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The search for a sustainable alternative to slash-and-burn agriculture in the World's rain forests
Michael Hands
Jun 11, 2021
This account describes the context, history and outcomes of a series of studies into the ecology of slash-and-burn (S-B) agriculture in the world's humid tropics. These studies, which began in the mid-1980s, identified promising...
Methods of Working With Local Digital Resources on History
This study aimed to identify the best techniques and approaches to working with digital resources on history suitable for both scientific research and teaching. The methodological basis of this study was the author’s methodology...
Published by: IGI Global Scientific Publishing
Linear and nonlinear convection in porous media between coaxial cylinders
We uncover novel features of three-dimensional natural convection in porous media by investigating convection in an annular porous cavity contained between two vertical coaxial cylinders. The investigations are made using a...
Linear and nonlinear convection in porous media between coaxial cylinders
We uncover novel features of three-dimensional natural convection in porous media by investigating convection in an annular porous cavity contained between two vertical coaxial cylinders. The investigations are made using a...
Parasitic infections and resource economy of Danish Iron Age settlement through ancient DNA sequencing.
Katrine Wegener Tams, Martin Jensen Søe, Inga Merkyte, Frederik Valeur Seersholm, Peter Steen Henriksen, Susanne Klingenberg, Eske Willerslev, Kurt H Kjær, Anders Johannes Hansen, Christian Moliin Outzen Kapel
Sep 11, 2018
In this study, we screen archaeological soil samples by microscopy and analyse the samples by next generation sequencing to obtain results with parasites at species level and untargeted findings of plant and animal DNA. Three...
Allelic series of Huntington's disease knock-in mice reveals expression discorrelates.
Ashish Kumar, Jennifer Zhang, Sara Tallaksen-Greene, Michael R Crowley, David K Crossman, A Jennifer Morton, Thomas Van Groen, Inga Kadish, Roger L Albin, Mathieu Lesort, Peter J Detloff
Mar 21, 2016
Penetrance estimates for BRCA1, BRCA2 (also applied to Lynch syndrome) based on presymptomatic testing
D Gareth Evans, Emma Woodward, Elaine F Harkness, Anthony Howell, Inga Plaskocinska, Eamonn R Maher, Marc D Tischkowitz, Fiona Lalloo
Jul 02, 2018
PURPOSE: The identification of BRCA1, BRCA2 or mismatch repair (MMR) pathogenic gene variants in familial breast/ovarian/colorectal cancer families facilitates predictive genetic testing of at-risk relatives. However...
Lynch syndrome BRCA1 BRCA2 Penetrance pre-symptomatic Adult Aged BRCA1 Protein BRCA2 Protein Bayes Theorem Breast Neoplasms Colorectal Neoplasms Hereditary Nonpolyposis Female Genetic Predisposition to Disease Genetic Testing Humans Male Middle Aged MutL Protein Homolog 1 MutS Homolog 2 Protein Mutation Ovarian Neoplasms Penetrance Risk Assessment
Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors.
Inga H Rye, Anne Trinh, Anna B Saetersdal, Daniel Nebdal, Ole Christian Lingjaerde, Vanessa Almendro, Kornelia Polyak, Anne-Lise Børresen-Dale, Åslaug Helland, Florian Markowetz, Hege G Russnes
Mar 04, 2019
Targeted therapy for patients with HER2-positive (HER2+) breast cancer has improved overall survival, but many patients still suffer relapse and death from the disease. Intratumor heterogeneity of both estrogen receptor (ER) and...
Targeted transcriptomics reveals signatures of large-scale independent origins and concerted regulation of effector genes in Radopholus similis.
Paulo Vieira, Roxana Y Myers, Clement Pellegrin, Catherine Wram, Cedar Hesse, Thomas R Maier, Jonathan Shao, Georgios D Koutsovoulos, Inga Zasada, Tracie Matsumoto, Etienne GJ Danchin, Thomas J Baum, Sebastian Eves-van den Akker, Lev G Nemchinov
Nov 22, 2021
The burrowing nematode, Radopholus similis, is an economically important plant-parasitic nematode that inflicts damage and yield loss to a wide range of crops. This migratory endoparasite is widely distributed in warmer regions...
Confirmation of TACO1 as a Leigh Syndrome Disease Gene in Two Additional Families.
Yavuz Oktay, Serdal Güngör, Lena Zeltner, Sarah Wiethoff, Ludger Schöls, Ece Sonmezler, Elmasnur Yilmaz, Benjamin Munro, Benjamin Bender, Christoph Kernstock, Sofie Kaemereit, Inga Liepelt, Ana Töpf, Uluc Yis, Steven Laurie, Ahmet Yaramis, Stephan Zuchner, Semra Hiz, Hanns Lochmüller, Rebecca Schüle, Rita Horvath
Apr 29, 2020
Thymidine Metabolism as Confounding Factor of 3'-Deoxy-3'-[18F]Fluorothymidine Uptake after Therapy in a Colorectal Cancer Model.
Sonja Schelhaas, Lydia Wachsmuth, Sven Hermann, Natascha Rieder, Astrid Heller, Kathrin Heinzmann, Davina J Honess, Donna-Michelle Smith, Inga B Fricke, Nathalie Just, Sabrina Doblas, Ralph Sinkus, Christian Döring, Klaus Peter Schäfers, John R Griffiths, Cornelius Faber, Richard Schneider, Eric Ofori Aboagye, Andreas Hans Jacobs
Jun 11, 2018
Non-invasive monitoring of tumor therapy response helps in developing personalized treatment strategies. Here, we performed sequential positron emission tomography (PET) and diffusion-weighted magnetic resonance imaging (DW-MRI)...
Targeted transcriptomics reveals signatures of large-scale independent origins and concerted regulation of effector genes in Radopholus similis.
Paulo Vieira, Roxana Y Myers, Clement Pellegrin, Catherine Wram, Cedar Hesse, Thomas R Maier, Jonathan Shao, Georgios D Koutsovoulos, Inga Zasada, Tracie Matsumoto, Etienne GJ Danchin, Thomas J Baum, Sebastian Eves-van den Akker, Lev G Nemchinov
Jan 07, 2022
The burrowing nematode, Radopholus similis, is an economically important plant-parasitic nematode that inflicts damage and yield loss to a wide range of crops. This migratory endoparasite is widely distributed in warmer regions...
Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions
Gytis Dudas, Samuel L. Hong, Barney I. Potter, Sébastien Calvignac-Spencer, Frédéric S. Niatou-Singa, Thais B. Tombolomako, Terence Fuh-Neba, Ulrich Vickos, Markus Ulrich, Fabian H. Leendertz, Kamran Khan, Carmen Huber, Alexander Watts, Ingrida Olendraitė, Joost Snijder, Kim N. Wijnant, Alexandre M.J.J. Bonvin, Pascale Martres, Sylvie Behillil, Ahidjo Ayouba, Martin Foudi Maidadi, Dowbiss Meta Djomsi, Celestin Godwe, Christelle Butel, Aistis Šimaitis, Miglė Gabrielaitė, Monika Katėnaitė, Rimvydas Norvilas, Ligita Raugaitė, Giscard Wilfried Koyaweda, Jephté Kaleb Kandou, Rimvydas Jonikas, Inga Nasvytienė, Živilė Žemeckienė, Dovydas Gečys, Kamilė Tamušauskaitė, Milda Norkienė, Emilija Vasiliūnaitė, Danguolė Žiogienė, Albertas Timinskas, Marius Šukys, Mantas Šarauskas, Gediminas Alzbutas, Adrienne Amuri Aziza, Eddy Kinganda Lusamaki, Jean-Claude Makangara Cigolo, Francisca Muyembe Mawete, Emmanuel Lokilo Lofiko, Placide Mbala Kingebeni, Jean-Jacques Muyembe Tamfum, Marie Roseline Darnycka Belizaire, René Ghislain Essomba, Marie Claire Okomo Assoumou, Akenji Blaise Mboringong, Alle Baba Dieng, Dovilė Juozapaitė, Salome Hosch, Justino Obama, Mitoha Ondo’o Ayekaba, Daniel Naumovas, Arnoldas Pautienius, Clotaire Donatien Rafaï, Astra Vitkauskienė, Rasa Ugenskienė, Alma Gedvilaitė, Darius Čereškevičius, Vaiva Lesauskaitė, Lukas Žemaitis, Laimonas Griškevičius, Guy Baele
Oct 01, 2021
Abstract: Distinct SARS-CoV-2 lineages, discovered through various genomic surveillance initiatives, have emerged during the pandemic following unprecedented reductions in worldwide human mobility. We here describe a SARS-CoV-2...
SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70
Sara Gomes, Bartolomeo Bosco, Joana B Loureiro, Helena Ramos, Liliana Raimundo, Joana Soares, Nair Nazareth, Valentina Barcherini, Lucília Domingues, Carla Oliveira, Alessandra Bisio, Silvano Piazza, Matthias R Bauer, João P Brás, Maria Inês Almeida, Célia Gomes, Flávio Reis, Alan R Fersht, Alberto Inga, Maria MM Santos, Lucília Saraiva
Oct 28, 2019
Half of human cancers harbor TP53 mutations that render p53 inactive as a tumor suppressor. In these cancers, reactivation of mutant p53 (mutp53) through restoration of wild-type-like function constitutes a valuable anticancer...
Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America.
Roxana Zamudio, Patrick Boerlin, Racha Beyrouthy, Jean-Yves Madec, Stefan Schwarz, Michael R Mulvey, George G Zhanel, Ashley Cormier, Gabhan Chalmers, Richard Bonnet, Marisa Haenni, Inga Eichhorn, Heike Kaspar, Raquel Garcia-Fierro, James LN Wood, Alison E Mather
Dec 12, 2022
The impact of political objectives on optimal electricity generation and transmission in the Southern African Power Pool
Southern Africa’s electrification is at odds with United Nations goals to provide modern energy for all by 2030. Electricity planning, a crucial tool to optimally match future supply and demand, has largely focused on minimising...
The impact of political objectives on optimal electricity generation and transmission in the Southern African Power Pool
Southern Africa’s electrification is at odds with United Nations goals to provide modern energy for all by 2030. Electricity planning, a crucial tool to optimally match future supply and demand, has largely focused on minimising...
Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension.
Anna Ulrich, Pablo Otero-Núñez, John Wharton, Emilia M Swietlik, Stefan Gräf, Nicholas W Morrell, Dennis Wang, Allan Lawrie, Martin R Wilkins, Inga Prokopenko, Christopher J Rhodes, On Behalf Of The Nihr BioResource-Rare Diseases Consortium, UK PAH Cohort Study Consortium
Jan 08, 2021
Expression quantitative trait loci (eQTL) can provide a link between disease susceptibility variants discovered by genetic association studies and biology. To date, eQTL mapping studies have been primarily conducted in healthy...
Blood eQTL expression quantitative trait locus Genetics pulmonary arterial hypertension Base Sequence Familial Primary Pulmonary Hypertension Female Genetic Association Studies Genetic Predisposition to Disease Genome Genome-Wide Association Study Humans Male Polymorphism Single Nucleotide pulmonary arterial hypertension Quantitative Trait Loci Sequence Analysis RNA Transcriptome
Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension
Anna Ulrich, Pablo Otero-Núñez, John Wharton, Emilia M. Swietlik, Stefan Gräf, Nicholas W. Morrell, Dennis Wang, Allan Lawrie, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes, on behalf of The NIHR BioResource—Rare Diseases Consortium, UK PAH Cohort Study Consortium
Oct 23, 2020
Expression quantitative trait loci (eQTL) can provide a link between disease susceptibility variants discovered by genetic association studies and biology. To date, eQTL mapping studies have been primarily conducted in healthy...
An international cross-sectional investigation on social media, fitspiration content exposure, and related risks during the COVID-19 self-isolation period.
Ilaria Cataldo, Julius Burkauskas, Artemisa R Dores, Irene P Carvalho, Pierluigi Simonato, Ilaria De Luca, Maria Ángeles Gómez-Martínez, Alejandra Rebeca Melero Ventola, Zsolt Demetrovics, Attila Szabo, Krisztina Edina Ábel, Mami Shibata, Kei Kobayashi, Hironobu Fujiwara, Eva Maria Arroyo-Anlló, Giovanni Martinotti, Fernando Barbosa, Inga Griskova-Bulanova, Aiste Pranckeviciene, Henrietta Bowden-Jones, Gianluca Esposito, Ornella Corazza
Mar 02, 2022
With the global COVID-19 pandemic, governments from many countries in the world implemented various restrictions to prevent the SARS-Cov-2 virus's spread, including social distancing measures, quarantine, in-home lockdown, and...
Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice.
Inga Hofmann, Mitchell J Geer, Timo Vögtle, Andrew Crispin, Dean R Campagna, Alastair Barr, Monica L Calicchio, Silke Heising, Johanna P van Geffen, Marijke JE Kuijpers, Johan WM Heemskerk, Johannes A Eble, Klaus Schmitz-Abe, Esther A Obeng, Michael Douglas, Kathleen Freson, Corinne Pondarré, Rémi Favier, Gavin E Jarvis, Kyriacos Markianos, Ernest Turro, Willem H Ouwehand, Alexandra Mazharian, Mark D Fleming, Yotis A Senis
Oct 10, 2018
Unlike primary myelofibrosis (PMF) in adults, myelofibrosis in children is rare. Congenital (inherited) forms of myelofibrosis (cMF) have been described, but the underlying genetic mechanisms remain elusive. Here we describe 4...
Online Behaviours during the COVID-19 Pandemic and Their Associations with Psychological Factors
Julius Burkauskas, Naomi A Fineberg, Konstantinos Ioannidis, Samuel R Chamberlain, Henrietta Bowden-Jones, Inga Griskova-Bulanova, Aiste Pranckeviciene, Artemisa R Dores, Irene P Carvalho, Fernando Barbosa, Pierluigi Simonato, Ilaria De Luca, Rosin Mooney, Maria Ángeles Gómez-Martínez, Zsolt Demetrovics, Krisztina Edina Ábel, Attila Szabo, Hironobu Fujiwara, Mami Shibata, Alejandra R Melero-Ventola, Eva M Arroyo-Anlló, Ricardo M Santos-Labrador, Kei Kobayashi, Francesco Di Carlo, Cristina Monteiro, Giovanni Martinotti, Ornella Corazza
Sep 02, 2022
This cross-sectional study aimed to explore specific online behaviours and their association with a range of underlying psychological and other behavioural factors during the COVID-19 pandemic. Eight countries (Italy, Spain, the...
Exercise and Use of Enhancement Drugs at the Time of the COVID-19 Pandemic
Artemisa R Dores, Irene P Carvalho, Julius Burkauskas, Pierluigi Simonato, Ilaria De Luca, Roisin Mooney, Konstantinos Ioannidis, M Ángeles Gómez-Martínez, Zsolt Demetrovics, Krisztina Edina Ábel, Attila Szabo, Hironobu Fujiwara, Mami Shibata, Alejandra Rebeca Melero Ventola, Eva Maria Arroyo-Anlló, Ricardo M Santos-Labrador, Inga Griskova-Bulanova, Aiste Pranckeviciene, Kei Kobayashi, Giovanni Martinotti, Naomi A Fineberg, Fernando Barbosa, Ornella Corazza
Mar 24, 2021
Introduction: Little is known about the impact of restrictive measures during the COVID-19 pandemic on self-image and engagement in exercise and other coping strategies alongside the use of image and performance-enhancing drugs...
Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions.
Gytis Dudas, Samuel L Hong, Barney I Potter, Sébastien Calvignac-Spencer, Frédéric S Niatou-Singa, Thais B Tombolomako, Terence Fuh-Neba, Ulrich Vickos, Markus Ulrich, Fabian H Leendertz, Kamran Khan, Carmen Huber, Alexander Watts, Ingrida Olendraitė, Joost Snijder, Kim N Wijnant, Alexandre MJJ Bonvin, Pascale Martres, Sylvie Behillil, Ahidjo Ayouba, Martin Foudi Maidadi, Dowbiss Meta Djomsi, Celestin Godwe, Christelle Butel, Aistis Šimaitis, Miglė Gabrielaitė, Monika Katėnaitė, Rimvydas Norvilas, Ligita Raugaitė, Giscard Wilfried Koyaweda, Jephté Kaleb Kandou, Rimvydas Jonikas, Inga Nasvytienė, Živilė Žemeckienė, Dovydas Gečys, Kamilė Tamušauskaitė, Milda Norkienė, Emilija Vasiliūnaitė, Danguolė Žiogienė, Albertas Timinskas, Marius Šukys, Mantas Šarauskas, Gediminas Alzbutas, Adrienne Amuri Aziza, Eddy Kinganda Lusamaki, Jean-Claude Makangara Cigolo, Francisca Muyembe Mawete, Emmanuel Lokilo Lofiko, Placide Mbala Kingebeni, Jean-Jacques Muyembe Tamfum, Marie Roseline Darnycka Belizaire, René Ghislain Essomba, Marie Claire Okomo Assoumou, Akenji Blaise Mboringong, Alle Baba Dieng, Dovilė Juozapaitė, Salome Hosch, Justino Obama, Mitoha Ondo'o Ayekaba, Daniel Naumovas, Arnoldas Pautienius, Clotaire Donatien Rafaï, Astra Vitkauskienė, Rasa Ugenskienė, Alma Gedvilaitė, Darius Čereškevičius, Vaiva Lesauskaitė, Lukas Žemaitis, Laimonas Griškevičius, Guy Baele
Nov 02, 2021
Distinct SARS-CoV-2 lineages, discovered through various genomic surveillance initiatives, have emerged during the pandemic following unprecedented reductions in worldwide human mobility. We here describe a SARS-CoV-2 lineage -...
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