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Neurobehavioural sequelae of social deprivation in rodents revisited
TW Robbins
Apr 11, 2018
The significance of investigating effects of deprivation of social experience in rodents is reviewed in the context of the review by Robbins et al. (1996) in the Journal of Psychopharmacology (10: 39-47). The early development...
ADHD Social Isolation animal model Cognition Dopamine Hippocampus hyperactivity Prefrontal Cortex prepulse inhibition Schizophrenia Serotonin Striatum Animals Attention Deficit Disorder with Hyperactivity Behavior Animal Cognition Dopamine Hippocampus Humans Mental Disorders motivation Rodentia Schizophrenia Serotonin Social Isolation
Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom
Hilary A. Robbins, Karine Alcala, Anthony J. Swerdlow, Minouk J. Schoemaker, Nick Wareham, Ruth C. Travis, Philip A. J. Crosbie, Matthew Callister, David R. Baldwin, Rebecca Landy, Mattias Johansson
Aug 02, 2021
Abstract: Background: The National Health Service England (NHS) classifies individuals as eligible for lung cancer screening using two risk prediction models, PLCOm2012 and Liverpool Lung Project-v2 (LLPv2). However, no study...
A comparison of various aggregation functions in multi-criteria decision analysis for drug benefit-risk assessment.
Multi-criteria decision analysis is a quantitative approach to the drug benefit-risk assessment which allows for consistent comparisons by summarising all benefits and risks in a single score. The multi-criteria decision...
Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom.
Hilary A Robbins, Karine Alcala, Anthony J Swerdlow, Minouk J Schoemaker, Nick Wareham, Ruth C Travis, Philip AJ Crosbie, Matthew Callister, David R Baldwin, Rebecca Landy, Mattias Johansson
May 03, 2021
BACKGROUND: The National Health Service England (NHS) classifies individuals as eligible for lung cancer screening using two risk prediction models, PLCOm2012 and Liverpool Lung Project-v2 (LLPv2). However, no study has compared...
Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom
Hilary A. Robbins, Karine Alcala, Anthony J. Swerdlow, Minouk J. Schoemaker, Nick Wareham, Ruth C. Travis, Philip A. J. Crosbie, Matthew Callister, David R. Baldwin, Rebecca Landy, Mattias Johansson
Jun 08, 2021
Abstract: Background: The National Health Service England (NHS) classifies individuals as eligible for lung cancer screening using two risk prediction models, PLCOm2012 and Liverpool Lung Project-v2 (LLPv2). However, no study...
Population-Based Precision Cancer Screening
Pamela M Marcus, Nora Pashayan, Timothy R Church, V Paul Doria-Rose, Michael K Gould, Rebecca A Hubbard, Michael Marrone, Diana L Miglioretti, Paul D Pharoah, Paul F Pinsky, Katherine A Rendle, Hilary A Robbins, Megan C Roberts, Betsy Rolland, Mark Schiffman, Jasmin A Tiro, Ann G Zauber, Deborah M Winn, Muin J Khoury
Sep 29, 2016
Duke Energy Sustainability Director Tapped for MBA Lecture
Winthrop University
Jan 01, 0001
The lecture will be April 1 at 7 p.m. in Whitton Auditorium. The featured speaker is Hilary Davidson, sustainbility director for Duke Energy.
Published by: Winthrop University
Capabilities, resources, learning and innovation
The dominant approach in economics, often referred to as neoclassical economics, gradually acquired its leading status in the years following the publication of Lionel Robbins’s (1932) famous essay on the nature and significance...
Using and managing multiple passwords
Security policies are required that protect information from unauthorised access, and also respect challenges users face in creating, and particularly managing, increasing numbers of passwords. This paper investigates real...
The impact of a needs‐based model of care on accessibility and quality of care within children's mental health services
Abstract: Background: The i‐THRIVE Programme is a needs‐based model of care, based on the THRIVE Framework, that is being implemented across the United Kingdom with the aim of improving outcomes for children and young people's...
Using and managing multiple passwords
Security policies are required that protect information from unauthorised access, and also respect challenges users face in creating, and particularly managing, increasing numbers of passwords. This paper investigates real...
Fossils Collected This Summer Will Be Subject of Tests
Winthrop University
Jan 01, 0001
Boyer and two environmental science majors, Tim Swartz and Ty Robbins, took a 13-day trip in June to Utah and Nevada to collect rock samples on federal lands believed to have been the site of mass extinctions. The Winthrop study...
Published by: Winthrop University
Set-shifting-related basal ganglia deformation as a novel familial marker of obsessive-compulsive disorder.
Masanori Isobe, Matilde Vaghi, Naomi A Fineberg, Annemieke M Apergis-Schoute, Edward T Bullmore, Barbara J Sahakian, Trevor W Robbins, Samuel R Chamberlain
Mar 17, 2021
The symptoms of obsessive-compulsive disorder (OCD) are suggestive of cognitive rigidity, and previous work identified impaired flexible responding on set-shifting tasks in such patients. The basal ganglia are central to habit...
Pilot study to establish a prospective neonatal cohort
BACKGROUND: Genetic risk variants and preterm birth are early and potent risk factors for later neuropsychiatric disorders. To understand the interrelationships between these factors, a large-scale genetic study of very preterm...
The Ursinus Weekly, October 30, 1911
Notice to Weekly subscribers Scrub game called off Scrub wins from Royersford High Saturday, 16-0 Dickinson cancelled: Game called off because of Dickinson's uncalled for protest of Gay Lehigh wins Halloween programs ...
Ursinus College Collegeville Pennsylvania newspaper Football George Gay YMCA YWCA Zwinglian literary society Schaff literary society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Are candidate neurocognitive endophenotypes of OCD present in paediatric patients? A systematic review.
Aleya A Marzuki, Ana Maria Frota Lisboa Pereira de Souza, Barbara J Sahakian, Trevor W Robbins
May 01, 2020
To-date it has been difficult to ascertain the exact cognitive profile of childhood OCD as studies report variable results. Adult OCD research lately utilises the endophenotype approach; studying cognitive traits that are...
Regional cerebral blood flow single photon emission computed tomography for detection of Frontotemporal dementia in people with suspected dementia.
Hilary A Archer, Nadja Smailagic, Christeena John, Robin B Holmes, Yemisi Takwoingi, Elizabeth J Coulthard, Sarah Cullum
Oct 10, 2018
BACKGROUND: In the UK, dementia affects 5% of the population aged over 65 years and 25% of those over 85 years. Frontotemporal dementia (FTD) represents one subtype and is thought to account for up to 16% of all degenerative...
Effective Use of Animal Models for Therapeutic Development in Psychiatric and Substance Use Disorders.
Athina Markou and others argue forcefully for the adoption of a "translational-back translational strategy" for central nervous system drug discovery involving novel application of drugs with established safety profiles in...
Animal models atomoxetine Drug Discovery Ketamine Review Varenicline Adrenergic Uptake Inhibitors Animals Antidepressive Agents Atomoxetine Hydrochloride Attention Deficit Disorder with Hyperactivity Depressive Disorder Drug Discovery Humans Ketamine Mental Disorders Models Animal Nicotinic Agonists Tobacco Use Disorder Varenicline
The impact of a needs-based model of care on accessibility and quality of care within children's mental health services
BACKGROUND: The i-THRIVE Programme is a needs-based model of care, based on the THRIVE Framework, that is being implemented across the United Kingdom with the aim of improving outcomes for children and young people's mental...
Computational modelling reveals contrasting effects on reinforcement learning and cognitive flexibility in stimulant use disorder and obsessive-compulsive disorder
Jonathan W. Kanen, Karen D. Ersche, Naomi A. Fineberg, Trevor W. Robbins, Rudolf N. Cardinal
Jul 19, 2020
Abstract: Rationale: Disorders of compulsivity such as stimulant use disorder (SUD) and obsessive-compulsive disorder (OCD) are characterised by deficits in behavioural flexibility, some of which have been captured using...
Cognitive behavior therapy for comorbid Obsessive-Compulsive Disorder in high functioning Autism Spectrum Disorders
Ailsa J Russell, Amita Jassi, Miquel A Fullana, Hilary Mack, Kate Johnston, Isobel Heyman, Declan G Murphy, David Mataix-Cols
Aug 01, 2013
Background: High rates of anxiety disorders, particularly Obsessive Compulsive Disorder (OCD) are reported in people with Autism Spectrum Disorders (ASD). Group cognitive behavioural (CBT) treatment has been found effective for...
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