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Results: 575
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Leo Kiss, Jingwei Zeng, Claire F Dickson, Donna L Mallery, Ji-Chun Yang, Stephen H McLaughlin, Andreas Boland, David Neuhaus, Leo C James
Oct 02, 2020
The cytosolic antibody receptor TRIM21 possesses unique ubiquitination activity that drives broad-spectrum anti-pathogen targeting and underpins the protein depletion technology Trim-Away. This activity is dependent on formation...
Amino Acid Motifs Antiviral Restriction Factors Biocatalysis Crystallography X-Ray HEK293 Cells HeLa Cells Humans Lysine Models Molecular Mutation Nuclear Magnetic Resonance Biomolecular Protein Binding Ribonucleoproteins Tripartite Motif Proteins Ubiquitin Ubiquitin-Conjugating Enzymes Ubiquitin-Protein Ligases Ubiquitination
A Multimodal Sentiment Analysis Method Integrating Multi-Layer Attention Interaction and Multi-Feature Enhancement
To address issues related to the insufficient representation of text semantic information and the lack of deep fusion between internal modal information and intermodal information in current multimodal sentiment analysis (MSA)...
Published by: IGI Global Scientific Publishing
Time of day is associated with paradoxical reductions in global signal fluctuation and functional connectivity.
The brain exhibits substantial diurnal variation in physiology and function, but neuroscience studies rarely report or consider the effects of time of day. Here, we examined variation in resting-state functional MRI (fMRI) in...
Linking defects, hierarchical porosity generation and desalination performance in metal-organic frameworks.
Weibin Liang, Lin Li, Jingwei Hou, Nicholas D Shepherd, Thomas D Bennett, Deanna M D'Alessandro, Vicki Chen
Oct 10, 2018
Composite membranes with defective metal-organic frameworks (MOFs) connect the emerging fields of MOF topological modification, MOF-polymer interfacial engineering and composite material functionalization. Although defective...
DGFN Multimodal Emotion Analysis Model Based on Dynamic Graph Fusion Network
In recent years, integrating text and image data for sentiment analysis in social networks has become a key approach. However, techniques for capturing complex cross-modal information and effectively fusing multimodal features...
Published by: IGI Global Scientific Publishing
Quantifying wind-induced impacts on particulate Cu footprint in the Yangtze Estuary.
Zeng Yichuan, Wang Hua, Liang Dongfang, Yuan Weihao, Li Bao, Zhuang Wei, John Paul Kaisam, Shen Wenbo
Oct 06, 2020
Under two wind conditions, a polar coordinated segmented quantification method (PCSQM) taking the easternmost point of Chongming Island (121°59'20″E, 31°29'38″N) as the origin of the coordinate was proposed to quantify...
Metal-organic framework gels and monoliths.
The synthesis of metal-organic frameworks (MOFs) has, to date, largely been in the form of crystalline powders. However, interest in different physical morphologies of this class of materials is growing. In this perspective, we...
Pulmonary Thrombosis Promotes Tumorigenesis via Myeloid Hypoxia-Inducible Factors.
Cancer patients have a greater risk of thrombosis than individuals without cancer. Conversely, thrombosis is a diagnostic predictor of cancer, but the mechanisms by which thrombosis promotes tumor propagation are incompletely...
A Lithium-Ion Pump Based on Piezoelectric Effect for Improved Rechargeability of Lithium Metal Anode.
Jingwei Xiang, Zexiao Cheng, Ying Zhao, Bao Zhang, Lixia Yuan, Yue Shen, Zezhou Guo, Yi Zhang, Jianjun Jiang, Yunhui Huang
Jan 03, 2020
Lithium metal is widely studied as the "crown jewel" of potential anode materials due to its high specific capacity and low redox potential. Unfortunately, the Li dendrite growth limits its commercialization. Previous research...
Phase boundary engineering of metal-organic-framework-derived carbonaceous nickel selenides for sodium-ion batteries
Shiyao Lu, Hu Wu, Jingwei Hou, Limin Liu, Jiao Li, Chris J. Harris, Cheng-Yen Lao, Yuzheng Guo, Kai Xi, Shujiang Ding, Guoxin Gao, Anthony K. Cheetham, R. Vasant Kumar
Jul 20, 2020
Abstract: Sodium-ion batteries (SIBs) are promising power sources due to the low cost and abundance of battery-grade sodium resources, while practical SIBs suffer from intrinsically sluggish diffusion kinetics and severe volume...
Bacteriophage host range evolution through engineered enrichment bias, exploiting heterologous surface receptor expression.
Research on the initial phage-host interaction has been conducted on a limited repertoire of phages and their cognate receptors, such as phage λ and the Escherichia coli LamB (EcLamB) protein. Apart from phage λ, little is known...
Predicting the behavioural tendency of loss aversion.
Jianmin Zeng, Yujiao Wang, Jing Zeng, Zhipeng Cao, Hong Chen, Yijun Liu, Qinglin Zhang, Li Su
Apr 18, 2019
Loss aversion manifests itself in rejecting a gamble of gaining or losing the same amount of money with equal chance. Although loss aversion is a well-known and intensively studied phenomenon, whether individual differences in...
Pavement Crack Detection and Identification Based on Improved YOLOv8
Aiming at the problem of poor real-time performance and low precision of traditional pavement crack detection, an improved YOLOv8 algorithm is proposed to realize the automatic pavement crack detection and identification....
Published by: IGI Global Scientific Publishing
Balancing Exploration and Exploitation With Decomposition-Based Dynamic Multi-Objective Evolutionary Algorithm
Balancing exploration and exploitation is a crucial issue in evolutionary global optimization. This paper proposes a decomposition-based dynamic multi-objective evolutionary algorithm for addressing global optimization problems....
Published by: IGI Global Scientific Publishing
Elliptical Slot Microstrip Patch Antenna Design Based on a Dynamic Constrained Multiobjective Optimization Evolutionary Algorithm
Most evolutionary optimization algorithms have already been used for antenna design and shown promising results on improving the performance of the antenna. However, for many real-world antenna optimization problems, they are...
Published by: IGI Global Scientific Publishing
Resistive Superconducting Fault Current Limiter AC Loss Measurements and Analysis
Resistive superconducting fault current limiters (SFCLs) offer the advantages of low weight and compact structure. Multistrand magnesium diboride (MgB2) wire can be used in the SFCL coil design to increase the...
A POI Recommendation Model for Intelligent Systems Using AT-LSTM in Location-Based Social Network Big Data
In location-based social networks (LBSN), users can check-in at points of interest (POI) to record their trips. POI recommendation is an important service provided by LBSN; it can help users quickly find POI of interest, and...
Published by: IGI Global Scientific Publishing
Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Thomas Sommermann, Tomoharu Yasuda, Jonathan Ronen, Tristan Wirtz, Timm Weber, Ulrike Sack, Rebecca Caeser, Jingwei Zhang, Xun Li, Van Trung Chu, Anna Jauch, Kristian Unger, Daniel J Hodson, Altuna Akalin, Klaus Rajewsky
Jun 15, 2020
Epstein-Barr virus (EBV) is a B cell transforming virus that causes B cell malignancies under conditions of immune suppression. EBV orchestrates B cell transformation through its latent membrane proteins (LMPs) and Epstein-Barr...
B cell lymphomagenesis EBNA Epstein-Barr virus LMP1 plasma cell differentiation Animals Cell Differentiation Cell Line Tumor Cell Transformation Viral DNA-Binding Proteins Disease Models Animal Epstein-Barr Virus Infections Epstein-Barr Virus Nuclear Antigens FIBROBLASTS Herpesvirus 4 Human Humans Lymphoma B-Cell Mice Mice Knockout Plasma Cells Primary Cell Culture Trans-Activators Viral Matrix Proteins Viral Proteins
Mouse Papillomavirus L1 and L2 Are Dispensable for Viral Infection and Persistence at Both Cutaneous and Mucosal Tissues
Sarah Brendle, Jingwei J. Li, Nancy M. Cladel, Debra A. Shearer, Lynn R. Budgeon, Karla K. Balogh, Hannah Atkins, Marina Costa-Fujishima, Paul Lopez, Neil D. Christensen, John Doorbar, Thomas T. Murooka, Jiafen Hu
Sep 15, 2021
Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth...
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