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Results: 6
The Firre locus produces a trans -acting RNA molecule that functions in hematopoiesis
Jordan P. Lewandowski, James C. Lee, Taeyoung Hwang, Hongjae Sunwoo, Jill M. Goldstein, Abigail F. Groff, Nydia P. Chang, William Mallard, Adam Williams, Jorge Henao-Meija, Richard A. Flavell, Jeannie T. Lee, Chiara Gerhardinger, Amy J. Wagers, John L. Rinn
Nov 12, 2020
Abstract: RNA has been classically known to play central roles in biology, including maintaining telomeres, protein synthesis, and in sex chromosome compensation. While thousands of long noncoding RNAs (lncRNAs) have been...
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.
Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.
Sunwoo Lee, Eguzkine Ochoa, Katy Barwick, Laura Cif, Fay Rodger, France Docquier, Belén Pérez-Dueñas, Graeme Clark, Ezequiel Martin, Siddharth Banka, Manju A Kurian, Eamonn R Maher
May 17, 2022
Kabuki syndrome chromatin disorders early-onset dystonia histone lysine methyltransferases (KMTs) Methylation neurodevelopmental disorder Abnormalities Multiple DNA Methylation DNA-Binding Proteins Face Hematologic Diseases Histone-Lysine N-Methyltransferase Humans Mutation Neoplasm Proteins Phenotype Vestibular Diseases
Molecular characterisation of 36 multilocus imprinting disturbance (MLID) patients
Larissa Bilo, Eguzkine Ochoa, Sunwoo Lee, Daniela Dey, Ingo Kurth, Florian Kraft, Fay Rodger, France Docquier, Ana Toribio, Leonardo Bottolo, Gerhard Binder, György Fekete, Miriam Elbracht, Eamonn R Maher, Matthias Begemann, Thomas Eggermann
Apr 01, 2023
BACKGROUND: Imprinting disorders (ImpDis) comprise diseases which are caused by aberrant regulation of monoallelically and parent-of-origin-dependent expressed genes. A characteristic molecular change in ImpDis patients is...
Molecular characterisation of 36 multilocus imprinting disturbance (MLID) patients