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Hans Kindler, Maestro, Feb. 10, 1947
Winthrop News Service
Jan 01, 0001
Hans Kindler will conduct the National Symphony Orchestra at Winthrop auditorium at 8 pm on Friday night. The orchestra is in its sixteenth season. This will be the seventh event in the artist series at Winthrop College in the...
Published by: Winthrop University
Faculty Videos of Resilience Narratives at Two Institutions
Burnout and mental health issues among residents are associated with adverse health consequences and suboptimal job performance, e.g. increased medical error. Given role models as key to cultivating resilience, we created...
National Symphony Orchestra, Feb. 11, 1947
Winthrop News Service
Jan 01, 0001
The National Symphony Orchestra will play tonight at 8pm at Winthrop College. Hans Kindler will direct the orchestra. The program will include selections from Mozart, Franck, Khachaturyan, and Rinsky-Korsakov.
Published by: Winthrop University
Integrative Molecular Characterization of Malignant Pleural Mesothelioma.
Malignant pleural mesothelioma (MPM) is a highly lethal cancer of the lining of the chest cavity. To expand our understanding of MPM, we conducted a comprehensive integrated genomic study, including the most detailed analysis of...
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Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis
Maria Escala-Garcia, Sander Canisius, Renske Keeman, Jonathan Beesley, Hoda Anton-Culver, Volker Arndt, Annelie Augustinsson, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Stig E. Bojesen, Manjeet K. Bolla, Hermann Brenner, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Fergus J. Couch, Kamila Czene, Mary B. Daly, Joe Dennis, Peter Devilee, Thilo Dörk, Alison M. Dunning, Douglas F. Easton, Arif B. Ekici, A. Heather Eliassen, Peter A. Fasching, Henrik Flyger, Manuela Gago-Dominguez, Montserrat García-Closas, José A. García-Sáenz, Jürgen Geisler, Graham G. Giles, Mervi Grip, Melanie Gündert, Eric Hahnen, Christopher A. Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Jaana M. Hartikainen, Bernadette A. M. Heemskerk-Gerritsen, Antoinette Hollestelle, Reiner Hoppe, John L. Hopper, David J. Hunter, William Jacot, Anna Jakubowska, Esther M. John, Audrey Y. Jung, Rudolf Kaaks, Elza Khusnutdinova, Linetta B. Koppert, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Robert N. Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Dimitrios Mavroudis, Taru A. Muranen, Heli Nevanlinna, Andrew F. Olshan, Håkan Olsson, Tjoung-Won Park-Simon, Alpa V. Patel, Paolo Peterlongo, Paul D. P. Pharoah, Kevin Punie, Paolo Radice, Gad Rennert, Hedy S. Rennert, Atocha Romero, Rebecca Roylance, Thomas Rüdiger, Matthias Ruebner, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Minouk J. Schoemaker, Christopher Scott, Melissa C. Southey, Harald Surowy, Anthony J. Swerdlow, Rulla M. Tamimi, Lauren R. Teras, Emilie Thomas, Ian Tomlinson, Melissa A. Troester, Celine M. Vachon, Qin Wang, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, Kyriaki Michailidou, Georgia Chenevix-Trench, Thomas Bachelot, Marjanka K. Schmidt
Oct 05, 2021
Abstract: Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast cancer...
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Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.
Maria Escala-Garcia, Sander Canisius, Renske Keeman, Jonathan Beesley, Hoda Anton-Culver, Volker Arndt, Annelie Augustinsson, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Marina Bermisheva, Stig E Bojesen, Manjeet K Bolla, Hermann Brenner, Federico Canzian, Jose E Castelao, Jenny Chang-Claude, Stephen J Chanock, Fergus J Couch, Kamila Czene, Mary B Daly, Joe Dennis, Peter Devilee, Thilo Dörk, Alison M Dunning, Douglas F Easton, Arif B Ekici, A Heather Eliassen, Peter A Fasching, Henrik Flyger, Manuela Gago-Dominguez, Montserrat García-Closas, José A García-Sáenz, Jürgen Geisler, Graham G Giles, Mervi Grip, Melanie Gündert, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Jaana M Hartikainen, Bernadette AM Heemskerk-Gerritsen, Antoinette Hollestelle, Reiner Hoppe, John L Hopper, David J Hunter, William Jacot, Anna Jakubowska, Esther M John, Audrey Y Jung, Rudolf Kaaks, Elza Khusnutdinova, Linetta B Koppert, Peter Kraft, Vessela N Kristensen, Allison W Kurian, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Robert N Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Dimitrios Mavroudis, Taru A Muranen, Heli Nevanlinna, Andrew F Olshan, Håkan Olsson, Tjoung-Won Park-Simon, Alpa V Patel, Paolo Peterlongo, Paul DP Pharoah, Kevin Punie, Paolo Radice, Gad Rennert, Hedy S Rennert, Atocha Romero, Rebecca Roylance, Thomas Rüdiger, Matthias Ruebner, Emmanouil Saloustros, Elinor J Sawyer, Rita K Schmutzler, Minouk J Schoemaker, Christopher Scott, Melissa C Southey, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, Lauren R Teras, Emilie Thomas, Ian Tomlinson, Melissa A Troester, Celine M Vachon, Qin Wang, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, kConFab/AOCS Investigators, Kyriaki Michailidou, Georgia Chenevix-Trench, Thomas Bachelot, Marjanka K Schmidt
Nov 25, 2021
Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast cancer progression...
Published by:
Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.
Maria Escala-Garcia, Sander Canisius, Renske Keeman, Jonathan Beesley, Hoda Anton-Culver, Volker Arndt, Annelie Augustinsson, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Marina Bermisheva, Stig E Bojesen, Manjeet K Bolla, Hermann Brenner, Federico Canzian, Jose E Castelao, Jenny Chang-Claude, Stephen J Chanock, Fergus J Couch, Kamila Czene, Mary B Daly, Joe Dennis, Peter Devilee, Thilo Dörk, Alison M Dunning, Douglas F Easton, Arif B Ekici, A Heather Eliassen, Peter A Fasching, Henrik Flyger, Manuela Gago-Dominguez, Montserrat García-Closas, José A García-Sáenz, Jürgen Geisler, Graham G Giles, Mervi Grip, Melanie Gündert, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Jaana M Hartikainen, Bernadette A M Heemskerk-Gerritsen, Antoinette Hollestelle, Reiner Hoppe, John L Hopper, David J Hunter, William Jacot, Anna Jakubowska, Esther M John, Audrey Y Jung, Rudolf Kaaks, Elza Khusnutdinova, Linetta B Koppert, Peter Kraft, Vessela N Kristensen, Allison W Kurian, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Robert N Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Dimitrios Mavroudis, Taru A Muranen, Heli Nevanlinna, Andrew F Olshan, Håkan Olsson, Tjoung-Won Park-Simon, Alpa V Patel, Paolo Peterlongo, Paul D P Pharoah, Kevin Punie, Paolo Radice, Gad Rennert, Hedy S Rennert, Atocha Romero, Rebecca Roylance, Thomas Rüdiger, Matthias Ruebner, Emmanouil Saloustros, Elinor J Sawyer, Rita K Schmutzler, Minouk J Schoemaker, Christopher Scott, Melissa C Southey, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, Lauren R Teras, Emilie Thomas, Ian Tomlinson, Melissa A Troester, Celine M Vachon, Qin Wang, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, Kyriaki Michailidou, Georgia Chenevix-Trench, Thomas Bachelot, Marjanka K Schmidt
Nov 06, 2021
Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast cancer progression...
Published by: Scientific reports
Mendelian randomisation study of smoking exposure in relation to breast cancer risk.
Hanla A Park, Sonja Neumeyer, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Adinda Baten, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Sara Y Brucker, Barbara Burwinkel, Daniele Campa, Federico Canzian, Jose E Castelao, Stephen J Chanock, Georgia Chenevix-Trench, Christine L Clarke, NBCS Collaborators, Don M Conroy, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Mary B Daly, Peter Devilee, Thilo Dörk, Isabel dos-Santos-Silva, Miriam Dwek, Diana M Eccles, A Heather Eliassen, Christoph Engel, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Henrik Flyger, Lin Fritschi, Montserrat García-Closas, José A García-Sáenz, Mia M Gaudet, Graham G Giles, Gord Glendon, Mark S Goldberg, David E Goldgar, Anna González-Neira, Mervi Grip, Pascal Guénel, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Sileny Han, Elaine F Harkness, Steven N Hart, Wei He, Bernadette AM Heemskerk-Gerritsen, John L Hopper, David J Hunter, ABCTB Investigators, kConFab Investigators, Agnes Jager, Anna Jakubowska, Esther M John, Audrey Jung, Rudolf Kaaks, Pooja Middha Kapoor, Renske Keeman, Elza Khusnutdinova, Cari M Kitahara, Linetta B Koppert, Stella Koutros, Vessela N Kristensen, Allison W Kurian, James Lacey, Diether Lambrechts, Loic Le Marchand, Wing-Yee Lo, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Maria Elena Martinez, Dimitrios Mavroudis, Alfons Meindl, Usha Menon, Roger L Milne, Taru A Muranen, Heli Nevanlinna, William G Newman, Børge G Nordestgaard, Kenneth Offit, Andrew F Olshan, Håkan Olsson, Tjoung-Won Park-Simon, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Nadege Presneau, Paolo Radice, Gad Rennert, Hedy S Rennert, Atocha Romero, Emmanouil Saloustros, Elinor J Sawyer, Marjanka K Schmidt, Rita K Schmutzler, Minouk J Schoemaker, Lukas Schwentner, Christopher Scott, Mitul Shah, Xiao-Ou Shu, Jacques Simard, Ann Smeets, Melissa C Southey, John J Spinelli, Victoria Stevens, Anthony J Swerdlow, Rulla M Tamimi, William J Tapper, Jack A Taylor, Mary Beth Terry, Ian Tomlinson, Melissa A Troester, Thérèse Truong, Celine M Vachon, Elke M van Veen, Joseph Vijai, Sophia Wang, Camilla Wendt, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, Alison M Dunning, Paul DP Pharoah, Douglas F Easton, Wei Zheng, Peter Kraft, Jenny Chang-Claude
Aug 20, 2021
BACKGROUND: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies, it is still equivocal whether smoking is causally related to breast cancer risk. METHODS: We...
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Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk.
Pooja Middha Kapoor, Nasim Mavaddat, Parichoy Pal Choudhury, Amber N Wilcox, Sara Lindström, Sabine Behrens, Kyriaki Michailidou, Joe Dennis, Manjeet K Bolla, Qin Wang, Audrey Jung, Zomoroda Abu-Ful, Thomas Ahearn, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J Aronson, Paul L Auer, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, Leslie Bernstein, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Thomas Brüning, Qiuyin Cai, Daniele Campa, Federico Canzian, Angel Carracedo, Brian D Carter, Jose E Castelao, Stephen J Chanock, Nilanjan Chatterjee, Georgia Chenevix-Trench, Christine L Clarke, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, James Y Dai, H Shelton Earp, Arif B Ekici, A Heather Eliassen, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Jonine Figueroa, Lin Fritschi, Marike Gabrielson, Manuela Gago-Dominguez, Chi Gao, Susan M Gapstur, Mia M Gaudet, Graham G Giles, Anna González-Neira, Pascal Guénel, Lothar Haeberle, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Sigrid Hatse, Jane Heyworth, Bernd Holleczek, Robert N Hoover, John L Hopper, Anthony Howell, David J Hunter, ABCTB Investigators, kConFab/AOCS Investigators, Esther M John, Michael E Jones, Rudolf Kaaks, Renske Keeman, Cari M Kitahara, Yon-Dschun Ko, Stella Koutros, Allison W Kurian, Diether Lambrechts, Loic Le Marchand, Eunjung Lee, Flavio Lejbkowicz, Martha Linet, Jolanta Lissowska, Ana Llaneza, Robert J Macinnis, Maria Elena Martinez, Tabea Maurer, Catriona Mclean, Susan L Neuhausen, William G Newman, Aaron Norman, Katie M O'Brien, Andrew F Olshan, Janet E Olson, Håkan Olsson, Nick Orr, Charles M Perou, Guillermo Pita, Eric C Polley, Ross L Prentice, Gad Rennert, Hedy S Rennert, Kathryn J Ruddy, Dale P Sandler, Christobel Saunders, Minouk J Schoemaker, Ben Schöttker, Fredrick Schumacher, Christopher Scott, Rodney J Scott, Xiao-Ou Shu, Ann Smeets, Melissa C Southey, John J Spinelli, Jennifer Stone, Anthony J Swerdlow, Rulla M Tamimi, Jack A Taylor, Melissa A Troester, Celine M Vachon, Elke M van Veen, Xiaoliang Wang, Clarice R Weinberg, Caroline Weltens, Walter Willett, Stacey J Winham, Alicja Wolk, Xiaohong R Yang, Wei Zheng, Argyrios Ziogas, Alison M Dunning, Paul DP Pharoah, Marjanka K Schmidt, Peter Kraft, Douglas F Easton, Roger L Milne, Montserrat García-Closas, Jenny Chang-Claude
Apr 14, 2020
We evaluated the joint associations between a new 313-variant PRS (PRS313) and questionnaire-based breast cancer risk factors for women of European ancestry, using 72 284 cases and 80 354 controls from the Breast Cancer...
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Genetic architectures of proximal and distal colorectal cancer are partly distinct.
Jeroen R Huyghe, Tabitha A Harrison, Stephanie A Bien, Heather Hampel, Jane C Figueiredo, Stephanie L Schmit, David V Conti, Sai Chen, Conghui Qu, Yi Lin, Richard Barfield, John A Baron, Amanda J Cross, Brenda Diergaarde, David Duggan, Sophia Harlid, Liher Imaz, Hyun Min Kang, David M Levine, Vittorio Perduca, Aurora Perez-Cornago, Lori C Sakoda, Fredrick R Schumacher, Martha L Slattery, Amanda E Toland, Fränzel JB van Duijnhoven, Bethany Van Guelpen, Antonio Agudo, Demetrius Albanes, M Henar Alonso, Kristin Anderson, Coral Arnau-Collell, Volker Arndt, Barbara L Banbury, Michael C Bassik, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, Juergen Boehm, Heiner Boeing, Marie-Christine Boutron-Ruault, Hermann Brenner, Stefanie Brezina, Stephan Buch, Daniel D Buchanan, Andrea Burnett-Hartman, Bette J Caan, Peter T Campbell, Prudence R Carr, Antoni Castells, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Keith R Curtis, Albert de la Chapelle, Douglas F Easton, Dallas R English, Edith JM Feskens, Manish Gala, Steven J Gallinger, W James Gauderman, Graham G Giles, Phyllis J Goodman, William M Grady, John S Grove, Andrea Gsur, Marc J Gunter, Robert W Haile, Jochen Hampe, Michael Hoffmeister, John L Hopper, Wan-Ling Hsu, Wen-Yi Huang, Thomas J Hudson, Mazda Jenab, Mark A Jenkins, Amit D Joshi, Temitope O Keku, Charles Kooperberg, Tilman Kühn, Sébastien Küry, Loic Le Marchand, Flavio Lejbkowicz, Christopher I Li, Li Li, Wolfgang Lieb, Annika Lindblom, Noralane M Lindor, Satu Männistö, Sanford D Markowitz, Roger L Milne, Lorena Moreno, Neil Murphy, Rami Nassir, Kenneth Offit, Shuji Ogino, Salvatore Panico, Patrick S Parfrey, Rachel Pearlman, Paul DP Pharoah, Amanda I Phipps, Elizabeth A Platz, John D Potter, Ross L Prentice, Lihong Qi, Leon Raskin, Gad Rennert, Hedy S Rennert, Elio Riboli, Clemens Schafmayer, Robert E Schoen, Daniela Seminara, Mingyang Song, Yu-Ru Su, Catherine M Tangen, Stephen N Thibodeau, Duncan C Thomas, Antonia Trichopoulou, Cornelia M Ulrich, Kala Visvanathan, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Korbinian Weigl, Stephanie J Weinstein, Emily White, Alicja Wolk, Michael O Woods, Anna H Wu, Goncalo R Abecasis, Deborah A Nickerson, Peter C Scacheri, Anshul Kundaje, Graham Casey, Stephen B Gruber, Li Hsu, Victor Moreno, Richard B Hayes, Polly A Newcomb, Ulrike Peters
Mar 02, 2021
OBJECTIVE: An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and...
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CYP3A7*1C allele
Nichola Johnson, Sarah Maguire, Anna Morra, Pooja Middha Kapoor, Katarzyna Tomczyk, Michael E Jones, Minouk J Schoemaker, Clare Gilham, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Caroline Baynes, Laura E Beane Freeman, Matthias W Beckmann, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Bram Boeckx, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Daniele Campa, Federico Canzian, Jose E Castelao, Stephen J Chanock, Georgia Chenevix-Trench, Christine L Clarke, NBCS Collaborators, Don M Conroy, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Thilo Dörk, A Heather Eliassen, Christoph Engel, D Gareth Evans, Peter A Fasching, Jonine Figueroa, Giuseppe Floris, Henrik Flyger, Manuela Gago-Dominguez, Susan M Gapstur, Montserrat García-Closas, Mia M Gaudet, Graham G Giles, Mark S Goldberg, Anna González-Neira, AOCS Group, Pascal Guénel, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Patricia A Harrington, Steven N Hart, Maartje J Hooning, John L Hopper, Anthony Howell, David J Hunter, ABCTB Investigators, kConFab Investigators, Agnes Jager, Anna Jakubowska, Esther M John, Rudolf Kaaks, Renske Keeman, Elza Khusnutdinova, Cari M Kitahara, Veli-Matti Kosma, Stella Koutros, Peter Kraft, Vessela N Kristensen, Allison W Kurian, Diether Lambrechts, Loic Le Marchand, Martha Linet, Jan Lubiński, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, John WM Martens, Dimitrios Mavroudis, Rebecca Mayes, Alfons Meindl, Roger L Milne, Susan L Neuhausen, Heli Nevanlinna, William G Newman, Sune F Nielsen, Børge G Nordestgaard, Nadia Obi, Andrew F Olshan, Janet E Olson, Håkan Olsson, Ester Orban, Tjoung-Won Park-Simon, Paolo Peterlongo, Dijana Plaseska-Karanfilska, Katri Pylkäs, Gad Rennert, Hedy S Rennert, Kathryn J Ruddy, Emmanouil Saloustros, Dale P Sandler, Elinor J Sawyer, Rita K Schmutzler, Christopher Scott, Xiao-Ou Shu, Jacques Simard, Snezhana Smichkoska, Christof Sohn, Melissa C Southey, John J Spinelli, Jennifer Stone, Rulla M Tamimi, Jack A Taylor, Rob AEM Tollenaar, Ian Tomlinson, Melissa A Troester, Thérèse Truong, Celine M Vachon, Elke M van Veen, Sophia S Wang, Clarice R Weinberg, Camilla Wendt, Hans Wildiers, Robert Winqvist, Alicja Wolk, Wei Zheng, Argyrios Ziogas, Alison M Dunning, Paul DP Pharoah, Douglas F Easton, A Forbes Howie, Julian Peto, Isabel dos-Santos-Silva, Anthony J Swerdlow, Jenny Chang-Claude, Marjanka K Schmidt, Nick Orr, Olivia Fletcher
Jan 27, 2021
BACKGROUND: Epidemiological studies provide strong evidence for a role of endogenous sex hormones in the aetiology of breast cancer. The aim of this analysis was to identify genetic variants that are associated with urinary...
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Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer.
Alexi N Archambault, Yu-Ru Su, Jihyoun Jeon, Minta Thomas, Yi Lin, David V Conti, Aung Ko Win, Lori C Sakoda, Iris Lansdorp-Vogelaar, Elisabeth FP Peterse, Ann G Zauber, David Duggan, Andreana N Holowatyj, Jeroen R Huyghe, Hermann Brenner, Michelle Cotterchio, Stéphane Bézieau, Stephanie L Schmit, Christopher K Edlund, Melissa C Southey, Robert J Macinnis, Peter T Campbell, Jenny Chang-Claude, Martha L Slattery, Andrew T Chan, Amit D Joshi, Mingyang Song, Yin Cao, Michael O Woods, Emily White, Stephanie J Weinstein, Cornelia M Ulrich, Michael Hoffmeister, Stephanie A Bien, Tabitha A Harrison, Jochen Hampe, Christopher I Li, Clemens Schafmayer, Kenneth Offit, Paul D Pharoah, Victor Moreno, Annika Lindblom, Alicja Wolk, Anna H Wu, Li Li, Marc J Gunter, Andrea Gsur, Temitope O Keku, Rachel Pearlman, D Timothy Bishop, Sergi Castellví-Bel, Leticia Moreira, Pavel Vodicka, Ellen Kampman, Graham G Giles, Demetrius Albanes, John A Baron, Sonja I Berndt, Stefanie Brezina, Stephan Buch, Daniel D Buchanan, Antonia Trichopoulou, Gianluca Severi, María-Dolores Chirlaque, Maria-José Sánchez, Domenico Palli, Tilman Kühn, Neil Murphy, Amanda J Cross, Andrea N Burnett-Hartman, Stephen J Chanock, Albert de la Chapelle, Douglas F Easton, Faye Elliott, Dallas R English, Edith JM Feskens, Liesel M Fitzgerald, Phyllis J Goodman, John L Hopper, Thomas J Hudson, David J Hunter, Eric J Jacobs, Corinne E Joshu, Sébastien Küry, Sanford D Markowitz, Roger L Milne, Elizabeth A Platz, Gad Rennert, Hedy S Rennert, Fredrick R Schumacher, Robert S Sandler, Daniela Seminara, Catherine M Tangen, Stephen N Thibodeau, Amanda E Toland, Franzel JB van Duijnhoven, Kala Visvanathan, Ludmila Vodickova, John D Potter, Satu Männistö, Korbinian Weigl, Jane Figueiredo, Vicente Martín, Susanna C Larsson, Patrick S Parfrey, Wen-Yi Huang, Heinz-Josef Lenz, Jose E Castelao, Manuela Gago-Dominguez, Victor Muñoz-Garzón, Christoph Mancao, Christopher A Haiman, Lynne R Wilkens, Erin Siegel, Elizabeth Barry, Ban Younghusband, Bethany Van Guelpen, Sophia Harlid, Anne Zeleniuch-Jacquotte, Peter S Liang, Mengmeng Du, Graham Casey, Noralane M Lindor, Loic Le Marchand, Steven J Gallinger, Mark A Jenkins, Polly A Newcomb, Stephen B Gruber, Robert E Schoen, Heather Hampel, Douglas A Corley, Li Hsu, Ulrike Peters, Richard B Hayes
Dec 12, 2019
BACKGROUND & AIMS: Early-onset colorectal cancer (CRC, in persons younger than 50 years old) is increasing in incidence; yet, in the absence of a family history of CRC, this population lacks harmonized recommendations for...
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Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
Anna Morra, Maria Escala-Garcia, Jonathan Beesley, Renske Keeman, Sander Canisius, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Paul L Auer, Annelie Augustinsson, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Stig E Bojesen, Manjeet K Bolla, Hermann Brenner, Thomas Brüning, Saundra S Buys, Bette Caan, Daniele Campa, Federico Canzian, Jose E Castelao, Jenny Chang-Claude, Stephen J Chanock, Ting-Yuan David Cheng, Christine L Clarke, NBCS Collaborators, Sarah V Colonna, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Mary B Daly, Joe Dennis, Thilo Dörk, Laure Dossus, Alison M Dunning, Miriam Dwek, Diana M Eccles, Arif B Ekici, A Heather Eliassen, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, José A García-Sáenz, Graham G Giles, Mervi Grip, Pascal Guénel, Melanie Gündert, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Steven N Hart, Jaana M Hartikainen, Arndt Hartmann, Wei He, Maartje J Hooning, Reiner Hoppe, John L Hopper, Anthony Howell, David J Hunter, ABCTB Investigators, kConFab Investigators, Agnes Jager, Anna Jakubowska, Wolfgang Janni, Esther M John, Audrey Y Jung, Rudolf Kaaks, Machteld Keupers, Cari M Kitahara, Stella Koutros, Peter Kraft, Vessela N Kristensen, Allison W Kurian, James V Lacey, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Martha Linet, Robert N Luben, Jan Lubiński, Michael Lush, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, John WM Martens, Maria Elena Martinez, Dimitrios Mavroudis, Kyriaki Michailidou, Roger L Milne, Anna Marie Mulligan, Taru A Muranen, Heli Nevanlinna, William G Newman, Sune F Nielsen, Børge G Nordestgaard, Andrew F Olshan, Håkan Olsson, Nick Orr, Tjoung-Won Park-Simon, Alpa V Patel, Bernard Peissel, Paolo Peterlongo, Dijana Plaseska-Karanfilska, Karolina Prajzendanc, Ross Prentice, Nadege Presneau, Brigitte Rack, Gad Rennert, Hedy S Rennert, Valerie Rhenius, Atocha Romero, Rebecca Roylance, Matthias Ruebner, Emmanouil Saloustros, Elinor J Sawyer, Rita K Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Snezhana Smichkoska, Melissa C Southey, Jennifer Stone, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, William J Tapper, Lauren R Teras, Mary Beth Terry, Rob AEM Tollenaar, Ian Tomlinson, Melissa A Troester, Thérèse Truong, Celine M Vachon, Qin Wang, Amber N Hurson, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, Hiltrud Brauch, Montserrat García-Closas, Paul DP Pharoah, Douglas F Easton, Georgia Chenevix-Trench, Marjanka K Schmidt
Aug 20, 2021
BACKGROUND: Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of breast...
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Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Jingjing Liu, Wendy JC Prager-Van der Smissen, J Margriet Collée, Manjeet K Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Thomas U Ahearn, Kristiina Aittomäki, Christine B Ambrosone, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Norbert Arnold, Kristan J Aronson, Annelie Augustinsson, Päivi Auvinen, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Marina Bermisheva, Leslie Bernstein, Natalia V Bogdanova, Nadja Bogdanova-Markov, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Ignacio Briceno, Sara Y Brucker, Thomas Brüning, Barbara Burwinkel, Qiuyin Cai, Hui Cai, Daniele Campa, Federico Canzian, Jose E Castelao, Jenny Chang-Claude, Stephen J Chanock, Ji-Yeob Choi, Melissa Christiaens, Christine L Clarke, NBCS Collaborators, Fergus J Couch, Kamila Czene, Mary B Daly, Peter Devilee, Isabel dos-Santos-Silva, Miriam Dwek, Diana M Eccles, A Heather Eliassen, Peter A Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, Susan M Gapstur, Montserrat García-Closas, José A García-Sáenz, Mia M Gaudet, Graham G Giles, Mark S Goldberg, David E Goldgar, Pascal Guénel, Christopher A Haiman, Niclas Håkansson, Per Hall, Patricia A Harrington, Steven N Hart, Mikael Hartman, Peter Hillemanns, John L Hopper, Ming-Feng Hou, David J Hunter, Dezheng Huo, ABCTB Investigators, Hidemi Ito, Motoki Iwasaki, Milena Jakimovska, Anna Jakubowska, Esther M John, Rudolf Kaaks, Daehee Kang, Renske Keeman, Elza Khusnutdinova, Sung-Won Kim, Peter Kraft, Vessela N Kristensen, Allison W Kurian, Loic Le Marchand, Jingmei Li, Annika Lindblom, Artitaya Lophatananon, Robert N Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Shivaani Mariapun, Keitaro Matsuo, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Usha Menon, Roger L Milne, Kenneth Muir, Anna Marie Mulligan, Susan L Neuhausen, Heli Nevanlinna, Kenneth Offit, Olufunmilayo I Olopade, Janet E Olson, Håkan Olsson, Nick Orr, Sue K Park, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Rohini Rau-Murthy, Gad Rennert, Hedy S Rennert, Valerie Rhenius, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Rita K Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Christof Sohn, Melissa C Southey, John J Spinelli, Rulla M Tamimi, William J Tapper, Soo H Teo, Mary Beth Terry, Diana Torres, Thérèse Truong, Michael Untch, Celine M Vachon, Christi J van Asperen, Alicja Wolk, Taiki Yamaji, Wei Zheng, Argyrios Ziogas, Elad Ziv, Gabriela Torres-Mejía, Thilo Dörk, Anthony J Swerdlow, Ute Hamann, Marjanka K Schmidt, Alison M Dunning, Paul DP Pharoah, Douglas F Easton, Maartje J Hooning, John WM Martens, Antoinette Hollestelle
May 13, 2020
In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a prostate...
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Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
Anna Morra, Maria Escala-Garcia, Jonathan Beesley, Renske Keeman, Sander Canisius, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Paul L Auer, Annelie Augustinsson, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Stig E Bojesen, Manjeet K Bolla, Hermann Brenner, Thomas Brüning, Saundra S Buys, Bette Caan, Daniele Campa, Federico Canzian, Jose E Castelao, Jenny Chang-Claude, Stephen J Chanock, Ting-Yuan David Cheng, Christine L Clarke, Sarah V Colonna, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Mary B Daly, Joe Dennis, Thilo Dörk, Laure Dossus, Alison M Dunning, Miriam Dwek, Diana M Eccles, Arif B Ekici, A Heather Eliassen, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, José A García-Sáenz, Graham G Giles, Mervi Grip, Pascal Guénel, Melanie Gündert, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Steven N Hart, Jaana M Hartikainen, Arndt Hartmann, Wei He, Maartje J Hooning, Reiner Hoppe, John L Hopper, Anthony Howell, David J Hunter, Agnes Jager, Anna Jakubowska, Wolfgang Janni, Esther M John, Audrey Y Jung, Rudolf Kaaks, Machteld Keupers, Cari M Kitahara, Stella Koutros, Peter Kraft, Vessela N Kristensen, Allison W Kurian, James V Lacey, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Martha Linet, Robert N Luben, Jan Lubiński, Michael Lush, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, John W M Martens, Maria Elena Martinez, Dimitrios Mavroudis, Kyriaki Michailidou, Roger L Milne, Anna Marie Mulligan, Taru A Muranen, Heli Nevanlinna, William G Newman, Sune F Nielsen, Børge G Nordestgaard, Andrew F Olshan, Håkan Olsson, Nick Orr, Tjoung-Won Park-Simon, Alpa V Patel, Bernard Peissel, Paolo Peterlongo, Dijana Plaseska-Karanfilska, Karolina Prajzendanc, Ross Prentice, Nadege Presneau, Brigitte Rack, Gad Rennert, Hedy S Rennert, Valerie Rhenius, Atocha Romero, Rebecca Roylance, Matthias Ruebner, Emmanouil Saloustros, Elinor J Sawyer, Rita K Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Snezhana Smichkoska, Melissa C Southey, Jennifer Stone, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, William J Tapper, Lauren R Teras, Mary Beth Terry, Rob A E M Tollenaar, Ian Tomlinson, Melissa A Troester, Thérèse Truong, Celine M Vachon, Qin Wang, Amber N Hurson, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, Hiltrud Brauch, Montserrat García-Closas, Paul D P Pharoah, Douglas F Easton, Georgia Chenevix-Trench, Marjanka K Schmidt
Sep 19, 2021

Background

Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of...
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.
Juliette Coignard, Michael Lush, Jonathan Beesley, Tracy A O'Mara, Joe Dennis, Jonathan P Tyrer, Daniel R Barnes, Lesley McGuffog, Goska Leslie, Manjeet K Bolla, Muriel A Adank, Simona Agata, Thomas Ahearn, Kristiina Aittomäki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Norbert Arnold, Kristan J Aronson, Banu K Arun, Annelie Augustinsson, Jacopo Azzollini, Daniel Barrowdale, Caroline Baynes, Heiko Becher, Marina Bermisheva, Leslie Bernstein, Katarzyna Białkowska, Carl Blomqvist, Stig E Bojesen, Bernardo Bonanni, Ake Borg, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Saundra S Buys, Trinidad Caldés, Maria A Caligo, Daniele Campa, Brian D Carter, Jose E Castelao, Jenny Chang-Claude, Stephen J Chanock, Wendy K Chung, Kathleen BM Claes, Christine L Clarke, GEMO Study Collaborators, EMBRACE Collaborators, J Margriet Collée, Don M Conroy, Kamila Czene, Mary B Daly, Peter Devilee, Orland Diez, Yuan Chun Ding, Susan M Domchek, Thilo Dörk, Isabel dos-Santos-Silva, Alison M Dunning, Miriam Dwek, Diana M Eccles, A Heather Eliassen, Christoph Engel, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Henrik Flyger, Florentia Fostira, Eitan Friedman, Lin Fritschi, Debra Frost, Manuela Gago-Dominguez, Susan M Gapstur, Judy Garber, Vanesa Garcia-Barberan, Montserrat García-Closas, José A García-Sáenz, Mia M Gaudet, Simon A Gayther, Andrea Gehrig, Vassilios Georgoulias, Graham G Giles, Andrew K Godwin, Mark S Goldberg, David E Goldgar, Anna González-Neira, Mark H Greene, Pascal Guénel, Lothar Haeberle, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Patricia A Harrington, Steven N Hart, Wei He, Frans BL Hogervorst, Antoinette Hollestelle, John L Hopper, Darling J Horcasitas, Peter J Hulick, David J Hunter, Evgeny N Imyanitov, kConFab Investigators, HEBON Investigators, ABCTB Investigators, Agnes Jager, Anna Jakubowska, Paul A James, Uffe Birk Jensen, Esther M John, Michael E Jones, Rudolf Kaaks, Pooja Middha Kapoor, Beth Y Karlan, Renske Keeman, Elza Khusnutdinova, Johanna I Kiiski, Yon-Dschun Ko, Veli-Matti Kosma, Peter Kraft, Allison W Kurian, Yael Laitman, Diether Lambrechts, Loic Le Marchand, Jenny Lester, Fabienne Lesueur, Tricia Lindstrom, Adria Lopez-Fernández, Jennifer T Loud, Craig Luccarini, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, John WM Martens, Noura Mebirouk, Alfons Meindl, Austin Miller, Roger L Milne, Marco Montagna, Katherine L Nathanson, Susan L Neuhausen, Heli Nevanlinna, Finn C Nielsen, Katie M O'Brien, Olufunmilayo I Olopade, Janet E Olson, Håkan Olsson, Ana Osorio, Laura Ottini, Tjoung-Won Park-Simon, Michael T Parsons, Inge Sokilde Pedersen, Beth Peshkin, Paolo Peterlongo, Julian Peto, Paul DP Pharoah, Kelly-Anne Phillips, Eric C Polley, Bruce Poppe, Nadege Presneau, Miquel Angel Pujana, Kevin Punie, Paolo Radice, Johanna Rantala, Muhammad U Rashid, Gad Rennert, Hedy S Rennert, Mark Robson, Atocha Romero, Maria Rossing, Emmanouil Saloustros, Dale P Sandler, Regina Santella, Maren T Scheuner, Marjanka K Schmidt, Gunnar Schmidt, Christopher Scott, Priyanka Sharma, Penny Soucy, Melissa C Southey, John J Spinelli, Zoe Steinsnyder, Jennifer Stone, Dominique Stoppa-Lyonnet, Anthony Swerdlow, Rulla M Tamimi, William J Tapper, Jack A Taylor, Mary Beth Terry, Alex Teulé, Darcy L Thull, Marc Tischkowitz, Amanda E Toland, Diana Torres, Alison H Trainer, Thérèse Truong, Nadine Tung, Celine M Vachon, Ana Vega, Joseph Vijai, Qin Wang, Barbara Wappenschmidt, Clarice R Weinberg, Jeffrey N Weitzel, Camilla Wendt, Alicja Wolk, Siddhartha Yadav, Xiaohong R Yang, Drakoulis Yannoukakos, Wei Zheng, Argyrios Ziogas, Kristin K Zorn, Sue K Park, Mads Thomassen, Kenneth Offit, Rita K Schmutzler, Fergus J Couch, Jacques Simard, Georgia Chenevix-Trench, Douglas F Easton, Nadine Andrieu, Antonis C Antoniou
Nov 24, 2020
Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and familial factors. About 50 common variants have been shown to modify BC risk for mutation carriers. All but three, were identified in general...
Published by:
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Jingjing Liu, Wendy J. C. Prager - van der Smissen, J. Margriet Collée, Manjeet K. Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Thomas U. Ahearn, Kristiina Aittomäki, Christine B. Ambrosone, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Norbert Arnold, Kristan J. Aronson, Annelie Augustinsson, Päivi Auvinen, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Leslie Bernstein, Natalia V. Bogdanova, Nadja Bogdanova-Markov, Stig E. Bojesen, Hiltrud Brauch, Hermann Brenner, Ignacio Briceno, Sara Y. Brucker, Thomas Brüning, Barbara Burwinkel, Qiuyin Cai, Hui Cai, Daniele Campa, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Melissa Christiaens, Christine L. Clarke, Fergus J. Couch, Kamila Czene, Mary B. Daly, Peter Devilee, Isabel dos-Santos-Silva, Miriam Dwek, Diana M. Eccles, A. Heather Eliassen, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, Susan M. Gapstur, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, David E. Goldgar, Pascal Guénel, Christopher A. Haiman, Niclas Håkansson, Per Hall, Patricia A. Harrington, Steven N. Hart, Mikael Hartman, Peter Hillemanns, John L. Hopper, Ming-Feng Hou, David J. Hunter, Dezheng Huo, Hidemi Ito, Motoki Iwasaki, Milena Jakimovska, Anna Jakubowska, Esther M. John, Rudolf Kaaks, Daehee Kang, Renske Keeman, Elza Khusnutdinova, Sung-Won Kim, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, Loic Le Marchand, Jingmei Li, Annika Lindblom, Artitaya Lophatananon, Robert N. Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Shivaani Mariapun, Keitaro Matsuo, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Usha Menon, Roger L. Milne, Kenneth Muir, Anna Marie Mulligan, Susan L. Neuhausen, Heli Nevanlinna, Kenneth Offit, Olufunmilayo I. Olopade, Janet E. Olson, Håkan Olsson, Nick Orr, Sue K. Park, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Rohini Rau-Murthy, Gad Rennert, Hedy S. Rennert, Valerie Rhenius, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Rita K. Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Christof Sohn, Melissa C. Southey, John J. Spinelli, Rulla M. Tamimi, William J. Tapper, Soo H. Teo, Mary Beth Terry, Diana Torres, Thérèse Truong, Michael Untch, Celine M. Vachon, Christi J. van Asperen, Alicja Wolk, Taiki Yamaji, Wei Zheng, Argyrios Ziogas, Elad Ziv, Gabriela Torres-Mejía, Thilo Dörk, Anthony J. Swerdlow, Ute Hamann, Marjanka K. Schmidt, Alison M. Dunning, Paul D. P. Pharoah, Douglas F. Easton, Maartje J. Hooning, John W. M. Martens, Antoinette Hollestelle, Kristine K. Sahlberg, Anne-Lise Børresen-Dale, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E. Kiserud, Kristin V. Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler, Grethe I. Grenaker Alnæs, Tone F. Bathen, Elin Borgen, Britt Fritzman, Øystein Garred, Gry Aarum Geitvik, Solveig Hofvind, Anita Langerød, Ole Christian Lingjaerde, Gunhild Mari Mælandsmo, Hege G Russnes, Helle Kristine Skjerven, Therese Sørlie, Christine Clarke, Deborah Marsh, Rodney Scott, Robert Baxter, Desmond Yip, Jane Carpenter, Alison Davis, Nirmala Pathmanathan, Peter Simpson, Dinny Graham, Mythily Sachchithananthan
Jun 17, 2021
Abstract: In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a...
Published by:
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Jingjing Liu, Wendy J. C. Prager - van der Smissen, J. Margriet Collée, Manjeet K. Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Thomas U. Ahearn, Kristiina Aittomäki, Christine B. Ambrosone, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Norbert Arnold, Kristan J. Aronson, Annelie Augustinsson, Päivi Auvinen, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Leslie Bernstein, Natalia V. Bogdanova, Nadja Bogdanova-Markov, Stig E. Bojesen, Hiltrud Brauch, Hermann Brenner, Ignacio Briceno, Sara Y. Brucker, Thomas Brüning, Barbara Burwinkel, Qiuyin Cai, Hui Cai, Daniele Campa, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Melissa Christiaens, Christine L. Clarke, Fergus J. Couch, Kamila Czene, Mary B. Daly, Peter Devilee, Isabel dos-Santos-Silva, Miriam Dwek, Diana M. Eccles, A. Heather Eliassen, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, Susan M. Gapstur, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, David E. Goldgar, Pascal Guénel, Christopher A. Haiman, Niclas Håkansson, Per Hall, Patricia A. Harrington, Steven N. Hart, Mikael Hartman, Peter Hillemanns, John L. Hopper, Ming-Feng Hou, David J. Hunter, Dezheng Huo, Hidemi Ito, Motoki Iwasaki, Milena Jakimovska, Anna Jakubowska, Esther M. John, Rudolf Kaaks, Daehee Kang, Renske Keeman, Elza Khusnutdinova, Sung-Won Kim, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, Loic Le Marchand, Jingmei Li, Annika Lindblom, Artitaya Lophatananon, Robert N. Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Shivaani Mariapun, Keitaro Matsuo, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Usha Menon, Roger L. Milne, Kenneth Muir, Anna Marie Mulligan, Susan L. Neuhausen, Heli Nevanlinna, Kenneth Offit, Olufunmilayo I. Olopade, Janet E. Olson, Håkan Olsson, Nick Orr, Sue K. Park, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Rohini Rau-Murthy, Gad Rennert, Hedy S. Rennert, Valerie Rhenius, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Rita K. Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Christof Sohn, Melissa C. Southey, John J. Spinelli, Rulla M. Tamimi, William J. Tapper, Soo H. Teo, Mary Beth Terry, Diana Torres, Thérèse Truong, Michael Untch, Celine M. Vachon, Christi J. van Asperen, Alicja Wolk, Taiki Yamaji, Wei Zheng, Argyrios Ziogas, Elad Ziv, Gabriela Torres-Mejía, Thilo Dörk, Anthony J. Swerdlow, Ute Hamann, Marjanka K. Schmidt, Alison M. Dunning, Paul D. P. Pharoah, Douglas F. Easton, Maartje J. Hooning, John W. M. Martens, Antoinette Hollestelle, Kristine K. Sahlberg, Anne-Lise Børresen-Dale, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E. Kiserud, Kristin V. Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler, Grethe I. Grenaker Alnæs, Tone F. Bathen, Elin Borgen, Britt Fritzman, Øystein Garred, Gry Aarum Geitvik, Solveig Hofvind, Anita Langerød, Ole Christian Lingjaerde, Gunhild Mari Mælandsmo, Hege G Russnes, Helle Kristine Skjerven, Therese Sørlie, Christine Clarke, Deborah Marsh, Rodney Scott, Robert Baxter, Desmond Yip, Jane Carpenter, Alison Davis, Nirmala Pathmanathan, Peter Simpson, Dinny Graham, Mythily Sachchithananthan
Jun 16, 2020
Abstract: In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a...
Published by:
Breast Cancer Risk Factors and Survival by Tumor Subtype
Anna Morra, Audrey Y Jung, Sabine Behrens, Renske Keeman, Thomas U Ahearn, Hoda Anton-Culver, Volker Arndt, Annelie Augustinsson, Päivi K Auvinen, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Carl Blomqvist, Stig E Bojesen, Manjeet K Bolla, Hermann Brenner, Ignacio Briceno, Sara Y Brucker, Nicola J Camp, Daniele Campa, Federico Canzian, Jose E Castelao, Stephen J Chanock, Ji-Yeob Choi, Christine L Clarke, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Thilo Dörk, Alison M Dunning, Miriam Dwek, Douglas F Easton, Diana M Eccles, Kathleen M Egan, D Gareth Evans, Peter A Fasching, Henrik Flyger, Manuela Gago-Dominguez, Susan M Gapstur, José A García-Sáenz, Mia M Gaudet, Graham G Giles, Mervi Grip, Pascal Guénel, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Sileny N Han, Steven N Hart, Mikael Hartman, Jane S Heyworth, Reiner Hoppe, John L Hopper, David J Hunter, Hidemi Ito, Agnes Jager, Milena Jakimovska, Anna Jakubowska, Wolfgang Janni, Rudolf Kaaks, Daehee Kang, Pooja Middha Kapoor, Cari M Kitahara, Stella Koutros, Peter Kraft, Vessela N Kristensen, James V Lacey, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Annika Lindblom, Jan Lubiński, Michael Lush, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Shivaani Mariapun, Keitaro Matsuo, Dimitrios Mavroudis, Roger L Milne, Taru A Muranen, William G Newman, Dong-Young Noh, Børge G Nordestgaard, Nadia Obi, Andrew F Olshan, Håkan Olsson, Tjoung-Won Park-Simon, Christos Petridis, Paul DP Pharoah, Dijana Plaseska-Karanfilska, Nadege Presneau, Muhammad U Rashid, Gad Rennert, Hedy S Rennert, Valerie Rhenius, Atocha Romero, Emmanouil Saloustros, Elinor J Sawyer, Andreas Schneeweiss, Lukas Schwentner, Christopher Scott, Mitul Shah, Chen-Yang Shen, Xiao-Ou Shu, Melissa C Southey, Daniel O Stram, Rulla M Tamimi, William Tapper, Rob AEM Tollenaar, Ian Tomlinson, Diana Torres, Melissa A Troester, Thérèse Truong, Celine M Vachon, Qin Wang, Sophia S Wang, Justin A Williams, Robert Winqvist, Alicja Wolk, Anna H Wu, Keun-Young Yoo, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Xiaohong R Yang, A Heather Eliassen, Michelle D Holmes, Montserrat García-Closas, Soo Hwang Teo, Marjanka K Schmidt, Jenny Chang-Claude, ABCTB Investigators, NBCS Collaborators
Feb 16, 2021
BACKGROUND: It is not known whether modifiable lifestyle factors that predict survival after invasive breast cancer differ by subtype. METHODS: We analyzed data for 121,435 women diagnosed with breast cancer from 67 studies in...
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Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
Anna Morra, Maria Escala-Garcia, Jonathan Beesley, Renske Keeman, Sander Canisius, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Paul L. Auer, Annelie Augustinsson, Laura E. Beane Freeman, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Stig E. Bojesen, Manjeet K. Bolla, Hermann Brenner, Thomas Brüning, Saundra S. Buys, Bette Caan, Daniele Campa, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Ting-Yuan David Cheng, Christine L. Clarke, Sarah V. Colonna, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Joe Dennis, Thilo Dörk, Laure Dossus, Alison M. Dunning, Miriam Dwek, Diana M. Eccles, Arif B. Ekici, A. Heather Eliassen, Mikael Eriksson, D. Gareth Evans, Peter A. Fasching, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, José A. García-Sáenz, Graham G. Giles, Mervi Grip, Pascal Guénel, Melanie Gündert, Eric Hahnen, Christopher A. Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Steven N. Hart, Jaana M. Hartikainen, Arndt Hartmann, Wei He, Maartje J. Hooning, Reiner Hoppe, John L. Hopper, Anthony Howell, David J. Hunter, Agnes Jager, Anna Jakubowska, Wolfgang Janni, Esther M. John, Audrey Y. Jung, Rudolf Kaaks, Machteld Keupers, Cari M. Kitahara, Stella Koutros, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, James V. Lacey, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Martha Linet, Robert N. Luben, Jan Lubiński, Michael Lush, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, John W. M. Martens, Maria Elena Martinez, Dimitrios Mavroudis, Kyriaki Michailidou, Roger L. Milne, Anna Marie Mulligan, Taru A. Muranen, Heli Nevanlinna, William G. Newman, Sune F. Nielsen, Børge G. Nordestgaard, Andrew F. Olshan, Håkan Olsson, Nick Orr, Tjoung-Won Park-Simon, Alpa V. Patel, Bernard Peissel, Paolo Peterlongo, Dijana Plaseska-Karanfilska, Karolina Prajzendanc, Ross Prentice, Nadege Presneau, Brigitte Rack, Gad Rennert, Hedy S. Rennert, Valerie Rhenius, Atocha Romero, Rebecca Roylance, Matthias Ruebner, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Andreas Schneeweiss, Christopher Scott, Mitul Shah, Snezhana Smichkoska, Melissa C. Southey, Jennifer Stone, Harald Surowy, Anthony J. Swerdlow, Rulla M. Tamimi, William J. Tapper, Lauren R. Teras, Mary Beth Terry, Rob A. E. M. Tollenaar, Ian Tomlinson, Melissa A. Troester, Thérèse Truong, Celine M. Vachon, Qin Wang, Amber N. Hurson, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, Hiltrud Brauch, Montserrat García-Closas, Paul D. P. Pharoah, Douglas F. Easton, Georgia Chenevix-Trench, Marjanka K. Schmidt, Anne-Lise Børresen-Dale, Kristine K. Sahlberg, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E. Kiserud, Kristin V. Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler, Grethe I. Grenaker Alnæs, Christine Clarke, Deborah Marsh, Rodney Scott, Robert Baxter, Desmond Yip, Jane Carpenter, Alison Davis, Nirmala Pathmanathan, Peter Simpson, J. Dinny Graham, Mythily Sachchithananthan
Aug 18, 2021
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Two truncating variants in FANCC and breast cancer risk.
Thilo Dörk, Paolo Peterlongo, Arto Mannermaa, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas Ahearn, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Laura E Beane Freeman, Matthias W Beckmann, Alicia Beeghly-Fadiel, Sabine Behrens, Marina Bermisheva, Carl Blomqvist, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Federico Canzian, Tsun L Chan, Jenny Chang-Claude, Stephen J Chanock, Ji-Yeob Choi, Hans Christiansen, Christine L Clarke, Fergus J Couch, Kamila Czene, Mary B Daly, Isabel dos-Santos-Silva, Miriam Dwek, Diana M Eccles, Arif B Ekici, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Jonine Figueroa, Henrik Flyger, Lin Fritschi, Marike Gabrielson, Manuela Gago-Dominguez, Chi Gao, Susan M Gapstur, Montserrat García-Closas, José A García-Sáenz, Mia M Gaudet, Graham G Giles, Mark S Goldberg, David E Goldgar, Pascal Guénel, Lothar Haeberle, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Mikael Hartman, Jan Hauke, Alexander Hein, Peter Hillemanns, Frans BL Hogervorst, Maartje J Hooning, John L Hopper, Tony Howell, Dezheng Huo, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M John, Audrey Jung, Rudolf Kaaks, Daehee Kang, Pooja Middha Kapoor, Elza Khusnutdinova, Sung-Won Kim, Cari M Kitahara, Stella Koutros, Peter Kraft, Vessela N Kristensen, Ava Kwong, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Sara Lindström, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Jan Lubiński, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Elena Martinez, Keitaro Matsuo, Dimitris Mavroudis, Alfons Meindl, Usha Menon, Roger L Milne, Nur Aishah Mohd Taib, Kenneth Muir, Anna Marie Mulligan, Susan L Neuhausen, Heli Nevanlinna, Patrick Neven, William G Newman, Kenneth Offit, Olufunmilayo I Olopade, Andrew F Olshan, Janet E Olson, Håkan Olsson, Sue K Park, Tjoung-Won Park-Simon, Julian Peto, Dijana Plaseska-Karanfilska, Esther Pohl-Rescigno, Nadege Presneau, Brigitte Rack, Paolo Radice, Muhammad U Rashid, Gad Rennert, Hedy S Rennert, Atocha Romero, Matthias Ruebner, Emmanouil Saloustros, Marjanka K Schmidt, Rita K Schmutzler, Michael O Schneider, Minouk J Schoemaker, Christopher Scott, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Susan Slager, Snezhana Smichkoska, Melissa C Southey, John J Spinelli, Jennifer Stone, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, William J Tapper, Soo H Teo, Mary Beth Terry, Amanda E Toland, Rob AEM Tollenaar, Diana Torres, Gabriela Torres-Mejía, Melissa A Troester, Thérèse Truong, Shoichiro Tsugane, Michael Untch, Celine M Vachon, Ans MW van den Ouweland, Elke M van Veen, Joseph Vijai, Camilla Wendt, Alicja Wolk, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, ABCTB Investigators, NBCS Collaborators, Alison M Dunning, Paul DP Pharoah, Detlev Schindler, Peter Devilee, Douglas F Easton
Sep 09, 2019
Fanconi anemia (FA) is a genetically heterogeneous disorder with 22 disease-causing genes reported to date. In some FA genes, monoallelic mutations have been found to be associated with breast cancer risk, while the risk...
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A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.
Lang Wu, Wei Shi, Jirong Long, Xingyi Guo, Kyriaki Michailidou, Jonathan Beesley, Manjeet K Bolla, Xiao-Ou Shu, Yingchang Lu, Qiuyin Cai, Fares Al-Ejeh, Esdy Rozali, Qin Wang, Joe Dennis, Bingshan Li, Chenjie Zeng, Helian Feng, Alexander Gusev, Richard T Barfield, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J Aronson, Paul L Auer, Myrto Barrdahl, Caroline Baynes, Matthias W Beckmann, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Louise Brinton, Per Broberg, Sara Y Brucker, Barbara Burwinkel, Trinidad Caldés, Federico Canzian, Brian D Carter, J Esteban Castelao, Jenny Chang-Claude, Xiaoqing Chen, Ting-Yuan David Cheng, Hans Christiansen, Christine L Clarke, NBCS Collaborators, Margriet Collée, Sten Cornelissen, Fergus J Couch, David Cox, Angela Cox, Simon S Cross, Julie M Cunningham, Kamila Czene, Mary B Daly, Peter Devilee, Kimberly F Doheny, Thilo Dörk, Isabel dos-Santos-Silva, Martine Dumont, Miriam Dwek, Diana M Eccles, Ursula Eilber, A Heather Eliassen, Christoph Engel, Mikael Eriksson, Laura Fachal, Peter A Fasching, Jonine Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Henrik Flyger, Lin Fritschi, Marike Gabrielson, Manuela Gago-Dominguez, Susan M Gapstur, Montserrat García-Closas, Mia M Gaudet, Maya Ghoussaini, Graham G Giles, Mark S Goldberg, David E Goldgar, Anna González-Neira, Pascal Guénel, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Per Hall, Emily Hallberg, Ute Hamann, Patricia Harrington, Alexander Hein, Belynda Hicks, Peter Hillemanns, Antoinette Hollestelle, Robert N Hoover, John L Hopper, Guanmengqian Huang, Keith Humphreys, David J Hunter, Anna Jakubowska, Wolfgang Janni, Esther M John, Nichola Johnson, Kristine Jones, Michael E Jones, Audrey Jung, Rudolf Kaaks, Michael J Kerin, Elza Khusnutdinova, Veli-Matti Kosma, Vessela N Kristensen, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Sara Lindström, Jolanta Lissowska, Wing-Yee Lo, Sibylle Loibl, Jan Lubinski, Craig Luccarini, Michael P Lux, Robert J Macinnis, Tom Maishman, Ivana Maleva Kostovska, Arto Mannermaa, JoAnn E Manson, Sara Margolin, Dimitrios Mavroudis, Hanne Meijers-Heijboer, Alfons Meindl, Usha Menon, Jeffery Meyer, Anna Marie Mulligan, Susan L Neuhausen, Heli Nevanlinna, Patrick Neven, Sune F Nielsen, Børge G Nordestgaard, Olufunmilayo I Olopade, Janet E Olson, Håkan Olsson, Paolo Peterlongo, Julian Peto, Dijana Plaseska-Karanfilska, Ross Prentice, Nadege Presneau, Katri Pylkäs, Brigitte Rack, Paolo Radice, Nazneen Rahman, Gad Rennert, Hedy S Rennert, Valerie Rhenius, Atocha Romero, Jane Romm, Anja Rudolph, Emmanouil Saloustros, Dale P Sandler, Elinor J Sawyer, Marjanka K Schmidt, Rita K Schmutzler, Andreas Schneeweiss, Rodney J Scott, Christopher G Scott, Sheila Seal, Mitul Shah, Martha J Shrubsole, Ann Smeets, Melissa C Southey, John J Spinelli, Jennifer Stone, Harald Surowy, Anthony J Swerdlow, Rulla M Tamimi, William Tapper, Jack A Taylor, Mary Beth Terry, Daniel C Tessier, Abigail Thomas, Kathrin Thöne, Rob AEM Tollenaar, Diana Torres, Thérèse Truong, Michael Untch, Celine Vachon, David Van Den Berg, Daniel Vincent, Quinten Waisfisz, Clarice R Weinberg, Camilla Wendt, Alice S Whittemore, Hans Wildiers, Walter C Willett, Robert Winqvist, Alicja Wolk, Lucy Xia, Xiaohong R Yang, Argyrios Ziogas, Elad Ziv, kConFab/AOCS Investigators, Alison M Dunning, Paul DP Pharoah, Jacques Simard, Roger L Milne, Stacey L Edwards, Peter Kraft, Douglas F Easton, Georgia Chenevix-Trench, Wei Zheng
Jul 31, 2018
The breast cancer risk variants identified in genome-wide association studies explain only a small fraction of the familial relative risk, and the genes responsible for these associations remain largely unknown. To identify...
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