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Results: 1007
Clinical and laboratory factors associated with neonatal sepsis mortality at a major Vietnamese children's hospital.
Nguyen Duc Toan, Thomas C Darton, Nguyen Hoang Thien Huong, Le Thanh Hoang Nhat, To Nguyen Thi Nguyen, Ha Thanh Tuyen, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Cam Ngoc Phuong, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Ngo Minh Xuan, Tang Chi Thuong, Nguyen Thanh Hung, Christine Boinett, Stephen Reece, Abhilasha Karkey, Jeremy N Day, Stephen Baker
Apr 17, 2023
Sepsis is a major cause of neonatal mortality and children born in low- and middle-income countries (LMICs) are at greater risk of severe neonatal infections than those in higher-income countries. Despite this disparity, there...
Published by: PLOS global public health
The emergence of azithromycin-resistant Salmonella Typhi in Nepal.
Pham Thanh Duy, Sabina Dongol, Abhishek Giri, Nguyen Thi Nguyen To, Ho Ngoc Dan Thanh, Nguyen Pham Nhu Quynh, Pham Duc Trung, Guy E Thwaites, Buddha Basnyat, Stephen Baker, Maia A Rabaa, Abhilasha Karkey
May 17, 2021
BACKGROUND: Typhoid fever remains a significant cause of morbidity and mortality in Asia and Africa. The emergence of azithromycin resistance in South Asia is concerning, as azithromycin is one of the last effective oral drugs...
Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.
Chau Le Ngoc, Thanh Tran Thi Thanh, Phuong Tran Thi Lan, Trinh Nguyen Mai, Trang Nguyen Hoa, Ngoc Nghiem My, Tan Le Van, Hung Le Manh, Phuong Le Thanh, Chau Nguyen Van Vinh, Guy Thwaites, Graham Cooke, Gabrielle M Heilek, Cecilia Shikuma, Thuy Le, Stephen Baker, Motiur Rahman, VIZIONS consortium
Apr 10, 2019
BACKGROUND: The highest burden of disease from hepatitis C virus (HCV) is found in Southeast Asia, but our understanding of the epidemiology of infection in many heavily burdened countries is still limited. In particular, there...
Clinical and laboratory factors associated with neonatal sepsis mortality at a major Vietnamese children's hospital.
Nguyen Duc Toan, Thomas C Darton, Nguyen Hoang Thien Huong, Le Thanh Hoang Nhat, To Nguyen Thi Nguyen, Ha Thanh Tuyen, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Cam Ngoc Phuong, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Ngo Minh Xuan, Tang Chi Thuong, Nguyen Thanh Hung, Christine Boinett, Stephen Reece, Abhilasha Karkey, Jeremy N Day, Stephen Baker
Sep 02, 2022
Sepsis is a major cause of neonatal mortality and children born in low- and middle-income countries (LMICs) are at greater risk of severe neonatal infections than those in higher-income countries. Despite this disparity, there...
Patient Safety Infant Mortality Hematology Sepsis Pediatric Clinical Research Infectious Diseases Perinatal Period - Conditions Originating in Perinatal Period 4.1 Discovery and preclinical testing of markers and technologies 4 Detection screening and diagnosis Infection Inflammatory and immune system 3 Good Health and Well Being
Clinical features, antimicrobial susceptibility patterns and genomics of bacteria causing neonatal sepsis in a children's hospital in Vietnam
Nguyen Duc Toan, Thomas C Darton, Christine J Boinett, James I Campbell, Abhilasha Karkey, Evelyne Kestelyn, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Cam Ngoc Phuong, Nguyen Thanh Hung, Ngo Minh Xuan, Tang Chi Thuong, Stephen Baker
Apr 10, 2019
INTRODUCTION: The clinical syndrome of neonatal sepsis, comprising signs of infection, septic shock and organ dysfunction in infants ≤4 weeks of age, is a frequent sequel to bloodstream infection and mandates urgent...
Antimicrobial resistance clinical features Genomics neonates outcomes Sepsis Anti-Infective Agents Bacteria Drug Resistance Multiple Bacterial Female Hospitals Pediatric Humans Infant Infant Newborn Linear Models Male Microbial Sensitivity Tests Neonatal Sepsis Phylogeny Prospective Studies Research Design Vietnam whole genome sequencing
Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients.
Hoang NH Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E Thwaites, Lindsay J Hall, Daniel J Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Nov 28, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of...
A tightly clustered hepatitis E virus genotype 1a is associated with endemic and outbreak infections in Bangladesh.
Trang Nguyen Hoa, Saif Ullah Munshi, Khanh Nguyen Ngoc, Chau Le Ngoc, Thanh Tran Thi Thanh, Tahmina Akther, Shahina Tabassum, Nilufa Parvin, Stephen Baker, Motiur Rahman
Oct 04, 2021
BACKGROUND: Hepatitis E virus (HEV) infection is endemic in Bangladesh and there are occasional outbreaks. The molecular characteristics and pathogenesis of endemic and outbreak HEV strains are poorly understood. We compared the...
A tightly clustered hepatitis E virus genotype 1a is associated with endemic and outbreak infections in Bangladesh.
Trang Nguyen Hoa, Saif Ullah Munshi, Khanh Nguyen Ngoc, Chau Le Ngoc, Thanh Tran Thi Thanh, Tahmina Akther, Shahina Tabassum, Nilufa Parvin, Stephen Baker, Motiur Rahman
Aug 26, 2021
Background
Hepatitis E virus (HEV) infection is endemic in Bangladesh and there are occasional outbreaks. The molecular characteristics and pathogenesis of endemic and outbreak HEV strains are poorly understood. We...
Published by: PLOS ONE
A genomic snapshot of Salmonella enterica serovar Typhi in Colombia.
Paula Diaz Guevara, Mailis Maes, Duy Pham Thanh, Carolina Duarte, Edna Catering Rodriguez, Lucy Angeline Montaño, Thanh Ho Ngoc Dan, To Nguyen Thi Nguyen, Megan E Carey, Josefina Campos, Isabel Chinen, Enrique Perez, Stephen Baker
Nov 15, 2021
Little is known about the genetic diversity of Salmonella enterica serovar Typhi (S. Typhi) circulating in Latin America. It has been observed that typhoid fever is still endemic in this part of the world; however, a lack of...
A genomic snapshot of Salmonella enterica serovar Typhi in Colombia.
Paula Diaz Guevara, Mailis Maes, Duy Pham Thanh, Carolina Duarte, Edna Catering Rodriguez, Lucy Angeline Montaño, Thanh Ho Ngoc Dan, To Nguyen Thi Nguyen, Megan E Carey, Josefina Campos, Isabel Chinen, Enrique Perez, Stephen Baker
Oct 18, 2021
Published by: PLoS neglected tropical diseases
No Clinical Benefit of Empirical Antimicrobial Therapy for Pediatric Diarrhea in a High-Usage, High-Resistance Setting.
Vu Thuy Duong, Ha Thanh Tuyen, Pham Van Minh, James I Campbell, Hoang Le Phuc, Tran Do Hoang Nhu, Le Thi Phuong Tu, Tran Thi Hong Chau, Le Thi Quynh Nhi, Nguyen Thanh Hung, Nguyen Minh Ngoc, Nguyen Thi Thanh Huong, Lu Lan Vi, Corinne N Thompson, Guy E Thwaites, Ruklanthi de Alwis, Stephen Baker
Apr 10, 2019
BACKGROUND: Pediatric diarrheal disease presents a major public health burden in low- to middle-income countries. The clinical benefits of empirical antimicrobial treatment for diarrhea are unclear in settings that lack reliable...
Campylobacter Shigella Antimicrobial resistance disease outcome Fluoroquinolones multidrug resistance nontyphoidal Salmonella pediatric diarrhea Adolescent Anti-Bacterial Agents Campylobacter Child Child Preschool Cross-Sectional Studies Diarrhea Drug Resistance Multiple Bacterial Feces Female Humans Infant Male Microbial Sensitivity Tests prevalence Prospective Studies salmonella Shigella Treatment Outcome Vietnam
A tightly clustered hepatitis E virus genotype 1a is associated with endemic and outbreak infections in Bangladesh
Trang Nguyen Hoa, Saif Ullah Munshi, Khanh Nguyen Ngoc, Chau Le Ngoc, Thanh Tran Thi Thanh, Tahmina Akther, Shahina Tabassum, Nilufa Parvin, Stephen Baker, Motiur Rahman
Jul 28, 2021
A genomic snapshot of Salmonella enterica serovar Typhi in Colombia
Paula Diaz Guevara, Mailis Maes, Duy Pham Thanh, Carolina Duarte, Edna Catering Rodriguez, Lucy Angeline Montaño, Thanh Ho Ngoc Dan, To Nguyen Thi Nguyen, Megan E. Carey, Josefina Campos, Isabel Chinen, Enrique Perez, Stephen Baker
Sep 28, 2021
Pathogenic Escherichia coli Possess Elevated Growth Rates under Exposure to Sub-Inhibitory Concentrations of Azithromycin.
Tran Tuan-Anh, Ha Thanh Tuyen, Nguyen Ngoc Minh Chau, Nguyen Duc Toan, Tran Hanh Triet, Le Minh Triet, Nguyen Hoang Thu Trang, Nguyen Thi Nguyen To, Josefin Bartholdson Scott, Hao Chung The, Duy Pham Thanh, Hannah Clapham, Stephen Baker
Dec 07, 2020
Antimicrobial resistance (AMR) has been identified by the World Health Organization (WHO) as one of the ten major threats to global health. Advances in technology, including whole-genome sequencing, have provided new insights...
Excess body weight and age associated with the carriage of fluoroquinolone and third-generation cephalosporin resistance genes in commensal Escherichia coli from a cohort of urban Vietnamese children.
Le Thi Quynh Nhi, Ha Thanh Tuyen, Pham Duc Trung, Tran Do Hoang Nhu, Pham Thanh Duy, Chung The Hao, Nguyen Thi Thanh Nhan, Lu Lan Vi, Hoang Thi Diem Tuyet, Tran Thi Thuy Tien, Nguyen Van Vinh Chau, Phung Khanh Lam, Guy Thwaites, Stephen Baker
Apr 10, 2019
PURPOSE: Antimicrobial-resistant bacterial infections in low- and middle-income countries (LMICs) are a well-established global health issue. We aimed to assess the prevalence of and epidemiological factors associated with the...
EBSL Vietnam Antimicrobial resistance co-selection cohort Fluoroquinolones plasmid mediated quinolone resistance third generation cephalosporins Age Factors Anti-Bacterial Agents Body Weight Carrier State Child Preschool ciprofloxacin Drug Resistance Bacterial Escherichia coli Escherichia coli Infections Feces Female Fluoroquinolones Humans Male Microbial Sensitivity Tests Prospective Studies Vietnam
Viral Metagenomic Analysis of Cerebrospinal Fluid from Patients with Acute Central Nervous System Infections of Unknown Origin, Vietnam.
Nguyen To Anh, Le Nguyen Truc Nhu, Nguyen Thi Thu Hong, Tran My Phuc, Pham Thi Thanh Tam, Dang Thao Huong, Tran Tuan Anh, Xutao Deng, Ho Dang Trung Nghia, Tran Thua Nguyen, Nguyen Van Hung, Nguyen Dac Thuan, Pham Thi Hong Phuong, Nguyen Van Vinh Chau, Stephen Baker, Eric Delwart, Guy Thwaites, Le Van Tan, VIZIONS Consortium1
May 17, 2021
Central nervous system (CNS) infection is a serious neurologic condition, although the etiology remains unknown in >50% of patients. We used metagenomic next-generation sequencing to detect viruses in 204 cerebrospinal fluid...
Retrospective analysis assessing the spatial and temporal distribution of paediatric acute respiratory tract infections in Ho Chi Minh City, Vietnam.
Nhan Thi Ho, Corinne Thompson, Le Nguyen Thanh Nhan, Hoang Minh Tu Van, Nguyen Thanh Dung, Phuc Tran My, Vo Minh Quang, Ngo Ngoc Quang Minh, Tran Anh Tuan, Nguyen Thanh Hung, Ha Manh Tuan, Nguyen Van Vinh Chau, Marcel Wolbers, Guy E Thwaites, Marc Choisy, Stephen Baker
Apr 10, 2019
BACKGROUND: Acute respiratory tract infections (ARIs) are the leading cause of morbidity and mortality in young children in low/middle-income countries. Using routine hospital data, we aimed to examine the spatial distribution...
acute respiratory infections lower respiratory infections Pediatrics spatial distribution Temporal patterns upper respiratory infections Acute Disease Adolescent Child Child Preschool Female Hospitalization Hospitals Pediatric Humans Incidence Infant Infant Newborn Male Respiratory Tract Infections Retrospective Studies Risk Factors Seasons Spatio-Temporal Analysis Vietnam weather
Pathogenic Escherichia coli Possess Elevated Growth Rates under Exposure to Sub-Inhibitory Concentrations of Azithromycin
Tran Tuan-Anh, Ha Thanh Tuyen, Nguyen Ngoc Minh Chau, Nguyen Duc Toan, Tran Hanh Triet, Le Minh Triet, Nguyen Hoang Thu Trang, Nguyen Thi Nguyen To, Josefin Bartholdson Scott, Hao Chung The, Duy Pham Thanh, Hannah Clapham, Stephen Baker
Oct 29, 2020
Antimicrobial resistance (AMR) has been identified by the World Health Organization (WHO) as one of the ten major threats to global health. Advances in technology, including whole-genome sequencing, have provided new insights...
Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients.
Hoang NH Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E Thwaites, Lindsay J Hall, Daniel J Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Oct 29, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of...
Assessing the efficacy and safety of magnesium sulfate for management of autonomic nervous system dysregulation in Vietnamese children with severe hand foot and mouth disease.
Qui Tu Phan, Lam Khanh Phung, Khanh Huu Truong, Trieu Trung Huynh, Giang Thanh Phạm, Bich Ngọc Nguyen, Quyen Thanh Tran, Vuong Ngoc Thien Huynh, Tien Thi My Nguyen, Thoa Phan Kim Le, Nhan Nguyen Thanh Le, Saraswathy Sabanathan, H Rogier van Doorn, Tan Van Le, Toan Duc Nguyen, Laura Merson, Dung Thi Phuong Nguyen, Ronald Geskus, Hung Thanh Nguyen, Chau Van Vinh Nguyen, Bridget Wills
Aug 24, 2020
BACKGROUND: Brainstem encephalitis is a serious complication of hand foot and mouth disease (HFMD) in children. Autonomic nervous system (ANS) dysregulation and hypertension may occur, sometimes progressing to cardiopulmonary...
Autonomic nervous system dysregulation Brainstem encephalitis clinical trial Hand foot and mouth disease Hypertension Magnesium sulfate Animals Autonomic Nervous System Autonomic Nervous System Diseases Child Child Preschool Cohort Studies Disease Progression Double-Blind Method Female Hand Foot and Mouth Disease Hemodynamics Humans Infant Magnesium sulfate Male Placebos
Structure of general-population antibody titer distributions to influenza A virus.
Nguyen Thi Duy Nhat, Stacy Todd, Erwin de Bruin, Tran Thi Nhu Thao, Nguyen Ha Thao Vy, Tran Minh Quan, Dao Nguyen Vinh, Janko van Beek, Pham Hong Anh, Ha Minh Lam, Nguyen Thanh Hung, Nguyen Thi Le Thanh, Huynh Le Anh Huy, Vo Thi Hong Ha, Stephen Baker, Guy E Thwaites, Nguyen Thi Nam Lien, Tran Thi Kim Hong, Jeremy Farrar, Cameron P Simmons, Nguyen Van Vinh Chau, Marion Koopmans, Maciej F Boni
Apr 10, 2019
Seroepidemiological studies aim to understand population-level exposure and immunity to infectious diseases. Their results are normally presented as binary outcomes describing the presence or absence of pathogen-specific...
A Double-blind, Randomized, Placebo-controlled Trial of Lactobacillus acidophilus for the Treatment of Acute Watery Diarrhea in Vietnamese Children.
Tran Thi Hong Chau, Nguyen Ngoc Minh Chau, Nhat Thanh Hoang Le, Hao Chung The, Phat Voong Vinh, Nguyen Thi Nguyen To, Nguyen Minh Ngoc, Ha Manh Tuan, Tang Le Chau Ngoc, Marion-Eliette Kolader, Jeremy J Farrar, Marcel Wolbers, Guy E Thwaites, Stephen Baker, Oxford-Vietnam Probiotics Study Group
Aug 02, 2019
Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi
Pham Thanh Duy, Nga Tran Vu Thieu, To Nguyen Thi Nguyen, Ho Ngoc Dan Thanh, Sabina Dongol, Abhilasha Karkey, Megan Carey, Buddha Basnyat, Gordon Dougan, Maia A. Rabaa, Stephen Baker
Nov 02, 2020
Despite recent advances in typhoid fever control, asymptomatic carriage of Salmonella Typhi in the gallbladder remains poorly understood. Aiming to understand if S. Typhi becomes genetically adapted for long-term colonisation in...
A Model of Semantic-Based Image Retrieval Using C-Tree and Neighbor Graph
The problems of image mining and semantic image retrieval play an important role in many areas of life. In this paper, a semantic-based image retrieval system is proposed that relies on the combination of C-Tree, which was built...
Published by: IGI Global Scientific Publishing
Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi.
Pham Thanh Duy, Nga Tran Vu Thieu, To Nguyen Thi Nguyen, Ho Ngoc Dan Thanh, Sabina Dongol, Abhilasha Karkey, Megan Carey, Buddha Basnyat, Gordon Dougan, Maia A Rabaa, Stephen Baker
Oct 27, 2020
Despite recent advances in typhoid fever control, asymptomatic carriage of Salmonella Typhi in the gallbladder remains poorly understood. Aiming to understand if S. Typhi becomes genetically adapted for long-term colonisation in...
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