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Responses to global financial standards in emerging markets
This paper examines the diffusion of the Basel II Capital Accord into emerging markets (EMs). The literature on the diffusion of financial standards reinforces determinism: carefully derived standards such as those around...
Evaluation of Awareness and Usages of Simple and Processed Water Users Concerning Water Borne Diseases
The study was conducted in Shadman and Shahjamal, Lahore. The research focuses on the awareness and uses of water consumers in the area and its connection with the water-borne diarrheal diseases.
In the study, water taken from...
Published by: IJHS Medical Association
Dynamic Community And Modern Islamic Applications
Since entering the era of decline, Muslims no longer produce outstanding achievements in the field of science. Western scholars then developed science with the materials developed from the work of Muslim scholars. Of course...
Published by: Indonesia Strategic Sustainability
Matrimony and Monarchy
The research paper titled “Matrimony and Monarchy: The Failure of Bourbon-Habsburg Matrimonial Alliance,” is an in depth study of the matrimonial alliance between the Bourbon and Habsburg dynasties through the marriage of Louis...
Published by: Department of History, University of Karachi
Evaluation of Awareness and Usages of Simple and Processed Water Users Concerning Water Borne Diseases
The study was conducted in Shadman and Shahjamal, Lahore. The research focuses on the awareness and uses of water consumers in the area and its connection with the water-borne diarrheal diseases.
In the study, water taken from...
Published by: IJHS Medical Association
Politics in Balochistan
Kashif Iqbal
Dec 31, 2022
Politically, the region of Balochistan has always remained under the volatile situation. Scholars have different opinions regarding the political conditioning of Balochistan. The paper finds what type of political struggle was...
Politics Nationalism All India Muslim League Indian National Congress British policies Power-struggle History History
Published by: Department of History, University of Karachi
Testosterone Therapy in Adult-Onset Testosterone Deficiency
N Lorde, A Maarouf, RC Strange, CS König, G Hackett, A Haider, KS Haider, P Desnerck, F Saad, S Ramachandran
Oct 04, 2021
Objective: Hematocrit (HCT)/hemoglobin (Hb) ratio in (%/g/dL) is around 3, with high fidelity between measured
and derived Hb (applying the conversion using HCT) in various pathologies. We examined changes in
HCT and Hb values...
Gastrocnemius release is an effective management option for Achilles tendinopathy
PURPOSE: This systematic review aims to summarise the outcomes of gastrocnemius release in the management of Achilles Tendinopathy. METHODS: A systematic review was performed according to PRISMA guidelines. A computer-based...
Natural Products From Functional Screening of Soil Metagenomic Libraries
Hala Iqbal
Jan 01, 0001
Bacteria are a prolific source of therapeutically and industrially relevant natural products. Traditional routes of natural product discovery focus on cultured bacteria, a strategy that eludes 99% of the microbiome. ...
Published by: Rockefeller University
Intra- and inter-chromosomal interactions correlate with CTCF binding genome wide.
A prime goal in systems biology is the comprehensive use of existing high-throughput genomic datasets to gain a better understanding of chromatin organization and genome function. In this report, we use chromatin...
Expression Atlas update
Irene Papatheodorou, Pablo Moreno, Jonathan Manning, Alfonso Muñoz-Pomer Fuentes, Nancy George, Silvie Fexova, Nuno A Fonseca, Anja Füllgrabe, Matthew Green, Ni Huang, Laura Huerta, Haider Iqbal, Monica Jianu, Suhaib Mohammed, Lingyun Zhao, Andrew F Jarnuczak, Simon Jupp, John Marioni, Kerstin Meyer, Robert Petryszak, Cesar Augusto Prada Medina, Carlos Talavera-López, Sarah Teichmann, Juan Antonio Vizcaino, Alvis Brazma
Dec 19, 2019
Expression Atlas is EMBL-EBI's resource for gene and protein expression. It sources and compiles data on the abundance and localisation of RNA and proteins in various biological systems and contexts and provides open access to...
Trends, Patterns and Impact of Migration in Karachi
The process of migration has a long history. Migration occurs at international, national and regional levels. There is more trend of migration from rural to urban. Karachi (an international city of Pakistan) is a hub of...
Published by: Department of History, University of Karachi
Klinefelters Syndrome
RC Strange, CS König, A Puttanna, A Rao, G Hackett, A Haider, KS Haider, P Desnerck, F Saad, S Ramachandran
Jul 29, 2021
Background: Klinefelter’s syndrome (KS) is characterized by extra X chromosomes and features of primary hypogonadism including osteopenia and osteoporosis. Testosterone therapy (TTh) is widely used to treat men with KS and low...
The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges.
OBJECTIVE: Active surveillance (AS) has emerged as a management strategy for preventing overtreatment of indolent prostate cancer. Selection of patients for AS has traditionally proved challenging and resulted in 20-30%...
Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome.
Anila Iqbal, Marta Baldrighi, Jennifer N Murdoch, Angeleen Fleming, Christopher J Wilkinson
Oct 26, 2020
Protein aggregates are the pathogenic hallmarks of many different neurodegenerative diseases and include the accumulation of α-synuclein, the main component of Lewy bodies found in Parkinson's disease. Aggresomes are...
The Changing Paradigm of Health and Mobile Phones
This article describes how widespread adoption of mobile technology in healthcare is an innovation that is inevitable today in both developed and emerging markets around the world. Mobile health services (m-Health) act as an...
Published by: IGI Global Scientific Publishing
The role of DNA damage response in amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is a rapidly disabling and fatal neurodegenerative disease. Due to insufficient disease-modifying treatments, there is an unmet and urgent need for elucidating disease mechanisms that occur...
Inhibition of snake venom induced sterile inflammation and PLA2 activity by Titanium dioxide Nanoparticles in experimental animals.
Shubhro Chakrabartty, Md Iqbal Alam, Saumya Bhagat, Aftab Alam, Neha Dhyani, Gausal A Khan, M Sarwar Alam
Oct 29, 2020
Sterile inflammation (SI) is an essential process in response to snakebite and injury. The venom induced pathophysiological response to sterile inflammation results into many harmful and deleterious effects that ultimately leads...
Inhibition of snake venom induced sterile inflammation and PLA2 activity by Titanium dioxide Nanoparticles in experimental animals
Shubhro Chakrabartty, Md. Iqbal Alam, Saumya Bhagat, Aftab Alam, Neha Dhyani, Gausal A. Khan, M. Sarwar Alam
Jul 31, 2020
Abstract: Sterile inflammation (SI) is an essential process in response to snakebite and injury. The venom induced pathophysiological response to sterile inflammation results into many harmful and deleterious effects that...
iRhom pseudoproteases regulate ER stress-induced cell death through IP3 receptors and BCL-2.
Iqbal Dulloo, Peace Atakpa-Adaji, Yi-Chun Yeh, Clémence Levet, Sonia Muliyil, Fangfang Lu, Colin W Taylor, Matthew Freeman
Apr 11, 2022
The folding capacity of membrane and secretory proteins in the endoplasmic reticulum (ER) can be challenged by physiological and pathological perturbations, causing ER stress. If unresolved, this leads to cell death. We report a...
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