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Scholarship Endowment Commemorates Late Alumna Lin Fearrington Thomas '81, '83
Winthrop University
Jan 01, 0001
Recent endowment has made the Lin Fearrington Thomas Scholarship a permanent fund at Winthrop. Thomas earned B.A. and M.B.A. degrees as a post-traditional student in the 1980s.
Published by: Winthrop University
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
DREAM represses distinct targets by cooperating with different THAP domain proteins.
Csenge Gal, Francesco Nicola Carelli, Alex Appert, Chiara Cerrato, Ni Huang, Yan Dong, Jane Murphy, Andrea Frapporti, Julie Ahringer
Sep 27, 2021
The DREAM (dimerization partner [DP], retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell-cycle and other genes, but its mechanism of action is unclear. Here, we demonstrate that two...
dream H2A.Z H3K9me2 THAP lin-15B lin-35 lin-36 quiescence retinoblastoma TRANSCRIPTIONAL REPRESSION Animals Animals Genetically Modified Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Proteins DNA Methylation E2F Transcription Factors Gene Expression Regulation Histones Promoter Regions Genetic Protein Binding Protein Interaction Domains and Motifs Retinoblastoma Protein Transcription Factors
A protein complex required for polar growth of rhizobial infection threads
Cheng-Wu Liu, Andrew Breakspear, Nicola Stacey, Kim Findlay, Jin Nakashima, Karunakaran Ramakrishnan, Miaoxia Liu, Fang Xie, Gabriella Endre, Fernanda de Carvalho-Niebel, Giles E. D. Oldroyd, Michael K. Udvardi, Joëlle Fournier, Jeremy D. Murray
Jun 27, 2020
Abstract: During root nodule symbiosis, intracellular accommodation of rhizobia by legumes is a prerequisite for nitrogen fixation. For many legumes, rhizobial colonization initiates in root hairs through transcellular infection...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
Apr 02, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion.
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
May 15, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
Animals Basement Membrane Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Checkpoints Cell Differentiation Cell Proliferation G1 Phase Cell Cycle Checkpoints Gene Expression MDS1 and EVI1 Complex Locus Protein Proto-Oncogene Mas Proto-Oncogene Proteins c-fos Proto-Oncogenes Receptors Notch Signal Transduction Transcription Factors
A novel deep intronic variant strongly associates with Alkaptonuria.
Chien-Yi Lai, I-Jung Tsai, Pao-Chin Chiu, David B Ascher, Yin-Hsiu Chien, Yu-Hsuan Huang, Yi-Lin Lin, Wuh-Liang Hwu, Ni-Chung Lee
Oct 22, 2021
Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The epidemiology of alkaptonuria in East Asia is not...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion.
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
Apr 24, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
Published by: PLoS genetics
A novel deep intronic variant strongly associates with Alkaptonuria.
Chien-Yi Lai, I-Jung Tsai, Pao-Chin Chiu, David B Ascher, Yin-Hsiu Chien, Yu-Hsuan Huang, Yi-Lin Lin, Wuh-Liang Hwu, Ni-Chung Lee
Jan 06, 2022
Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The epidemiology of alkaptonuria in East Asia is not...
Interpreting the star formation - extinction relation with MaNGA
Huan Li, Stijn Wuyts, Lei Hao, Lin Lin, Man I Lam, Médéric Boquien, Brett H. Andrews, Donald P. Schneider
Feb 11, 2019
We investigate the resolved relation between local extinction and star formation surface density within nearby star-forming galaxies selected from the MaNGA survey. Balmer decrement measurements imply an extinction of the Hα...
Interpreting the star formation - extinction relation with MaNGA
Huan Li, Stijn Wuyts, Lei Hao, Lin Lin, Man I Lam, Médéric Boquien, Brett H. Andrews, Donald P. Schneider
Feb 11, 2019
We investigate the resolved relation between local extinction and star formation surface density within nearby star-forming galaxies selected from the MaNGA survey. Balmer decrement measurements imply an extinction of the Hα...
Topological phase change transistors based on tellurium Weyl semiconductor.
Jiewei Chen, Ting Zhang, Jingli Wang, Lin Xu, Ziyuan Lin, Jidong Liu, Cong Wang, Ning Zhang, Shu Ping Lau, Wenjing Zhang, Manish Chhowalla, Yang Chai
Jul 11, 2022
Modern electronics demand transistors with extremely high performance and energy efficiency. Charge-based transistors with conventional semiconductors experience substantial heat dissipation because of carrier scattering. Here...
Closed-loop insulin delivery system enhances type 1 diabetes glycemic control.
Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, et al. Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes. N Engl J Med 2019;381:1707-17.
Question
Among patients with type 1...
A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress.
Alicia N McMurchy, Przemyslaw Stempor, Tessa Gaarenstroom, Brian Wysolmerski, Yan Dong, Darya Aussianikava, Alex Appert, Ni Huang, Paulina Kolasinska-Zwierz, Alexandra Sapetschnig, Eric A Miska, Julie Ahringer
Aug 17, 2017
Repetitive sequences derived from transposons make up a large fraction of eukaryotic genomes and must be silenced to protect genome integrity. Repetitive elements are often found in heterochromatin; however, the roles and...
C. elegans DNA Damage Chromosomes evolutionary biology Genes Genomics Germ line Heterochromatin nuclear RNAi piRNA repetitive elements Animals Apoptosis Caenorhabditis elegans Caenorhabditis elegans Proteins Chromosomal Proteins Non-Histone DNA Repair Gene Expression Regulation Germ Cells Heterochromatin Interspersed Repetitive Sequences RNA Interference RNA Small Interfering
Regulation of B Lymphocyte Development by Histone H2A Deubiquitinase BAP1.
Yun Hsiao Lin, Yue Liang, Hanchen Wang, Lin Tze Tung, Michael Förster, Poorani Ganesh Subramani, Javier M Di Noia, Simon Clare, David Langlais, Anastasia Nijnik
Jun 07, 2021
BAP1 is a deubiquitinase (DUB) of the Ubiquitin C-terminal Hydrolase (UCH) family that regulates gene expression and other cellular processes, via deubiquitination of histone H2AK119ub and other substrates. BAP1 is an important...
B Cell Development B cells epigenetic regulation Mouse models Transcriptional regulation Animals B-Lymphocytes Cell Lineage Cell Proliferation Cells Cultured Epigenesis Genetic Female Gene Expression Regulation Developmental Histones Lymphocyte Activation Male Mice Inbred C57BL Mice Knockout Phenotype Precursor Cells B-Lymphoid Protein Processing Post-Translational Transcription Genetic Tumor Suppressor Proteins Ubiquitin Thiolesterase Ubiquitination
Novel near-infrared II aggregation-induced emission dots for in vivo bioimaging.
Jiacheng Lin, Xiaodong Zeng, Yuling Xiao, Lin Tang, Jinxia Nong, Yufang Liu, Hui Zhou, Bingbing Ding, Fuchun Xu, Hanxing Tong, Zixin Deng, Xuechuan Hong
May 28, 2020
Near-infrared II fluorescence imaging holds great promise for in vivo imaging and imaging-guided surgery with deep penetration and high spatiotemporal resolution. However, most NIR-II aromatic luminophores suffer from the...
A Developmental Pathway for Epithelial-to-Motoneuron Transformation in C. Elegans
Alina Rashid
Jan 01, 0001
During animal development, neurons and neuron-like cells are generated from progenitor cells that often line tubes. For example, in the developing spinal cord, basal processes of radial glial stem cells line the fluid-filled...
Published by: Rockefeller University
The Carbon Savings and Health Co-Benefits from the Introduction of Mass Rapid Transit System in Greater Kuala Lumpur, Malaysia
SCK and JHH: Research was funded by the United Nations University- International Institute for Global Health and the National University of Malaysia under the project codes of UNU-IIGH 80814 and FF-2014-400, respectively.
MT...
Exosome-like nanoplatform modified with targeting ligand improves anti-cancer and anti-inflammation effects of imperialine.
Qing Lin, Mengke Qu, Bingjie Zhou, Hirak K Patra, Zihan Sun, Qiong Luo, Wenyu Yang, Yongcui Wu, Yu Zhang, Lin Li, Lang Deng, Leilei Wang, Tao Gong, Qin He, Ling Zhang, Xun Sun, Zhirong Zhang
Sep 19, 2019
Currently, most anti-cancer therapies are still haunted by serious and deleterious adverse effects. Here, we report a highly biocompatible tumor cell-targeting delivery systems utilizing exosome-like vesicles (ELVs) that...
Exosome-like vesicles Imperialine Inflammation Micelle-aided drug loading NF-κB pathway Non-Small Cell Lung Cancer Animals Anti-Inflammatory Agents Antineoplastic Agents Carcinoma Non-Small-Cell Lung Cell Line Cevanes Exosomes Humans Integrin alpha3 Ligands Lung Neoplasms Male Mice Inbred BALB C Mice Nude NANOSTRUCTURES Oligopeptides
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