Search
Results: 51
Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A.
Ikenna E Ndukwe, Xiao Wang, Nelson YS Lam, Kristaps Ermanis, Kelsey L Alexander, Matthew J Bertin, Gary E Martin, Garrett Muir, Ian Paterson, Robert Britton, Jonathan M Goodman, Eric JN Helfrich, Jörn Piel, William H Gerwick, R Thomas Williamson
Jun 09, 2020
Characterization of the complex molecular scaffold of the marine polyketide natural product phormidolide A represents a challenge that has persisted for nearly two decades. In light of discordant results arising from recent...
Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods.
Blebs and pseudopods can both power cell migration, with blebs often favored in tissues, where cells encounter increased mechanical resistance. To investigate how migrating cells detect and respond to mechanical forces, we used...
Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV Gag p24 protein
Mass Spectrometry (MS) is becoming a preferred method to identify class I and class II peptides presented on major histocompability complexes (MHC) on antigen presenting cells (APC). We describe a combined computational and MS...
Published by: Rockefeller University
Cortical microtubule nucleation can organise the cytoskeleton of Drosophila oocytes to define the anteroposterior axis.
Philipp Khuc Trong, Hélène Doerflinger, Jörn Dunkel, Daniel St Johnston, Raymond E Goldstein
Oct 01, 2015
Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods.
Blebs and pseudopods can both power cell migration, with blebs often favored in tissues, where cells encounter increased mechanical resistance. To investigate how migrating cells detect and respond to mechanical forces, we used...
DNA recovery from wild chimpanzee tools.
Fiona A Stewart, Alexander K Piel, Lydia Luncz, Joanna Osborn, Yingying Li, Beatrice H Hahn, Michael Haslam
May 23, 2018
Most of our knowledge of wild chimpanzee behaviour stems from fewer than 10 long-term field sites. This bias limits studies to a potentially unrepresentative set of communities known to show great behavioural diversity on small...
A predictive account of how novelty influences declarative memory.
A rich body of studies in the human and non-human literature has examined the question how novelty influences memory. For a variety of different stimuli, ranging from simple objects and words to vastly complex scenarios, the...
Mode Selection in Compressible Active Flow Networks.
Coherent, large-scale dynamics in many nonequilibrium physical, biological, or information transport networks are driven by small-scale local energy input. Here, we introduce and explore an analytically tractable nonlinear model...
Elevated circulating Sclerostin concentrations in individuals with high bone mass, with and without LRP5 mutations.
Celia L Gregson, Kenneth ES Poole, Eugene V McCloskey, Emma L Duncan, Jörn Rittweger, William D Fraser, George Davey Smith, Jonathan H Tobias
Oct 06, 2015
Adaptor Proteins Signal Transducing Adult Aged Aged 80 and over Bone Density Bone Morphogenetic Proteins Case-Control Studies Female Genetic Markers Humans Hyperostosis Low Density Lipoprotein Receptor-Related Protein-5 Male Middle Aged Mutation Osteochondrodysplasias Syndactyly United Kingdom Young Adult
The Ursinus Weekly, May 3, 1973
John T. Fidler, Elsie Van Wagoner, Pat Belmont, David Ochocki, Deborah McConomy, Nancy Frye, Richard Whaley, Mark M. Borish, James Cochran, Gary Griffith, Rodger Blind, Robert Vietri, Susan Petersen, Helen Ludwig, Ruthann Connell
Jan 01, 0001
Meisters sing praise about Spring tour CCC's squad leaders program will have more work, closer contact with Frosh USGA selects new J-Board members IF weekend starts today Convocation to honor U.C. basketball team Phi Psi...
Ursinus College Collegeville Pennsylvania newspaper Meistersingers Central Coordinating Committee fraternities student government Judiciary Board F. Scott Pierce Phi Alpha Psi Zeta Chi Easter egg hunt basketball team restaurant explosion Huntingdon Mt. Union summer school Watergate Derk Visser Sara Sellers Socratic Club Hiroshi Obayashi Buddhism Perkiomen Valley Art Center Gerard Piel baseball track softball tennis lacrosse cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
NICER/NuSTAR Characterization of 4U 1957+11
Abstract
4U 1957+11 is a black hole candidate system that has been in a soft X-ray spectral state since its discovery. We present analyses of recent joint NICER and NuSTAR spectra...
Erin Barillier, Victoria Grinberg, David Horn, Michael A Nowak, Ronald A Remillard, James F Steiner, Dominic J Walton, Jörn Wilms
Feb 22, 2023
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR.
Michael Scherer, Gilles Gasparoni, Souad Rahmouni, Tatiana Shashkova, Marion Arnoux, Edouard Louis, Arina Nostaeva, Diana Avalos, Emmanouil T Dermitzakis, Yurii S Aulchenko, Thomas Lengauer, Paul A Lyons, Michel Georges, Jörn Walter
Oct 18, 2021
Background
Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease. There is a need for systematic approaches not only for...
Published by: Epigenetics & chromatin
Cellulose Nanocrystal-Templated Tin Dioxide Thin Films for Gas Sensing.
Alesja Ivanova, Bruno Frka-Petesic, Andrej Paul, Thorsten Wagner, Askhat N Jumabekov, Yury Vilk, Johannes Weber, Jörn Schmedt Auf der Günne, Silvia Vignolini, Michael Tiemann, Dina Fattakhova-Rohlfing, Thomas Bein
Jan 15, 2020
Porous tin dioxide is an important low-cost semiconductor applied in electronics, gas sensors, and biosensors. Here, we present a versatile template-assisted synthesis of nanostructured tin dioxide thin films using cellulose...
Development and validation of Gaucher disease type 1 (GD1)-specific patient-reported outcome measures (PROMs) for clinical monitoring and for clinical trials.
Deborah Elstein, Nadia Belmatoug, Patrick Deegan, Özlem Göker-Alpan, Derralynn A Hughes, Ida Vanessa D Schwartz, Neal Weinreb, Nicola Bonner, Charlotte Panter, Donna Fountain, Andrew Lenny, Louise Longworth, Rachael Miller, Koonal Shah, Jörn Schenk, Rohini Sen, Ari Zimran
Feb 09, 2022
BACKGROUND: Disease-specific patient-reported outcome measures (PROMs) are fundamental to understanding the impact on, and expectations of, patients with genetic disorders, and can facilitate constructive and educated...
Development and validation of Gaucher disease type 1 (GD1)-specific patient-reported outcome measures (PROMs) for clinical monitoring and for clinical trials.
Deborah Elstein, Nadia Belmatoug, Patrick Deegan, Özlem Göker-Alpan, Derralynn A Hughes, Ida Vanessa D Schwartz, Neal Weinreb, Nicola Bonner, Charlotte Panter, Donna Fountain, Andrew Lenny, Louise Longworth, Rachael Miller, Koonal Shah, Jörn Schenk, Rohini Sen, Ari Zimran
Jan 10, 2022
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR.
Michael Scherer, Gilles Gasparoni, Souad Rahmouni, Tatiana Shashkova, Marion Arnoux, Edouard Louis, Arina Nostaeva, Diana Avalos, Emmanouil T Dermitzakis, Yurii S Aulchenko, Thomas Lengauer, Paul A Lyons, Michel Georges, Jörn Walter
Sep 27, 2021
BACKGROUND: Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease. There is a need for systematic approaches not only for...
Surveillance of SARS-CoV-2 in Frankfurt am Main from October to December 2020 Reveals High Viral Diversity Including Spike Mutation N501Y in B.1.1.70 and B.1.1.7.
Marek Widera, Barbara Mühlemann, Victor M Corman, Tuna Toptan, Jörn Beheim-Schwarzbach, Niko Kohmer, Julia Schneider, Annemarie Berger, Talitha Veith, Christiane Pallas, Tobias Bleicker, Udo Goetsch, Julia Tesch, Rene Gottschalk, Terry C Jones, Sandra Ciesek, Christian Drosten
May 03, 2021
BACKGROUND: International travel is a major driver of the introduction and spread of SARS-CoV-2. AIM: To investigate SARS-CoV-2 genetic diversity in the region of a major transport hub in Germany, we characterized the viral...
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR
MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs.
Mélanie A Eckersley-Maslin, Valentine Svensson, Christel Krueger, Thomas M Stubbs, Pascal Giehr, Felix Krueger, Ricardo J Miragaia, Charalampos Kyriakopoulos, Rebecca V Berrens, Inês Milagre, Jörn Walter, Sarah A Teichmann, Wolf Reik
May 16, 2019
Mouse embryonic stem cells are dynamic and heterogeneous. For example, rare cells cycle through a state characterized by decondensed chromatin and expression of transcripts, including the Zscan4 cluster and MERVL endogenous...
DNA Methylation MERVL Zscan4 Chromatin Embryonic Stem Cell Endogenous retrovirus imprint preimplantation reprogramming Animals Cell Cycle Cellular Reprogramming Chromatin DNA Methylation DNA Modification Methylases endogenous retroviruses Epigenesis Genetic Genome Genomic Imprinting Induced Pluripotent Stem Cells Mice Mouse embryonic stem cells Multigene Family RNA Messenger Single-Cell Analysis Transcription Factors Transcriptional Activation Transcriptome
Genomes of coral dinoflagellate symbionts highlight evolutionary adaptations conducive to a symbiotic lifestyle.
M Aranda, Y Li, YJ Liew, S Baumgarten, O Simakov, MC Wilson, J Piel, H Ashoor, S Bougouffa, VB Bajic, T Ryu, T Ravasi, T Bayer, G Micklem, H Kim, J Bhak, TC LaJeunesse, CR Voolstra
Aug 01, 2018
Despite half a century of research, the biology of dinoflagellates remains enigmatic: they defy many functional and genetic traits attributed to typical eukaryotic cells. Genomic approaches to study dinoflagellates are often...
|
|< |
< |
1 |