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Integrated genomics point to immune vulnerabilities in pleural mesothelioma
Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris-Rosendahl, Yu Zhi Zhang, Xiao-Ming Sun, Spyridon Gennatas, Robert C. Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G. Nicholson, Sanjay Popat, Anne E. Willis, Marion MacFarlane, Mark Lathrop, Anne M. Bowcock, Miriam F. Moffatt, William O. C. M. Cookson
Sep 27, 2021
Integrated genomics point to immune vulnerabilities in pleural mesothelioma.
Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris-Rosendahl, Yu Zhi Zhang, Xiao-Ming Sun, Spyridon Gennatas, Robert Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G Nicholson, Sanjay Popat, Anne Willis, Marion MacFarlane, Mark Lathrop, Anne M Bowcock, Miriam F Moffatt, William OCM Cookson
Nov 25, 2021
Pleural mesothelioma is an aggressive malignancy with limited effective therapies. In order to identify therapeutic targets, we integrated SNP genotyping, sequencing and transcriptomics from tumours and low-passage...
Integrated genomics point to immune vulnerabilities in pleural mesothelioma.
Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris-Rosendahl, Yu Zhi Zhang, Xiao-Ming Sun, Spyridon Gennatas, Robert C Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G Nicholson, Sanjay Popat, Anne E Willis, Marion MacFarlane, Mark Lathrop, Anne M Bowcock, Miriam F Moffatt, William O C M Cookson
Oct 29, 2021
Published by: Scientific reports
Integrated genomics point to immune vulnerabilities in pleural mesothelioma.
Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris-Rosendahl, Yu Zhi Zhang, Xiao-Ming Sun, Spyridon Gennatas, Robert C Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G Nicholson, Sanjay Popat, Anne E Willis, Marion MacFarlane, Mark Lathrop, Anne M Bowcock, Miriam F Moffatt, William OCM Cookson
Mar 21, 2022
Aged Aged 80 and over Antineoplastic Agents Biomarkers Tumor Biopsy DNA Copy Number Variations Female Gene Expression Profiling Gene Expression Regulation Neoplastic Genomics Hippo Signaling Pathway Humans Male Mesothelioma Malignant Middle Aged Mutation Pleura Pleural Neoplasms Primary Cell Culture whole genome sequencing