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Results: 13
Trans-diagnostic measurement of impulsivity and compulsivity
Roxanne W Hook, Jon E Grant, Konstantinos Ioannidis, Jeggan Tiego, Murat Yücel, Paul Wilkinson, Samuel R Chamberlain
Oct 26, 2020
INTRODUCTION: Impulsivity and compulsivity are important constructs, relevant to understanding behaviour in the general population, as well as in particular mental disorders (e.g. attention deficit hyperactivity disorder...
Measurement of the problematic usage of the Internet unidimensional quasitrait continuum with item response theory.
Jeggan Tiego, Christine Lochner, Konstantinos Ioannidis, Matthias Brand, Dan J Stein, Murat Yücel, Jon E Grant, Samuel R Chamberlain
Feb 19, 2021
Problematic usage of the internet (PUI) describes maladaptive use of online resources and is recognized as a growing worldwide issue. Here, we refined the Internet Addiction Test (IAT) for use as a screening tool to measure...
Heritability of overlapping impulsivity and compulsivity dimensional phenotypes.
Jeggan Tiego, Samuel R Chamberlain, Ben J Harrison, Andrew Dawson, Lucy Albertella, George J Youssef, Leonardo F Fontenelle, Murat Yücel
Nov 02, 2020
Impulsivity and compulsivity are traits relevant to a range of mental health problems and have traditionally been conceptualised as distinct constructs. Here, we reconceptualised impulsivity and compulsivity as partially...
Problematic use of the Internet is a unidimensional quasi-trait with impulsive and compulsive subtypes
Jeggan Tiego, Christine Lochner, Konstantinos Ioannidis, Matthias Brand, Dan J. Stein, Murat Yücel, Jon E. Grant, Samuel R. Chamberlain
Nov 09, 2020
Abstract: Background: Problematic use of the Internet has been highlighted as needing further study by international bodies, including the European Union and American Psychiatric Association. Knowledge regarding the optimal...
Problematic use of the Internet is a unidimensional quasi-trait with impulsive and compulsive subtypes.
Jeggan Tiego, Christine Lochner, Konstantinos Ioannidis, Matthias Brand, Dan J Stein, Murat Yücel, Jon E Grant, Samuel R Chamberlain
Nov 01, 2019
BACKGROUND: Problematic use of the Internet has been highlighted as needing further study by international bodies, including the European Union and American Psychiatric Association. Knowledge regarding the optimal classification...
Brain micro-architecture and disinhibition
Rafa Romero-Garcia, Roxanne W Hook, Jeggan Tiego, Richard AI Bethlehem, Ian M Goodyer, Peter B Jones, Ray Dolan, Jon E Grant, Edward T Bullmore, Murat Yücel, Samuel R Chamberlain
Sep 02, 2020
Impulsive and compulsive symptoms are common, tend to co-occur, and collectively account for a substantive global disease burden. Latent phenotyping offers a promising approach to elucidate common neural mechanisms conferring...
Brain micro-architecture and disinhibition
Rafa Romero-Garcia, Roxanne W. Hook, Jeggan Tiego, Richard A. I. Bethlehem, Ian M. Goodyer, Peter B. Jones, Ray Dolan, Jon E. Grant, Edward T. Bullmore, Murat Yücel, Samuel R. Chamberlain
Dec 07, 2020
Abstract: Impulsive and compulsive symptoms are common, tend to co-occur, and collectively account for a substantive global disease burden. Latent phenotyping offers a promising approach to elucidate common neural mechanisms...
Fractionation of impulsive and compulsive trans-diagnostic phenotypes and their longitudinal associations.
Samuel R Chamberlain, Jeggan Tiego, Leonardo F Fontenelle, Roxanne Hook, Linden Parkes, Rebecca Segrave, Tobias U Hauser, Ray J Dolan, Ian M Goodyer, Ed Bullmore, Jon E Grant, Murat Yücel
Apr 05, 2019
OBJECTIVE: Young adulthood is a crucial neurodevelopmental period during which impulsive and compulsive problem behaviours commonly emerge. While traditionally considered diametrically opposed, impulsive and compulsive symptoms...
Brain micro-architecture and disinhibition
Rafa Romero-Garcia, Roxanne W. Hook, Jeggan Tiego, Richard A. I. Bethlehem, Ian M. Goodyer, Peter B. Jones, Ray Dolan, Jon E. Grant, Edward T. Bullmore, Murat Yücel, Samuel R. Chamberlain
Sep 12, 2021
Abstract: Impulsive and compulsive symptoms are common, tend to co-occur, and collectively account for a substantive global disease burden. Latent phenotyping offers a promising approach to elucidate common neural mechanisms...
Transdiagnostic variations in impulsivity and compulsivity in obsessive-compulsive disorder and gambling disorder correlate with effective connectivity in cortical-striatal-thalamic-cortical circuits.
Linden Parkes, Jeggan Tiego, Kevin Aquino, Leah Braganza, Samuel R Chamberlain, Leonardo F Fontenelle, Ben J Harrison, Valentina Lorenzetti, Bryan Paton, Adeel Razi, Alex Fornito, Murat Yücel
Sep 03, 2019
Individual differences in impulsivity and compulsivity is thought to underlie vulnerability to a broad range of disorders and are closely tied to cortical-striatal-thalamic-cortical function. However, whether impulsivity and...
Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study.
Matthias Kirschner, Benazir Hodzic-Santor, Mathilde Antoniades, Igor Nenadic, Tilo Kircher, Axel Krug, Tina Meller, Dominik Grotegerd, Alex Fornito, Aurina Arnatkeviciute, Mark A Bellgrove, Jeggan Tiego, Udo Dannlowski, Katharina Koch, Carina Hülsmann, Harald Kugel, Verena Enneking, Melissa Klug, Elisabeth J Leehr, Joscha Böhnlein, Marius Gruber, David Mehler, Pamela DeRosse, Ashley Moyett, Bernhard T Baune, Melissa Green, Yann Quidé, Christos Pantelis, Raymond Chan, Yi Wang, Ulrich Ettinger, Martin Debbané, Melodie Derome, Christian Gaser, Bianca Besteher, Kelly Diederen, Tom J Spencer, Paul Fletcher, Wulf Rössler, Lukasz Smigielski, Veena Kumari, Preethi Premkumar, Haeme RP Park, Kristina Wiebels, Imke Lemmers-Jansen, James Gilleen, Paul Allen, Petya Kozhuharova, Jan-Bernard Marsman, Irina Lebedeva, Alexander Tomyshev, Anna Mukhorina, Stefan Kaiser, Anne-Kathrin Fett, Iris Sommer, Sanne Schuite-Koops, Casey Paquola, Sara Larivière, Boris Bernhardt, Alain Dagher, Phillip Grant, Theo GM van Erp, Jessica A Turner, Paul M Thompson, André Aleman, Gemma Modinos
Apr 29, 2022
Neuroanatomical abnormalities have been reported along a continuum from at-risk stages, including high schizotypy, to early and chronic psychosis. However, a comprehensive neuroanatomical mapping of schizotypy remains to be...