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Results: 78791
Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimer's-associated amyloid beta peptide.
Jordan H Cater, Janet R Kumita, Rafaa Zeineddine Abdallah, Guomao Zhao, Ana Bernardo-Gancedo, Amanda Henry, Wendy Winata, Mengna Chi, Brin SF Grenyer, Michelle L Townsend, Marie Ranson, Catalin S Buhimschi, D Stephen Charnock-Jones, Christopher M Dobson, Mark R Wilson, Irina A Buhimschi, Amy R Wyatt
Mar 11, 2019
Molecular Chaperones Preeclampsia Pregnancy protein misfolding Proteostasis Alzheimer Disease Amyloid beta-Peptides Female Humans Microscopy Electron Transmission Molecular Chaperones Peptide Fragments pre-eclampsia Pregnancy Pregnancy Proteins protein aggregation Pathological Protein Folding Protein Stability Proteostasis Deficiencies
Deterministic Model Investigation of Processes in a Heterogeneous E-Learning Environment
The investigation of characteristics of access and use of resources in different distributed environments in the network space is aimed at determining optimal levels for the basic parameters of the supported processes. On the...
Published by: IGI Global Scientific Publishing
An experimental and modelling investigation of the effect of the flow regime on the photocatalytic degradation of methylene blue on a thin film coated ultraviolet irradiated spinning disc reactor
In this work, the impact of wave regime and operational parameters on the photocatalytic degradation of methylene blue was investigated on a thin film coated ultra-violet spinning disc. In the employed experimental setup, the...
An experimental and modelling investigation of the effect of the flow regime on the photocatalytic degradation of methylene blue on a thin film coated ultraviolet irradiated spinning disc reactor
In this work, the impact of wave regime and operational parameters on the photocatalytic degradation of methylene blue was investigated on a thin film coated ultra-violet spinning disc. In the employed experimental setup, the...
The case for the photocatalytic spinning disc reactor as a process intensification technology
A spinning disc reactor was investigated as a process intensification technology for photocatalysis and compared with a conventional annular reactor. It was found that the average photonic efficiency achieved in the SDR was...
Prevention and Resolution of Labor Disputes
The study covers preventive dispute resolution methods in industrial relations, as well as empirical testing of hypotheses regarding labor disputes in Russia. The hypothesis regarding the impact of the number of laid-off...
Published by: IGI Global Scientific Publishing
A multi-objective decision making model for risk-based maintenance scheduling of railway earthworks
Aged earthworks constitute a major proportion of European rail infrastructures, the replacement and remediation of which poses a serious problem. Considering the scale of the networks involved, it is infeasible both in terms of...
A multi-objective decision making model for risk-based maintenance scheduling of railway earthworks
Aged earthworks constitute a major proportion of European rail infrastructures, the replacement and remediation of which poses a serious problem. Considering the scale of the networks involved, it is infeasible both in terms of...
Diagnosis and management of Sandifer syndrome in children with intractable neurological symptoms.
Irina Mindlina
Jan 23, 2020
Sandifer syndrome is a rare complication of gastro-oesophageal reflux disease (GERD) when a patient presents with extraoesophageal symptoms, typically neurological. The aim of this study was to review the existing literature and...
Gastro-oesophageal Reflux Disease Intractable Neurological Symptoms Misdiagnosis Sandifer Syndrome Anemia Iron-Deficiency Brain Diseases Child Developmental Disabilities Diagnosis Differential Diagnostic Errors Female Gastroesophageal Reflux Humans Male Peripheral Nervous System Diseases Risk Assessment Severity of Illness Index Torticollis Treatment Outcome United Kingdom
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Is Protein Folding a Thermodynamically Unfavorable, Active, Energy-Dependent Process?
The prevailing current view of protein folding is the thermodynamic hypothesis, under which the native folded conformation of a protein corresponds to the global minimum of Gibbs free energy G. We question this concept and show...
Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia).
Svetlana A Romanenko, Elena A Lyapunova, Abdusattor S Saidov, Patricia CM O'Brien, Natalia A Serdyukova, Malcolm A Ferguson-Smith, Alexander S Graphodatsky, Irina Bakloushinskaya
Dec 11, 2019
The involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles Ellobius, a group of subterranean rodents. The first description of their...
The case for the photocatalytic spinning disc reactor as a process intensification technology
A spinning disc reactor was investigated as a process intensification technology for photocatalysis and compared with a conventional annular reactor. It was found that the average photonic efficiency achieved in the SDR was...
Is Protein Folding a Thermodynamically Unfavorable, Active, Energy-Dependent Process?
The prevailing current view of protein folding is the thermodynamic hypothesis, under which the native folded conformation of a protein corresponds to the global minimum of Gibbs free energy G. We question this concept and show...
co-translational protein folding energy-dependent protein folding Entropy free energy free energy landscape Molecular Chaperones physical model of protein folding Protein Folding Algorithms Kinetics Models Molecular Models Theoretical Protein Conformation Protein Folding Protein Refolding Protein Stability Proteins Proteome Proteomics Recombinant Proteins Solubility Species Specificity Thermodynamics
Investigation of the effect of flow structure on the photocatalytic degradation of methylene blue and dehydroabietic acid in a spinning disc reactor
The ultraviolet irradiated thin lm coated spinning disc reactor is a new technol-
ogy for the intensication of heterogeneous photocatalytic reactions. This reactor
has previously been found to have a reaction rate maxima...
ogy for the intensication of heterogeneous photocatalytic reactions. This reactor
has previously been found to have a reaction rate maxima...
Temperament and arousal systems
This paper critically reviews the unidimensional construct of General Arousal as utilised by models of temperament in differential psychology for example, to underlie 'Extraversion'. Evidence suggests that specialization within...
“One tiny drop changes everything”
This paper uses the theory of speech acts to explore how entrepreneurs use language to construct the opportunities they set out to pursue. We use the case of Theranos (a journey from inspiring vision to criminal infamy) as a...
Entrepreneurial communication Entrepreneurial journey language Opportunity Opportunity construction Speech acts /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutions name=SDG 16 - Peace, Justice and Strong Institutions
Twin Pregnancies in Dairy Cattle
Multiple pregnancies have devastating consequences on the herd economy of dairy cattle. This observational study examines incidence patterns based on data from the ultrasonographic examination of 1130 multiple pregnancies in...
HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood
The infection of cultured monocyte-derived dendritic cells (DCs) with HIV-1 involves CD4 and CCR5 receptors, while transmission to T cells is enhanced at least in part by the lectin DC-SIGN/CD209. In the present study, we...
Published by: Rockefeller University
“One tiny drop changes everything”
This paper uses the theory of speech acts to explore how entrepreneurs use language to construct the opportunities they set out to pursue. We use the case of Theranos (a journey from inspiring vision to criminal infamy) as a...
Entrepreneurial communication Entrepreneurial journey language Opportunity Opportunity construction Speech acts /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutions name=SDG 16 - Peace, Justice and Strong Institutions
Investigation of the effect of flow structure on the photocatalytic degradation of methylene blue and dehydroabietic acid in a spinning disc reactor
The ultraviolet irradiated thin lm coated spinning disc reactor is a new technol-
ogy for the intensication of heterogeneous photocatalytic reactions. This reactor
has previously been found to have a reaction rate maxima...
ogy for the intensication of heterogeneous photocatalytic reactions. This reactor
has previously been found to have a reaction rate maxima...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Fast Track to Full Online Education in the Medical Field
The research explores the key issues specific to the online learning format. The scholars surveyed 1540 students and teachers to collect the data. The purpose was to identify and find solutions to the distance learning problems...
Published by: IGI Global Scientific Publishing
Periodic supply vessel planning under demand and weather uncertainty
We solve a periodic supply vessel planning problem under demand and weather uncertainty, arising in offshore of oil and gas production. Our study is motivated by the case of the Norwegian energy operator Equinor which supplied...
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