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An Energy Harvester for Low-Frequency Electrical Signals
Xin Wang, Peter Wilson, Ricardo Leite, Guiyou Chen, Helena Freitas, Kamal Asadi, Edsger Smits, Ilias Katsouras, Paulo Rocha
Jun 05, 2020
Generating electricity from low-frequency mechanical agitations produced by ocean waves, plants, or human motion is emerging as a key, environmentally friendly technology in combating harmful emissions caused by burning...
An Energy Harvester for Low-Frequency Electrical Signals
Xin Wang, Peter Wilson, Ricardo Leite, Guiyou Chen, Helena Freitas, Kamal Asadi, Edsger Smits, Ilias Katsouras, Paulo Rocha
Jun 05, 2020
Generating electricity from low-frequency mechanical agitations produced by ocean waves, plants, or human motion is emerging as a key, environmentally friendly technology in combating harmful emissions caused by burning...
The Use of Autologous Chondrocyte and Mesenchymal Stem Cell Implants for the Treatment of Focal Chondral Defects in Human Knee Joints-A Systematic Review and Meta-Analysis.
Focal chondral defects of the knee occur commonly in the young, active population due to trauma. Damage can insidiously spread and lead to osteoarthritis with significant functional and socioeconomic consequences. Implants...
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts.
Ilias Georgakopoulos-Soares, Gene Koh, Sophie E Momen, Josef Jiricny, Martin Hemberg, Serena Nik-Zainal
Mar 31, 2020
Amino Acid Motifs Computational Biology DNA Breaks Double-Stranded DNA Mutational Analysis DNA Repair DNA Replication Gene Deletion Gene Expression Regulation Neoplastic genetic variation Genome Human Genomics Humans INDEL Mutation Mutagenesis Neoplasms Polynucleotides Repetitive Sequences Nucleic Acid Sequence Analysis RNA Transcription Genetic
Bone Marrow-Derived Mesenchymal Stem Cell Implants for the Treatment of Focal Chondral Defects of the Knee in Animal Models
Osteoarthritis remains an unfortunate long-term consequence of focal cartilage defects of the knee. Associated with functional loss and pain, it has necessitated the exploration of new therapies to regenerate cartilage before...
Regeneration Cartilage Scaffold Implant Bone marrow-derived mesenchymal stem cells Cartilage To Cartilage Integration Cartilage Articular Mesenchymal Stem Cells Bone Marrow Animals Humans Cartilage Diseases Mesenchymal Stem Cell Transplantation Tissue Engineering Tissue Scaffolds
Published by: International journal of molecular sciences
Bone Marrow-Derived Mesenchymal Stem Cell Implants for the Treatment of Focal Chondral Defects of the Knee in Animal Models
The Use of Autologous Chondrocyte and Mesenchymal Stem Cell Implants for the Treatment of Focal Chondral Defects in Human Knee Joints-A Systematic Review and Meta-Analysis.
Focal chondral defects of the knee occur commonly in the young, active population due to trauma. Damage can insidiously spread and lead to osteoarthritis with significant functional and socioeconomic consequences. Implants...
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts
Ilias Georgakopoulos-Soares, Gene Koh, Sophie E. Momen, Josef Jiricny, Martin Hemberg, Serena Nik-Zainal
Apr 24, 2021
Abstract: The mechanisms that underpin how insertions or deletions (indels) become fixed in DNA have primarily been ascribed to replication-related and/or double-strand break (DSB)-related processes. Here, we introduce a method...
State Capitalism and the New Global D/development Regime.
Official discourses of Development are being redefined. If the key geopolitical contexts shaping the post-war Development project were decolonisation and the Cold War, the defining world-historical transformations shaping the...
bulkAnalyseR
Bulk sequencing experiments (single- and multi-omics) are essential for exploring wide-ranging biological questions. To facilitate interactive, exploratory tasks, coupled with the sharing of easily accessible information, we...
The IHAT-GUT Iron Supplementation Trial in Rural Gambia
Isabella Stelle, Lorraine K McDonagh, Ilias Hossain, Anastasia Z Kalea, Dora Ia Pereira
Mar 31, 2021
INTRODUCTION: In most sub-Saharan African countries iron deficiency anaemia remains highly prevalent in children and this has not changed in the last 25 years. Supplementation with iron hydroxide adipate tartrate (IHAT) was...
anaemia clinical trial Global Health Iron Iron deficiency Iron deficiency anaemia low resource setting Malnutrition Micronutrients nutrition intervention Public Health Qualitative Anemia Iron-Deficiency Child Delivery of Health Care Dietary Supplements Double-Blind Method Ferric Compounds Focus Groups Gambia Humans Iron Dietary Poverty qualitative research Rural Population
Hemoglobin point-of-care testing in rural Gambia
BACKGROUND: Anemia is one of the most impactful nutrient deficiencies in the world and disproportionately affects children in low-resource settings. Point-of-care devices (PoCDs) measuring blood hemoglobin (Hb) are widely used...
Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation.
Dafni C Delivoria, Sean Chia, Johnny Habchi, Michele Perni, Ilias Matis, Nikoletta Papaevgeniou, Martin Reczko, Niki Chondrogianni, Christopher M Dobson, Michele Vendruscolo, Georgios Skretas
Dec 18, 2019
Protein misfolding and aggregation are associated with a many human disorders, including Alzheimer's and Parkinson's diseases. Toward increasing the effectiveness of early-stage drug discovery for these conditions, we report a...
MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development.
Guillermo E Parada, Roberto Munita, Ilias Georgakopoulos-Soares, Hugo JR Fernandes, Veronika R Kedlian, Emmanouil Metzakopian, Maria Estela Andres, Eric A Miska, Martin Hemberg
Mar 05, 2021
BACKGROUND: Microexons, exons that are ≤ 30 nucleotides, are a highly conserved and dynamically regulated set of cassette exons. They have key roles in nervous system development and function, as evidenced by recent results...
COVID-19 Vaccination Intent and Willingness to Pay in Bangladesh
Russell Kabir, Ilias Mahmud, Mohammad Tawfique Hossain Chowdhury, Divya Vinnakota, Shah Saif Jahan, Nazeeba Siddika, Samia Naz Isha, Sujan Kanti Nath, Ehsanul Hoque Apu
Apr 23, 2021
This article reports the intent to receive a SARS-COV-2 vaccine, its predictors and willingness to pay in Bangladesh. We carried out an online cross-sectional survey of 697 adults from the general population of Bangladesh in...
Regional Haemodynamic and Metabolic Coupling in Infants.
Maheen F Siddiqui, Paola Pinti, Sarah Lloyd-Fox, Emily JH Jones, Sabrina Brigadoi, Liam Collins-Jones, Ilias Tachtsidis, Mark H Johnson, Clare E Elwell
Feb 18, 2022
Metabolic pathways underlying brain function remain largely unexplored during neurodevelopment, predominantly due to the lack of feasible techniques for use with awake infants. Broadband near-infrared spectroscopy (bNIRS)...
Regional Haemodynamic and Metabolic Coupling in Infants.
Maheen F Siddiqui, Paola Pinti, Sarah Lloyd-Fox, Emily JH Jones, Sabrina Brigadoi, Liam Collins-Jones, Ilias Tachtsidis, Mark H Johnson, Clare E Elwell
Mar 28, 2022
Metabolic pathways underlying brain function remain largely unexplored during neurodevelopment, predominantly due to the lack of feasible techniques for use with awake infants. Broadband near-infrared spectroscopy (bNIRS)...
Alternative splicing modulation by G-quadruplexes.
Ilias Georgakopoulos-Soares, Guillermo E Parada, Hei Yuen Wong, Ragini Medhi, Giulia Furlan, Roberto Munita, Eric A Miska, Chun Kit Kwok, Martin Hemberg
Jun 07, 2022
Alternative splicing is central to metazoan gene regulation, but the regulatory mechanisms are incompletely understood. Here, we show that G-quadruplex (G4) motifs are enriched ~3-fold near splice junctions. The importance of...
MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development
Guillermo E. Parada, Roberto Munita, Ilias Georgakopoulos-Soares, Hugo J. R. Fernandes, Veronika R. Kedlian, Emmanouil Metzakopian, Maria Estela Andres, Eric A. Miska, Martin Hemberg
Jan 22, 2021
Abstract: Background: Microexons, exons that are ≤ 30 nucleotides, are a highly conserved and dynamically regulated set of cassette exons. They have key roles in nervous system development and function, as evidenced by recent...
A novel nano-iron supplement to safely combat iron deficiency and anaemia in young children
Dora Ia Pereira, Nuredin I Mohammed, Ogochukwu Ofordile, Famalang Camara, Bakary Baldeh, Thomas Mendy, Chilel Sanyang, Amadou T Jallow, Ilias Hossain, James Wason, Andrew M Prentice
Dec 17, 2018
Background: Iron deficiency and its associated anaemia (IDA) are the leading forms of micronutrient malnutrition worldwide. Here we describe the rationale and design of the first clinical trial evaluating the efficacy and safety...
Depression among the Non-Native International Undergraduate Students Studying Dentistry in Bangladesh.
Russell Kabir, Samia Naz Isha, Mohammad Tawfique Hossain Chowdhury, Nazeeba Siddika, Shah Saif Jahan, Arup Kumar Saha, Sujan Kanti Nath, Mohammed Shahed Jahan, Madhini Sivasubramanian, Ilias Mahmud, Ehsanul Hoque Apu
May 29, 2021
BACKGROUND: Bangladesh has been attracting international students with interests in various subjects recently. Every year students from different parts of the world come to study undergraduate and postgraduate courses, mostly at...
Isolation of neural stem and oligodendrocyte progenitor cells from the brain of live rats.
Freyja McClenahan, Christina Dimitriou, Christos Koutsakis, Dimitrios Dimitrakopoulos, Asterios Arampatzis, Paraskevi Kakouri, Michaela Kourla, Sofia Oikonomou, Evangelia Andreopoulou, Melina Patsonis, Danai-Kassandra Meri, Rana-Tahir Rasool, Robin Jm Franklin, Ilias Kazanis
Aug 25, 2021
Postnatal brain neural stem and progenitor cells (NSPCs) cluster in anatomically inaccessible stem cell niches, such as the subependymal zone (SEZ). Here, we describe a method for the isolation of NSPCs from live animals, which...
cerebrospinal fluid ependymal cell Liquid biopsy Neural Stem Cells Neuraminidase Neurogenesis oligodendrocyte progenitor cells Stem Cell Niche subependymal zone Ventricular-subventricular zone Animals Brain Cell Culture Techniques Cell Differentiation cerebrospinal fluid Corpus Callosum Humans Liquid biopsy Male Neural Stem Cells oligodendrocyte precursor cells Rats Rats Long-Evans Rats Sprague-Dawley Rats Wistar Stem Cell Niche
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