Search

Results: 261
What Is Next for Rubrics?
Heidi Andrade
Aug 14, 2023
Rubrics have become ubiquitous in compulsory education and common in higher education. As with any educational innovation, it is time to reflect on the current state of rubrics and how to move ahead. This chapter identifies...
Semiconductor technology in protein kinase research and drug discovery
Since the discovery of protein kinase activity in 1954, close to 600 kinases have been discovered that have crucial roles in cell physiology. In several pathological conditions, aberrant protein kinase activity leads to abnormal...
Published by:
Protein phosphorylation analysis based on proton release detection
Phosphorylation is the most important post-translational modification of proteins in eukaryotic cells and it is catalysed by enzymes called kinases. The balance between protein phosphorylation and dephosphorylation is critical...
Published by:
Consistency of Bayesian inference with Gaussian process priors in an elliptic inverse problem
M Giordano, R Nickl
Aug 20, 2020
For $\mathcal{O}$ a bounded domain in $\mathbb{R}^d$ and a given smooth function $g:\mathcal{O}\to\mathbb{R}$, we consider the statistical nonlinear inverse problem of recovering the conductivity $f>0$ in the divergence...
Published by:
Protein phosphorylation detection using dual-mode field-effect devices and nanoplasmonic sensors
Phosphorylation by kinases is an important post-translational modification of proteins. It is a critical control for the regulation of vital cellular activities, and its dysregulation is implicated in several diseases. A common...
Published by:
Protein phosphorylation detection using dual-mode field-effect devices and nanoplasmonic sensors
Phosphorylation by kinases is an important post-translational modification of proteins. It is a critical control for the regulation of vital cellular activities, and its dysregulation is implicated in several diseases. A common...
Published by:
Increased platelet adhesion and thrombus formation in a mouse model of Alzheimer's disease
Vascular dysfunctions and Alzheimer's disease show significant similarities and overlaps. Cardiovascular risk factors (hypercholesterolemia, hypertension, obesity, atherosclerosis and diabetes) increase the risk of vascular...
Published by:
Increased platelet adhesion and thrombus formation in a mouse model of Alzheimer's disease
Vascular dysfunctions and Alzheimer's disease show significant similarities and overlaps. Cardiovascular risk factors (hypercholesterolemia, hypertension, obesity, atherosclerosis and diabetes) increase the risk of vascular...
Published by:
Protein phosphorylation analysis based on proton release detection
Phosphorylation is the most important post-translational modification of proteins in eukaryotic cells and it is catalysed by enzymes called kinases. The balance between protein phosphorylation and dephosphorylation is critical...
Published by:
Plasmonic ruler on field-effect devices for kinase drug discovery applications
Protein kinases are cellular switches that mediate phosphorylation of proteins. Abnormal phosphorylation of proteins is associated with lethal diseases such as cancer. In the pharmaceutical industry, protein kinases have become...
Published by:
Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common neurodegenerative cause of dementia in the elderly. AD is accompanied by the accumulation of amyloid peptides in the brain parenchyma and in the cerebral vessels. The sporadic form...

Published by:
Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common neurodegenerative cause of dementia in the elderly. AD is accompanied by the accumulation of amyloid peptides in the brain parenchyma and in the cerebral vessels. The sporadic form...

Published by:
Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro
Revascularisation is a key step for tissue regeneration and complete organ engineering. We describe the generation of human platelet lysate gel (hPLG), an extracellular matrix preparation from human platelets able to support the...
Published by:
Semiconductor technology in protein kinase research and drug discovery
Since the discovery of protein kinase activity in 1954, close to 600 kinases have been discovered that have crucial roles in cell physiology. In several pathological conditions, aberrant protein kinase activity leads to abnormal...
Published by:
A Role for RAS in V-CRK Transformation
Heidi Greulich
Jan 01, 0001
The v-Crk oncogene product, while possessing no intrinsic tyrosine kinase activity, causes an elevation in levels of cellular phosphotyrosine as it transforms chicken embryo fibroblasts (CEF). Because of this similarity to v-Src...
Published by: Rockefeller University
“Teach Me How to Stay on Top of Things”
Heidi Zhang
Dec 12, 2021
The COVID-19 pandemic has prompted universities across the globe to shift to digital platforms. This shift has ensured the minimization of disruption by offering flexible, transparent, and accessible remote learning that aligns...
“Teach Me How to Stay on Top of Things”
Heidi Zhang
Dec 12, 2021
The COVID-19 pandemic has prompted universities across the globe to shift to digital platforms. This shift has ensured the minimization of disruption by offering flexible, transparent, and accessible remote learning that aligns...
Plasmonic ruler on field-effect devices for kinase drug discovery applications
Protein kinases are cellular switches that mediate phosphorylation of proteins. Abnormal phosphorylation of proteins is associated with lethal diseases such as cancer. In the pharmaceutical industry, protein kinases have become...
Published by:

|<

<

1

2

3

4

5

>

>|