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The Privileged Life of a Theoretical Observer.
Douglas Gough
Aug 17, 2022
This is a summary of my scientific career, biased by my personal view of events and unashamedly concentrating on those aspects of some of the scientific developments to which I have contributed. A selective unbiased alternative...
The Privileged Life of a Theoretical Observer
Abstract This is a summary of my scientific career, biased by my personal view of events and unashamedly concentrating on those aspects of some of the scientific developments to which I have...
Douglas Gough
Jul 26, 2022
Transient cardiac dysfunction but elevated cardiac and kidney biomarkers 24 h following an ultra-distance running event in Mexican Tarahumara.
Dirk L Christensen, Diana Espino, Rocío Infante-Ramírez, Mónica S Cervantes-Borunda, Rosa P Hernández-Torres, Antonio E Rivera-Cisneros, Daniel Castillo, Kate Westgate, Dijana Terzic, Soren Brage, Christian Hassager, Jens P Goetze, Jesper Kjaergaard
Mar 22, 2018
BACKGROUND: The Mexican Tarahumara are accustomed to running ultra-distance races. No data exist on the acute physiological changes following ultra-distance running and physiological-biomarker associations in this population....
Single-Molecule Studies of CFTR Gating and Pharmacology
Jesper Bøegh Levring
Jan 01, 0001
The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel expressed in the apical membrane of epithelial tissues. Alterations in CFTR that disrupt activity cause cystic fibrosis, a fatal disease which...
Published by: Rockefeller University
Freedom as Ariadne’s Thread through the Interpretation of Life
Jesper L. Rasmussen
Aug 29, 2018
According to Schelling’s 1806 Aphorisms as an Introduction to Naturphilosophie, the aim of philosophy should be nothing less than a sort of excitation of further developments of an eternal poem (Gedicht) (SW VII: 145f). This...
Published by: Memorial University Libraries
Freedom as Ariadne’s Thread through the Interpretation of Life
Jesper L. Rasmussen
Aug 29, 2018
According to Schelling’s 1806 Aphorisms as an Introduction to Naturphilosophie, the aim of philosophy should be nothing less than a sort of excitation of further developments of an eternal poem (Gedicht) (SW VII: 145f). This...
Published by: Memorial University Libraries
Towards resolving the presynaptic NMDA receptor debate.
In the classical view, postsynaptic NMDA receptors (NMDARs) trigger Hebbian plasticity via Ca2+ influx. However, unconventional presynaptic NMDARs (preNMDARs) which regulate both long-term and short-term plasticity at several...
Offsetting the Destruction of Marine Fish Habitat During Coastal Development Projects in Canada
Under the Fisheries Act of Canada (2012), proponents of development projects are responsible for offsetting the destruction of freshwater and marine habitat if “serious harm” is expected to occur to fish supporting a commercial...
ML-SIM
Structured illumination microscopy (SIM) has become an important technique for
optical super-resolution imaging because it allows a doubling of image resolution at speeds
compatible with live-cell imaging. However, the...
Calcium imaging analysis - how far have we come?
Techniques for calcium imaging were first demonstrated in the mid-1970s, whilst tools to analyse these markers of cellular activity are still being developed and improved today. For image analysis, custom tools were developed...
classification Neural Networks Quantification denoising calcium imaging Machine Learning motion correction
Published by: F1000Research
Offsetting the Destruction of Marine Fish Habitat During Coastal Development Projects in Canada
Under the Fisheries Act of Canada (2012), proponents of development projects are responsible for offsetting the destruction of freshwater and marine habitat if “serious harm” is expected to occur to fish supporting a commercial...
Calcium imaging analysis - how far have we come?
Techniques for calcium imaging were first demonstrated in the mid-1970s, whilst tools to analyse these markers of cellular activity are still being developed and improved today. For image analysis, custom tools were developed...
The Grizzly, February 15, 2024
Marie Sykes, Sidney Belleroche, Nicolas Ungurean, Renie Christensen, Mairead McDermott, Dominic Minicozzi, Adam Denn
Jan 01, 0001
Freedom, Transformation and Pathways: Spring Exhibits at the Berman Ursinus Faculty Discusses Generative A.I. An Artist's Craft: The Making of Running Away Everybody Dies Opinions: What Was Your Favorite Memory Studying...
Ursinus College Collegeville Pennsylvania newspaper Berman Art Museum Kukulia Velarde Adriane Colburn Sahar Tarighi Artificial Intelligence Sam Love theater morality play study abroad Basketball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Oesophageal cancer.
Elizabeth C Smyth, Jesper Lagergren, Rebecca C Fitzgerald, Florian Lordick, Manish A Shah, Pernilla Lagergren, David Cunningham
Sep 05, 2018
Oesophageal cancer is the sixth most common cause of cancer-related death worldwide and is therefore a major global health challenge. The two major subtypes of oesophageal cancer are oesophageal squamous cell carcinoma (OSCC)...
Adenocarcinoma Africa Eastern Aged Aged 80 and over Antineoplastic Agents Immunological Carcinoma Squamous Cell Chemoradiotherapy endoscopy Digestive System Esophageal Neoplasms Esophageal Squamous Cell Carcinoma Female Humans Male Middle Aged Prognosis Receptor ErbB-2 South America Survival Rate Trastuzumab Treatment Outcome
Published by: Nat Rev Dis Primers
Broadband criticality of human brain network synchronization.
Self-organized criticality is an attractive model for human brain dynamics, but there has been little direct evidence for its existence in large-scale systems measured by neuroimaging. In general, critical systems are associated...
Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria.
Barney A Geddes, Ponraj Paramasivan, Amelie Joffrin, Amber L Thompson, Kirsten Christensen, Beatriz Jorrin, Paul Brett, Stuart J Conway, Giles ED Oldroyd, Philip S Poole
Sep 10, 2019
The root microbiota is critical for agricultural yield, with growth-promoting bacteria able to solubilise phosphate, produce plant growth hormones, antagonise pathogens and fix N2. Plants control the microorganisms in their...
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