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Results: 27
Cell graph neural networks enable the precise prediction of patient survival in gastric cancer.
Yanan Wang, Yu Guang Wang, Changyuan Hu, Ming Li, Yanan Fan, Nina Otter, Ikuan Sam, Hongquan Gou, Yiqun Hu, Terry Kwok, John Zalcberg, Alex Boussioutas, Roger J Daly, Guido Montúfar, Pietro Lio, Dakang Xu, Geoffrey I Webb, Jiangning Song
Jun 29, 2022
Gastric cancer is one of the deadliest cancers worldwide. An accurate prognosis is essential for effective clinical assessment and treatment. Spatial patterns in the tumor microenvironment (TME) are conceptually indicative of...
Cell graph neural networks enable the precise prediction of patient survival in gastric cancer.
Yanan Wang, Yu Guang Wang, Changyuan Hu, Ming Li, Yanan Fan, Nina Otter, Ikuan Sam, Hongquan Gou, Yiqun Hu, Terry Kwok, John Zalcberg, Alex Boussioutas, Roger J Daly, Guido Montúfar, Pietro Liò, Dakang Xu, Geoffrey I Webb, Jiangning Song
Jul 24, 2022
Gastric cancer is one of the deadliest cancers worldwide. An accurate prognosis is essential for effective clinical assessment and treatment. Spatial patterns in the tumor microenvironment (TME) are conceptually indicative of...
Existence of Mild Solutions for Fractional Nonlocal Evolution Equations With Delay in Partially Ordered Banach Spaces
This paper deals with the existence of mild solutions for the abstract fractional nonlocal evolution equations with noncompact semigroup in partially ordered Banach spaces. Under some mixed conditions, a group of sufficient...
Published by: Digital Commons @ Texas A&M University-San Antonio
A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks
Glimm et al. (2010) and Tamhane et al. (2010) studied the problem of testing a primary and a secondary endpoint, subject to a gatekeeping constraint, using a group sequential design (GSD) with K=2 looks. In this article, we...
familywise error rate Gatekeeping Lan-DeMets error spending function approach Multiple comparisons Multiple endpoints O'Brien-Fleming boundary Pocock boundary Primary power Secondary power /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2700/2700 name=General Medicine /dk/atira/pure/subjectarea/asjc/2400/2400 name=General Immunology and Microbiology /dk/atira/pure/subjectarea/asjc/1300/1300 name=General Biochemistry,Genetics and Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1100 name=General Agricultural and Biological Sciences /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Growth-profile configuration for specific deformations of tubular organs
Growth is a significant factor that results in deformations of tubular organs, and particular deformations associated with growth enable tubular organs to perform certain physiological functions. Configuring growth profiles that...
Published by: Digital Commons @ Texas A&M University-San Antonio
Growth-profile configuration for specific deformations of tubular organs
Growth is a significant factor that results in deformations of tubular organs, and particular deformations associated with growth enable tubular organs to perform certain physiological functions. Configuring growth profiles that...
Published by: Digital Commons @ Texas A&M University-San Antonio
The duration-energy-size enigma for acoustic emission
Abstract: Acoustic emission (AE) measurements of avalanches in different systems, such as domain movements in ferroics or the collapse of voids in porous materials, cannot be compared with model predictions without a detailed...
Existence of Mild Solutions for Fractional Nonlocal Evolution Equations With Delay in Partially Ordered Banach Spaces
This paper deals with the existence of mild solutions for the abstract fractional nonlocal evolution equations with noncompact semigroup in partially ordered Banach spaces. Under some mixed conditions, a group of sufficient...
Published by: Digital Commons @ Texas A&M University-San Antonio
A Blockchain-Based Security Model for Cloud Accounting Data
The popularity of cloud accounting is due to its low cost of entry, efficient data processing, and high business efficiency. However, security issues in cloud storage can affect user trust in the service. To address these...
Published by: IGI Global Scientific Publishing
A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks
Glimm et al. (2010) and Tamhane et al. (2010) studied the problem of testing a primary and a secondary endpoint, subject to a gatekeeping constraint, using a group sequential design (GSD) with K=2 looks. In this article, we...
familywise error rate Gatekeeping Lan-DeMets error spending function approach Multiple comparisons Multiple endpoints O'Brien-Fleming boundary Pocock boundary Primary power Secondary power /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2700/2700 name=General Medicine /dk/atira/pure/subjectarea/asjc/2400/2400 name=General Immunology and Microbiology /dk/atira/pure/subjectarea/asjc/1300/1300 name=General Biochemistry,Genetics and Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1100 name=General Agricultural and Biological Sciences /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Existence of Mild Solutions for Fractional Nonlocal Evolution Equations With Delay in Partially Ordered Banach Spaces
This paper deals with the existence of mild solutions for the abstract fractional nonlocal evolution equations with noncompact semigroup in partially ordered Banach spaces. Under some mixed conditions, a group of sufficient...
Published by: Digital Commons @ Texas A&M University-San Antonio
Growth-profile configuration for specific deformations of tubular organs
Growth is a significant factor that results in deformations of tubular organs, and particular deformations associated with growth enable tubular organs to perform certain physiological functions. Configuring growth profiles that...
Published by: Digital Commons @ Texas A&M University-San Antonio
The duration-energy-size enigma for acoustic emission.
Acoustic emission (AE) measurements of avalanches in different systems, such as domain movements in ferroics or the collapse of voids in porous materials, cannot be compared with model predictions without a detailed analysis of...
Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies.
Jin Gao, Laura Couzens, David F Burke, Hongquan Wan, Patrick Wilson, Matthew J Memoli, Xiyan Xu, Ruth Harvey, Jens Wrammert, Rafi Ahmed, Jeffery K Taubenberger, Derek J Smith, Ron AM Fouchier, Maryna C Eichelberger
Apr 16, 2019
The effectiveness of influenza vaccines against circulating A(H1N1)pdm09 viruses was modest for several seasons despite the absence of antigenic drift of hemagglutinin (HA), the primary vaccine component. Since antibodies...
Antigenic drift Influenza Monoclonal antibodies Neuraminidase vaccines Animals Antibodies Monoclonal Antibodies Viral Antigens Viral Disease Models Animal Ferrets Genetic Drift Immune Evasion Immunization Passive Influenza A virus H1N1 Subtype Mice Neuraminidase Orthomyxoviridae Infections Survival Analysis Treatment Outcome Viral Proteins
An ultra-low-loss superconducting inductor for power electronic circuits
Abstract: To break through the bottlenecks of the loss and size of conventional conductors and magnetic materials, replacing copper inductors by zero‐resistance superconducting inductors can be a promising solution. The...
Affordances and Constraints of Automation and Augmentation
Human-AI collaboration is becoming increasingly prevalent in workplaces, and is considered to be an important model for the future of work. Consequently, AI is no longer seen merely as a tool but as a teammate working alongside...
Published by: IGI Global Scientific Publishing
Pressure-stabilized divalent ozonide CaO3 and its impact on Earth's oxygen cycles.
Yanchao Wang, Meiling Xu, Liuxiang Yang, Bingmin Yan, Qin Qin, Xuecheng Shao, Yunwei Zhang, Dajian Huang, Xiaohuan Lin, Jian Lv, Dongzhou Zhang, Huiyang Gou, Ho-Kwang Mao, Changfeng Chen, Yanming Ma
Nov 16, 2020
High pressure can drastically alter chemical bonding and produce exotic compounds that defy conventional wisdom. Especially significant are compounds pertaining to oxygen cycles inside Earth, which hold key to understanding...
The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases.
Fengzhe Xu, Yuanqing Fu, Ting-yu Sun, Zengliang Jiang, Zelei Miao, Menglei Shuai, Wanglong Gou, Chu-wen Ling, Jian Yang, Jun Wang, Yu-ming Chen, Ju-Sheng Zheng
Oct 08, 2021
BACKGROUND: Interest in the interplay between host genetics and the gut microbiome in complex human diseases is increasing, with prior evidence mainly being derived from animal models. In addition, the shared and distinct...
Bidirectional Mendelian randomization analyses Disease-microbiome features gut microbiome Host genetics Adult Aged Animals Case-Control Studies Disease Female Gastrointestinal Microbiome Genome-Wide Association Study Humans Leukemia Myelogenous Chronic BCR-ABL Positive Lupus Erythematosus Systemic Male Middle Aged
Erythrocyte n-6 Polyunsaturated Fatty Acids, Gut Microbiota, and Incident Type 2 Diabetes
Zelei Miao, Jie-Sheng Lin, Yingying Mao, Geng-Dong Chen, Fang-Fang Zeng, Hong-Li Dong, Zengliang Jiang, Jiali Wang, Congmei Xiao, Menglei Shuai, Wanglong Gou, Yuanqing Fu, Fumiaki Imamura, Yu-ming Chen, Ju-Sheng Zheng
Jul 14, 2020
The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases
Fengzhe Xu, Yuanqing Fu, Ting-yu Sun, Zengliang Jiang, Zelei Miao, Menglei Shuai, Wanglong Gou, Chu-wen Ling, Jian Yang, Jun Wang, Yu-ming Chen, Ju-Sheng Zheng
Oct 08, 2020
Abstract: Background: Interest in the interplay between host genetics and the gut microbiome in complex human diseases is increasing, with prior evidence mainly being derived from animal models. In addition, the shared and...
Control of endothelial quiescence by FOXO-regulated metabolites.
Jorge Andrade, Chenyue Shi, Ana SH Costa, Jeongwoon Choi, Jaeryung Kim, Anuradha Doddaballapur, Toshiya Sugino, Yu Ting Ong, Marco Castro, Barbara Zimmermann, Manuel Kaulich, Stefan Guenther, Kerstin Wilhelm, Yoshiaki Kubota, Thomas Braun, Gou Young Koh, Ana Rita Grosso, Christian Frezza, Michael Potente
Apr 09, 2021
Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility.
Fengzhe Xu, Evan Yi-Wen Yu, Xue Cai, Liang Yue, Li-Peng Jing, Xinxiu Liang, Yuanqing Fu, Zelei Miao, Min Yang, Menglei Shuai, Wanglong Gou, Congmei Xiao, Zhangzhi Xue, Yuting Xie, Sainan Li, Sha Lu, Meiqi Shi, Xuhong Wang, Wensheng Hu, Claudia Langenberg, Jian Yang, Yu-ming Chen, Tiannan Guo, Ju-Sheng Zheng
Mar 19, 2023
Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic...
Humans Cardiovascular Diseases Genetic Predisposition to Disease Proteome Genotype Phenotype Polymorphism Single Nucleotide Genome-Wide Association Study
Published by: Nature Communications
Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility.
Fengzhe Xu, Evan Yi-Wen Yu, Xue Cai, Liang Yue, Li-Peng Jing, Xinxiu Liang, Yuanqing Fu, Zelei Miao, Min Yang, Menglei Shuai, Wanglong Gou, Congmei Xiao, Zhangzhi Xue, Yuting Xie, Sainan Li, Sha Lu, Meiqi Shi, Xuhong Wang, Wensheng Hu, Claudia Langenberg, Jian Yang, Yu-ming Chen, Tiannan Guo, Ju-Sheng Zheng
Feb 17, 2023
Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic...
Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2.
Jeonghwan Youk, Taewoo Kim, Kelly V Evans, Young-Il Jeong, Yongsuk Hur, Seon Pyo Hong, Je Hyoung Kim, Kijong Yi, Su Yeon Kim, Kwon Joong Na, Thomas Bleazard, Ho Min Kim, Mick Fellows, Krishnaa T Mahbubani, Kourosh Saeb-Parsy, Seon Young Kim, Young Tae Kim, Gou Young Koh, Byeong-Sun Choi, Young Seok Ju, Joo-Hyeon Lee
Oct 15, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of a present pandemic, infects human lung alveolar type 2 (hAT2) cells. Characterizing pathogenesis is crucial for developing vaccines and...
3D cultures covid-19 SARS-CoV-2 alveolar stem cells Electron microscopy human alveolar type 2 cells Infection interferon interferon-stimulating genes Single-cell RNA-seq covid-19 Cell Culture Techniques Culture Media Humans Interferons Models Biological Pulmonary Alveoli SARS-CoV-2 Stem Cells Transcriptome Virus Internalization Virus Replication
Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System.
Elizabeth C Goode, Allan B Clark, George F Mells, Brijesh Srivastava, Kelly Spiess, William Th Gelson, Palak J Trivedi, Kate D Lynch, Edit Castren, Mette N Vesterhus, Tom H Karlsen, Sun-Gou Ji, Carl A Anderson, Douglas Thorburn, Mark Hudson, Michael A Heneghan, Mark A Aldersley, Andrew Bathgate, Richard N Sandford, Graeme J Alexander, Roger W Chapman, Martine Walmsley, UK-PSC Consortium, Gideon M Hirschfield, Simon M Rushbrook
Jan 08, 2019
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