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Genomic risk scores for juvenile idiopathic arthritis and its subtypes
Rodrigo Cánovas, Joanna Cobb, Marta Brozynska, John Bowes, Yun R Li, Samantha Louise Smith, Hakon Hakonarson, Wendy Thomson, Justine A Ellis, Gad Abraham, Jane E Munro, Michael Inouye
Sep 09, 2020
Objectives: Juvenile idiopathic arthritis (JIA) is an autoimmune disease and a common cause of chronic disability in children. Diagnosis of JIA is based purely on clinical symptoms, which can be variable, leading to diagnosis...
90K immunostimulatory glycoprotein in children with juvenile idiopathic arthritis.
Cristina Cecamore, Manuela Marsili, Roberta Salvatore, Roberto Troiani, Maurizia D'Egidio, Nicola Tinari, Piernicola Pelliccia, Francesco Chiarelli, M Loredana Marcovecchio, Luciana Breda
Nov 23, 2018
OBJECTIVES: To assess whether circulating levels of 90K glycoprotein are increased in children with juvenile idiopathic arthritis (JIA) at different stages of the disease, compared to healthy controls and to evaluate potential...
Supporting primary school children with Juvenile Idiopathic Arthritis
Background: Juvenile Idiopathic Arthritis (JIA) has a deleterious impact on numerous areas of children’s lives including school functioning. This study moves beyond eliciting child reports of school functioning to examine...
Supporting primary school children with Juvenile Idiopathic Arthritis
Background: Juvenile Idiopathic Arthritis (JIA) has a deleterious impact on numerous areas of children’s lives including school functioning. This study moves beyond eliciting child reports of school functioning to examine...
Accommodation-Free Head Mounted Display with Comfortable 3D Perception and an Enlarged Eye-box.
Pawan K Shrestha, Matt J Pryn, Jia Jia, Jhen-Si Chen, Hector Navarro Fructuoso, Atanas Boev, Qing Zhang, Daping Chu
Mar 13, 2020
An accommodation-free displays, also known as Maxwellian displays, keep the displayed image sharp regardless of the viewer's focal distance. However, they typically suffer from a small eye-box and limited effective field of view...
Accommodation-Free Head Mounted Display with Comfortable 3D Perception and an Enlarged Eye-box.
Pawan K Shrestha, Matt J Pryn, Jia Jia, Jhen-Si Chen, Hector Navarro Fructuoso, Atanas Boev, Qing Zhang, Daping Chu
Feb 17, 2020
An accommodation-free displays, also known as Maxwellian displays, keep the displayed image sharp regardless of the viewer's focal distance. However, they typically suffer from a small eye-box and limited effective field of view...
A Study on Pollution in Livestock and Poultry Breeding in Shiyan City
With the investigation and research of agricultural ecology situation, the pollution characteristics of livestock manure were indicated by the statistical analysis of data as well as the effect of livestock and poultry breeding...
Modular forms and SL(2, ℤ)-covariance of type IIB superstring theory
Abstract: The local higher-derivative interactions that enter into the low-energy expansion of the effective action of type IIB superstring theory with constant complex modulus generally violate the U(1) R-symmetry of IIB...
A Study on Pollution in Livestock and Poultry Breeding in Shiyan City
With the investigation and research of agricultural ecology situation, the pollution characteristics of livestock manure were indicated by the statistical analysis of data as well as the effect of livestock and poultry breeding...
Estimation of required sample size for external validation of risk models for binary outcomes
Menelaos Pavlou, Chen Qu, Rumana Z Omar, Shaun R Seaman, Ewout W Steyerberg, Ian R White, Gareth Ambler
Oct 13, 2021
Risk-prediction models for health outcomes are used in practice as part of clinical decision-making, and it is essential that their performance be externally validated. An important aspect in the design of a validation study is...
Water Resources Security Evaluation Based on Matter Element Model in the Yellow River Basin
Water resource is a major limitation of human survival and development. Water security assessment is an important task in the environmental protection and control of water. The solution to assess the grade of water security in...
Water Resources Security Evaluation Based on Matter Element Model in the Yellow River Basin
Water resource is a major limitation of human survival and development. Water security assessment is an important task in the environmental protection and control of water. The solution to assess the grade of water security in...
Thermally stimulated relaxation and behaviors of oxygen vacancies in SrTiO<inf>3</inf> single crystals with (100), (110) and (111) orientations
Abstract
The strontium titanate (SrTiO3 ) single crystals with different orientations of (100), (110) and (111) were investigated using thermally stimulated...
Vortex shaking study of REBCO tape with consideration of anisotropic characteristics
The second generation high temperature superconductor, specifically REBCO, has become a new research focus in the development of a new generation of high-field (>25 T) magnets. One of the main challenges in the application of...
Supramolecular polymer dot ensemble for ratiometric detection of lectins and targeted delivery of imaging agents
Chang Zheng Wang, Jia Li Chen, Ying Tang, Yi Zang, Guo Rong Chen, Tony D. James, Jia Li, Changfeng Wu, Xiao Peng He
Feb 01, 2017
A supramolecular, polymer-dot-based ensemble has been developed for the ratiometric detection of lectins and targeted delivery of glycoprobes. Self-assembly between a blueemitting polymer dot and a red-emitting glycoprobe...
Monocular Depth Matching With Hybrid Sampling and Depth Label Propagation
This paper proposes a monocular depth label propagation model, which describes monocular images into depth label distribution for the target classification matching. 1) Depth label propagation by hybrid sampling and salient...
Published by: IGI Global Scientific Publishing
Two-dimensional electron gas at the PbTi O3/SrTi O3 interface
In the polar catastrophe scenario, polar discontinuity accounts for the driving force of the formation of a two-dimensional electron gas (2DEG) at the interface between polar and nonpolar insulators. In this paper, we substitute...
Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Double-stranded RNA (dsRNA) is a potent proinflammatory signature of viral infection. Long cytosolic dsRNA is recognized by MDA5. The cooperative assembly of MDA5 into helical filaments on dsRNA nucleates the assembly of a...
AGS ATPase Aicardi-Goutières syndrome DExD/H-box RNA helicase RIG-I-like receptor RLR SF2 helicases SMS Singleton-Merten syndrome cryo-EM Cryoelectron Microscopy helical reconstruction innate immune pattern recognition nucleic acid sensing superfamily 2 helicases Adenosine Triphosphate Cryoelectron Microscopy HEK293 Cells Humans Hydrolysis Hydrophobic and Hydrophilic Interactions Interferon-Induced Helicase IFIH1 Interferon-beta Molecular Docking Simulation Mutation Nucleic Acid Conformation Protein Conformation RNA Double-Stranded Signal Transduction Structure-Activity Relationship
Characterization of universal features of partially methylated domains across tissues and species.
Benjamin E Decato, Jianghan Qu, Xiaojing Ji, Elvin Wagenblast, Simon RV Knott, Gregory J Hannon, Andrew D Smith
Dec 14, 2020
BACKGROUND: Partially methylated domains (PMDs) are a hallmark of epigenomes in reproducible and specific biological contexts, including cancer cells, the placenta, and cultured cell lines. Existing methods for deciding whether...
Localized smoothing and concentration for the Navier-Stokes equations in the half space
We establish a local-in-space short-time smoothing effect for the Navier-Stokes equations in the half space. The whole space analogue, due to Jia and Šverák [21], is a central tool in two of the authors' recent work on...
Localized smoothing and concentration for the Navier-Stokes equations in the half space
We establish a local-in-space short-time smoothing effect for the Navier-Stokes equations in the half space. The whole space analogue, due to Jia and Šverák [21], is a central tool in two of the authors' recent work on...
Estimation of required sample size for external validation of risk models for binary outcomes.
Menelaos Pavlou, Chen Qu, Rumana Z Omar, Shaun R Seaman, Ewout W Steyerberg, Ian R White, Gareth Ambler
Mar 18, 2021
Risk-prediction models for health outcomes are used in practice as part of clinical decision-making, and it is essential that their performance be externally validated. An important aspect in the design of a validation study is...
Supramolecular polymer dot ensemble for ratiometric detection of lectins and targeted delivery of imaging agents
Chang Zheng Wang, Jia Li Chen, Ying Tang, Yi Zang, Guo Rong Chen, Tony D. James, Jia Li, Changfeng Wu, Xiao Peng He
Feb 01, 2017
A supramolecular, polymer-dot-based ensemble has been developed for the ratiometric detection of lectins and targeted delivery of glycoprobes. Self-assembly between a blueemitting polymer dot and a red-emitting glycoprobe...
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