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Improved EEG source localization with Bayesian uncertainty modelling of unknown skull conductivity
Electroencephalography (EEG) source imaging is an ill-posed inverse problem that requires accurate conductivity modelling of the head tissues, especially the skull. Unfortunately, the conductivity values are difficult to...
Improved EEG source localization with Bayesian uncertainty modelling of unknown skull conductivity
Electroencephalography (EEG) source imaging is an ill-posed inverse problem that requires accurate conductivity modelling of the head tissues, especially the skull. Unfortunately, the conductivity values are difficult to...
Global biogeographic patterns in bipolar moss species.
A bipolar disjunction is an extreme, yet common, biogeographic pattern in non-vascular plants, yet its underlying mechanisms (vicariance or long-distance dispersal), origin and timing remain poorly understood. Here, combining a...
BioVerbNet
Olga Majewska, Charlotte Collins, Simon Baker, Jari Björne, Susan Windisch Brown, Anna Korhonen, Martha Palmer
Aug 16, 2021
Background
Recent advances in representation learning have enabled large strides in natural language understanding; However, verbal reasoning remains a challenge for state-of-the-art systems. External sources of...
Published by: Journal of biomedical semantics
Severe mood disorders and schizophrenia in the adult offspring of antenatally depressed mothers in the Northern Finland 1966 Birth Cohort
BACKGROUND: Maternal antenatal depression may alter offspring neurodevelopment, but long follow-up studies are lacking. We studied the risks for mood disorders and schizophrenia in adult offspring of antenatally depressed...
Antenatal Bipolar Disorder Depression Mood Disorders Parental mental disorder Schizophrenia Adolescent Adult Adult Children Child Child of Impaired Parents Cohort Studies Depressive Disorder Female Finland Follow-Up Studies Humans Mood Disorders Mother-Child Relations Mothers Pregnancy Pregnancy Complications Prenatal Diagnosis Schizophrenic Psychology Young Adult
Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila.
We use the myotendinous junction of Drosophila flight muscles to explore why many integrin associated proteins (IAPs) are needed and how their function is coordinated. These muscles revealed new functions for IAPs not required...
D. melanogaster Actin Cytoskeleton Cell Biology cell-ECM adhesion developmental biology filamin integrin myotendinous junction Vinculin Actins Animals Drosophila Proteins Drosophila melanogaster Epistasis Genetic Flight Animal Integrins Muscles Mutation Myofibrils Phenotype RNA Interference Sarcomeres Vinculin
BioVerbNet
Olga Majewska, Charlotte Collins, Simon Baker, Jari Björne, Susan Windisch Brown, Anna Korhonen, Martha Palmer
Jul 16, 2021
BACKGROUND: Recent advances in representation learning have enabled large strides in natural language understanding; However, verbal reasoning remains a challenge for state-of-the-art systems. External sources of structured...
Prognostic performance of computerized tomography scoring systems in civilian penetrating traumatic brain injury
Matias Lindfors, Caroline Lindblad, David W Nelson, Bo-Michael Bellander, Jari Siironen, Rahul Raj, Eric P Thelin
Oct 27, 2020
A novel sweet potato potyvirus open reading frame (ORF) is expressed via polymerase slippage and suppresses RNA silencing.
Milton Untiveros, Allan Olspert, Katrin Artola, Andrew E Firth, Jan F Kreuze, Jari PT Valkonen
Dec 22, 2015
RNA silencing suppression RNA virus frameshift Gene Expression overlapping gene transcriptional slippage Amino Acid Motifs Amino Acid Sequence Base Sequence DNA-Directed RNA Polymerases Genes Suppressor Genetic Vectors Genome Viral Genomics High-Throughput Nucleotide Sequencing Ipomoea batatas Mutation Open Reading Frames Peptides Phenotype Polymorphism Single Nucleotide Potyvirus RNA Interference RNA Viral Structure-Activity Relationship SUPPRESSION Genetic Transcription Genetic Viral Proteins
Standalone sauna vs exercise followed by sauna on cardiovascular function in non-naïve sauna users
Earric Lee, Joel Kostensalo, Peter Willeit, Setor K Kunutsor, Tanjaniina Laukkanen, Francesco Zaccardi, Hassan Khan, Jari A Laukkanen
Oct 01, 2021
BACKGROUND AND AIMS: Sauna bathing and aerobic exercise have each been shown to affect cardiovascular function. However, direct comparisons between standalone sauna bathing and a combination of exercise and sauna on vascular...
Cytokinin and Auxin Display Distinct but Interconnected Distribution and Signaling Profiles to Stimulate Cambial Activity.
Juha Immanen, Kaisa Nieminen, Olli-Pekka Smolander, Mikiko Kojima, Juan Alonso Serra, Patrik Koskinen, Jing Zhang, Annakaisa Elo, Ari Pekka Mähönen, Nathaniel Street, Rishikesh P Bhalerao, Lars Paulin, Petri Auvinen, Hitoshi Sakakibara, Ykä Helariutta
Jun 23, 2016
BioVerbNet
Olga Majewska, Charlotte Collins, Simon Baker, Jari Björne, Susan Windisch Brown, Anna Korhonen, Martha Palmer
Jul 28, 2021
Abstract: Background: Recent advances in representation learning have enabled large strides in natural language understanding; However, verbal reasoning remains a challenge for state-of-the-art systems. External sources of...
Longitudinal associations of physical activity, sedentary time, and cardiorespiratory fitness with arterial health in children - the PANIC study.
Marika Korhonen, Juuso Väistö, Aapo Veijalainen, Marja Leppänen, Ulf Ekelund, Jari A Laukkanen, Soren Brage, Niina Lintu, Eero A Haapala, Timo A Lakka
May 03, 2021
We investigated the longitudinal associations of physical activity (PA), sedentary time (ST), and cardiorespiratory fitness (CRF) with arterial health among children. In our primary analyses, we investigated 245 children (girls...
Comparison of high versus low frequency cerebral physiology for cerebrovascular reactivity assessment in traumatic brain injury
Eric P Thelin, Rahul Raj, Bo-Michael Bellander, David Nelson, Anna Piippo-Karjalainen, Jari Siironen, Päivi Tanskanen, Gregory Hawryluk, Mohammed Hasen, Bertram Unger, Frederick A Zeiler
Sep 25, 2019
Current accepted cerebrovascular reactivity indices suffer from the need of high frequency data capture and export for post-acquisition processing. The role for minute-by-minute data in cerebrovascular reactivity monitoring...
Evaluation of novel computerized tomography scoring systems in human traumatic brain injury
Eric Peter Thelin, David W Nelson, Juho Vehviläinen, Harriet Nyström, Riku Kivisaari, Jari Siironen, Mikael Svensson, Markus B Skrifvars, Bo-Michael Bellander, Rahul Raj
Dec 11, 2017
BACKGROUND: Traumatic brain injury (TBI) is a major contributor to morbidity and mortality. Computerized tomography (CT) scanning of the brain is essential for diagnostic screening of intracranial injuries in need of...
Comparison of high versus low frequency cerebral physiology for cerebrovascular reactivity assessment in traumatic brain injury
Eric P. Thelin, Rahul Raj, Bo-Michael Bellander, David Nelson, Anna Piippo-Karjalainen, Jari Siironen, Päivi Tanskanen, Gregory Hawryluk, Mohammed Hasen, Bertram Unger, Frederick A. Zeiler
Sep 30, 2020
Abstract: Current accepted cerebrovascular reactivity indices suffer from the need of high frequency data capture and export for post-acquisition processing. The role for minute-by-minute data in cerebrovascular reactivity...
Comparison of high versus low frequency cerebral physiology for cerebrovascular reactivity assessment in traumatic brain injury
Eric P. Thelin, Rahul Raj, Bo-Michael Bellander, David Nelson, Anna Piippo-Karjalainen, Jari Siironen, Päivi Tanskanen, Gregory Hawryluk, Mohammed Hasen, Bertram Unger, Frederick A. Zeiler
Aug 25, 2020
Abstract: Current accepted cerebrovascular reactivity indices suffer from the need of high frequency data capture and export for post-acquisition processing. The role for minute-by-minute data in cerebrovascular reactivity...
Longitudinal association between CRP levels and risk of psychosis
Emanuele F. Osimo, Luke Baxter, Jan Stochl, Benjamin I. Perry, Stephen A. Metcalf, Setor K. Kunutsor, Jari A. Laukkanen, Marie Kim Wium-Andersen, Peter B. Jones, Golam M. Khandaker
May 28, 2021
Abstract: Meta-analyses of cross-sectional studies suggest that patients with psychosis have higher circulating levels of C-reactive protein (CRP) compared with healthy controls; however, cause and effect is unclear. We examined...
Creation of a library of induced pluripotent stem cells from Parkinsonian patients.
Staffan Holmqvist, Šárka Lehtonen, Margarita Chumarina, Katja A Puttonen, Carla Azevedo, Olga Lebedeva, Marika Ruponen, Minna Oksanen, Mehdi Djelloul, Anna Collin, Stefano Goldwurm, Morten Meyer, Maria Lagarkova, Sergei Kiselev, Jari Koistinaho, Laurent Roybon
Jun 01, 2020
Induced pluripotent stem cells (iPSCs) are becoming an important source of pre-clinical models for research focusing on neurodegeneration. They offer the possibility for better understanding of common and divergent pathogenic...
Genetics Stem Cell Research - Induced Pluripotent Stem Cell - Human aging ALS Parkinson's Disease Stem Cell Research - Induced Pluripotent Stem Cell Brain Disorders Rare Diseases Acquired Cognitive Impairment Stem Cell Research Neurodegenerative Dementia Neurosciences Clinical Research 2.1 Biological and endogenous factors 2 Aetiology Neurological
Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, Christel Reuterswärd, Anna Karlsson, Shamik Mitra, Emma Niméus, Karolina Holm, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Christer Larsson, Martin Malmberg, Lisa Rydén, Anna Ehinger, Niklas Loman, Anders Kvist, Hans Ehrencrona, Serena Nik-Zainal, Åke Borg, Johan Staaf
Jul 27, 2020
Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, Christel Reuterswärd, Anna Karlsson, Shamik Mitra, Emma Niméus, Karolina Holm, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Christer Larsson, Martin Malmberg, Lisa Rydén, Anna Ehinger, Niklas Loman, Anders Kvist, Hans Ehrencrona, Serena Nik-Zainal, Åke Borg, Johan Staaf
Jul 28, 2021
Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder
Atiqul Haq Mazumder, Jennifer Barnett, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Jarmo Hietala, Erkki Isometsä, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Solja Niemelä, Jari Tiihonen, Tiina Paunio, Aarno Palotie, Jaana Suvisaari, Juha Veijola
May 24, 2021
The purpose of this study was to explore the association between cognition and hazardous drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognition is more or less compromised in schizophrenia...
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