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Results: 149
A patient-reported outcome measure for patients with pituitary adenoma undergoing transsphenoidal surgery.
Elika Karvandi, John Gerrard Hanrahan, Danyal Zaman Khan, Pierre-Marc Boloux, Fion Bremner, Ivan Cabrilo, Neil Dorward, Joan Grieve, Sue Jackson, Glenda Jimenez, Inma Serrano, Victoria Anne Nowak, Angelos Kolias, Stephanie E Baldeweg, Hani Joseph Marcus
Aug 02, 2022
PURPOSE: Pituitary adenomas affect patients' quality-of-life (QoL) across several domains, with long-term implications even following gross-total resection or disease remission. While clinical outcomes can assess treatment...
A patient-reported outcome measure for patients with pituitary adenoma undergoing transsphenoidal surgery.
Quantitative Experimental Embryology
Experimental Embryology is often referred to as a classical approach of developmental biology that has been to some extent replaced by the introduction of molecular biology and genetic techniques to the field. Inspired by the...
Morphological Control of Cilia-Inspired Asymmetric Movements Using Nonlinear Soft Inflatable Actuators.
Edoardo Milana, Bert Van Raemdonck, Andrea Serrano Casla, Michael De Volder, Dominiek Reynaerts, Benjamin Gorissen
Jan 28, 2022
Soft robotic systems typically follow conventional control schemes, where actuators are supplied with dedicated inputs that are regulated through software. However, in recent years an alternative trend is being explored, where...
Dynamic Identification of thermodynamic parameters for Turbocharger Compressor Models
A novel experimental procedure is presented which allows simultaneous identification of heat and work transfer parameters for turbocharger compressor models. The method introduces a thermally transient condition and uses...
Fracture of laminated bamboo and the influence of preservative treatments
Thomas P.S. Reynolds, Bhavna Sharma, Erik Serrano, Per Johan Gustafsson, Michael H. Ramage
Oct 01, 2019
Treated bamboo can be made into large, durable structural elements which have the potential to become a transformative large-scale building material, but the fracture behaviour which determines their ultimate strength in...
Sono-photo-degradation of Carbamazepine in a thin falling film reactor
The photo-Fenton degradation of carbamazepine (CBZ) assisted with ultrasound radiation (US/UV/H2O2/Fe) was tested in a lab thin film reactor allowing high TOC removals (89% in 35 minutes). The synergism between the UV process...
Dynamic Identification of thermodynamic parameters for Turbocharger Compressor Models
A novel experimental procedure is presented which allows simultaneous identification of heat and work transfer parameters for turbocharger compressor models. The method introduces a thermally transient condition and uses...
An iPSC-derived vascular model of Marfan syndrome identifies key mediators of smooth muscle cell death.
Alessandra Granata, Felipe Serrano, William George Bernard, Madeline McNamara, Lucinda Low, Priya Sastry, Sanjay Sinha
Oct 31, 2016
Aortic Aneurysm Apoptosis Fibrillin-1 Gene Expression Regulation Humans Induced Pluripotent Stem Cells Kruppel-Like Factor 4 Kruppel-Like Transcription Factors Marfan Syndrome Models Biological Muscle Smooth Vascular Signal Transduction Transforming Growth Factor beta p38 Mitogen-Activated Protein Kinases
Increased canine pancreatic lipase immunoreactivity (cPLI) and 1,2-o-dilauryl-rac-glycero-3-glutaric acid-(6'-methylresorufin) ester (DGGR) lipase in dogs with evidence of portal hypertension and normal pancreatic histology
The clinical presentations of both liver disease and pancreatitis are nonspecific and overlapping, which may cause difficulty in diagnosis. In our retrospective pilot study, we assessed whether dogs with evidence of portal...
DGGR lipase (1 2-o-dilauryl-rac-glycero-3-glutaricacid-(6′-methylresorufin) ester) MAPSS (multiple acquired portosystemic shunts) Spec cPL (canine pancreas-specific lipase) cPLI (canine pancreatic lipase immunoreactivity) Dogs Liver portal hypertension Animals Dog Diseases Dogs Hypertension Portal LIPASE Pancreas Pancreatitis Pilot Projects Retrospective Studies
Sono-photo-degradation of Carbamazepine in a thin falling film reactor
The photo-Fenton degradation of carbamazepine (CBZ) assisted with ultrasound radiation (US/UV/H2O2/Fe) was tested in a lab thin film reactor allowing high TOC removals (89% in 35 minutes). The synergism between the UV process...
Fracture of laminated bamboo and the influence of preservative treatments
Thomas P.S. Reynolds, Bhavna Sharma, Erik Serrano, Per Johan Gustafsson, Michael H. Ramage
Oct 01, 2019
Treated bamboo can be made into large, durable structural elements which have the potential to become a transformative large-scale building material, but the fracture behaviour which determines their ultimate strength in...
Quantitative Experimental Embryology
Published by: MDPI
A Novel Human Pluripotent Stem Cell-Derived Neural Crest Model of Treacher Collins Syndrome Shows Defects in Cell Death and Migration.
Felipe Serrano, William George Bernard, Alessandra Granata, Dharini Iyer, Ben Steventon, Matthew Kim, Ludovic Vallier, Laure Gambardella, Sanjay Sinha
Dec 10, 2018
The neural crest (NC) is a transient multipotent cell population present during embryonic development. The NC can give rise to multiple cell types and is involved in a number of different diseases. Therefore, the development of...
Treacher Collins syndrome DIFFERENTIATION Disease Modeling Human pluripotent stem cells Neural Crest Adaptor Proteins Signal Transducing Animals Benzamides Cell Death Cell Differentiation Cell Movement Cellular Reprogramming Techniques Chick Embryo Dioxoles Fibroblast Growth Factor 2 Humans Mandibulofacial Dysostosis Neural Crest Neural Stem Cells Nuclear Proteins Phosphoproteins Pluripotent Stem Cells SOXE Transcription Factors Transcription Factor AP-2 Transcription Factors Twist-Related Protein 1
The Histone Deacetylase 9 Stroke-Risk Variant Promotes Apoptosis and Inflammation in a Human iPSC-Derived Smooth Muscle Cells Model.
Alessandra Granata, Ioannis Kasioulis, Felipe Serrano, James D Cooper, Matthew Traylor, Sanjay Sinha, Hugh S Markus
Apr 13, 2022
A common variant in the Histone Deacetylase 9 (HDAC9) gene is the strongest genetic risk for large-vessel stroke, and HDAC9 offers a novel target for therapeutic modulation. However, the mechanisms linking the HDAC9 variant with...
Validation of a commercial 1,2-o-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin) ester lipase assay for diagnosis of canine pancreatitis.
Emily L Goodband, Gonçalo Serrano, Fernando Constantino-Casas, Joy Archer, Penny J Watson, Tim L Williams
Apr 19, 2018
The objectives of this study were fourfold: technical validation of a commercial canine 1,2-o-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin) ester (DGGR) lipase assay, to calculate a reference interval for DGGR lipase...
Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by Induced Pluripotent Stem Cell Modeling.
Alpha-Synuclein Expression in the Oligodendrocyte Lineage
Mehdi Djelloul, Staffan Holmqvist, Antonio Boza-Serrano, Carla Azevedo, Maggie S Yeung, Stefano Goldwurm, Jonas Frisén, Tomas Deierborg, Laurent Roybon
Jun 01, 2020
In this study, we sought evidence for alpha-synuclein (ASYN) expression in oligodendrocytes, as a possible endogenous source of ASYN to explain its presence in glial inclusions found in multiple system atrophy (MSA) and...
Modeling Dynamical Positional Physical Data on Field Zones Occupied by Playing Positions in Elite-Level Futsal
Antipyrine removal by TiO<sub>2</sub> photocatalysis based on spinning disc reactor technology
Antonio Jose Exposito Serrano, D. A. Patterson, W. S. W. Mansor, J. M. Monteagudo, Emma Emanuelsson, I. Sanmartin, A. Duran
Feb 01, 2017
The photo-degradation of the emerging contaminant antipyrine (AP) was studied and optimized in a novel photocatalytic spinning disc reactor (SDR). A heterogeneous process (UV/H2O2/TiO2) was used. TiO2 was immobilized on the...
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