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Nancy Hinson Cox

Jan 01, 0001

In her July 16, 1974 interview with Ann Yarborough Evans, Nancy Cox recalls Winthrop customs from 1930-1934. This interview was conducted for inclusion into the Louise Pettus Archives and Special Collections Oral History Program.

Home economics teaching Dorm Life Rules and Regulations daisy chain blue line McLaurin Lancaster Swimming religion Oral History

Published by: Winthrop University

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Distinct features of dendritic cells and anti-Ig activated B cells as stimulators of the primary mixed leukocyte reaction

Joshua P. Metlay, Ellen Puré

Jan 01, 0001

Highly enriched populations of B lymphoblasts have been isolated after culture with anti-Ig-Sepharose and compared with dendritic cells as stimulators of CD4+ T cells in the murine MLR. The two populations clearly differed in...

B lymphocyte Cell culture dendritic cell mixed lymphocyte culture T lymphocyte

Published by: Rockefeller University

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Cancer Markers Selection Using Network-Based Cox Regression

Antonella Iuliano, Annalisa Occhipinti, Claudia Angelini, Italia De Feis, Pietro Lió

Mar 20, 2019

International initiatives such as the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) are collecting multiple datasets at different genome-scales with the aim of identifying novel cancer...

Cox model Cancer Gene Expression high-dimensionality Network regularization survival

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APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS.

Alba Signes, Raffaele Cerutti, Anna S Dickson, Cristiane Benincá, Elizabeth C Hinchy, Daniele Ghezzi, Rosalba Carrozzo, Enrico Bertini, Michael P Murphy, James A Nathan, Carlo Viscomi, Erika Fernandez-Vizarra, Massimo Zeviani

Dec 21, 2018

Loss-of-function mutations in APOPT1, a gene exclusively found in higher eukaryotes, cause a characteristic type of cavitating leukoencephalopathy associated with mitochondrial cytochrome c oxidase (COX) deficiency. Although the...

APOPT1‐COA8 cytochrome c oxidase mitochondrial encephalopathy proteasome–ubiquitin system Reactive Oxygen Species Animals Apoptosis Regulatory Proteins Cells Cultured Electron Transport Complex IV Genetic Complementation Test Humans Mice Mice Knockout Mitochondrial Proteins Protein Multimerization Reactive Oxygen Species Unfolded Protein Response

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Relaxing the independent censoring assumption in the Cox proportional hazards model using multiple imputation.

Dan Jackson, Ian R White, Shaun Seaman, Hannah Evans, Kathy Baisley, James Carpenter

Jun 14, 2018

The Cox proportional hazards model is frequently used in medical statistics. The standard methods for fitting this model rely on the assumption of independent censoring. Although this is sometimes plausible, we often wish to...

Schoenfeld residuals bootstrapping informative censoring Multiple imputation sensitivity analysis Survival Analysis Acyclovir Adolescent Adult Antiviral Agents Bias Biometry Computer Simulation Female HIV Infections Herpes Genitalis Herpesvirus 2 Human Humans Monte Carlo Method Proportional Hazards Models Randomized Controlled Trials as Topic Regression Analysis Tanzania Young Adult

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Going off grid

D. Simpson, Janine B. Illian, F. Lindgren, S. H. Sorbye, H. Rue

Mar 01, 2016

This paper introduces a new method for performing computational inference on log-Gaussian Cox processes. The likelihood is approximated directly by making novel use of a continuously specified Gaussian random field. We show that...

Approximation of Gaussian random fields Gaussian Markov random field Integrated nested Laplace approximation Spatial point process Stochastic partial differential equation

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On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale

Alexander M. G. Cox, Jan Obłój

Aug 01, 2015

We study the joint laws of a continuous, uniformly integrable martingale, its maximum, and its minimum. In particular, we give explicit martingale inequalities which provide upper and lower bounds on the joint exit probabilities...

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Going off grid

D. Simpson, Janine B. Illian, F. Lindgren, S. H. Sorbye, H. Rue

Mar 01, 2016

Approximation of Gaussian random fields Gaussian Markov random field Integrated nested Laplace approximation Spatial point process Stochastic partial differential equation

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On joint distributions of the maximum, minimum and terminal value of a continuous uniformly integrable martingale

Alexander M. G. Cox, Jan Obłój

Aug 01, 2015

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Martingale optimal transport with stopping

Erhan Bayraktar, Alexander M.G. Cox, Yavor Stoev

Jan 01, 0001

We solve the martingale optimal transport problem for cost functionals represented by optimal stopping problems. The measure-valued martingale approach developed in [A. M. G. Cox and S. Källblad, SIAM J. Control Optim., 55...

math.PR 60G40 93E20 91A10 91A60 60G07

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Martingale optimal transport with stopping

Erhan Bayraktar, Alexander M.G. Cox, Yavor Stoev

Jan 01, 0001

math.PR 60G40 93E20 91A10 91A60 60G07

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Robust Hedging of Options on a Leveraged Exchange Traded Fund

Alexander M. G. Cox, Sam M. Kinsley

Feb 01, 2019

A leveraged exchange traded fund (LETF) is an exchange traded fund that uses financial derivatives to amplify the price changes of a basket of goods. In this paper, we consider the robust hedging of European options on a...

Leveraged exchange traded fund monotonicity principle Optimal Skorokhod embedding problem Robust pricing and Hedging /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/1800/1804 name=Statistics, Probability and Uncertainty

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Robust Hedging of Options on a Leveraged Exchange Traded Fund

Alexander M. G. Cox, Sam M. Kinsley

Feb 01, 2019

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Discretisation and Duality of Optimal Skorokhod Embedding Problems

Alexander M. G. Cox, Sam M. Kinsley

Jul 31, 2018

We prove a strong duality result for a linear programming problem which has the interpretation of being a discretised optimal Skorokhod embedding problem, and we recover this continuous time problem as a limit of the discrete...

/dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics

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Discretisation and Duality of Optimal Skorokhod Embedding Problems

Alexander M. G. Cox, Sam M. Kinsley

Jul 31, 2018

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Cover Image for Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines.

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Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines.

Agata Tarczykowska, Niklas Engström, Darja Dobermann, Jonathan Powell, Nathalie Scheers

Apr 17, 2023

We previously showed that two iron compounds that are orally ingested by humans, namely ferric EDTA and ferric citrate, can induce an oncogenic growth factor (amphiregulin) in human intestinal epithelial adenocarcinoma cell...

Iron IL-6 IGF1R COX-2 amphiregulin IFNGR1 ferric pyrophosphate Cell Line Humans Adenocarcinoma Iron Compounds Ferric Compounds Salts Edetic Acid Interleukin-6 Iron Chelating Agents Signal Transduction STAT Transcription Factors Cyclooxygenase 2 Janus Kinases Biomarkers

Published by: International journal of molecular sciences

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Folding pathway of an Ig domain is conserved on and off the ribosome.

Pengfei Tian, Annette Steward, Renuka Kudva, Ting Su, Patrick J Shilling, Adrian A Nickson, Jeffrey J Hollins, Roland Beckmann, Gunnar von Heijne, Jane Clarke, Robert B Best

Dec 05, 2018

Proteins that fold cotranslationally may do so in a restricted configurational space, due to the volume occupied by the ribosome. How does this environment, coupled with the close proximity of the ribosome, affect the folding...

arrest peptide fraction folded kinetic model mechanical force molecular simulation Connectin Humans Kinetics Microfilament Proteins Models Molecular Protein Biosynthesis Protein Folding Ribosomes

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Cover Image for Evaluation of a worldwide EQA scheme for complex clonality analysis of clinical lymphoproliferative cases demonstrates a learning effect.

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Evaluation of a worldwide EQA scheme for complex clonality analysis of clinical lymphoproliferative cases demonstrates a learning effect.

Cleo Keppens, Elke Boone, Paula Gameiro, Véronique Tack, Elisabeth Moreau, Elizabeth Hodges, Paul Evans, Monika Brüggemann, Ian Carter, Dido Lenze, Maria Eugenia Sarasquete, Markus Möbs, Hongxiang Liu, Elisabeth MC Dequeker, Patricia JTA Groenen

Aug 14, 2021

Clonality analysis of immunoglobulin (IG) or T-cell receptor (TR) gene rearrangements is routine practice to assist diagnosis of lymphoid malignancies. Participation in external quality assessment (EQA) aids laboratories in...

Clonality analysis external quality assessment IG rearrangements TCR rearrangements Gene Rearrangement Genes Immunoglobulin Genes T-Cell Receptor Humans Laboratory Proficiency Testing Lymphoproliferative Disorders Molecular Diagnostic Techniques Observer Variation Polymerase Chain Reaction Predictive Value of Tests Quality Assurance Health Care Quality Control Reproducibility of Results

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Influence of offshore fringing reefs on infragravity period oscillations within a harbor

Junliang Gao, Xiaojun Zhou, Jun Zang, Qiang Chen, Li Zhou

Jun 15, 2018

The main objective of this paper is to systematically study the influence of offshore fringing reef topography on the infragravity-period harbor oscillations under the condition of wave breaking occurring over the reef. The...

Bound infragravity waves Free infragravity waves Fringing-reef topography Fully nonlinear Boussinesq models Harbor oscillations wave breaking /dk/atira/pure/subjectarea/asjc/2300/2305 name=Environmental Engineering /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering

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IGDB-2, an IG/FNIII Protein, Binds the ION Channel LGC-34 and Controls Sensory Compartment Morphogenesis in C. Elegans

Wendy Wang

Jan 01, 0001

Sensory organ glia surround neuronal receptive endings (NREs), forming a specialized extracellular space, or compartment, important for neuronal activity, and reminiscent of glia-ensheathed synapses in the central nervous...

Life Sciences

Published by: Rockefeller University

Cover Image for Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy.

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Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy.

Belinda M Kumpel, Radka Saldova, Carolien A M Koeleman, Jodie L Abrahams, Agnes Hipgrave Ederveen, Kathryn L Armour, Natalia I Olovnikova, Gestur Vidarsson, Rick Kapur, Pauline M Rudd, Manfred Wuhrer

Mar 02, 2020

Anti-D immunoglobulin (Anti-D Ig) prophylaxis prevents haemolytic disease of the fetus and newborn. Monoclonal IgG anti-Ds (mAb-Ds) would enable unlimited supplies but have differed in efficacy in FcγRIIIa-mediated ADCC assays...

Published by: Scientific reports

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Influence of offshore fringing reefs on infragravity period oscillations within a harbor

Junliang Gao, Xiaojun Zhou, Jun Zang, Qiang Chen, Li Zhou

Jun 15, 2018

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The geometry of multi-marginal Skorokhod Embedding

Mathias Beiglboeck, Alexander Cox, Martin Huesmann

Apr 30, 2020

The Skorokhod Embedding Problem is one of the classical problems in the theory of stochastic processes, with applications in many different fields [cf. the surveys (Hobson in: Paris-Princeton lectures on mathematical finance...

math.PR q-fin.PR 60G42 60G44 91G20

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Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy.

Belinda M Kumpel, Radka Saldova, Carolien AM Koeleman, Jodie L Abrahams, Agnes Hipgrave Ederveen, Kathryn L Armour, Natalia I Olovnikova, Gestur Vidarsson, Rick Kapur, Pauline M Rudd, Manfred Wuhrer

Jan 29, 2021