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Results: 1125
General tax structures and the Lévy insurance risk model
In the spirit of Albrecher and Hipp (2007), and Albrecher, Renaud, and Zhou (2008) we consider a Levy insurance risk model with tax payments of a more general structure than in the aforementioned papers, which was also...
General tax structures and the Lévy insurance risk model
In the spirit of Albrecher and Hipp (2007), and Albrecher, Renaud, and Zhou (2008) we consider a Levy insurance risk model with tax payments of a more general structure than in the aforementioned papers, which was also...
Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition.
Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F Leadlay, Kui Hong, Zixin Deng, Fuling Zhou, Yuhui Sun
Feb 09, 2023
Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition.
Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F Leadlay, Kui Hong, Zixin Deng, Fuling Zhou, Yuhui Sun
Mar 07, 2023
Modular polyketide synthase (PKS) is an ingenious core machine that catalyzes abundant polyketides in nature. Exploring interactions among modules in PKS is very important for understanding the overall biosynthetic process and...
Published by: Nature Communications
Effects of sedimentation, microgravity, hydrodynamic mixing and air-water interface on α-synuclein amyloid formation.
Jiangtao Zhou, Francesco S Ruggeri, Manuela R Zimmermann, Georg Meisl, Giovanni Longo, Sergey K Sekatskii, Tuomas PJ Knowles, Giovanni Dietler
Jul 28, 2021
The formation of amyloid fibrils is a characterizing feature of a range of protein misfolding diseases, including Parkinson's disease. The propensity of native proteins to form such amyloid fibril, both in vitro and in vivo, is...
Study on Influences of Fringing Reef on Harbor Oscillations Triggered by N-Waves
Influences of topographic variations of the offshore fringing reef on the harbor oscillations excited by incident N-waves with different amplitudes and waveform types are studied for the first time. Both the propagation of...
Fringing-reef topography FUNWAVE-TVD Harbor oscillations N-waves Numerical simulations /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks
Glimm et al. (2010) and Tamhane et al. (2010) studied the problem of testing a primary and a secondary endpoint, subject to a gatekeeping constraint, using a group sequential design (GSD) with K=2 looks. In this article, we...
familywise error rate Gatekeeping Lan-DeMets error spending function approach Multiple comparisons Multiple endpoints O'Brien-Fleming boundary Pocock boundary Primary power Secondary power /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2700/2700 name=General Medicine /dk/atira/pure/subjectarea/asjc/2400/2400 name=General Immunology and Microbiology /dk/atira/pure/subjectarea/asjc/1300/1300 name=General Biochemistry,Genetics and Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1100 name=General Agricultural and Biological Sciences /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Study on Influences of Fringing Reef on Harbor Oscillations Triggered by N-Waves
Influences of topographic variations of the offshore fringing reef on the harbor oscillations excited by incident N-waves with different amplitudes and waveform types are studied for the first time. Both the propagation of...
Fringing-reef topography FUNWAVE-TVD Harbor oscillations N-waves Numerical simulations /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks
Glimm et al. (2010) and Tamhane et al. (2010) studied the problem of testing a primary and a secondary endpoint, subject to a gatekeeping constraint, using a group sequential design (GSD) with K=2 looks. In this article, we...
familywise error rate Gatekeeping Lan-DeMets error spending function approach Multiple comparisons Multiple endpoints O'Brien-Fleming boundary Pocock boundary Primary power Secondary power /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2700/2700 name=General Medicine /dk/atira/pure/subjectarea/asjc/2400/2400 name=General Immunology and Microbiology /dk/atira/pure/subjectarea/asjc/1300/1300 name=General Biochemistry,Genetics and Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1100 name=General Agricultural and Biological Sciences /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Research on supporting mechanism of ancillary service of PV system to grid energy efficiency based on multi-time and space-time operation.
Under the background of high-energy penetration of new energy into the power grid, this paper takes the ancillary service capability of photovoltaic energy integrated into the grid as the starting point and builds a photovoltaic...
Research on supporting mechanism of ancillary service of PV system to grid energy efficiency based on multi-time and space-time operation.
Under the background of high-energy penetration of new energy into the power grid, this paper takes the ancillary service capability of photovoltaic energy integrated into the grid as the starting point and builds a photovoltaic...
Harmonic Analyses of Hydrodynamic Characteristics for Gap Resonance Between Fixed Box and Vertical Wall
Two marine structures arranged side by side with a narrow gap may suffer from violent free-surface resonance, which would cause green water on deck, dramatically raise hydrodynamic loads on structures and seriously threaten...
Gap resonance harmonic analyses OpenFOAM® resonant wave height Wave loads /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitation name=SDG 6 - Clean Water and Sanitation /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
Yang Song, Thomas CT Michaels, Qingming Ma, Zhou Liu, Hao Yuan, Shuichi Takayama, Tuomas PJ Knowles, Ho Cheung Shum
Sep 29, 2018
Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that...
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue.
Maria Grandoch, Ulrich Flögel, Sam Virtue, Julia K Maier, Tomas Jelenik, Christina Kohlmorgen, Kathrin Feldmann, Yanina Ostendorf, Tamara R Castañeda, Zhou Zhou, Yu Yamaguchi, Emmani BM Nascimento, Vivekananda G Sunkari, Christine Goy, Martina Kinzig, Fritz Sörgel, Paul L Bollyky, Patrick Schrauwen, Hadi Al-Hasani, Michael Roden, Susanne Keipert, Antonio Vidal-Puig, Martin Jastroch, Judith Haendeler, Jens W Fischer
Oct 09, 2020
Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix, which...
Harmonic Analyses of Hydrodynamic Characteristics for Gap Resonance Between Fixed Box and Vertical Wall
Two marine structures arranged side by side with a narrow gap may suffer from violent free-surface resonance, which would cause green water on deck, dramatically raise hydrodynamic loads on structures and seriously threaten...
Gap resonance harmonic analyses OpenFOAM® resonant wave height Wave loads /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitation name=SDG 6 - Clean Water and Sanitation /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water
An Empirical Study on the Network Model and the Online Knowledge Production Structure
Mass production has attracted much attention as a new approach to knowledge production. The R software system is a typical product of mass production. For its unique architecture, the R software system accurately recorded the...
Published by: IGI Global Scientific Publishing
Semantic Decision Internal-Attention Graph Convolutional Network for End-to-End Emotion-Cause Pair Extraction
Emotion-cause pair extraction is an emergent natural language processing task; the target is to extract all pairs of emotion clauses and corresponding cause clauses from unannotated emotion text. Previous studies have employed...
Published by: IGI Global Scientific Publishing
Autocalibration of accelerometer data for free-living physical activity assessment using local gravity and temperature
Vincent T van Hees, Zhou Fang, Joss Langford, Felix Assah, Anwar Mohammad, Inacio CM da Silva, Michael I Trenell, Tom White, Nicholas J Wareham, Søren Brage
Aug 22, 2014
Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells
Dan Zhao, Hai Hao Han, Ling Zhu, Fang Zhou Xu, Xing Yu Ma, Jia Li, Tony D. James, Yi Zang, Xiao Peng He, Chengyun Wang
Sep 20, 2021
With this research, we have developed two long-wavelength theranostic probes (DCMT and DCMC) with aggregation-induced emission (AIE)-based properties for image-guided photodynamic therapy (PDT) of hepatoma cells. Introduction...
aggregation-induced emission (AIE) Mitochondria photodynamic therapy (PDT) photosensitizer theranostic probe /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Design a Wireless Covert Channel Based on Dither Analog Chaotic Code
Pengcheng Cao, Weiwei Liu, Guangjie Liu, Jiangtao Zhai, Xiao-Peng Ji, Yuewei Dai, Huiwen Bai
Mar 01, 2021
To conceal the very existence of communication, the noise-based wireless covert channel modulates secret messages into artificial noise, which is added to the normal wireless signal. Although the state-of-the-art work based on...
Published by: IGI Global Scientific Publishing
Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells
Dan Zhao, Hai Hao Han, Ling Zhu, Fang Zhou Xu, Xing Yu Ma, Jia Li, Tony D. James, Yi Zang, Xiao Peng He, Chengyun Wang
Sep 20, 2021
With this research, we have developed two long-wavelength theranostic probes (DCMT and DCMC) with aggregation-induced emission (AIE)-based properties for image-guided photodynamic therapy (PDT) of hepatoma cells. Introduction...
aggregation-induced emission (AIE) Mitochondria photodynamic therapy (PDT) photosensitizer theranostic probe /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells.
Helle F Jørgensen, Anna Terry, Chiara Beretta, C Filipe Pereira, Marion Leleu, Zhou-Feng Chen, Claire Kelly, Matthias Merkenschlager, Amanda G Fisher
May 04, 2018
REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in controlling the expression of transcription factor genes that are...
GC content shapes mRNA storage and decay in human cells
Maïté Courel, Yves Clément, Clémentine Bossevain, Dominika Foretek, Olivia Vidal Cruchez, Zhou Yi, Marianne Bénard, Marie-Noëlle Benassy, Michel Kress, Caroline Vindry, Michèle Ernoult-Lange, Christophe Antoniewski, Antonin Morillon, Patrick Brest, Arnaud Hubstenberger, Hugues Roest Crollius, Nancy Standart, Dominique Weil
Jan 07, 2020
Numerical investigation on effects of fringing reefs on low-frequency oscillations within a harbor
The low-frequency (LF) oscillations inside an elongated rectangular harbor near the offshore fringing reef excited by bi-chromatic short wave groups are simulated using a fully nonlinear Boussinesq model. Based on a LF wave...
GC content shapes mRNA storage and decay in human cells.
Maïté Courel, Yves Clément, Clémentine Bossevain, Dominika Foretek, Olivia Vidal Cruchez, Zhou Yi, Marianne Bénard, Marie-Noëlle Benassy, Michel Kress, Caroline Vindry, Michèle Ernoult-Lange, Christophe Antoniewski, Antonin Morillon, Patrick Brest, Arnaud Hubstenberger, Hugues Roest Crollius, Nancy Standart, Dominique Weil
Mar 09, 2020
mRNA translation and decay appear often intimately linked although the rules of this interplay are poorly understood. In this study, we combined our recent P-body transcriptome with transcriptomes obtained following silencing of...
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