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Specialized Educational Leadership for Rural Students Living in Poverty
To serve students living in rural poverty, school leaders must understand intimately the specific challenges that students face. Equally, leaders must embrace and leverage the funds of knowledge and assets that these students...
Metacognitive insight into cognitive performance in Huntington's disease gene carriers.
OBJECTIVES: Insight is an important predictor of quality of life in Huntington's disease and other neurodegenerative conditions. However, estimating insight with traditional methods such as questionnaires is challenging and...
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Closed-loop insulin delivery system enhances type 1 diabetes glycemic control.
Julia Fuchs, Roman Hovorka
Feb 28, 2020
Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, et al. Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes. N Engl J Med 2019;381:1707-17. Question Among patients with type 1...
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The Carbon Savings and Health Co-Benefits from the Introduction of Mass Rapid Transit System in Greater Kuala Lumpur, Malaysia
SCK and JHH: Research was funded by the United Nations University- International Institute for Global Health and the National University of Malaysia under the project codes of UNU-IIGH 80814 and FF-2014-400, respectively. MT...
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Artefactual nanoparticle activation of the inflammasome platform
AIM: To determine whether in vitro experimental conditions dictate cellular activation of the inflammasome by apatitic calcium phosphate nanoparticles. MATERIAL & METHODS: The responses of blood-derived primary human cells to in...
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A stochastic approach to unitary coupled cluster.
Unitary coupled cluster (UCC), originally developed as a variational alternative to the popular traditional coupled cluster method, has seen a resurgence as a functional form for use on quantum computers. However, the number of...
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Tear ferning in normal dogs and dogs with keratoconjunctivitis sicca
DL Williams, H Hewitt
Jan 15, 2018
This study evaluates tear ferning as an ancillary technique for the evaluation of the canine tear film in normal eyes and eyes affected by keratoconjunctivitis sicca (KCS). Thirty dogs with KCS and 50 control dogs with normal...
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Two–dimensional viscoplastic dambreaks
We report the results of computations for two–dimensional dambreaks of viscoplastic fluid, focusing on the phenomenology of the collapse, the mode of initial failure, and the final shape of the slump. The volume-of-fluid method...
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Factors Influencing Security Incidents on Personal Computing Devices
Organizations expect their employees to connect securely to the organization's computer systems. Often these employees use their personal computers to access the organization's networks. This research explores whether these same...
Stable and unstable miscible displacements in layered porous media.
The effect of permeability heterogeneities and viscosity variations on miscible displacement processes in porous media is examined using high-resolution numerical simulations and reduced theoretical modelling. The planar...
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The Effect of Convective Injection of Ice on Stratospheric Water Vapor in a Changing Climate
Abstract: Stratospheric water vapor affects the Earth's radiative balance and stratospheric chemistry, yet its future changes are uncertain and not fully understood. The influence of deep convection on stratospheric water vapor...
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Flu transcription captured in action.
Aartjan JW Te Velthuis
Jun 25, 2019
Viral mRNA synthesis is an essential step in the influenza virus replication cycle and is a prime target for the development of new antivirals. New structures of the influenza virus RNA polymerase now unveil previously unknown...
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Common and unique features of viral RNA-dependent polymerases.
Aartjan JW Te Velthuis
Jul 30, 2018
Eukaryotes and bacteria can be infected with a wide variety of RNA viruses. On average, these pathogens share little sequence similarity and use different replication and transcription strategies. Nevertheless, the members of...
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Initiation, Elongation, and Realignment during Influenza Virus mRNA Synthesis.
The RNA-dependent RNA polymerase (RdRp) of the influenza A virus replicates and transcribes the viral genome segments in the nucleus of the host cell. To transcribe these viral genome segments, the RdRp "snatches" capped RNA...
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A physiological increase in maternal cortisol alters uteroplacental metabolism in the pregnant ewe.
KEY POINTS: Fetal nutrient supply is dependent, in part, upon the transport capacity and metabolism of the placenta. The stress hormone, cortisol, alters metabolism in the adult and fetus but it is not known whether cortisol in...
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