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Results: 241
Breaching the Barrier
The double-membrane cell envelope of Gram-negative bacteria is a sophisticated barrier that facilitates the uptake of nutrients and protects the organism from toxic compounds. An antibiotic molecule must find its way through the...
antibiotic resistance efflux envelope permeability OUTER-MEMBRANE PROTEINS Porins Anti-Bacterial Agents Bacterial Outer Membrane Bacterial Outer Membrane Proteins Biological Transport Cell Membrane Permeability Electrophysiology Gram-Negative Bacteria Hydrophobic and Hydrophilic Interactions Lipopolysaccharides Liposomes Microscopy Models Molecular Permeability Porins
Vocalic Intrusions in Consonant Clusters in Child-Directed vs. Adult-Directed Speech.
Nina Gram Garmann, Pernille Hansen, Hanne Gram Simonsen, Elisabeth Holm, Eirik Tengesdal, Brechtje Post, Elinor Payne
Sep 05, 2021
In this paper, we investigate a prosodic-phonetic feature in child-directed speech within a dynamic, complex, interactive theoretical framework. We focus on vocalic intrusions, commonly occurring in Norwegian word initial...
Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria
SIGNR1, a member of a new family of mouse C-type lectins, is expressed at high levels in macrophages (M?) within the splenic marginal zone, lymph node medulla, and in some strains, in peritoneal cavity. We previously reported...
Published by: Rockefeller University
Vocalic Intrusions in Consonant Clusters in Child-Directed vs. Adult-Directed Speech
Nina Gram Garmann, Pernille Hansen, Hanne Gram Simonsen, Elisabeth Holm, Eirik Tengesdal, Brechtje Post, Elinor Payne
Aug 02, 2021
In this paper, we investigate a prosodic-phonetic feature in child-directed speech within a dynamic, complex, interactive theoretical framework. We focus on vocalic intrusions, commonly occurring in Norwegian word initial...
Multicountry Distribution and Characterization of Extended-spectrum β-Lactamase-associated Gram-negative Bacteria From Bloodstream Infections in Sub-Saharan Africa.
Trevor Toy, Gi Deok Pak, Trung Pham Duc, James I Campbell, Muna Ahmed El Tayeb, Vera von Kalckreuth, Justin Im, Ursula Panzner, Ligia Maria Cruz Espinoza, Daniel Eibach, Denise Myriam Dekker, Se Eun Park, Hyon Jin Jeon, Frank Konings, Ondari D Mogeni, Leonard Cosmas, Morten Bjerregaard-Andersen, Nagla Gasmelseed, Julian T Hertz, Anna Jaeger, Ralf Krumkamp, Benedikt Ley, Kamala Thriemer, Leon Parfait Kabore, Aissatou Niang, Tiana Mirana Raminosoa, Emmanuel Sampo, Nimako Sarpong, Abdramane Soura, Ellis Owusu-Dabo, Mekonnen Teferi, Biruk Yeshitela, Sven Poppert, Jürgen May, Jerome H Kim, Yun Chon, Jin Kyung Park, Abroaham Aseffa, Robert F Breiman, Heidi Schütt-Gerowitt, Peter Aaby, Yaw Adu-Sarkodie, John A Crump, Raphaël Rakotozandrindrainy, Christian G Meyer, Amy Gassama Sow, John D Clemens, Thomas F Wierzba, Stephen Baker, Florian Marks
Nov 26, 2019
BACKGROUND: Antimicrobial resistance (AMR) is a major global health concern, yet, there are noticeable gaps in AMR surveillance data in regions such as sub-Saharan Africa. We aimed to measure the prevalence of extended-spectrum...
Africa ESBL antibiotic resistance Antimicrobial resistance Extended-spectrum β-lactamase SURVEILLANCE Adolescent Adult Africa South of the Sahara Anti-Bacterial Agents Child Child Preschool Drug Resistance Multiple Bacterial Gram-Negative Bacteria Gram-Negative Bacterial Infections Humans Infant Infant Newborn Microbial Sensitivity Tests Middle Aged prevalence sentinel surveillance Young Adult beta-Lactamases
Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status
Rebecca Ritte, Annekatrin Lukanova, Franco Berrino, Laure Dossus, Anne Tjønneland, Anja Olsen, Thure Filskov Overvad, Kim Overvad, Françoise Clavel-Chapelon, Agnès Fournier, Guy Fagherazzi, Sabine Rohrmann, Birgit Teucher, Heiner Boeing, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Sabina Sieri, Salvatore Panico, Rosario Tumino, Paolo Vineis, José Ramón Quirós, Genevieve Buckland, Maria-José Sánchez, Pilar Amiano, María-Dolores Chirlaque, Eva Ardanaz, Malin Sund, Per Lenner, Bas Bueno-de-Mesquita, Carla H van Gils, Petra Hm Peeters, Sanda Krum-Hansen, Inger Torhild Gram, Eiliv Lund, Kay-Tee Khaw, Nick Wareham, Naomi E Allen, Timothy J Key, Isabelle Romieu, Sabina Rinaldi, Afshan Siddiq, David Cox, Elio Riboli, Rudolf Kaaks
Jun 04, 2012
A flavin-based extracellular electron transfer mechanism in diverse Gram-positive bacteria.
Samuel H Light, Lin Su, Rafael Rivera-Lugo, Jose A Cornejo, Alexander Louie, Anthony T Iavarone, Caroline M Ajo-Franklin, Daniel A Portnoy
Jun 07, 2021
Extracellular electron transfer (EET) describes microbial bioelectrochemical processes in which electrons are transferred from the cytosol to the exterior of the cell1. Mineral-respiring bacteria use elaborate haem-based...
Lifetime and baseline alcohol intakes and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition study.
Sabine Naudin, Kuanrong Li, Tristan Jaouen, Nada Assi, Cecilie Kyrø, Anne Tjønneland, Kim Overvad, Marie-Christine Boutron-Ruault, Vinciane Rebours, Anne-Laure Védié, Heiner Boeing, Rudolf Kaaks, Verena Katzke, Christina Bamia, Androniki Naska, Antonia Trichopoulou, Franco Berrino, Giovanna Tagliabue, Domenico Palli, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Petra H Peeters, HB As Bueno-de-Mesquita, Elisabete Weiderpass, Inger Torhild Gram, Guri Skeie, Maria-Dolores Chirlaque, Miguel Rodríguez-Barranco, Aurelio Barricarte, Jose Ramón Quirós, Miren Dorronsoro, Ingegerd Johansson, Malin Sund, Hanna Sternby, Kathryn E Bradbury, Nick Wareham, Elio Riboli, Marc Gunter, Paul Brennan, Eric J Duell, Pietro Ferrari
Jun 12, 2018
Recent evidence suggested a weak relationship between alcohol consumption and pancreatic cancer (PC) risk. In our study, the association between lifetime and baseline alcohol intakes and the risk of PC was evaluated, including...
MQVC
Extensive research efforts in the area of Information Retrieval were concentrated on developing retrieval systems related to Arabic language for the different natural language and information retrieval methodologies. However...
Published by: Digital Commons @ Texas A&M University-San Antonio
Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models
Renée T Fortner, Allison F Vitonis, Helena Schock, Anika Hüsing, Theron Johnson, Raina N Fichorova, Titilayo Fashemi, Hidemi S Yamamoto, Anne Tjønneland, Louise Hansen, Kim Overvad, Marie-Christine Boutron-Ruault, Marina Kvaskoff, Gianluca Severi, Heiner Boeing, Antonia Trichopoulou, Vassiliki Benetou, Carlo La Vecchia, Domenico Palli, Sabina Sieri, Rosario Tumino, Giuseppe Matullo, Amalia Mattiello, N Charlotte Onland-Moret, Petra H Peeters, Elisabete Weiderpass, Inger Torhild Gram, Mie Jareid, J Ramón Quirós, Eric J Duell, Maria-Jose Sánchez, María Dolores Chirlaque, Eva Ardanaz, Nerea Larrañaga, Björn Nodin, Jenny Brändstedt, Annika Idahl, Kay-Tee Khaw, Naomi Allen, Marc Gunter, Mattias Johansson, Laure Dossus, Melissa A Merritt, Elio Riboli, Daniel W Cramer, Rudolf Kaaks, Kathryn L Terry
May 05, 2017
BACKGROUND: Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening. METHODS: We evaluated cross-sectional relationships between lifestyle and...
Parental Report via a Mobile App in the Context of Early Language Trajectories
Karolina Mieszkowska, Grzegorz Krajewski, Krzysztof Sobota, Agnieszka Dynak, Joanna Kolak, Magdalena Krysztofiak, Barbara Łukomska, Magdalena Łuniewska, Nina Gram Garmann, Pernille Hansen, Anna Sara Hexeberg Romøren, Hanne Gram Simonsen, Katie Alcock, Napoleon Katsos, Ewa Haman
Apr 10, 2022
Social sciences researchers emphasize that new technologies can overcome the limitations of small and homogenous samples. In research on early language development, which often uses parental reports, taking the testing online...
Active Image-Assisted Food Records in Comparison to Regular Food Records
Overreporting of dietary intake in infants is a problem when using food records (FR), distorting possible relationships between diet and health outcomes. Image-assisted dietary assessment may improve the accuracy, but to date...
MQVC
Extensive research efforts in the area of Information Retrieval were concentrated on developing retrieval systems related to Arabic language for the different natural language and information retrieval methodologies. However...
Published by: Digital Commons @ Texas A&M University-San Antonio
MQVC
Extensive research efforts in the area of Information Retrieval were concentrated on developing retrieval systems related to Arabic language for the different natural language and information retrieval methodologies. However...
Published by: Digital Commons @ Texas A&M University-San Antonio
Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures.
Jennifer Stone, Deborah J Thompson, Isabel Dos Santos Silva, Christopher Scott, Rulla M Tamimi, Sara Lindstrom, Peter Kraft, Aditi Hazra, Jingmei Li, Louise Eriksson, Kamila Czene, Per Hall, Matt Jensen, Julie Cunningham, Janet E Olson, Kristen Purrington, Fergus J Couch, Judith Brown, Jean Leyland, Ruth Ml Warren, Robert N Luben, Kay-Tee Khaw, Paula Smith, Nicholas J Wareham, Sebastian M Jud, Katharina Heusinger, Matthias W Beckmann, Julie A Douglas, Kaanan P Shah, Heang-Ping Chan, Mark A Helvie, Loic Le Marchand, Laurence N Kolonel, Christy Woolcott, Gertraud Maskarinec, Christopher Haiman, Graham G Giles, Laura Baglietto, Kavitha Krishnan, Melissa C Southey, Carmel Apicella, Irene L Andrulis, Julia A Knight, Giske Ursin, Grethe I Grenaker Alnaes, Vessela N Kristensen, Anne-Lise Borresen-Dale, Inger Torhild Gram, Manjeet K Bolla, Qin Wang, Kyriaki Michailidou, Joe Dennis, Jacques Simard, Paul Pharoah, Alison M Dunning, Douglas F Easton, Peter A Fasching, V Shane Pankratz, John L Hopper, Celine M Vachon
May 20, 2015
Regulation of Surface Proteins Assembly on the Wall of Gram-Positive Bacteria
Assaf Raz
Jan 01, 0001
Cell wall peptidoglycan-anchored surface proteins are essential virulence factors in many Gram-positive bacteria. Attachment of these proteins to the peptidoglycan is achieved through a transpeptidation reaction, whereby sortase...
streptococcal disease Gram-Positive Bacteria surface proteins sortase localization protein anchoring sub-surface antigens LPXTGase Life Sciences
Published by: Rockefeller University
A high prevalence of multi-drug resistant Gram-negative bacilli in a Nepali tertiary care hospital and associated widespread distribution of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-encoding genes.
Sulochana Manandhar, Raphael M Zellweger, Nhukesh Maharjan, Sabina Dongol, Krishna G Prajapati, Guy Thwaites, Buddha Basnyat, Sameer Mani Dixit, Stephen Baker, Abhilasha Karkey
Jan 11, 2021
BACKGROUND: Multi-drug resistance (MDR) and extensive-drug resistance (XDR) associated with extended-spectrum beta-lactamases (ESBLs) and carbapenemases in Gram-negative bacteria are global public health concerns. Data on...
Antimicrobial resistance Carbapenemase ESBL ESKAPE Gram-negative bacilli multi-drug resistance Nepal Acinetobacter Anti-Bacterial Agents Bacterial Proteins Drug Resistance Multiple Bacterial Enterobacter Escherichia coli Gram-Negative Bacteria Gram-Negative Bacterial Infections Humans Klebsiella Microbial Sensitivity Tests Nepal prevalence Retrospective Studies Tertiary Care Centers beta-Lactamases
The Antibiotic resistance profiles of bacterial strains isolated from inpatients and outpatients from five hospitals in Egypt
Lamees galal1, Mosaad sayed Mohamed2, Riham Shawky3, Neveen AbdelAziz4*and Ramadan Eldomany3
Mar 11, 2015
Background:Multidrug resistance (MDR) of pathogens has become a serious threat for modern human health care. The strategy for the control of antimicrobial resistance lies mainly in the implementation of effective infection...
Published by: IJHS Medical Association
A high prevalence of multi-drug resistant Gram-negative bacilli in a Nepali tertiary care hospital and associated widespread distribution of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-encoding genes
Sulochana Manandhar, Raphael M. Zellweger, Nhukesh Maharjan, Sabina Dongol, Krishna G. Prajapati, Guy Thwaites, Buddha Basnyat, Sameer Mani Dixit, Stephen Baker, Abhilasha Karkey
Oct 21, 2020
Abstract: Background: Multi-drug resistance (MDR) and extensive-drug resistance (XDR) associated with extended-spectrum beta-lactamases (ESBLs) and carbapenemases in Gram-negative bacteria are global public health concerns. Data...
Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation.
Lasse Reimer, Hjalte Gram, Nanna Møller Jensen, Cristine Betzer, Li Yang, Lorrain Jin, Min Shi, Driss Boudeffa, Giuliana Fusco, Alfonso De Simone, Deniz Kirik, Hilal A Lashuel, Jing Zhang, Poul Henning Jensen
Mar 02, 2023
Aggregated α-synuclein (α-syn) accumulates in the neuronal Lewy body (LB) inclusions in Parkinson's disease (PD) and LB dementia. Yet, under nonpathological conditions, monomeric α-syn is hypothesized to exist in an equilibrium...
Analysis of microbial keratitis incidence, isolates and in-vitro antimicrobial susceptibility in the East of England
Malik Moledina, Harry W Roberts, Achyut Mukherjee, David Spokes, Dimitris Pimenides, Christopher Stephenson, Ramy Bassily, Madhavan S Rajan, James Myerscough
Feb 28, 2023
BACKGROUND/OBJECTIVES: To report the incidence, microbiological profile and in-vitro antimicrobial susceptibilities of microbial keratitis (MK) in the East of England (EoE) over a 6-year period. SUBJECTS/METHODS: A retrospective...
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