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Results: 160
miRBase
miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci from 58 species, expressing 5922 distinct mature...
MiR-221 influences effector functions and actin cytoskeleton in mast cells.
Ramon J Mayoral, Lorenzo Deho, Nicole Rusca, Nenad Bartonicek, Harpreet Kaur Saini, Anton J Enright, Silvia Monticelli
Jan 23, 2018
Mast cells have essential effector and immunoregulatory functions in IgE-associated allergic disorders and certain innate and adaptive immune responses, but the role of miRNAs in regulating mast cell functions is almost...
3T3 Cells Actin Cytoskeleton Actins Animals Base Sequence Bone Marrow Cells Cell Adhesion Cell Degranulation Cell Differentiation Cell Movement Cell Proliferation Cyclin-Dependent Kinase Inhibitor p27 Down-Regulation FIBROBLASTS Gene Knockdown Techniques Lentivirus Mast Cells Mice Mice Inbred C57BL MicroRNAs Molecular Sequence Data Oligonucleotide Array Sequence Analysis Up-Regulation
Annotation of mammalian primary microRNAs.
BACKGROUND: MicroRNAs (miRNAs) are important regulators of gene expression and have been implicated in development, differentiation and pathogenesis. Hundreds of miRNAs have been discovered in mammalian genomes. Approximately...
A Study on the Impact of the COVID-19 Pandemic on Primary, Secondary, and Tertiary Sectors of the Indian Economy
COVID-19 emerged in China in December. The World Health Organization declares this virus as Global Disaster in March. The coronavirus has affected the social, economic, political dimensions of the nations globally. In this...
Published by: IGI Global Scientific Publishing
iMotifs
MOTIVATION: Short sequence motifs are an important class of models in molecular biology, used most commonly for describing transcription factor binding site specificity patterns. High-throughput methods have been recently...
Key ingredients and recycling strategy of personal protective equipment (PPE)
Samarjeet Singh Siwal, Gauri Chaudhary, Adesh Kumar Saini, Harjot Kaur, Vipin Saini, Sudesh Kumar Mokhta, Ramesh Chand, UK Chandel, Graham Christie, Vijay Kumar Thakur
Sep 16, 2021
The COVID-19 pandemic has intensified the complications of plastic trash management and disposal. The current situation of living in fear of transmission of the COVID-19 virus has further transformed our behavioural models, such...
Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes.
Ekta Saini, Pradeep Kumar Sheokand, Vaibhav Sharma, Prakhar Agrawal, Inderjeet Kaur, Shailja Singh, Asif Mohmmed, Pawan Malhotra
Sep 20, 2021
The human malaria parasite, Plasmodium falciparum possesses unique gliding machinery referred to as the glideosome that powers its entry into the insect and vertebrate hosts. Several parasite proteins including Photosensitized...
Extracellular Lactate
James T Grist, Lorna B Jarvis, Zoya Georgieva, Sara Thompson, Harpreet Kaur Sandhu, Keith Burling, Ashley Clarke, Sarah Jackson, Mark Wills, Ferdia A Gallagher, Joanne L Jones
Feb 23, 2018
Following activation, T cells rapidly divide and acquire effector functions. This energetically demanding process depends upon the ability of T cells to undergo metabolic remodeling from oxidative phosphorylation to aerobic...
Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution.
Matthew P Davis, Claudia Carrieri, Harpreet K Saini, Stijn van Dongen, Tommaso Leonardi, Giovanni Bussotti, Jack M Monahan, Tania Auchynnikava, Angelo Bitetti, Juri Rappsilber, Robin C Allshire, Alena Shkumatava, Dónal O'Carroll, Anton J Enright
Nov 23, 2017
Spermatogenesis is associated with major and unique changes to chromosomes and chromatin. Here, we sought to understand the impact of these changes on spermatogenic transcriptomes. We show that long terminal repeats (LTRs) of...
endogenous retroviruses genome evolution lncRNA Spermatogenesis Transcriptome Animals DNA Transposable Elements Endogenous Retroviruses evolution Molecular Genomics Male Mice Open Reading Frames Promoter Regions Genetic RNA Long Noncoding Spermatocytes Spermatogenesis Terminal Repeat Sequences Transcription Genetic Transcriptome
Small non-coding RNA sequencing reveals global dysregulation of piwi-interacting RNA (piRNA) expression in gonadal malignant germ cell tumours.
Sean Laidlaw, Luz Alonso-Crisostomo, Shivani Bailey, Harpreet K Saini, Attila Molnár, James C Nicholson, Anton J Enright, Cinzia G Scarpini, Raheleh Rahbari, Nicholas Coleman, Matthew J Murray, on behalf the Children's Cancer and Leukaemia Group
Oct 26, 2022
COVID-19 Pandemic
Our study aims to analyze the change in coverage of health issues awareness, printed on the front page of Indian E-Papers (The Hindustan Times and The Times of India) for the pre-and- peri coronavirus period. The collected news...
Published by: IGI Global Scientific Publishing
The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression.
Matthew J Murray, Harpreet K Saini, Stijn van Dongen, Roger D Palmer, Balaji Muralidhar, Mark R Pett, Matias Piipari, Claire M Thornton, James C Nicholson, Anton J Enright, Nicholas Coleman
Jun 14, 2011
Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia.
Carme Camps, Harpreet K Saini, David R Mole, Hani Choudhry, Martin Reczko, José Afonso Guerra-Assunção, Ya-Min Tian, Francesca M Buffa, Adrian L Harris, Artemis G Hatzigeorgiou, Anton J Enright, Jiannis Ragoussis
Jan 23, 2018
BACKGROUND: In mammalians, HIF is a master regulator of hypoxia gene expression through direct binding to DNA, while its role in microRNA expression regulation, critical in the hypoxia response, is not elucidated genome wide....
Visualization and analysis of RNA-Seq assembly graphs.
Fahmi W Nazarie, Barbara Shih, Tim Angus, Mark W Barnett, Sz-Hau Chen, Kim M Summers, Karsten Klein, Geoffrey J Faulkner, Harpreet K Saini, Mick Watson, Stijn van Dongen, Anton J Enright, Tom C Freeman
Jan 21, 2020
RNA-Seq is a powerful transcriptome profiling technology enabling transcript discovery and quantification. Whilst most commonly used for gene-level quantification, the data can be used for the analysis of transcript isoforms....
Extracellular vesicles are independent metabolic units with asparaginase activity.
Colonial Encounters
Harjeet Kaur Badwall
Jan 07, 2015
This article examines the ways in which racialized social workers negotiate the values and practices of a social work profession that is constituted through scripts of whiteness. In particular, I examine how social work imagines...
Published by: Memorial University of Newfoundland
Modelling Urbanization, Economic Growth, and Ecological Footprint Using Environment Kuznets' Curve in Selected Asian Countries
This paper examines the relationship between urbanization, economic growth, and environmental quality using environmental Kuznets curve (EKC) hypothesis. The hypothesized link is tested using time-series analysis of 10 selected...
Published by: IGI Global Scientific Publishing
Colonial Encounters
Harjeet Kaur Badwall
Jan 07, 2015
This article examines the ways in which racialized social workers negotiate the values and practices of a social work profession that is constituted through scripts of whiteness. In particular, I examine how social work imagines...
Published by: Memorial University of Newfoundland
Fingerprint Presentation Attack Detection Using Transfer Learning Approach
In this busy world, biometric authentication methods are serving as fast authentication means. But with growing dependencies on these systems, attackers have tried to exploit these systems through various attacks; thus, there is...
Published by: IGI Global Scientific Publishing
Racialized Discourses
Harjeet Kaur Badwall
Feb 02, 2016
This paper is concerned with the ethics of knowledge production when conducting research on racial injustice. The discussion draws upon my doctoral research, in which I interviewed 23 racialized social workers in Toronto...
Published by: Memorial University of Newfoundland
Cultivating a Racialized Practitioner Ethic
In this article, we ask critical questions and reflect upon ethics and praxis for racialized practitioners working alongside Indigenous communities in the human services field. Acknowledging the lack of scholarship across the...
Published by: Memorial University of Newfoundland
Cultivating a Racialized Practitioner Ethic
In this article, we ask critical questions and reflect upon ethics and praxis for racialized practitioners working alongside Indigenous communities in the human services field. Acknowledging the lack of scholarship across the...
Published by: Memorial University of Newfoundland
Managing Consumer Loyalty
A growing body of academic and practitioner literature has highlighted the role of consumer experience management in maintaining long-term relationships with consumers. However, related studies are still divergent and there is...
Published by: IGI Global Scientific Publishing
Predicting Marathi News Class Using Semantic Entity-Driven Clustering Approach
Document management is a need for an era and managing documents in the regional languages is a significant and untouched area. Marathi corpus consisting of news is processed to form Group Entity document matrix Marathi (GEDMM)...
Published by: IGI Global Scientific Publishing
Roles for the E3 Ligase Itch in Immune Response Modulation
Sukhvinder Kaur Sahota
Jan 01, 0001
Cloning of the inversion breakpoints in the agouti mutant strain a has implicated the E3 ligase Itch in the spontaneous inflammation that occurs in these mice. 1 RH Anaylsis of a mice suggests that the inflammatory disease is...
Published by: Rockefeller University
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