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Results: 207
Cover Image for In situ structure and assembly of the multidrug efflux pump AcrAB-TolC. View Article
In situ structure and assembly of the multidrug efflux pump AcrAB-TolC.
Xiaodong Shi, Muyuan Chen, Zhili Yu, James M Bell, Hans Wang, Isaac Forrester, Heather Villarreal, Joanita Jakana, Dijun Du, Ben F Luisi, Steven J Ludtke, Zhao Wang
Jun 13, 2019
Anti-Bacterial Agents Bacterial Outer Membrane Proteins Carrier Proteins Cryoelectron Microscopy Drug Resistance Multiple Bacterial Electron Microscope Tomography Escherichia coli Escherichia coli Proteins Intravital Microscopy Lipoproteins Membrane Transport Proteins Multidrug Resistance-Associated Proteins Peptidoglycan Periplasm Protein Binding Protein Structure Quaternary
Cover Image for In situ structure and assembly of the multidrug efflux pump AcrAB-TolC View Article
In situ structure and assembly of the multidrug efflux pump AcrAB-TolC
Xiaodong Shi, Muyuan Chen, Zhili Yu, James M. Bell, Hans Wang, Isaac Forrester, Heather Villarreal, Joanita Jakana, Dijun Du, Ben F. Luisi, Steven J. Ludtke, Zhao Wang
Jun 15, 2020
Abstract: Multidrug efflux pumps actively expel a wide range of toxic substrates from the cell and play a major role in intrinsic and acquired drug resistance. In Gram-negative bacteria, these pumps form tripartite assemblies...
article article
Cover Image for Non-invasive technical investigation of english portrait miniatures attributed to Nicholas Hilliard and Isaac Oliver View Article
Non-invasive technical investigation of english portrait miniatures attributed to Nicholas Hilliard and Isaac Oliver
F Fiorillo, L Burgio, CS Kimbriel, P Ricciardi
Jul 28, 2021
This study presents the results of the technical investigation carried out on several English portrait miniatures painted in the 16th and 17th century by Nicholas Hilliard and Isaac Oliver, two of the most famous limners...
English portrait miniatures Pigments painting technique Isaac Oliver Nicholas Hilliard non-invasive analysis Raman microscopy optical microscopy X-ray fluorescence spectroscopy
Cover Image for Model U.N. Conference to Focus on Peace, Security and Development View Article
Model U.N. Conference to Focus on Peace, Security and Development
Winthrop University
Jan 01, 0001
Isaac Wohl will speak at 7 p.m. March 20 in Tillman Auditorium. This is the 37th annual Model U.N. conference.
Published by: Winthrop University
Cover Image for Proximate Breast Cancer Factors Using Data Mining Classification Techniques View Chapter
Proximate Breast Cancer Factors Using Data Mining Classification Techniques
Alice Mensah, Isaac Asare
Jul 01, 2022
Breast cancer is the most common of all cancers and is the leading cause of cancer deaths in women worldwide. The classification of breast cancer data can be useful to predict the outcome of some diseases or discover the genetic...
Medicine and Healthcare Medical Technologies Medical Informatics Computer Science and Information Technology Physical Sciences and Engineering
Published by: IGI Global Scientific Publishing
Cover Image for The experiences of older carers of people with learning disabilities View Article
The experiences of older carers of people with learning disabilities
Rachel Forrester-Jones
Apr 30, 2021

Purpose: Because people with learning disabilities (LD) are living longer, their family carers are likely to continue their caring role for longer. This study aims to explore the experiences of older carers of people with LD....

adult social care Carer experiences Future plans Intellectual Disability learning disabilities older carers
Cover Image for Newton, Sir Isaac View Article
Newton, Sir Isaac
Cover Image for Efficacy of Electronic Monitoring View Article
Efficacy of Electronic Monitoring
Isaac Elking
Oct 18, 2022
The use of electronic performance monitoring is becoming increasingly widespread in conjunction with the digitalization of today's supply chains, yet the efficacy of these systems to improve desired performance outcomes is still...
Published by: IGI Global Scientific Publishing
Cover Image for Isaac Newton learns Hebrew View Article
Isaac Newton learns Hebrew
Michael Joalland, Scott Mandelbrote
Jan 25, 2016
Newton Hebrew Johnson Nova cubi Hebræi tabella
Cover Image for Specialist hospital treatment and care as reported by children with intellectual disabilities and a cleft lip and/or palate, their parents and healthcare professionals View Article
Specialist hospital treatment and care as reported by children with intellectual disabilities and a cleft lip and/or palate, their parents and healthcare professionals
Amanda Bates, Rachel Forrester-Jones, Michelle McCarthy
Feb 05, 2020

Background: Research into hospital treatment and care of children with intellectual disabilities is extremely limited, but available literature points to difficulties. Some children have a co-occurring condition alongside an...

children cleft health care hospital intellectual disabilities
Cover Image for Exploring the Growth in Police Engagement with Those Who Are Mentally Ill and the Developing Use of the Mental Capacity Act as an Alternative to Section 136 of the Mental Health Act View Article
Exploring the Growth in Police Engagement with Those Who Are Mentally Ill and the Developing Use of the Mental Capacity Act as an Alternative to Section 136 of the Mental Health Act
Allyn Thomas, Rachel Forrester-Jones, P. Hunt
Mar 01, 2021
Despite efforts of Parliament, the Home Office, police forces and health practitioners, the number of people detained under Section 136 of the Mental Health Act 1983 continues to rise. By analyzing quantitative data from...
Section 136 Mental Health Act policing Mentally Ill
Cover Image for Spring View Article
Spring
Isaac Oplanic
Jan 01, 0001
Creative Writing
Published by: Winthrop University
Cover Image for Older carers of people with learning disabilities View Article
Older carers of people with learning disabilities
Rachel Forrester-Jones
Jul 06, 2021

Purpose: Amongst other actions the Care Act 2014 emphasised the duties of local authorities (LA) to assess the needs of carers, as well as those they care for and to meet all eligible needs for support. This paper aims to...

older carers Learning disability Local Authority needs assessments Personnel Needs led assessments Carer assessments Learning disability Struggles Older carers Social Workers
Cover Image for Older carers of people with learning disabilities View Article
Older carers of people with learning disabilities
Rachel Forrester-Jones
Jul 06, 2021

Purpose: Amongst other actions the Care Act 2014 emphasised the duties of local authorities (LA) to assess the needs of carers, as well as those they care for and to meet all eligible needs for support. This paper aims to...

older carers Learning disability Local Authority needs assessments Personnel Needs led assessments Carer assessments Learning disability Struggles older carers Social Workers
Cover Image for Mechanism of efficient double-strand break repair by a long non-coding RNA. View Article
Mechanism of efficient double-strand break repair by a long non-coding RNA.
Roopa Thapar, Jing L Wang, Michal Hammel, Ruiqiong Ye, Ke Liang, Chengcao Sun, Ales Hnizda, Shikang Liang, Su S Maw, Linda Lee, Heather Villarreal, Isaac Forrester, Shujuan Fang, Miaw-Sheue Tsai, Tom L Blundell, Anthony J Davis, Chunru Lin, Susan P Lees-Miller, Terence R Strick, John A Tainer
Nov 30, 2020
Mechanistic studies in DNA repair have focused on roles of multi-protein DNA complexes, so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet, lncRNA LINP1 is over-expressed in multiple cancers...
DNA Breaks Double-Stranded DNA End-Joining Repair DNA-Binding Proteins HeLa Cells Humans Ku Autoantigen Protein Binding Protein Multimerization RNA Long Noncoding
Cover Image for The experiences of older carers of people with learning disabilities View Article
The experiences of older carers of people with learning disabilities
Rachel Forrester-Jones
Apr 30, 2021

Purpose: Because people with learning disabilities (LD) are living longer, their family carers are likely to continue their caring role for longer. This study aims to explore the experiences of older carers of people with LD....

adult social care Carer experiences Future plans Intellectual Disability learning disabilities older carers
Cover Image for An Exploratory Study of Attitudes toward Autism Amongst Church-Going Christians in the South East of England, United Kingdom View Article
An Exploratory Study of Attitudes toward Autism Amongst Church-Going Christians in the South East of England, United Kingdom
Krysia Waldock, Rachel Forrester-Jones
Oct 01, 2020

Access to church communities can be difficult for autistic people. Whilst specific autism guidelines are available for churches to follow, their dissemination among church communities, as well as churchgoers’ attitudes...

autism inclusion social inclusion spirituality
Cover Image for Adult Social Care and Unmet Needs View Title
Adult Social Care and Unmet Needs
Rachel Forrester-Jones, Mark Hammond
Sep 22, 2020
The UK social care system, which in its current form dates largely from the post- Second World War welfare state settlement, has both expanded hugely in recent decades, and by common consent is now dysfunctional in various...
adult social care unmet needs disability older people Access Social Care
Published by: Centre for the Analysis of Social Policy
Cover Image for The experience of stigma among adults with Tourette's syndrome View Title
The experience of stigma among adults with Tourette's syndrome
Melina Malli, Rachel Forrester-Jones
Mar 20, 2021
Cover Image for A case study View Title
A case study
Jennifer Beecham, Rachel Forrester-Jones
Jan 01, 0001
Background People with intellectual disabilities have a shorter life expectancy but health care improvements mean that they are living longer, with the associated health difficulties. Research into ways of supporting people with...
costs Intellectual Disability Dementia
Cover Image for A case study View Title
A case study
Jennifer Beecham, Rachel Forrester-Jones
Jan 01, 0001
Background People with intellectual disabilities have a shorter life expectancy but health care improvements mean that they are living longer, with the associated health difficulties. Research into ways of supporting people with...
costs Intellectual Disability Dementia
Cover Image for The dynamic effects of becoming disabled on work, wages and wellbeing in the UK from 1991 to 2018 View Article
The dynamic effects of becoming disabled on work, wages and wellbeing in the UK from 1991 to 2018
Matt Dickson, Tina Skinner, Rachel Forrester-Jones
Oct 23, 2024
Over recent decades it has consistently been shown that disabled adults in the UK fare worse in the labour market and have lower levels of wellbeing than non-disabled adults. However, this is in part due to the selection into...
disabled employment Policy wage Wellbeing
Cover Image for Adult Social Care and Unmet Needs View Title
Adult Social Care and Unmet Needs
Rachel Forrester-Jones, Mark Hammond
Sep 22, 2020
The UK social care system, which in its current form dates largely from the post- Second World War welfare state settlement, has both expanded hugely in recent decades, and by common consent is now dysfunctional in various...
adult social care unmet needs disability older people Access Social Care
Published by: Centre for the Analysis of Social Policy
Cover Image for An Investigation into the use of the Deprivation of Liberty Safeguards with People with Intellectual Disabilities View Article
An Investigation into the use of the Deprivation of Liberty Safeguards with People with Intellectual Disabilities
Kate Blamires, Rachel Forrester-Jones, Glynis Murphy
Jul 31, 2017

Background: This small, qualitative study sought to develop a richer understanding of the way in which the deprivation of liberty safeguards (DOLS) were being used for people with intellectual disabilities. It is important to...

challenging behaviour deprivation of liberty Learning disability Mental capacity restriction social care
Cover Image for The dynamic effects of becoming disabled on work, wages and wellbeing in the UK from 1991 to 2018 View Article
The dynamic effects of becoming disabled on work, wages and wellbeing in the UK from 1991 to 2018
Matt Dickson, Tina Skinner, Rachel Forrester-Jones
Oct 23, 2024
Over recent decades it has consistently been shown that disabled adults in the UK fare worse in the labour market and have lower levels of wellbeing than non-disabled adults. However, this is in part due to the selection into...
disabled employment Policy wage Wellbeing

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