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Pressure-stabilized divalent ozonide CaO3 and its impact on Earth's oxygen cycles.
Yanchao Wang, Meiling Xu, Liuxiang Yang, Bingmin Yan, Qin Qin, Xuecheng Shao, Yunwei Zhang, Dajian Huang, Xiaohuan Lin, Jian Lv, Dongzhou Zhang, Huiyang Gou, Ho-Kwang Mao, Changfeng Chen, Yanming Ma
Nov 16, 2020
High pressure can drastically alter chemical bonding and produce exotic compounds that defy conventional wisdom. Especially significant are compounds pertaining to oxygen cycles inside Earth, which hold key to understanding...
Evaluation of an explanted porcine skin model to investigate infection with the dermatophyte Trichophyton rubrum.
Dermatophytosis is a fungal infection of skin, hair and nails, and the most frequently found causative agent is Trichophyton rubrum. The disease is very common and often recurring, and it is therefore difficult to eradicate. To...
Antifungals Dermatophytes Explanted porcine skin Skin infection model Trichophyton rubrum /dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2400/2402 name=Applied Microbiology and Biotechnology /dk/atira/pure/subjectarea/asjc/1100/1102 name=Agronomy and Crop Science /dk/atira/pure/subjectarea/asjc/3400/3401 name=veterinary (miscalleneous) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Evaluation of an explanted porcine skin model to investigate infection with the dermatophyte Trichophyton rubrum.
Dermatophytosis is a fungal infection of skin, hair and nails, and the most frequently found causative agent is Trichophyton rubrum. The disease is very common and often recurring, and it is therefore difficult to eradicate. To...
Antifungals Dermatophytes Explanted porcine skin Skin infection model Trichophyton rubrum /dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2400/2402 name=Applied Microbiology and Biotechnology /dk/atira/pure/subjectarea/asjc/1100/1102 name=Agronomy and Crop Science /dk/atira/pure/subjectarea/asjc/3400/3401 name=veterinary (miscalleneous) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Development of refractoriness of ho-1 induction to a second treatment with uva radiation and the involvement of nrf2 in human skin fibroblasts
Julia Li Zhong, Chintan M. Raval, Muhammad Farrukh Nisar, ChunXiang Bian, Jin Zhang, Li Yang, Rex M. Tyrrell
Nov 01, 2014
UVA treatment of cultured human skin fibroblasts (FEK4) has been shown previously to reduce transcriptional activation of heme oxygenase 1 (HO-1) following a second dose of UVA radiation, a phenomenon known as refractoriness....
A microtiter plate-based quantitative method to monitor the growth rate of dermatophytes and test antifungal activity
Dermatophytosis is one of the most common superficial fungal infections, which is mainly caused by filamentous fungi such as Trichophyton species. A challenging aspect in dermatophyte research is the lack of a straightforward...
A microtiter plate-based quantitative method to monitor the growth rate of dermatophytes and test antifungal activity
Dermatophytosis is one of the most common superficial fungal infections, which is mainly caused by filamentous fungi such as Trichophyton species. A challenging aspect in dermatophyte research is the lack of a straightforward...
Development of refractoriness of ho-1 induction to a second treatment with uva radiation and the involvement of nrf2 in human skin fibroblasts
Julia Li Zhong, Chintan M. Raval, Muhammad Farrukh Nisar, ChunXiang Bian, Jin Zhang, Li Yang, Rex M. Tyrrell
Nov 01, 2014
UVA treatment of cultured human skin fibroblasts (FEK4) has been shown previously to reduce transcriptional activation of heme oxygenase 1 (HO-1) following a second dose of UVA radiation, a phenomenon known as refractoriness....
Retrospective analysis assessing the spatial and temporal distribution of paediatric acute respiratory tract infections in Ho Chi Minh City, Vietnam.
Nhan Thi Ho, Corinne Thompson, Le Nguyen Thanh Nhan, Hoang Minh Tu Van, Nguyen Thanh Dung, Phuc Tran My, Vo Minh Quang, Ngo Ngoc Quang Minh, Tran Anh Tuan, Nguyen Thanh Hung, Ha Manh Tuan, Nguyen Van Vinh Chau, Marcel Wolbers, Guy E Thwaites, Marc Choisy, Stephen Baker
Apr 10, 2019
BACKGROUND: Acute respiratory tract infections (ARIs) are the leading cause of morbidity and mortality in young children in low/middle-income countries. Using routine hospital data, we aimed to examine the spatial distribution...
acute respiratory infections lower respiratory infections Pediatrics spatial distribution Temporal patterns upper respiratory infections Acute Disease Adolescent Child Child Preschool Female Hospitalization Hospitals Pediatric Humans Incidence Infant Infant Newborn Male Respiratory Tract Infections Retrospective Studies Risk Factors Seasons Spatio-Temporal Analysis Vietnam weather
Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation.
Aslihan Ugun-Klusek, Theodosis S Theodosi, Julia C Fitzgerald, Florence Burté, Christoph Ufer, David J Boocock, Patrick Yu-Wai-Man, Lynn Bedford, E Ellen Billett
Dec 07, 2018
Monoamine oxidases (MAOs) are located on the outer mitochondrial membrane and are drug targets for the treatment of neurological disorders. MAOs control the levels of neurotransmitters in the brain via oxidative deamination and...
Autophagy Monoamine Oxidase neurodegeneration Reactive Oxygen Species Autophagy Caspases Cell Line Tumor Cell Survival Fluorescent Antibody Technique Gene Expression Humans Immunohistochemistry Mitochondria Models Biological Monoamine Oxidase Neuroblastoma Oxidation-Reduction Oxidative Stress Phosphorylation Proteome Proteomics Proto-Oncogene Proteins c-bcl-2 Reactive Oxygen Species
Biphasic pattern in the effect of severe measles infection; the difference between additive and multiplicative scale.
BACKGROUND: Infection with measles virus (MeV) causes immunosuppression and increased susceptibility to other infectious diseases. Only few studies reported a duration of immunosuppression, with varying results. We investigated...
Biphasic pattern in the effect of severe measles infection; the difference between additive and multiplicative scale.
BACKGROUND: Infection with measles virus (MeV) causes immunosuppression and increased susceptibility to other infectious diseases. Only few studies reported a duration of immunosuppression, with varying results. We investigated...
Technological Factors Affecting Communication Quality at Ho Chi Minh City University of Industry and Trade
In the current era of technological explosion, applications are widely adopted and continuously improved, significantly impacting the education sector and creating a high demand for training within educational institutions. This...
Published by: IGI Global Scientific Publishing
Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes.
Soni Deshwal, Marleen Forkink, Chou-Hui Hu, Guido Buonincontri, Salvatore Antonucci, Moises Di Sante, Michael P Murphy, Nazareno Paolocci, Daria Mochly-Rosen, Thomas Krieg, Fabio Di Lisa, Nina Kaludercic
May 14, 2018
Monoamine oxidase (MAO) inhibitors ameliorate contractile function in diabetic animals, but the mechanisms remain unknown. Equally elusive is the interplay between the cardiomyocyte alterations induced by hyperglycemia and the...
Animals Cell Degranulation Diabetes mellitus Experimental Endoplasmic reticulum stress Glucose Interleukin-1beta Male Mice Mice Inbred C57BL Mitochondria Mitochondrial Membrane Transport Proteins Mitochondrial Permeability Transition Pore Monoamine Oxidase Monoamine Oxidase Inhibitors Muscle Cells Myocardium RNA Interference RNA Small Interfering Rats Reactive Oxygen Species Ventricular Remodeling
Utility of targeted deep sequencing for detecting circulating tumor DNA in pancreatic cancer patients.
Gahee Park, Joo Kyung Park, Dae-Soon Son, Seung-Ho Shin, Yeon Jeong Kim, Hyo-Jeong Jeon, Jae Lee, Woong-Yang Park, Kwang Hyuck Lee, Donghyun Park
Nov 07, 2018
Targeted deep sequencing across broad genomic regions has been used to detect circulating tumor DNA (ctDNA) in pancreatic ductal adenocarcinoma (PDAC) patients. However, since most PDACs harbor a mutation in KRAS, sequencing of...
Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life
Ji-Yeon Lee, Kyungdo Han, Eugene Han, Gyuri Kim, Hanna Cho, Kwang Joon Kim, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Carol Brayne, Yong-Ho Lee
Mar 15, 2019
CONTEXT: The risk for dementia among subjects who are obese with normal metabolic profiles, or called metabolically healthy obese (MHO), remains uninvestigated. OBJECTIVE: To determine the association between late-life metabolic...
Aged Alzheimer Disease Blood Glucose Cholesterol HDL Cholesterol LDL Cohort Studies Comorbidity Dementia Dementia Vascular Diabetes mellitus Female Humans Hyperlipidemias Hypertension Incidence Male Metabolic Syndrome Middle Aged obesity obesity Metabolically Benign Renal Insufficiency Chronic Republic of Korea Retrospective Studies Risk Factors Thinness Triglycerides
microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma.
Julja Burchard, Chunsheng Zhang, Angela M Liu, Ronnie TP Poon, Nikki PY Lee, Kwong-Fai Wong, Pak C Sham, Brian Y Lam, Mark D Ferguson, George Tokiwa, Ryan Smith, Brendan Leeson, Rebecca Beard, John R Lamb, Lee Lim, Mao Mao, Hongyue Dai, John M Luk
Aug 08, 2017
Tumorigenesis involves multistep genetic alterations. To elucidate the microRNA (miRNA)-gene interaction network in carcinogenesis, we examined their genome-wide expression profiles in 96 pairs of tumor/non-tumor tissues from...
Animals Carcinoma Hepatocellular Cell Line Tumor Down-Regulation Energy Metabolism Gene Expression Profiling Gene Expression Regulation Neoplastic Gene Regulatory Networks Genes Mitochondrial Humans Liver Liver Neoplasms Mice Mice Inbred C57BL MicroRNAs Mitochondria RNA Messenger Reproducibility of Results Sequence Homology Nucleic Acid Signal Transduction Survival Analysis Up-Regulation
Incidence of heterotopic ossification following hip arthroscopy is low
PURPOSE: This scoping review aims to map and summarise the available literature on heterotopic ossification (HO) following hip arthroscopy, with particular focus on incidence, distribution as per Brooker classification, efficacy...
Exposing the Interplay Between Enzyme Turnover, Protein Dynamics and the Membrane Environment in Monoamine Oxidase B
Hannah B L Jones, Rory M Crean, Anna Mullen, Emanuele Kendrick, Steven D Bull, Stephen A Wells, David Ross Carbery, Fraser MacMillan, Marc W van der Kamp, Christopher Roland Pudney
May 07, 2019
There is an increasing realization that structure-based drug design may show improved success by understanding the ensemble of conformations accessible to an enzyme and how the environment affects this ensemble. Human...
Exposing the Interplay Between Enzyme Turnover, Protein Dynamics and the Membrane Environment in Monoamine Oxidase B
Hannah B L Jones, Rory M Crean, Anna Mullen, Emanuele Kendrick, Steven D Bull, Stephen A Wells, David Ross Carbery, Fraser MacMillan, Marc W van der Kamp, Christopher Roland Pudney
May 07, 2019
There is an increasing realization that structure-based drug design may show improved success by understanding the ensemble of conformations accessible to an enzyme and how the environment affects this ensemble. Human...
Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages.
Belén Prados, Raquel Del Toro, Donal MacGrogan, Paula Gómez-Apiñániz, Tania Papoutsi, Pura Muñoz-Cánoves, Simón Méndez-Ferrer, José Luis de la Pompa
Sep 08, 2021
Bone morphogenetic protein (Bmp) signaling is critical for organismal development and homeostasis. To elucidate Bmp2 function in the vascular/hematopoietic lineages we generated a new transgenic mouse line in which ectopic Bmp2...
Animals Aortic Valve Bone Marrow Transplantation Bone Morphogenetic Protein 2 Calcinosis Cell Lineage Chondrogenesis Endothelial Cells Hematopoiesis Hematopoietic Stem Cells Kaplan-Meier Estimate Mice Inbred C57BL Mice Transgenic Muscle Cells Ossification Heterotopic Osteogenesis Receptor TIE-2 Tomography X-Ray Computed
Public, Private, People Partnership Framework For Developing Indonesian Smart City Infrastructure
The development of smart cities is an essential aspect of sustainable cities, but this initiative demands many resources. To assist the development of smart cities, the public, private partnership (PPP) concept has proven to be...
Published by: Indonesia Strategic Sustainability
Moving the techno-science gap in Security Force Assistance
David Galbreath
Dec 31, 2019
This paper looks at the impact of military technology diffusion on military assistance operations (MAO), in the United States known as Security Force Assistance or SFA. The discussion looks conceptually at the role of...
Moving the techno-science gap in Security Force Assistance
David Galbreath
Dec 31, 2019
This paper looks at the impact of military technology diffusion on military assistance operations (MAO), in the United States known as Security Force Assistance or SFA. The discussion looks conceptually at the role of...
The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia.
Red cells from patients with sickle cell anemia (SCA) are under greater oxidative challenge than those from normal individuals. We postulated that oxidants generated by xanthine oxidase (XO) and hypoxanthine (HO) contribute to...
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