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Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU
Christian Lanckohr, Christian Boeing, Jan J De Waele, Dylan W de Lange, Jeroen Schouten, Menno Prins, Maarten Nijsten, Pedro Povoa, Andrew Conway Morris, Hendrik Bracht
Oct 29, 2021
Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU
Christian Lanckohr, Christian Boeing, Jan J. De Waele, Dylan W. de Lange, Jeroen Schouten, Menno Prins, Maarten Nijsten, Pedro Povoa, Andrew Conway Morris, Hendrik Bracht
Nov 12, 2021
Abstract: Background: Severe infections and multidrug-resistant pathogens are common in critically ill patients. Antimicrobial stewardship (AMS) and therapeutic drug monitoring (TDM) are contemporary tools to optimize the use of...
Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU
Christian Lanckohr, Christian Boeing, Jan J De Waele, Dylan W de Lange, Jeroen Schouten, Menno Prins, Maarten Nijsten, Pedro Povoa, Andrew Conway Morris, Hendrik Bracht
Sep 26, 2021
Background
Severe infections and multidrug-resistant pathogens are common in critically ill patients. Antimicrobial stewardship (AMS) and therapeutic drug monitoring (TDM) are contemporary tools to optimize the use of...
antibiotic Critical Care Therapeutic drug monitoring Antimicrobial Stewardship Multiresistant bacteria
Published by: Annals of intensive care
Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU
Christian Lanckohr, Christian Boeing, Jan J. De Waele, Dylan W. de Lange, Jeroen Schouten, Menno Prins, Maarten Nijsten, Pedro Povoa, Andrew Conway Morris, Hendrik Bracht
Aug 26, 2021
Abstract: Background: Severe infections and multidrug-resistant pathogens are common in critically ill patients. Antimicrobial stewardship (AMS) and therapeutic drug monitoring (TDM) are contemporary tools to optimize the use of...
Self-similar relativistic blast waves with energy injection
Hendrik Van Eerten
Aug 21, 2014
A sufficiently powerful astrophysical source with power-law luminosity in time will give rise to a self-similar relativistic blast wave with a reverse shock travelling into the ejecta and a forward shock moving into the...
Extensive ground state entropy in supersymmetric lattice models
Hendrik Van Eerten
Dec 01, 2005
We present the result of calculations of the Witten index for a supersymmetric lattice model on lattices of various type and size. Because the model remains supersymmetric at finite lattice size, the Witten index can be...
Gamma-ray burst afterglow plateau break time-luminosity correlations favour thick shell models over thin shell models
Hendrik J. van Eerten
Dec 11, 2014
A number of correlations between observables have been found to exist for gamma-ray burst (GRB) afterglows, linking ejecta energy to prompt and afterglow energy release and linking early stage optical and X-ray luminosity to the...
Gamma
In recent years, dynamical relativistic jet simulation techniques have progressed to a point where it is becoming possible to fully numerically resolve gamma-ray burst (GRB) blast-wave evolution across scales. However, the...
Gamma-Ray Burst Afterglow Scaling Relations for the Full Blast Wave Evolution
We demonstrate that gamma-ray burst afterglow spectra and light curves can be calculated for arbitrary explosion and radiation parameters by scaling the peak flux and the critical frequencies connecting different spectral...
Glucose oxidase directly immobilized onto highly porous gold electrodes for sensing and fuel cell applications
The successful implementation of redox-enzyme electrodes in biosensors and enzymatic biofuel cells has been the subject of extensive research.
For high sensitivity and high energy-conversion efficiency, the effective...
For high sensitivity and high energy-conversion efficiency, the effective...
The Effect of Social Support Features via Buddies in App-Based Habit Building
App-based habit building has been shown to be a good tool for forming desired habits; however, it is unclear how much individual features that are present in many apps contribute to the success of habit building. In this paper...
Published by: IGI Global Scientific Publishing
Basic residues R260 and K357 affect the conformational dynamics of the major facilitator superfamily multidrug transporter LmrP.
Secondary-active multidrug transporters can confer resistance on cells to pharmaceuticals by mediating their extrusion away from intracellular targets via substrate/H(+)(Na(+)) antiport. While the interactions of catalytic...
Arginine Bacterial Proteins Benzalkonium Compounds Benzimidazoles Binding Sites Biological Transport Cell Membrane Cross-Linking Reagents Cysteine Drug Resistance Multiple Ethidium Hydrogen-Ion Concentration Immunoblotting Lactococcus lactis Lysine Membrane Transport Proteins Mutagenesis Site-Directed Mutation Protein Conformation Proton-Motive Force Protons
A priori bounds for rough differential equations with a non-linear damping term
We consider a rough differential equation with a non-linear damping drift term: dY(t)=−|Y|m−1Y(t)dt+σ(Y(t))dX(t), where X is a branched rough path of arbitrary regularity α>0, m>1 and where σ is smooth and satisfies an m...
Gamma-Ray Burst Afterglow Scaling Relations for the Full Blast Wave Evolution
We demonstrate that gamma-ray burst afterglow spectra and light curves can be calculated for arbitrary explosion and radiation parameters by scaling the peak flux and the critical frequencies connecting different spectral...
Gamma-ray burst afterglow light curves from a Lorentz-boosted simulation frame and the shape of the jet break
The early stages of decelerating gamma-ray burst (GRB) afterglow jets have been notoriously difficult to resolve numerically using two-dimensional hydrodynamical simulations even at very high resolution, due to the extreme...
Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients
Alexis Tabah, Niccolò Buetti, Quentin Staiquly, Stéphane Ruckly, Murat Akova, Abdullah Tarik Aslan, Marc Leone, Andrew Conway Morris, Matteo Bassetti, Kostoula Arvaniti, Jeffrey Lipman, Ricard Ferrer, Haibo Qiu, José-Artur Paiva, Pedro Povoa, Liesbet De Bus, Jan De Waele, Farid Zand, Mohan Gurjar, Adel Alsisi, Khalid Abidi, Hendrik Bracht, Yoshiro Hayashi, Kyeongman Jeon, Muhammed Elhadi, François Barbier, Jean-François Timsit
Mar 14, 2023
antibiotic resistance Bacteremia Bloodstream Infection Hospital-acquired Humans Escherichia coli Bacteremia Cross Infection Carbapenems Anti-Infective Agents Anti-Bacterial Agents Cohort Studies Prospective Studies Adult Intensive Care Units Hospitals
Published by: Intensive care medicine
Electrodeposited highly porous gold microelectrodes for the direct electrocatalytic oxidation of aqueous glucose
High-surface area electrode materials are particularly relevant for a vast range of applications, especially in the field of catalysis and electrochemical energy conversion (e.g. fuel cells).
In this work high surface...
In this work high surface...
Gamma-ray burst afterglow plateau break time-luminosity correlations favour thick shell models over thin shell models
Hendrik J. van Eerten
Dec 11, 2014
A number of correlations between observables have been found to exist for gamma-ray burst (GRB) afterglows, linking ejecta energy to prompt and afterglow energy release and linking early stage optical and X-ray luminosity to the...
Local bounds for stochastic reaction diffusion equations
We prove a priori bounds for solutions of stochastic reaction diffusion equations with super-linear damping in the reaction term. These bounds provide a control on the supremum of solutions on any compact space-time set which...
Gamma
In recent years, dynamical relativistic jet simulation techniques have progressed to a point where it is becoming possible to fully numerically resolve gamma-ray burst (GRB) blast-wave evolution across scales. However, the...
Extensive ground state entropy in supersymmetric lattice models
Hendrik Van Eerten
Dec 01, 2005
We present the result of calculations of the Witten index for a supersymmetric lattice model on lattices of various type and size. Because the model remains supersymmetric at finite lattice size, the Witten index can be...
Self-similar relativistic blast waves with energy injection
Hendrik Van Eerten
Aug 21, 2014
A sufficiently powerful astrophysical source with power-law luminosity in time will give rise to a self-similar relativistic blast wave with a reverse shock travelling into the ejecta and a forward shock moving into the...
Gamma-ray burst afterglow light curves from a Lorentz-boosted simulation frame and the shape of the jet break
The early stages of decelerating gamma-ray burst (GRB) afterglow jets have been notoriously difficult to resolve numerically using two-dimensional hydrodynamical simulations even at very high resolution, due to the extreme...
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