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Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses.
CTL are held to be an important host defense mechanism in persistent herpes-virus infections. We have therefore studied the nature and specificity of human cytomegalovirus (HCMV)-specific CTL in normal persistently infected...
Applications of inverse gas chromatography in the study of liquid crystalline stationary phases
We describe measurements on a number of low-molar-mass and polymeric liquid crystals that contain the same mesogenic groups. Transition temperatures for the mesophases have been measured and the supercooled region of...
Applications of inverse gas chromatography in the study of liquid crystalline stationary phases
We describe measurements on a number of low-molar-mass and polymeric liquid crystals that contain the same mesogenic groups. Transition temperatures for the mesophases have been measured and the supercooled region of...
CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion.
Usheer Kanjee, Christof Grüring, Mudit Chaand, Kai-Min Lin, Elizabeth Egan, Jale Manzo, Patrick L Jones, Tiffany Yu, Robert Barker, Michael P Weekes, Manoj T Duraisingh
May 23, 2018
During malaria blood-stage infections, Plasmodium parasites interact with the RBC surface to enable invasion followed by intracellular proliferation. Critical factors involved in invasion have been identified using biochemical...
BSG CD44 CRISPR/Cas9 Plasmodium falciparum parasite invasion Antigens Protozoan Basigin CRISPR-Cas Systems Carrier Proteins Cell Differentiation Cell Line Tumor Clustered Regularly Interspaced Short Palindromic Repeats Epigenesis Genetic Erythrocytes Gene Knockout Techniques Hematopoietic Stem Cells host-parasite interactions Humans Hyaluronan Receptors K562 Cells Leukemia Erythroblastic Acute Ligands Malaria Malaria Falciparum Plasmodium falciparum Proteomics Protozoan Proteins
The recognition of money work as a specialty in the family courts by the creation of a national network of Financial Remedies Units
Financial remedies (or money) work has a curious status in the family court.
Children cases in the family court are subject to a careful allocation and gate-keeping procedure, following detailed guidance from the President of...
Exotic bilayer crystals in a strong magnetic field
Electron bilayers in a strong magnetic field exhibit insulating behavior for a wide range of interlayer separation d for total Landau level fillings ν ≤ 1 / 2 , which has been interpreted in terms of a pinned crystal. We study...
Avoiding Bias in Measurements of Fundamental Constants from High Resolution Quasar Spectra<sup>†</sup>
Recent advances in spectroscopic instrumentation and calibration methods dramatically improve the quality of quasar spectra. Supercomputer calculations show that, at high spectral resolution, procedures used in some...
Understanding the Role of Duration of Vaccine Protection with MenAfriVac
We previously developed a transmission dynamic model of Neisseria meningitidis serogroup A (NmA) with the aim of forecasting the relative benefits of different immunisation strategies with MenAfriVac. Our findings suggested that...
Costs of switching to low global warming potential inhalers. An economic and carbon footprint analysis of NHS prescription data in England.
Cryo-EM Structure of the Rhodobacter sphaeroides Light-Harvesting 2 Complex at 2.1 Å
Pu Qian, David JK Swainsbury, Tristan I Croll, Pablo Castro-Hartmann, Giorgio Divitini, Kasim Sader, C Neil Hunter
Oct 29, 2021
Light-harvesting 2 (LH2) antenna complexes augment the collection of solar energy in many phototrophic bacteria. Despite its frequent role as a model for such complexes, there has been no three-dimensional (3D) structure...
Prediction of Autism at 3 Years from Behavioural and Developmental Measures in High-Risk Infants
We integrated multiple behavioural and developmental measures from multiple time-points using machine learning to improve early prediction of individual Autism Spectrum Disorder (ASD) outcome. We examined Mullen Scales of Early...
What is the impact of e-cigarette adverts on children's perceptions of tobacco smoking? An experimental study.
Structural and functional insights into DNA-end processing by the archaeal HerA helicase-NurA nuclease complex
Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch
Angus H Forster, Katey Witham, Alexandra CI Depelsenaire, Margaret Veitch, James W Wells, Adam Wheatley, Melinda Pryor, Jason D Lickliter, Barbara Francis, Steve Rockman, Jesse Bodle, Peter Treasure, Julian Hickling, Germain JP Fernando
Apr 14, 2020
BACKGROUND: The Vaxxas high-density microarray patch (HD-MAP) consists of a high density of microprojections coated with vaccine for delivery into the skin. Microarray patches (MAPs) offer the possibility of improved vaccine...
Administration Cutaneous Adolescent Adult Antibodies Viral Australia Cells Cultured Drug Stability Female Humans Immunogenicity Vaccine Immunoglobulin A Influenza A virus H1N1 Subtype Influenza Vaccines Influenza Human Injections Intramuscular Male Saliva T-Lymphocytes Time Factors Transdermal Patch Treatment Outcome Vaccination Young Adult
Use of standard analytical tools to detect small amounts of smalt in the presence of ultramarine as observed in 15th-century Venetian illuminated manuscripts
P Ricciardi, KA Dooley, D MacLennan, G Bertolotti, F Gabrieli, CS Patterson, JK Delaney
Mar 21, 2022
Nipple- and areola-sparing mastectomy for the treatment of breast cancer
$\textbf{Background}$
The efficacy and safety of nipple-sparing mastectomy and areola-sparing mastectomy for the treatment of breast cancer are still questionable. It is estimated that the local recurrence rates following...
Double dissociation of the requirement for GluN2B- and GluN2A-containing NMDA receptors in the destabilization and restabilization of a reconsolidating memory
Indole
Indole is a key environmental cue that is used by many organisms. Based on its biochemistry, we suggest indole is used so universally, and by such different organisms, because it derives from the metabolism of tryptophan, a...
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