia (raised cerebrospinal fluid total protein [CSF-TP]) without pleocytosis (HP) (also known as albuminocytologic dissociation) is identified in dogs with different neurologic diseases. However, the...
Atomistic Simulations of Methylammonium Lead Halide Layers on PbTiO<sub>3</sub> (001) Surfaces
Neculai Plugaru, George Alexandru Nemnes, Lucian Filip, Ioana Pintilie, Lucian Pintilie, Keith Tobias Butler, Andrei Manolescu
May 04, 2017
The substantial increase in the power conversion efficiency of hybrid perovskite solar cells, to date reaching more than 20% in the laboratory, has strongly motivated research on this class of organic-inorganic materials and...
/dk/atira/pure/subjectarea/asjc/2500/2504 name=Electronic, Optical and Magnetic Materials /dk/atira/pure/subjectarea/asjc/2100/2100 name=General Energy /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/1600/1606 name=Physical and Theoretical Chemistry
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma-A Proof of Principle Study.
Stephan Ursprung, Ramona Woitek, Mary A McLean, Andrew N Priest, Mireia Crispin-Ortuzar, Cara R Brodie, Andrew B Gill, Marcel Gehrung, Lucian Beer, Antony CP Riddick, Johanna Field-Rayner, James T Grist, Surrin S Deen, Frank Riemer, Joshua D Kaggie, Fulvio Zaccagna, Joao AG Duarte, Matthew J Locke, Amy Frary, Tevita F Aho, James N Armitage, Ruth Casey, Iosif A Mendichovszky, Sarah J Welsh, Tristan Barrett, Martin J Graves, Tim Eisen, Thomas J Mitchell, Anne Y Warren, Kevin M Brindle, Evis Sala, Grant D Stewart, Ferdia A Gallagher
Feb 20, 2022
Differentiating aggressive clear cell renal cell carcinoma (ccRCC) from indolent lesions is challenging using conventional imaging. This work prospectively compared the metabolic imaging phenotype of renal tumors using carbon-13...
First-in-human in vivo non-invasive assessment of intra-tumoral metabolic heterogeneity in renal cell carcinoma.
Maxine Tran, Arash Latifoltojar, Joana B Neves, Marianthi-Vasiliki Papoutsaki, Fiona Gong, Arnaud Comment, Ana SH Costa, Matthias Glaser, My-Anh Tran-Dang, Soha El Sheikh, Wivijin Piga, Alan Bainbridge, Anna Barnes, Tim Young, Hassan Jeraj, Ramla Awais, Sola Adeleke, Christopher Holt, James O'Callaghan, Frazer Twyman, David Atkinson, Christian Frezza, Erik Årstad, David Gadian, Mark Emberton, Shonit Punwani
Feb 22, 2019
Intratumoral genetic heterogeneity and the role of metabolic reprogramming in renal cell carcinoma (RCC) have been extensively documented. However, the distribution of these metabolic changes within the tissue has not been...
Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality.
Scott C Ritchie, Johannes Kettunen, Marta Brozynska, Artika P Nath, Aki S Havulinna, Satu Männistö, Markus Perola, Veikko Salomaa, Mika Ala-Korpela, Gad Abraham, Peter Würtz, Michael Inouye
Feb 07, 2020
BACKGROUND: GlycA is a nuclear magnetic resonance (NMR) spectroscopy biomarker that predicts risk of disease from myriad causes. It is heterogeneous; arising from five circulating glycoproteins with dynamic concentrations...
Public transport, noise complaints, and housing
Abstract: This paper investigates the effect of a new bus route on noise complaints of residents and the influence of noise on housing price. To overcome the challenge of mapping noise data with subjective emotion, we use a...
Decompositions of high-frequency Helmholtz solutions via functional calculus, and application to the finite element method
Over the last ten years, results from [48], [49], [22], and [47] decomposing high-frequency Helmholtz solutions into “low”- and “high”-frequency components have had a large impact in the numerical analysis of the Helmholtz...
Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells
Hyperpolarized 13C MRI
John Kurhanewicz, Daniel B Vigneron, Jan Henrik Ardenkjaer-Larsen, James A Bankson, Kevin Brindle, Charles H Cunningham, Ferdia A Gallagher, Kayvan R Keshari, Andreas Kjaer, Christoffer Laustsen, David A Mankoff, Matthew E Merritt, Sarah J Nelson, John M Pauly, Philips Lee, Sabrina Ronen, Damian J Tyler, Sunder S Rajan, Daniel M Spielman, Lawrence Wald, Xiaoliang Zhang, Craig R Malloy, Rahim Rizi
Dec 18, 2018
This white paper discusses prospects for advancing hyperpolarization technology to better understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13C magnetic resonance imaging's (MRI's) widespread...
Labile Photo-Induced Free Radical in α-Ketoglutaric Acid
Adam P Gaunt, Jennifer S Lewis, Friederike Hesse, Tian Cheng, Irene Marco-Rius, Kevin M Brindle, Arnaud Comment
Dec 15, 2021
Hyperpolarized (HP) 13 C magnetic resonance enables non-invasive probing of metabolism in vivo. To date, only 13 C-molecules hyperpolarized with persistent trityl radicals have been injected in humans. We show here that the free...
Atomistic Simulations of Methylammonium Lead Halide Layers on PbTiO<sub>3</sub> (001) Surfaces
Neculai Plugaru, George Alexandru Nemnes, Lucian Filip, Ioana Pintilie, Lucian Pintilie, Keith Tobias Butler, Andrei Manolescu
May 04, 2017
The substantial increase in the power conversion efficiency of hybrid perovskite solar cells, to date reaching more than 20% in the laboratory, has strongly motivated research on this class of organic-inorganic materials and...
/dk/atira/pure/subjectarea/asjc/2500/2504 name=Electronic, Optical and Magnetic Materials /dk/atira/pure/subjectarea/asjc/2100/2100 name=General Energy /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/1600/1606 name=Physical and Theoretical Chemistry
p53 activity contributes to defective interfollicular epidermal differentiation in hyperproliferative murine skin.
The expectations and realities of nutrigenomic testing in australia
Erin Tutty, Chriselle Hickerton, Bronwyn Terrill, Belinda McClaren, Rigan Tytherleigh, Elaine Stackpoole, Jaqueline Savard, Ainsley Newson, Anna Middleton, Amy Nisselle, Marie Cusack, Melissa Adamski, Clara Gaff, Sylvia Metcalfe
Apr 27, 2021
BACKGROUND: Consumer genomic testing for nutrition and wellness, (nutritional genomics), is becoming increasingly popular. Concurrently, health-care practitioners (HPs) working in private practice (including doctors interested...
The length of uninterrupted CAG repeats in stem regions of repeat disease associated hairpins determines the amount of short CAG oligonucleotides that are toxic to cells through RNA interference
Abstract Extended CAG trinucleotide repeats (TNR) in the genes huntingtin (HTT ) and androgen receptor (AR ) are the cause of two progressive...
Andrea E Murmann, Monal Patel, Si-Yeon Jeong, Elizabeth T Bartom, A Jennifer Morton, Marcus E Peter
Jan 04, 2023
Development of a virtual sensor for the comparison of heat partitions in milling under cryogenic cooling lubrication and high-pressure cutting fluid supply
Thorsten Augspurger, Matthias Koch, Thomas Lakner, Andrea De Bartolomeis, Alborz Shokrani, Thomas Bergs
Nov 30, 2021
Manufacturing high precision and high performance parts in aerospace, automotive and medical industries often requires machining of difficult-to-cut materials such as titanium, nickel and hardened alloyed steel alloys. Low...
Appetite Control across the Lifecourse
Daniel R. Crabtree, William Buosi, Claire L. Fyfe, Graham W. Horgan, Yannis Manios, Odysseas Androutsos, Angeliki Giannopoulou, Graham Finlayson, Kristine Beaulieu, Claire L. Meek, Jens J. Holst, Klaske Van Norren, Julian G. Mercer, Alexandra M. Johnstone
Dec 01, 2020
Understanding the mechanisms of hunger, satiety and how nutrients affect appetite control is important for successful weight management across the lifecourse. The primary aim of this study was to describe acute appetite control...
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