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Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation.
HHV-8 KSHV NK cell receptor ligands herpesvirus host cell restriction factors lytic reactivation Proteomics Viral immune evasion Antigens Differentiation T-Lymphocyte Cell Line DNA-Directed DNA Polymerase Down-Regulation Endothelial Cells Gene Library Gene Ontology Genes Viral Genetic Testing Herpesvirus 8 Human Humans immunomodulation Kinetics Ligands Mutation Proteome Proteomics Sarcoma Kaposi Up-Regulation Viral Proteins Virus Activation eIF-2 Kinase
A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection.
Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion.
Thomas WM Crozier, Edward JD Greenwood, James C Williamson, Wenrui Guo, Linsey M Porter, Ildar Gabaev, Ana Teixeira-Silva, Guinevere L Grice, Arthur Wickenhagen, Richard J Stanton, Eddie CY Wang, Sam J Wilson, Nicholas J Matheson, James A Nathan, Frank McCaughan, Paul J Lehner
Jan 08, 2023
Background: Quantitative proteomics is able to provide a comprehensive, unbiased description of changes to cells caused by viral infection, but interpretation may be complicated by differential changes in infected and uninfected...
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
Mar 06, 2023
Humans Membrane Proteins Protein Binding Spike Glycoprotein Coronavirus covid-19 Angiotensin-Converting Enzyme 2 SARS-CoV-2
Published by: PLoS biology
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
Jarrod Shilts, Thomas WM Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward JD Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
Feb 09, 2023
A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection.
ESA Voyage 2050 white paper
Paolo Soffitta, Niccolò Bucciantini, Eugene Churazov, Enrico Costa, Michal Dovciak, Hua Feng, Jeremy Heyl, Adam Ingram, Keith Jahoda, Philip Kaaret, Timothy Kallman, Vladimir Karas, Ildar Khabibullin, Henric Krawczynski, Julien Malzac, Frederic Marin, Herman Marshall, Giorgio Matt, Fabio Muleri, Carole Mundell, Mark Pearce, Pierre-Olivier Petrucci, Juri Poutanen, Roger Romani, Andrea Santangelo, Gianpiero Tagliaferri, Roberto Taverna, Roberto Turolla, Jacco Vink, Silvia Zane
Oct 22, 2019
Since the birth of X-ray Astronomy, spectacular advances have been seen in the imaging, spectroscopic and timing studies of the hot and violent X-ray Universe, and further leaps forward are expected in the future. On the other...
Published by: European Southern Observatory
ESA Voyage 2050 white paper
Paolo Soffitta, Niccolò Bucciantini, Eugene Churazov, Enrico Costa, Michal Dovciak, Hua Feng, Jeremy Heyl, Adam Ingram, Keith Jahoda, Philip Kaaret, Timothy Kallman, Vladimir Karas, Ildar Khabibullin, Henric Krawczynski, Julien Malzac, Frederic Marin, Herman Marshall, Giorgio Matt, Fabio Muleri, Carole Mundell, Mark Pearce, Pierre-Olivier Petrucci, Juri Poutanen, Roger Romani, Andrea Santangelo, Gianpiero Tagliaferri, Roberto Taverna, Roberto Turolla, Jacco Vink, Silvia Zane
Oct 22, 2019
Since the birth of X-ray Astronomy, spectacular advances have been seen in the imaging, spectroscopic and timing studies of the hot and violent X-ray Universe, and further leaps forward are expected in the future. On the other...
Published by: European Southern Observatory