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Results: 7659
f-scLVM
Florian Buettner, Naruemon Pratanwanich, Davis J McCarthy, John C Marioni, Oliver Stegle
Mar 26, 2018
Single-cell RNA-sequencing (scRNA-seq) allows studying heterogeneity in gene expression in large cell populations. Such heterogeneity can arise due to technical or biological factors, making decomposing sources of variation...
Gene set annotations Single-cell RNA-seq Sparse factor analysis Animals Computer Simulation Databases as Topic Factor Analysis Statistical Gene Expression Regulation Mice Models Theoretical Mouse embryonic stem cells Neurons Reproducibility of Results Sequence Analysis RNA Single-Cell Analysis Software
Synthesis and characterization of fluorinated β-ketoiminate zinc precursors and their utility in the AP-MOCVD growth of ZnO
Andrew L. Johnson, Samuel D. Cosham, Gabriele Kociok-Kohn, Jeff A. Hamilton, Michael S. Hill, Kieran C. Molloy, Remi Castaing
Sep 01, 2015
A novel family of zinc bis beta-ketoiminate complexes 2b-2h have been synthesized by reaction of the isolated free ligands (1a-h) with dimethylzinc. The isolated zinc complexes were characterized by elemental analysis, NMR...
Synthesis and characterization of fluorinated β-ketoiminate zinc precursors and their utility in the AP-MOCVD growth of ZnO
Andrew L. Johnson, Samuel D. Cosham, Gabriele Kociok-Kohn, Jeff A. Hamilton, Michael S. Hill, Kieran C. Molloy, Remi Castaing
Sep 01, 2015
A novel family of zinc bis beta-ketoiminate complexes 2b-2h have been synthesized by reaction of the isolated free ligands (1a-h) with dimethylzinc. The isolated zinc complexes were characterized by elemental analysis, NMR...
Selective Inhibition of Bruton's Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors.
Bárbara B Sousa, Cátia Rebelo de Almeida, Ana F Barahona, Raquel Lopes, Ana Martins-Logrado, Marco Cavaco, Vera Neves, Luís AR Carvalho, Carlos Labão-Almeida, Ana R Coelho, Marta Leal Bento, Ricardo MRM Lopes, Bruno L Oliveira, Miguel ARB Castanho, Peter Neumeister, Alexander Deutsch, Gregory I Vladimer, Nikolaus Krall, Cristina João, Francisco Corzana, João D Seixas, Rita Fior, Gonçalo JL Bernardes
Nov 15, 2022
Bruton's tyrosine kinase (BTK) is a member of the TEC-family kinases and crucial for the proliferation and differentiation of B-cells. We evaluated the therapeutic potential of a covalent inhibitor (JS25) with nanomolar potency...
Knowledge Sharing in Catholic Organizations
This study examines knowledge sharing in Catholic organizations. The authors adopt Schein's organizational culture theory that facilitates, or inhibits, knowledge sharing in organizations. Thus, they address the phenomenon at...
Published by: IGI Global Scientific Publishing
Homer F. Swift, 1920
The Rockefeller University
Jan 01, 0001
Homer F. Swift, M.D. Trench Fever
Lecture delivered January 10th, 1920
Published by: J.B. Lippincott Company
Spin in the neurosurgical trauma literature
João Vitor Miranda Porto Oliveira, André Luiz Freitas Oliveira Júnior, Angelos G Kolias, Wellingson S Paiva, Davi Jorge Fontoura Solla
Jan 10, 2022
INTRODUCTION: Spin is defined as an inaccurate interpretation of results, intentionally or not, leading to equivocal conclusions and misdirecting readers to look at the data in an overly optimistic way. Previous studies have...
Systematics of the α′ expansion in F-theory
Abstract: Extracting reliable low-energy information from string compactifications notoriously requires a detailed understanding of the UV sensitivity of the corresponding effective field theories. Despite past efforts in...
C-F Bond Activation of P(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub> By Ruthenium Dihydride Complexes
The major product of the reaction between Ru(IMe4)2(PPh3)2H2 (1; IMe4 = 1,3,4,5-tetramethylimidazol-2-ylidene) and P(C6F5)3 (PCF)...
C-F Bond Activation of P(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub> By Ruthenium Dihydride Complexes
The major product of the reaction between Ru(IMe4)2(PPh3)2H2 (1; IMe4 = 1,3,4,5-tetramethylimidazol-2-ylidene) and P(C6F5)3 (PCF)...
The cytotoxic effect of TiF4 and NaF on fibroblasts is influenced by the experimental model, fluoride concentration and exposure time.
Priscila Maria Aranda Salomão, Flávia Amadeu de Oliveira, Paula Danielle Rodrigues, Luana Polioni Al-Ahj, Kellen Cristina da Silva Gasque, Pia Jeggle, Marilia Afonso Rabelo Buzalaf, Rodrigo Cardoso de Oliveira, John Michael Edwardson, Ana Carolina Magalhães
Oct 22, 2018
OBJECTIVE: Titanium tetrafluoride (TiF4) has shown promising effect in preventing tooth lesions. Therefore, we compared the cytotoxicity of TiF4 with sodium fluoride (NaF) (already applied in Dentistry) considering different...
Experimental and computational studies of the copper borate complexes [(NHC)Cu(HBEt<sub>3</sub>)] and [(NHC)Cu(HB(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub>)]
Lee R. Collins, Nasir A. Rajabi, Stuart A. Macgregor, Mary F. Mahon, Michael K. Whittlesey
Dec 05, 2016
The synthesis of the Cu-borate complexes [(6Mes)Cu(HBR3)] featuring the unusual [HBEt3]− (5) and [HB(C6F5)3]− (6) ligands is described. Experimental...
Systematics of the α′ expansion in F-theory
Extracting reliable low-energy information from string compactifications
notoriously requires a detailed understanding of the UV sensitivity of the
corresponding effective field theories. Despite past efforts in...
Cross-Module Enoylreduction in the Azalomycin F Polyketide Synthase.
Guifa Zhai, Wenyan Wang, Wei Xu, Guo Sun, Chaoqun Hu, Xiangming Wu, Zisong Cong, Liang Deng, Yanrong Shi, Peter F Leadlay, Heng Song, Kui Hong, Zixin Deng, Yuhui Sun
Oct 19, 2020
The colinearity of canonical modular polyketide synthases, which creates a direct link between multienzyme structure and the chemical structure of the biosynthetic end-product, has become a cornerstone of knowledge-based genome...
Experimental and computational studies of the copper borate complexes [(NHC)Cu(HBEt<sub>3</sub>)] and [(NHC)Cu(HB(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub>)]
Lee R. Collins, Nasir A. Rajabi, Stuart A. Macgregor, Mary F. Mahon, Michael K. Whittlesey
Dec 05, 2016
The synthesis of the Cu-borate complexes [(6Mes)Cu(HBR3)] featuring the unusual [HBEt3]− (5) and [HB(C6F5)3]− (6) ligands is described. Experimental...
The management of COVID-19 cases through telemedicine in Brazil.
Alfredo Montelongo, João Luiz Becker, Rudi Roman, Elise Botteselle de Oliveira, Roberto Nunes Umpierre, Marcelo Rodrigues Gonçalves, Rodolfo Silva, Katarzyna Doniec, Ali K Yetisen
Aug 14, 2021
In Dec 2020 Brazil became one of the worldwide epicenters of the COVID-19 pandemic with more than 7.2M reported cases. Brazil has a large territory with unequal distribution of healthcare resources including physicians. Resource...
Clinical significance of prostate (18)F-labelled fluorodeoxyglucose uptake on positron emission tomography/computed tomography
AIM: To determine the significance and need for investigation of incidental prostatic uptake in men undergoing (18)F-labelled fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) for other...
Developing local RG
Abstract: In this paper we study various forms of RG and apply these to the BFSS model of N coincident D0-branes. Firstly, as a warm-up, we perform standard Wilsonian RG, investigating the conditions under which supersymmetry is...
F-Actin nucleated on chromosomes coordinates their capture by microtubules in oocyte meiosis.
Capture of each and every chromosome by spindle microtubules is essential to prevent chromosome loss and aneuploidy. In somatic cells, astral microtubules search and capture chromosomes forming lateral attachments to...
Principles for Engineering Social Interaction in Asynchronous Mobile Games
Since their first appearance, mobile devices have had exponential technological growth and have gained other functionalities besides standard calls and messaging services. With the advent of smartphones, the mobile gaming market...
Published by: IGI Global Scientific Publishing
Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N-Propargyl Handles for Drug-Activation.
Bruno L Oliveira, Benjamin J Stenton, VB Unnikrishnan, Cátia Rebelo de Almeida, João Conde, Magda Negrão, Felipe SS Schneider, Carlos Cordeiro, Miguel Godinho Ferreira, Giovanni F Caramori, Josiel B Domingos, Rita Fior, Gonçalo JL Bernardes
Jun 01, 2020
Phylogenetic Analysis and Karyotype Evolution in Two Species of Core Gruiformes
Ivanete de Oliveira Furo, Rafael Kretschmer, Patrícia CM O'Brien, Jorge C Pereira, Malcolm A Ferguson-Smith, Edivaldo Herculano Corrêa de Oliveira
Jun 01, 2020
Gruiformes is a group with phylogenetic issues. Recent studies based on mitochondrial and genomic DNA have proposed the existence of a core Gruiformes, consisting of five families: Heliornithidae, Aramidae, Gruidae, Psophiidae...
Developing local RG
Abstract: In this paper we study various forms of RG and apply these to the BFSS model of N coincident D0-branes. Firstly, as a warm-up, we perform standard Wilsonian RG, investigating the conditions under which supersymmetry is...
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