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Results: 363
Closed-loop insulin delivery system enhances type 1 diabetes glycemic control.
Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, et al. Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes. N Engl J Med 2019;381:1707-17.
Question
Among patients with type 1...
The Carbon Savings and Health Co-Benefits from the Introduction of Mass Rapid Transit System in Greater Kuala Lumpur, Malaysia
SCK and JHH: Research was funded by the United Nations University- International Institute for Global Health and the National University of Malaysia under the project codes of UNU-IIGH 80814 and FF-2014-400, respectively.
MT...
Sleep quality and its clinical associations in trichotillomania and skin picking disorder.
BACKGROUND: Trichotillomania (TTM) is characterized by recurrent hair pulling and associated hair loss. Skin picking disorder (SPD) is characterized by recurrent skin picking and associated scarring or tissue damage. Both...
A stochastic approach to unitary coupled cluster.
Unitary coupled cluster (UCC), originally developed as a variational alternative to the popular traditional coupled cluster method, has seen a resurgence as a functional form for use on quantum computers. However, the number of...
Problematic internet use
Konstantinos Ioannidis, Sarah A Redden, Stephanie Valle, Samuel R Chamberlain, Jon E Grant
Apr 16, 2019
OBJECTIVE: Problematic internet users suffer from impairment in a variety of cognitive domains. Research suggests that COMT haplotypes exert differential effects on cognition. We sought to investigate differences in the genetic...
The Effect of Convective Injection of Ice on Stratospheric Water Vapor in a Changing Climate
Abstract: Stratospheric water vapor affects the Earth's radiative balance and stratospheric chemistry, yet its future changes are uncertain and not fully understood. The influence of deep convection on stratospheric water vapor...
Flu transcription captured in action.
Aartjan JW Te Velthuis
Jun 25, 2019
Viral mRNA synthesis is an essential step in the influenza virus replication cycle and is a prime target for the development of new antivirals. New structures of the influenza virus RNA polymerase now unveil previously unknown...
Common and unique features of viral RNA-dependent polymerases.
Aartjan JW Te Velthuis
Jul 30, 2018
Eukaryotes and bacteria can be infected with a wide variety of RNA viruses. On average, these pathogens share little sequence similarity and use different replication and transcription strategies. Nevertheless, the members of...
Initiation, Elongation, and Realignment during Influenza Virus mRNA Synthesis.
The RNA-dependent RNA polymerase (RdRp) of the influenza A virus replicates and transcribes the viral genome segments in the nucleus of the host cell. To transcribe these viral genome segments, the RdRp "snatches" capped RNA...
A physiological increase in maternal cortisol alters uteroplacental metabolism in the pregnant ewe.
KEY POINTS: Fetal nutrient supply is dependent, in part, upon the transport capacity and metabolism of the placenta. The stress hormone, cortisol, alters metabolism in the adult and fetus but it is not known whether cortisol in...
Failure of hospital employees to comply with smoke-free policy is associated with nicotine dependence and motives for smoking
Abstract Background Smoke-free policy aims to protect the health of the population by reducing exposure to environmental tobacco smoke (ETS), and World Health Organisation (WHO) guidance notes that these policies are only...
Tobacco Substance Misuse Drug Abuse (NIDA only) Cancer Tobacco Smoke and Health Prevention Clinical Research 3.1 Primary prevention interventions to modify behaviours or promote wellbeing 3 Prevention of disease and conditions and promotion of well-being Cardiovascular Cancer stroke 3 Good Health and Well Being Adult Cross-Sectional Studies Female Guideline Adherence Humans Male Middle Aged Organizational Policy Personnel hospital Surveys and Questionnaires Tobacco Use Disorder United Kingdom
General Approach for Multireference Ground and Excited States Using Nonorthogonal Configuration Interaction.
A balanced description of ground and excited states is essential for the description of many chemical processes. However, few methods can handle cases where static correlation is present, and often these scale very unfavorably...
Reaching Full Correlation through Nonorthogonal Configuration Interaction
Nonorthogonal multireference methods can predict statically correlated adiabatic energies while providing chemical insight through the combination of diabatic reference states. However, reaching quantitative accuracy using...
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