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Interview with Jai Lee
Jai Lee
Jan 01, 0001
In her January 14, 2014 interview with Cody Willis, Jai Lee shares her experience as an economic major from Korea. Lee discusses the differences between Korean colleges and Winthrop. This interview was conducted for inclusion...
Published by: Winthrop University
Stock prices as a leading indicator of the East Asian financial crisis
Using a basic monetary model, we assess the effectiveness of stock prices as a leading indicator of the East Asian currency crisis in 1997 and 1998. Stock prices are incorporated into a monetary model, through the wealth effect...
Stock prices as a leading indicator of the East Asian financial crisis
Using a basic monetary model, we assess the effectiveness of stock prices as a leading indicator of the East Asian currency crisis in 1997 and 1998. Stock prices are incorporated into a monetary model, through the wealth effect...
The Ursinus Weekly, February 16, 1925
Men's debating teams gain two more victories Lebanon Valley alumni hold annual meeting Girls' and men's varsity teams have successful week Zwing anniversary plays selected Founders' Day program has Dr. Broome as speaker ...
Ursinus College Collegeville Pennsylvania newspaper Basketball debate team Elizabeth B. White YMCA YWCA Schaff literary society Zwinglian literary society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology
James Neuberger, Jai Patel, Helen Caldwell, Susan Davies, Vanessa Hebditch, Coral Hollywood, Stefan Hubscher, Salil Karkhanis, Will Lester, Nicholas Roslund, Rebecca West, Judith I Wyatt, Mathis Heydtman
Jun 01, 2020
Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes. There are several approaches to liver biopsy...
Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology.
James Neuberger, Jai Patel, Helen Caldwell, Susan Davies, Vanessa Hebditch, Coral Hollywood, Stefan Hubscher, Salil Karkhanis, Will Lester, Nicholas Roslund, Rebecca West, Judith I Wyatt, Mathis Heydtmann
Jun 03, 2020
Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes. There are several approaches to liver biopsy...
Histopathology interventional radiology liver biopsy Antibiotic Prophylaxis Anticoagulants Biopsy Blood Coagulation Tests Contraindications Procedure Endoscopic Ultrasound-Guided Fine Needle Aspiration Humans Informed Consent Interdisciplinary Communication laparoscopy Liver Needles Patient Selection Postoperative care Professional Role
Integrative Neuroinformatics for Precision Prognostication and Personalized Therapeutics in Moderate and Severe Traumatic Brain Injury.
Frederick A Zeiler, Yasser Iturria-Medina, Eric P Thelin, Alwyn Gomez, Jai J Shankar, Ji Hyun Ko, Chase R Figley, Galen EB Wright, Chris M Anderson
Sep 21, 2021
Despite changes in guideline-based management of moderate/severe traumatic brain injury (TBI) over the preceding decades, little impact on mortality and morbidity have been seen. This argues against the "one-treatment fits all"...
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
Roland Jäger, Gabriele Migliorini, Marc Henrion, Radhika Kandaswamy, Helen E Speedy, Andreas Heindl, Nicola Whiffin, Maria J Carnicer, Laura Broome, Nicola Dryden, Takashi Nagano, Stefan Schoenfelder, Martin Enge, Yinyin Yuan, Jussi Taipale, Peter Fraser, Olivia Fletcher, Richard S Houlston
Jul 15, 2019
Multiple regulatory elements distant from their targets on the linear genome can influence the expression of a single gene through chromatin looping. Chromosome conformation capture implemented in Hi-C allows for genome-wide...
Identification of amino acids within norovirus polymerase involved in RNA binding and viral replication.
Kang Rok Han, Bader Y Alhatlani, Sunyoung Cho, Ji-Hye Lee, Myra Hosmillo, Ian G Goodfellow, Kyung Hyun Kim, Jai Myung Yang
Aug 03, 2017
The different catalytic roles of the metal- binding ligands in human 4-hydroxyphenylpyruvate dioxygenase
Chih-Wei Huang, Hsiu-Chen Liu, Chia-Pei Shen, Yi-Tong Chen, Sung-Jai Lee, Matthew D. Lloyd, Hwei-Jen Lee
May 01, 2016
4‐Hydroxylphenylpyruvatedioxygenase (HPPD) is a non‐haem iron(II)‐dependent oxygenase that catalyzes the conversion of 4‐hydroxylphenylpyruvate (HPP) to homogentisate (HG). In the active site, a strictly conserved 2‐His‐1‐Glu...
The Ursinus Weekly, February 24, 1930
Dr. Leich presents impressive chapel talk Juniata captures debate on Kellogg Pact question Impressive Color Day ceremony by WSGA Men debaters achieve win over Susquehanna Ursinus wrestling team loses to Temple matmen Male...
Ursinus College Collegeville Pennsylvania newspaper Freeland Hall Fire YMCA YWCA Frederick Leich wrestling student government debate team Basketball Edwin C. Broome cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT)
Donna Maria Coleston-Shields, David Challis, Angela Worden, Emma Broome, Tom Dening, Boliang Guo, Juanita Hoe, Brynmor Lloyd-Evans, Esme Moniz-Cook, Steve Morris, Fiona Poland, David Prothero, Martin Orrell
Feb 19, 2022
BACKGROUND: Improving care at home for people with dementia is a core policy goal in the dementia strategies of many European countries. A challenge to effective home support is the occurrence of crises in the care of people...
Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT)
Donna Maria Coleston-Shields, David Challis, Angela Worden, Emma Broome, Tom Dening, Boliang Guo, Juanita Hoe, Brynmor Lloyd-Evans, Esme Moniz-Cook, Steve Morris, Fiona Poland, David Prothero, Martin Orrell
Jan 28, 2022
BACKGROUND: Improving care at home for people with dementia is a core policy goal in the dementia strategies of many European countries. A challenge to effective home support is the occurrence of crises in the care of people...
The different catalytic roles of the metal- binding ligands in human 4-hydroxyphenylpyruvate dioxygenase
Chih-Wei Huang, Hsiu-Chen Liu, Chia-Pei Shen, Yi-Tong Chen, Sung-Jai Lee, Matthew D. Lloyd, Hwei-Jen Lee
May 01, 2016
4‐Hydroxylphenylpyruvatedioxygenase (HPPD) is a non‐haem iron(II)‐dependent oxygenase that catalyzes the conversion of 4‐hydroxylphenylpyruvate (HPP) to homogentisate (HG). In the active site, a strictly conserved 2‐His‐1‐Glu...
IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis.
Rasmus Siersbaek, Valentina Scabia, Sankari Nagarajan, Igor Chernukhin, Evangelia K Papachristou, Rebecca Broome, Simon J Johnston, Stacey EP Joosten, Andrew R Green, Sanjeev Kumar, Julia Jones, Soleilmane Omarjee, Ruben Alvarez-Fernandez, Silvia Glont, Sarah J Aitken, Kamal Kishore, Danya Cheeseman, Emad A Rakha, Clive D'Santos, Wilbert Zwart, Alasdair Russell, Cathrin Brisken, Jason S Carroll
Jul 24, 2020
The cytokine interleukin-6 (IL6) and its downstream effector STAT3 constitute a key oncogenic pathway, which has been thought to be functionally connected to estrogen receptor α (ER) in breast cancer. We demonstrate that...
FOXA1 IL6 STAT3 Breast Cancer estrogen receptor metastasis mouse intraductal xenograft model pioneer factor Animals Antineoplastic Agents Hormonal Breast Neoplasms Enhancer Elements Genetic Estrogen Receptor alpha Female Fulvestrant Gene Expression Profiling Gene Expression Regulation Neoplastic Humans Interleukin-6 Kaplan-Meier Estimate MCF-7 Cells Mice Inbred NOD Mice Knockout Mice SCID Neoplasm Metastasis STAT3 Transcription Factor Signal Transduction Xenograft Model Antitumor Assays
Development and Validation of a Nonremission Risk Prediction Model in First-Episode Psychosis
Samuel P Leighton, Rajeev Krishnadas, Rachel Upthegrove, Steven Marwaha, Ewout W Steyerberg, Georgios V Gkoutos, Matthew R Broome, Peter F Liddle, Linda Everard, Swaran P Singh, Nicholas Freemantle, David Fowler, Peter B Jones, Vimal Sharma, Robin Murray, Til Wykes, Richard J Drake, Iain Buchan, Simon Rogers, Jonathan Cavanagh, Shon W Lewis, Max Birchwood, Pavan K Mallikarjun
Oct 28, 2021
Psychosis is a major mental illness with first onset in young adults. The prognosis is poor in around half of the people affected, and difficult to predict. The few tools available to predict prognosis have major weaknesses...
Schizophrenia Prognosis logistic regression Early intervention Psychotic Disorders Precision Medicine
Published by: Schizophrenia bulletin open
Development and Validation of a Nonremission Risk Prediction Model in First-Episode Psychosis
Samuel P Leighton, Rajeev Krishnadas, Rachel Upthegrove, Steven Marwaha, Ewout W Steyerberg, Georgios V Gkoutos, Matthew R Broome, Peter F Liddle, Linda Everard, Swaran P Singh, Nicholas Freemantle, David Fowler, Peter B Jones, Vimal Sharma, Robin Murray, Til Wykes, Richard J Drake, Iain Buchan, Simon Rogers, Jonathan Cavanagh, Shon W Lewis, Max Birchwood, Pavan K Mallikarjun
Sep 23, 2021
Psychosis is a major mental illness with first onset in young adults. The prognosis is poor in around half of the people affected, and difficult to predict. The few tools available to predict prognosis have major weaknesses...
Development and validation of multivariable prediction models of remission, recovery, and quality of life outcomes in people with first episode psychosis
Samuel P Leighton, Rachel Upthegrove, Rajeev Krishnadas, Michael E Benros, Matthew R Broome, Georgios V Gkoutos, Peter F Liddle, Swaran P Singh, Linda Everard, Peter B Jones, David Fowler, Vimal Sharma, Nicholas Freemantle, Rune HB Christensen, Nikolai Albert, Merete Nordentoft, Matthias Schwannauer, Jonathan Cavanagh, Andrew I Gumley, Max Birchwood, Pavan K Mallikarjun
Sep 23, 2019
A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.
D Beck, JAI Thoms, C Palu, T Herold, A Shah, J Olivier, L Boelen, Y Huang, D Chacon, A Brown, M Babic, C Hahn, M Perugini, X Zhou, BJ Huntly, A Schwarzer, J-H Klusmann, WE Berdel, B Wörmann, T Büchner, W Hiddemann, SK Bohlander, LB To, HS Scott, ID Lewis, RJ D'Andrea, JWH Wong, JE Pimanda
Nov 30, 2017
Prognostic gene expression signatures have been proposed as clinical tools to clarify therapeutic options in acute myeloid leukemia (AML). However, these signatures rely on measuring large numbers of genes and often perform...
Identification of cis-regulatory elements in the upstream regions of zebrafish runx3 gene through an in silico analysis
RUNX3 encodes a member of the runt domain family of transcription factors. In mammals this family includes three genes (RUNX1-3) and their protein products function as context-dependent transcription factors, either...
RUNX3 encodes a member of the runt domain family of transcription factors. In mammals this family includes three genes (RUNX1-3) and their protein products function as context-dependent transcription factors, either...
Identification of cis-regulatory elements in the upstream regions of zebrafish runx3 gene through an in silico analysis
RUNX3 encodes a member of the runt domain family of transcription factors. In mammals this family includes three genes (RUNX1-3) and their protein products function as context-dependent transcription factors, either...
RUNX3 encodes a member of the runt domain family of transcription factors. In mammals this family includes three genes (RUNX1-3) and their protein products function as context-dependent transcription factors, either...
Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia.
Nandor Gabor Than, Roberto Romero, Adi Laurentiu Tarca, Katalin Adrienna Kekesi, Yi Xu, Zhonghui Xu, Kata Juhasz, Gaurav Bhatti, Ron Joshua Leavitt, Zsolt Gelencser, Janos Palhalmi, Tzu Hung Chung, Balazs Andras Gyorffy, Laszlo Orosz, Amanda Demeter, Anett Szecsi, Eva Hunyadi-Gulyas, Zsuzsanna Darula, Attila Simor, Katalin Eder, Szilvia Szabo, Vanessa Topping, Haidy El-Azzamy, Christopher LaJeunesse, Andrea Balogh, Gabor Szalai, Susan Land, Olga Torok, Zhong Dong, Ilona Kovalszky, Andras Falus, Hamutal Meiri, Sorin Draghici, Sonia S Hassan, Tinnakorn Chaiworapongsa, Manuel Krispin, Martin Knöfler, Offer Erez, Graham J Burton, Chong Jai Kim, Gabor Juhasz, Zoltan Papp
Nov 21, 2018
Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our understanding of the complex interactions among their respective disease pathways preclude successful treatment and prevention. The placenta has a...
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Brad H Rovin, Sharon G Adler, Jonathan Barratt, Frank Bridoux, Kelly A Burdge, Tak Mao Chan, H Terence Cook, Fernando C Fervenza, Keisha L Gibson, Richard J Glassock, David RW Jayne, Vivekanand Jha, Adrian Liew, Zhi-Hong Liu, Juan M Mejía-Vilet, Carla M Nester, Jai Radhakrishnan, Elizabeth M Rave, Heather N Reich, Pierre Ronco, Jan-Stephan F Sanders, Sanjeev Sethi, Yusuke Suzuki, Sydney CW Tang, Vladimír Tesar, Marina Vivarelli, Jack FM Wetzels, Lyubov Lytvyn, Jonathan C Craig, David J Tunnicliffe, Martin Howell, Marcello A Tonelli, Michael Cheung, Amy Earley, Jürgen Floege
Nov 10, 2021
The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for the Management of Glomerular Diseases is an update to the KDIGO 2012 guideline. The aim is to assist clinicians caring for individuals with...
AAV ANCA C3 FSGS IgA nephropathy IgA Vasculitis KDIGO MPGN anti-GBM complement evidence-based glomerular diseases glomerulonephritis Guideline infection-related glomerulonephritis Lupus Nephritis membranous nephropathy minimal change disease Nephrotic syndrome Systematic review Adult Child glomerulonephritis glomerulonephritis IGA glomerulonephritis Membranous Humans Kidney Nephrosis Lipoid
Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020.
Craig P Thompson, Nicholas E Grayson, Robert S Paton, Jai S Bolton, José Lourenço, Bridget S Penman, Lian N Lee, Valerie Odon, Juthathip Mongkolsapaya, Senthil Chinnakannan, Wanwisa Dejnirattisai, Matthew Edmans, Alex Fyfe, Carol Imlach, Kreepa Kooblall, Nicholas Lim, Chang Liu, César López-Camacho, Carol McInally, Anna L McNaughton, Narayan Ramamurthy, Jeremy Ratcliff, Piyada Supasa, Oliver Sampson, Beibei Wang, Alexander J Mentzer, Marc Turner, Malcolm G Semple, Kenneth Baillie, ISARIC4C investigators, Heli Harvala, Gavin R Screaton, Nigel Temperton, Paul Klenerman, Lisa M Jarvis, Sunetra Gupta, Peter Simmonds
Jan 18, 2021
BackgroundThe progression and geographical distribution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United Kingdom (UK) and elsewhere is unknown because typically only symptomatic individuals...
Covid19 SARS-CoV-2 pandemic serology SURVEILLANCE Scotland Adult Antibodies Neutralizing Antibodies Viral Betacoronavirus Blood Donors covid-19 Cluster Analysis Coronavirus Infections Enzyme-Linked Immunosorbent Assay Female Geography Medical Humans Inhibitory Concentration 50 Male Models Immunological Neutralization Tests Pandemics Pneumonia Viral Population Surveillance prevalence SARS-CoV-2 Scotland Sensitivity and Specificity Seroepidemiologic Studies Urban Population
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
Richa Saxena, Danish Saleheen, Latonya F Been, Martha L Garavito, Timothy Braun, Andrew Bjonnes, Robin Young, Weang Kee Ho, Asif Rasheed, Philippe Frossard, Xueling Sim, Neelam Hassanali, Venkatesan Radha, Manickam Chidambaram, Samuel Liju, Simon D Rees, Daniel Peng-Keat Ng, Tien-Yin Wong, Toshimasa Yamauchi, Kazuo Hara, Yasushi Tanaka, Hiroshi Hirose, Mark I McCarthy, Andrew P Morris, DIAGRAM, MuTHER, AGEN, Abdul Basit, Anthony H Barnett, Prasad Katulanda, David Matthews, Viswanathan Mohan, Gurpreet S Wander, Jai Rup Singh, Narinder K Mehra, Sarju Ralhan, M Ilyas Kamboh, John J Mulvihill, Hiroshi Maegawa, Kazuyuki Tobe, Shiro Maeda, Yoon S Cho, E Shyong Tai, M Ann Kelly, John C Chambers, Jaspal S Kooner, Takashi Kadowaki, Panos Deloukas, Daniel J Rader, John Danesh, Dharambir K Sanghera
Jun 11, 2018
We performed a genome-wide association study (GWAS) and a multistage meta-analysis of type 2 diabetes (T2D) in Punjabi Sikhs from India. Our discovery GWAS in 1,616 individuals (842 case subjects) was followed by in silico...
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