Search
Results: 1
Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance.
Kristin N Adams, Amit Kumar Verma, Radha Gopalaswamy, Harresh Adikesavalu, Dinesh Kumar Singhal, Srikanth Tripathy, Uma Devi Ranganathan, David R Sherman, Kevin B Urdahl, Lalita Ramakrishnan, Rafael E Hernandez
Jan 28, 2019
The Mycobacterium tuberculosis lineage 4 strains CDC1551 and H37Rv develop tolerance to multiple antibiotics upon macrophage residence. To determine whether macrophage-induced tolerance is a general feature of clinical M....
Rv1258c Beijing lineage Tuberculosis antibiotic tolerance drug efflux ATP-Binding Cassette Transporters Antitubercular Agents Bacterial Proteins Drug Resistance Multiple Bacterial Humans Isoniazid Loss of Function Mutation MACROPHAGES Microbial Sensitivity Tests Mycobacterium tuberculosis Rifampin THP-1 Cells Tuberculosis Multidrug-Resistant