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Results: 1362
Teachers "Finding Peace in a Frantic World"
Jesus Montero-Marin, Laura Taylor, Catherine Crane, Mark T Greenberg, Tamsin J Ford, J Mark G Williams, Javier García-Campayo, Anna Sonley, Liz Lord, Tim Dalgleish, Sarah-Jayne Blakemore, MYRIAD team, Willem Kuyken
Jan 28, 2022
Mindfulness training (MT) is considered appropriate for school teachers and enhances well-being. Most research has investigated the efficacy of instructor-led MT. However, little is known about the benefits of using self-taught...
An Empirical Analysis of Trust, Perceived Benefit, and Purchase Intention in C2C Electronic Commerce in China
Jin Liang, Javier Garcia-Campayo, Zhongwei Wang, Hector Perez, Huaqiang Li, Luis Borao, Yantao Yang, Zijian Zhao
Mar 09, 2023
With the popularity and development of the internet, China's consumer-to-consumer (C2C) electronic commerce (EC) system is favored by consumers. Therefore, understanding the relationship among consumers' trust, perceived...
Published by: IGI Global Scientific Publishing
Transforming students' attitudes towards learning through the use of successful educational actions.
Previous research shows that there is a correlation between attitudes and academic achievement. In this article, we analyze for the first time the impact of interactive groups (IG) and dialogic literary gatherings (DLG) on the...
Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.
Sara Ruiz-Pinto, Guillermo Pita, Miguel Martín, Teresa Alonso-Gordoa, Daniel R Barnes, María R Alonso, Belén Herraez, Purificación García-Miguel, Javier Alonso, Antonio Pérez-Martínez, Antonio J Cartón, Federico Gutiérrez-Larraya, José A García-Sáenz, Javier Benítez, Douglas F Easton, Ana Patiño-García, Anna González-Neira
Jan 30, 2018
PURPOSE: Anthracyclines are widely used chemotherapeutic drugs that can cause progressive and irreversible cardiac damage and fatal heart failure. Several genetic variants associated with anthracycline-induced cardiotoxicity...
Anthracyclines Chronic cardiotoxicity ETFB Long-term cancer survivors Low-frequency variants Adult Aged Anthracyclines Breast Neoplasms Cancer Survivors Cardiotoxicity Electron-Transferring Flavoproteins Exome Female Gene Expression Regulation Neoplastic Genetic Association Studies Genetic Predisposition to Disease Heart Failure Humans Middle Aged Mitochondria
Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly.
Kevin N Baumann, Luca Piantanida, Javier García-Nafría, Diana Sobota, Kislon Voïtchovsky, Tuomas PJ Knowles, Silvia Hernández-Ainsa
May 29, 2020
The self-assembly of the protein clathrin on biological membranes facilitates essential processes of endocytosis and has provided a source of inspiration for materials design by the highly ordered structural appearance. By...
Phosphoinositide 3-kinase beta controls replication factor C assembly and function.
Javier Redondo-Muñoz, María Josefa Rodríguez, Virginia Silió, Vicente Pérez-García, José María Valpuesta, Ana C Carrera
Apr 16, 2019
Genomic integrity is preserved by the action of protein complexes that control DNA homeostasis. These include the sliding clamps, trimeric protein rings that are arranged around DNA by clamp loaders. Replication factor C (RFC)...
Deciphering Master Gene Regulators and Associated Networks of Human Mesenchymal Stromal Cells.
Elena Sánchez-Luis, Andrea Joaquín-García, Francisco J Campos-Laborie, Fermín Sánchez-Guijo, Javier De Las Rivas
Jun 22, 2020
Mesenchymal Stromal Cells (MSC) are multipotent cells characterized by self-renewal, multilineage differentiation, and immunomodulatory properties. To obtain a gene regulatory profile of human MSCs, we generated a compendium of...
Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes.
Andrés García-García, Claudia Korn, María García-Fernández, Olivia Domingues, Javier Villadiego, Daniel Martín-Pérez, Joan Isern, José A Bejarano-García, Jacques Zimmer, José A Pérez-Simón, Juan J Toledo-Aral, Tatiana Michel, Matti S Airaksinen, Simón Méndez-Ferrer
Dec 07, 2018
Hematopoietic stem and progenitor cells (HSPCs) and leukocytes circulate between the bone marrow (BM) and peripheral blood following circadian oscillations. Autonomic sympathetic noradrenergic signals have been shown to regulate...
Animals Bone Marrow Cells Cell Adhesion Cell Movement Cells Cultured Chemotaxis Cholinergic Agents Circadian Rhythm Endothelium Vascular Female Glial Cell Line-Derived Neurotrophic Factor Receptors Hematopoietic Stem Cells Leukocytes Male Mice Mice Inbred C57BL Mice Knockout Parasympathetic Nervous System Receptors Adrenergic beta-2 Receptors Adrenergic beta-3 Receptors G-Protein-Coupled sympathetic nervous system
Evolution of a Relativistic Outflow and X-Ray Corona in the Extreme Changing-look AGN 1ES 1927+654
Abstract
1ES 1927+654 is a paradigm-defying active galactic nucleus (AGN) and one of the most peculiar X-ray nuclear transients. In early 2018, this well-known AGN underwent a...
Megan Masterson, Erin Kara, Claudio Ricci, Javier A García, Andrew C Fabian, Ciro Pinto, Peter Kosec, Ronald A Remillard, Michael Loewenstein, Benny Trakhtenbrot, Iair Arcavi
Jul 22, 2022
ROS-Scavenging Enzymes as an Antioxidant Response to High Concentration of Anthracene in the Liverwort Marchantia polymorpha L
Nahuel Spinedi, Romina Storb, Elisabet Aranda, Facundo Romani, Maya Svriz, Santiago A. Varela, Javier E. Moreno, Sebastian Fracchia, Juan Cabrera, Ramón Alberto Batista-García, Inés Ponce de León, J. Martín Scervino
Jul 28, 2021
Marchantia polymorpha L. responds to environmental changes using a myriad set of physiological responses, some unique to the lineage related to the lack of a vascular- and root-system. This study investigates the physiological...
Relative abundance of the Prevotella genus within the human gut microbiota of elderly volunteers determines the inter-individual responses to dietary supplementation with wheat bran arabinoxylan-oligosaccharides
Wing Sun Faith Chung, Alan W. Walker, Douwina Bosscher, Vicenta Garcia-Campayo, Josef Wagner, Julian Parkhill, Sylvia H. Duncan, Harry J. Flint
Sep 14, 2020
Abstract: Background: The human colon is colonised by a dense microbial community whose species composition and metabolism are linked to health and disease. The main energy sources for colonic bacteria are dietary...
Protease and gag diversity and drug resistance mutations among treatment-naive Mexican people living with HIV.
Samantha Climaco-Arvizu, Víctor Flores-López, Carolina González-Torres, Francisco Javier Gaytán-Cervantes, María Concepción Hernández-García, Paola Berenice Zárate-Segura, Monserrat Chávez-Torres, Emiliano Tesoro-Cruz, Sandra María Pinto-Cardoso, Vilma Carolina Bekker-Méndez
May 10, 2022
INTRODUCTION: In Mexico, HIV genotyping is performed in people living with HIV (PLWH) failing their first-line antiretroviral (ARV) regimen; it is not routinely done for all treatment-naive PLWH before ARV initiation. The first...
Antiretroviral Therapy Gag HIV drug resistance mutations HIV genotyping human immunodeficiency virus Next generation sequencing Protease Adult Anti-HIV Agents Anti-Retroviral Agents Drug Resistance Viral Female Genotype HIV Infections HIV Protease HIV-1 Humans Male Mexico Mutation Peptide Hydrolases Reverse Transcriptase Inhibitors
Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody.
Javier Macías-León, Iris A Bermejo, Alicia Asín, Ana García-García, Ismael Compañón, Ester Jiménez-Moreno, Helena Coelho, Vincenzo Mangini, Inês S Albuquerque, Filipa Marcelo, Juan L Asensio, Gonçalo JL Bernardes, Hiren J Joshi, Roberto Fiammengo, Ola Blixt, Ramón Hurtado-Guerrero, Francisco Corzana
Nov 13, 2020
The molecular basis of antibody 5E5, which recognizes the entire GalNAc unit as a primary epitope is disclosed. The antibody's contacts with the peptide are mostly limited to two residues, allowing it to show some degree of...
ROS-Scavenging Enzymes as an Antioxidant Response to High Concentration of Anthracene in the Liverwort <i>Marchantia polymorpha</i> L.
Nahuel Spinedi, Romina Storb, Elisabet Aranda, Facundo Romani, Maya Svriz, Santiago A Varela, Javier E Moreno, Sebastian Fracchia, Juan Cabrera, Ramón Alberto Batista-García, Inés Ponce de León, J Martín Scervino
Sep 10, 2021
Marchantia polymorpha L. responds to environmental changes using a myriad set of physiological responses, some unique to the lineage related to the lack of a vascular- and root-system. This study investigates the...
Human forager response to abrupt climate change at 8.2 ka on the Atlantic coast of Europe.
Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.
Frank Reimann, C Rubio, , Marta Puerto, Juan J García-Rodríquez, Van B Lu, Irma García-Martínez, Rosa Alén, , Patricia Sanmartín-Salinas, M Val Toledo-Lobo, Jorge Saiz, Javier Ruperez, Coral Barbas, Luis Menchén, Fiona M Gribble, Luis G Guijarro, Jose M Carrascosa, Angela M Valverde
Jan 31, 2020
GLP-1 GLP-2 Gut microbiota Inflammation NASH PTP1B Animals Choline Deficiency Diet Disease Models Animal Gastrointestinal Microbiome Gene Expression Gene Knockout Techniques Glucagon-Like Peptide 1 Inflammation Intestinal Mucosa Liver Male Methionine Mice Mice Inbred C57BL Mice Knockout non-alcoholic fatty liver disease Permeability Protein Tyrosine Phosphatase Non-Receptor Type 1 RAW 264.7 Cells
Relative abundance of the Prevotella genus within the human gut microbiota of elderly volunteers determines the inter-individual responses to dietary supplementation with wheat bran arabinoxylan-oligosaccharides
Wing Sun Faith Chung, Alan W. Walker, Douwina Bosscher, Vicenta Garcia-Campayo, Josef Wagner, Julian Parkhill, Sylvia H. Duncan, Harry J. Flint
Sep 14, 2021
Abstract: Background: The human colon is colonised by a dense microbial community whose species composition and metabolism are linked to health and disease. The main energy sources for colonic bacteria are dietary...
The Impact of Dissonant Tie on Innovation Performance of Digital Transformation
The acquisition of innovation performance through social network relationship resources is a common behavior pattern of organizational members. Recent social network research suggests that negative ties may also have a positive...
Published by: IGI Global Scientific Publishing
ROS-Scavenging Enzymes as an Antioxidant Response to High Concentration of Anthracene in the Liverwort Marchantia polymorpha L.
Nahuel Spinedi, Romina Storb, Elisabet Aranda, Facundo Romani, Maya Svriz, Santiago A Varela, Javier E Moreno, Sebastian Fracchia, Juan Cabrera, Ramón Alberto Batista-García, Inés Ponce de León, J Martín Scervino
Aug 05, 2021
Marchantia polymorpha L. responds to environmental changes using a myriad set of physiological responses, some unique to the lineage related to the lack of a vascular- and root-system. This study investigates the physiological...
Human forager response to abrupt climate change at 8.2 ka on the Atlantic coast of Europe.
Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.
Sara Ruiz-Pinto, Guillermo Pita, Ana Patiño-García, Javier Alonso, Antonio Pérez-Martínez, Antonio J Cartón, Federico Gutiérrez-Larraya, María R Alonso, Daniel R Barnes, Joe Dennis, Kyriaki Michailidou, Carmen Gómez-Santos, Deborah J Thompson, Douglas F Easton, Javier Benítez, Anna González-Neira
Apr 06, 2018
Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.
Carmen Rubio, Marta Puerto, Juan J García-Rodríquez, Van B Lu, Irma García-Martínez, Rosa Alén, Patricia Sanmartín-Salinas, M Val Toledo-Lobo, Jorge Saiz, Javier Ruperez, Coral Barbas, Luis Menchén, Fiona M Gribble, Frank Reimann, Luis G Guijarro, Jose M Carrascosa, Ángela M Valverde
May 05, 2020
OBJECTIVE:Non-alcoholic steatohepatitis (NASH) is characterized by a robust pro-inflammatory component at both hepatic and systemic levels together with a disease-specific gut microbiome signature. Protein tyrosine phosphatase...
Published by: Molecular metabolism
Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma
Esperanza M. Algarín, Dalia Quwaider, Francisco J. Campos-Laborie, Andrea Díaz-Tejedor, Pedro Mogollón, Elena Vuelta, Montserrat Martín-Sánchez, Laura San-Segundo, Lorena González-Méndez, Norma C. Gutiérrez, Ramón García-Sanz, Teresa Paíno, Javier De Las Rivas, Enrique M. Ocio, Mercedes Garayoa
Mar 05, 2021
BH3-mimetics targeting anti-apoptotic proteins such as MCL-1 (S63845) or BCL-2 (venetoclax) are currently being evaluated as effective therapies for the treatment of multiple myeloma (MM). Interleukin 6, produced by mesenchymal...
Evaluation of Methodologies for Assessing Self-Healing Performance of Concrete with Mineral Expansive Agents
Chrysoula Litina, Girts Bumanis, Giovanni Anglani, Marta Dudek, Riccardo Maddalena, Maria Amenta, Stamatoula Papaioannou, Gloria Pérez, José Luis García García Calvo, Eloy Asensio, Rubén Beltrán Cobos, Fabiano Tavares Pinto, Algirdas Augonis, Robert Davies, Ana Guerrero, Mercedes Sánchez Moreno, Teresa Stryszewska, Ioannis Karatasios, Jean-Marc Tulliani, Paola Antonaci, Diana Bajare, Abir Al-Tabbaa
Apr 18, 2021
Self-healing concrete has the potential to optimise traditional design approaches; however, commercial uptake requires the ability to harmonize against standardized frameworks. Within EU SARCOS COST Action, different...
The NICER “Reverberation Machine”
Abstract
We perform the first systematic search of all NICER archival observations of black hole (and candidate) low-mass X-ray binaries for signatures of reverberation....
Jingyi Wang, Erin Kara, Matteo Lucchini, Adam Ingram, Michiel van der Klis, Guglielmo Mastroserio, Javier A García, Thomas Dauser, Riley Connors, Andrew C Fabian, James F Steiner, Ron A Remillard, Edward M Cackett, Phil Uttley, Diego Altamirano
May 02, 2022
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