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Results: 31
Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations.
Yali Xue, Massimo Mezzavilla, Marc Haber, Shane McCarthy, Yuan Chen, Vagheesh Narasimhan, Arthur Gilly, Qasim Ayub, Vincenza Colonna, Lorraine Southam, Christopher Finan, Andrea Massaia, Himanshu Chheda, Priit Palta, Graham Ritchie, Jennifer Asimit, George Dedoussis, Paolo Gasparini, Aarno Palotie, Samuli Ripatti, Nicole Soranzo, Daniela Toniolo, James F Wilson, Richard Durbin, Chris Tyler-Smith, Eleftheria Zeggini
Aug 15, 2018
The genetic features of isolated populations can boost power in complex-trait association studies, and an in-depth understanding of how their genetic variation has been shaped by their demographic history can help leverage these...
Estimating Morphological Features of Plant Growth Using Machine Vision
Motivated by the fact that human visionary intelligence plays a vital role in guiding many of the agriculture practices, this article represents an effective use of machine vision technology for estimating plant morphological...
Published by: IGI Global Scientific Publishing
Analyzing Dependence of Key Macroeconomic Variables on BSE Using Regression
This paper aims to analyze the dependence of key macroeconomic variables on Bombay Stock Exchange (BSE) Sensex using regression modelling technique in RStudio. Monthly data points spanning a period from 2012 to 2019 has been...
Published by: IGI Global Scientific Publishing
Trends in COVID-19 Publications
Background: Research publications related to the novel coronavirus disease COVID-19 are rapidly increasing. However, current online literature hubs, even with artificial intelligence, are limited in identifying the complexity of...
Segmenting Reviewers Based on Reviewer and Review Characteristics
Being experiential commodities, it becomes difficult to make any judgment about hotels or attractions before their utilization. This is where the reviews provided by guests/tourists play an influential role. Therefore, it...
Published by: IGI Global Scientific Publishing
Tailoring Interleaflet Lipid Transfer with a DNA-based Synthetic Enzyme.
Lipid membranes, enveloping all living systems, are of crucial importance, and control over their structure and composition is a highly desirable functionality of artificial structures. However, the rational design of...
SDN-Based Traffic Monitoring in Data Center Network Using Floodlight Controller
Data center networks are the backbone of IT infrastructure and cloud services. According to traffic pattern research, a small group of flows transport the vast majority of the bytes and are referred to as elephant flows. Proper...
Published by: IGI Global Scientific Publishing
Scalable Recommendation Using Large Scale Graph Partitioning With Pregel and Giraph
Social Big Data is generated by interactions of connected users on social network. Sharing of opinions and contents amongst users, reviews of users for products, result in social Big Data. If any user intends to select products...
Published by: IGI Global Scientific Publishing
Role of the Secondary Phase η During High-Temperature Compression of ATI 718Plus®
Abstract: High-temperature compression tests were performed on a Ni-base superalloy with a multi-phase microstructure. Particular attention was given on the influence of the η phase on recrystallization of ATI 718Plus®. The...
Role of the Secondary Phase η During High-Temperature Compression of ATI 718Plus®
Abstract: High-temperature compression tests were performed on a Ni-base superalloy with a multi-phase microstructure. Particular attention was given on the influence of the η phase on recrystallization of ATI 718Plus®. The...
Hydrogen Adsorption in Metal-Organic Framework MIL-101(Cr) - Adsorbate Densities and Enthalpies from Sorption, Neutron Scattering, <i>in Situ</i> X-ray Diffraction, Calorimetry, and Molecular Simulations
Nuno Bimbo, Kang Zhang, Himanshu Aggarwal, Timothy J. Mays, Jianwen Jiang, Leonard J. Barbour, Valeska P. Ting
Aug 23, 2021
In this paper, hydrogen adsorption in metal-organic framework MIL-101(Cr) is investigated through a combination of sorption experiments, modeling of experimental isotherms, differential scanning calorimetry (DSC), neutron...
adsorbed density enthalpies of adsorption Hydrogen storage inelastic neutron scattering metal-organic frameworks MIL-101(Cr) /dk/atira/pure/subjectarea/asjc/1500/1501 name=Chemical Engineering (miscellaneous) /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1603 name=Electrochemistry /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry
Inventory Replenishment Policies for Two Successive Generations of Technology Products Under Permissible Delay in Payments
In this age of digitalization, when every industry is undergoing technological disruption, there is a big role of digital gadgets and technology products. A key feature of these digital gadgets is the short length of the product...
Published by: IGI Global Scientific Publishing
Application of Machine Learning Models for Malware Classification With Real and Synthetic Datasets
Stacking of multiple Machine Learning (ML) classifiers have gained popularity in addressing anomalous data classification along with Deep Learning (DL) algorithms. This study compares traditional ML classifiers, multi-layer...
Published by: IGI Global Scientific Publishing
Cations Regulate Membrane Attachment and Functionality of DNA Nanostructures.
Diana Morzy, Roger Rubio-Sánchez, Himanshu Joshi, Aleksei Aksimentiev, Lorenzo Di Michele, Ulrich F Keyser
Jun 07, 2021
The interplay between nucleic acids and lipids underpins several key processes in molecular biology, synthetic biotechnology, vaccine technology, and nanomedicine. These interactions are often electrostatic in nature, and much...
Published by: Journal of the American Chemical Society
Adoption and Usage of Over-the-Top Entertainment Services
Over-the-top (OTT) is the name of media entertainment services delivered over the internet, bypassing traditional mediums. The consumer preference for OTT entertainment platforms is increasing at a fast rate and is showing...
Published by: IGI Global Scientific Publishing
Hydrogen Adsorption in Metal-Organic Framework MIL-101(Cr) - Adsorbate Densities and Enthalpies from Sorption, Neutron Scattering, <i>in Situ</i> X-ray Diffraction, Calorimetry, and Molecular Simulations
Nuno Bimbo, Kang Zhang, Himanshu Aggarwal, Timothy J. Mays, Jianwen Jiang, Leonard J. Barbour, Valeska P. Ting
Aug 23, 2021
In this paper, hydrogen adsorption in metal-organic framework MIL-101(Cr) is investigated through a combination of sorption experiments, modeling of experimental isotherms, differential scanning calorimetry (DSC), neutron...
adsorbed density enthalpies of adsorption Hydrogen storage inelastic neutron scattering metal-organic frameworks MIL-101(Cr) /dk/atira/pure/subjectarea/asjc/1500/1501 name=Chemical Engineering (miscellaneous) /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1603 name=Electrochemistry /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry
Algorithmic Analysis of Automatic Attendance System Using Facial Recognition
Attendance management can become a tedious task for teachers if it is performed manually. This problem can be solved with the help of an automatic attendance management system. But validation is one of the main issues in the...
Published by: IGI Global Scientific Publishing
Controlling aggregation of cholesterol-modified DNA nanostructures.
Alexander Ohmann, Kerstin Göpfrich, Himanshu Joshi, Rebecca F Thompson, Diana Sobota, Neil A Ranson, Aleksei Aksimentiev, Ulrich F Keyser
Oct 08, 2019
Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly.
Lili Arabuli, Igor A Iashchishyn, Nina V Romanova, Greta Musteikyte, Vytautas Smirnovas, Himanshu Chaudhary, Željko M Svedružić, Ludmilla A Morozova-Roche
Aug 11, 2021
The amyloid cascade is central for the neurodegeneration disease pathology, including Alzheimer's and Parkinson's, and remains the focus of much current research. S100A9 protein drives the amyloid-neuroinflammatory cascade in...
Knowledge Extraction in Digit Recognition Using MNIST Dataset
Rohit Rastogi, Akshit Rastogi, Himanshu Upadhyay, Divya Sharma, Prankur Bishnoi, Ankit Kumar, Abhinav Tyagi
Oct 01, 2021
In handwriting recognition, traditional systems have relied heavily on handcrafted features and a massive amount of prior data and knowledge. Deep learning techniques have been the focus of research in the field of handwriting...
Published by: IGI Global Scientific Publishing
A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder
Himanshu Tyagi, Annemieke M Apergis-Schoute, Harith Akram, Tom Foltynie, Patricia Limousin, Lynne M Drummond, Naomi A Fineberg, Keith Matthews, Marjan Jahanshahi, Trevor W Robbins, Barbara J Sahakian, Ludvic Zrinzo, Marwan Hariz, Eileen M Joyce
May 07, 2019
BACKGROUND: Deep brain stimulation (DBS) is an emerging treatment for severe obsessive-compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal (VC/VS) and anteromedial subthalamic nucleus (amSTN)...
Anteromedial subthalamic nucleus DBS Deep Brain Stimulation OCD Obsessive-Compulsive Disorder Ventral internal capsule Adult Deep Brain Stimulation Double-Blind Method Female Humans Magnetic Resonance Imaging Male Middle Aged Obsessive-Compulsive Disorder Subthalamic nucleus Treatment Outcome Ventral Striatum
DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency.
Clare V Logan, Jennie E Murray, David A Parry, Andrea Robertson, Roberto Bellelli, Žygimantė Tarnauskaitė, Rachel Challis, Louise Cleal, Valerie Borel, Adeline Fluteau, Javier Santoyo-Lopez, SGP Consortium, Tim Aitman, Inês Barroso, Donald Basel, Louise S Bicknell, Himanshu Goel, Hao Hu, Chad Huff, Michele Hutchison, Caroline Joyce, Rachel Knox, Amy E Lacroix, Sylvie Langlois, Shawn McCandless, Julie McCarrier, Kay A Metcalfe, Rose Morrissey, Nuala Murphy, Irène Netchine, Susan M O'Connell, Ann Haskins Olney, Nandina Paria, Jill A Rosenfeld, Mark Sherlock, Erin Syverson, Perrin C White, Carol Wise, Yao Yu, Margaret Zacharin, Indraneel Banerjee, Martin Reijns, Michael B Bober, Robert K Semple, Simon J Boulton, Jonathan J Rios, Andrew P Jackson
Jul 18, 2019
During genome replication, polymerase epsilon (Pol ε) acts as the major leading-strand DNA polymerase. Here we report the identification of biallelic mutations in POLE, encoding the Pol ε catalytic subunit POLE1, in 15...
DNA Replication IMAGe syndrome adrenal failure Cell Cycle growth immunodeficiency Microcephaly polymerase epsilon Adolescent Adrenal Insufficiency Adult Alleles Child Child Preschool Cyclin-Dependent Kinase Inhibitor p57 DNA Polymerase II DNA Replication Female Fetal Growth Retardation Humans Infant Male Middle Aged Mutation Osteochondrodysplasias Phenotype Poly-ADP-Ribose Binding Proteins Urogenital Abnormalities Young Adult
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease
Lindsey Van Haute, Emily O’Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella H Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha S Zaki, Alban Ziegler, David R Thorburn, David A Stroud, Reza Maroofian, John Christodoulou, Claes Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
Feb 23, 2023
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