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Results: 328
Sensitization of colonic nociceptors by TNFα is dependent on TNFR1 expression and p38 MAPK activity.
Katie H Barker, James P Higham, Luke A Pattison, Toni S Taylor, Iain P Chessell, Fraser Welsh, Ewan St J Smith, David C Bulmer
Jul 22, 2022
Visceral pain is a leading cause of morbidity in gastrointestinal diseases, which is exacerbated by the gut-related side-effects of many analgesics. New treatments are needed and further understanding of the mediators and...
TRPV1 Capsaicin inflammatory bowel disease Irritable Bowel Syndrome nociception p38 MAPK tumour necrosis factor-alpha visceral pain Animals Capsaicin Ganglia Spinal Mice Nociceptors Receptors Tumor Necrosis Factor Type I TRPV Cation Channels Tumor Necrosis Factor-alpha visceral pain p38 Mitogen-Activated Protein Kinases
Deep and Frequent Phenotyping study protocol
Ivan Koychev, Jennifer Lawson, Tharani Chessell, Clare Mackay, Roger Gunn, Barbara Sahakian, James B Rowe, Alan J Thomas, Lynn Rochester, Dennis Chan, Brian Tom, Paresh Malhotra, Clive Ballard, Iain Chessell, Craig W Ritchie, Vanessa Raymont, Iracema Leroi, Imre Lengyel, Matt Murray, David L Thomas, John Gallacher, Simon Lovestone
Feb 11, 2019
Alzheimer’s disease Amyloid Biomarkers prodromal dementia Tau Aged Alzheimer Disease Amyloid beta-Peptides Biomarkers Case-Control Studies Cognition Disease Progression Female Gait analysis Humans Magnetic Resonance Imaging Male Mental Status and Dementia Tests Multicenter Studies as Topic Neuroimaging Observational Studies as Topic Phenotype Positron Emission Tomography Computed Tomography
Drones and global navigation satellite systems
Iain Sheridan
May 10, 2020
Aerial unmanned vehicles, so-called drones, present a paradigm shift away from the long-term use by scientists of manned aeroplanes and helicopters. This is evident from the number of research articles that focus on data...
Key Account Management
Iain Davies
Jan 12, 2014
Despite the prevalence of Key Account Management (KAM) in today’s business environment, there is a dearth of quality research investigating the mechanisms through which companies’ implement KAM and the likely success of the...
Published by: Key Account Management Best Practice Knowledge Share
The effectiveness of Key Account Management practices
This paper investigates the extent to which Key Account Management (KAM) programs are achieving a range of financial and non-financial measures of effectiveness for implementing companies. It investigates a wide range of KAM...
Integrating Hybridity and Business Model Theory in Sustainable Entrepreneurship
This paper investigates the means by which business model innovations help mitigate hybrid tensions in sustainable entrepreneurs. By integrating the sustainable business models, and hybrid entrepreneurship literature it...
business models Hybrid organizing Social enterprise social entrepreneurship sustainability Sustainable entrepreneurship /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2300/2300 name=General Environmental Science /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy /dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth
Fine asymptotics for the consistent maximal displacement of branching brownian motion
Matthew Iain Roberts
Mar 13, 2015
Ipt is well-known that the maximal particle in a branching Brownian motion sits near (Formula-Presented)log t at time t. One may then ask about the paths of particles near the frontier: how close can they stay to this...
Fine asymptotics for the consistent maximal displacement of branching brownian motion
Matthew Iain Roberts
Mar 13, 2015
Ipt is well-known that the maximal particle in a branching Brownian motion sits near (Formula-Presented)log t at time t. One may then ask about the paths of particles near the frontier: how close can they stay to this...
The effectiveness of Key Account Management practices
This paper investigates the extent to which Key Account Management (KAM) programs are achieving a range of financial and non-financial measures of effectiveness for implementing companies. It investigates a wide range of KAM...
Key Account Management
Iain Davies
Jan 12, 2014
Despite the prevalence of Key Account Management (KAM) in today’s business environment, there is a dearth of quality research investigating the mechanisms through which companies’ implement KAM and the likely success of the...
Published by: Key Account Management Best Practice Knowledge Share
Seeking sustainable futures in marketing and consumer research
Purpose Seeking ways towards a sustainable future is the most dominant socio-political challenge of our time. Marketing should have a crucial role to play in leading research and impact in sustainability, yet it is limited by...
The Role and Control of WNT Signalling in an HESC Model of Human Primitive Streak
Iain Martyn
Jan 01, 0001
In amniotes, gastrulation is marked by the creation of the primitive streak (PS) and is largely controlled by WNT, BMP, and ACTIVIN/NODAL signalling. Despite detailed characterization in model organisms, the human PS and the...
Published by: Rockefeller University
Consumer motivations for mainstream “ethical” consumption
Purpose: By looking at the motivation behind mainstream ethical consumption this paper explores why consumers absorb ethical habits into their daily consumption, despite having little interest or understanding of the ethics they...
What is ancestry?
Ancestry connects genetics and society in fundamental ways. For many people it has cultural, religious or even political significance, and can play a key role in shaping personal and public identities. People’s desire to...
Navigating <i>relative invariance</i>
The notion of relative invariance is highlighted as a foundational principle in how corporate heritage identity traits can remain the same, yet change in meaning over time. Yet, little is published regarding how this notion...
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