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A subset of dendritic cells induces CD4+ T cells to produce IFN-? by an IL-12-independent but CD70-dependent mechanism in vivo
Helena Soares
,
Haena Waechter
,
Nicolas Glaichenhaus
Jan 01, 0001
Interferon (IFN)-?, a cytokine critical for resistance to infection and tumors, is produced by CD4+ helper T lymphocytes after stimulation by cultured dendritic cells (DCs) that secrete a cofactor, interleukin (IL)-12. We have...
antigen presenting cell
CD4+ T lymphocyte
Cell Differentiation
dendritic cell
Leishmania major
protozoal proteins
Published by:
Rockefeller University