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Results: 276
Striated Muscle in Radical Prostatectomy Specimens
Daniel W Good, Andrew Wood, Laurence Stewart, Jens-Uwe Stolzenburg, Roman Ganzer, Jochen Neuhaus, Grant D Stewart, S Alan McNeill
Dec 20, 2016
INTRODUCTION: The study aimed to determine if the presence and amount of striated muscle on the apical sections of the cruciate sections of laparoscopic radical prostatectomy (LRP) specimens predict early and long-term urinary...
G-quadruplexes are transcription factor binding hubs in human chromatin.
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Mar 26, 2021
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells.
Xiaoyun Zhang, Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Shankar Balasubramanian
Aug 02, 2021
DNA-protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential to understand the underlying regulatory mechanisms on a molecular level. Here we...
Published by: Nature chemistry
Evolutionary programming as a platform for in silico metabolic engineering.
BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the...
Algorithms Benzaldehydes Computational Biology Computer Simulation Escherichia coli evolution Molecular Gene Expression Regulation Genetic Engineering Genome Fungal Glycerol Models Biological Models Genetic Phenotype Protein Engineering Protein Interaction Mapping Saccharomyces cerevisiae Software Succinic Acid
The regulation and functions of DNA and RNA G-quadruplexes.
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian
Mar 13, 2020
Optical band gap of cross-linked, curved, and radical polyaromatic hydrocarbons.
Angiras Menon, Jochen AH Dreyer, Jacob W Martin, Jethro Akroyd, John Robertson, Markus Kraft
Sep 09, 2019
In this work, the optical band gaps of polycyclic aromatic hydrocarbons (PAHs) crosslinked via an aliphatic bond, curved via pentagon integration and with radical character were computed using density functional theory. A...
Religious people only live longer in religious cultural contexts
Religious people live longer than non-religious people according to a staple of social science research. Yet, are those longevity benefits an inherent feature of religiosity? To find out, we coded gravestone inscriptions and...
Cross-cultural variations in big five relationships with religiosity
Jochen E Gebauer, Wiebke Bleidorn, Samuel D Gosling, Peter J Rentfrow, Michael E Lamb, Jeff Potter
Mar 16, 2015
Brain tissue stiffness is a sensitive marker for acidosis.
Kathrin Holtzmann, Hélène OB Gautier, Andreas F Christ, Jochen Guck, Ragnhildur Thóra Káradóttir, Kristian Franze
Aug 15, 2016
G-quadruplexes are transcription factor binding hubs in human chromatin
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Apr 23, 2021
Abstract: Background: The binding of transcription factors (TF) to genomic targets is critical in the regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely implicated in TF recruitment, but many...
Phase Behavior and Substitution Limit of Mixed Cesium-Formamidinium Lead TriIodide Perovskites
Bethan Charles, Mark T. Weller, Sebastian Rieger, Lauren Hatcher, Paul F. Henry, Jochen Feldmann, Daniel Wolverson, Chick Wilson
Mar 24, 2020
The mixed cation lead iodide perovskite photovoltaics show improved stability following site substitution of cesium ions (Cs +) onto the formamidinium cation sites (FA +) of (CH(NH 2)...
Improved methodology for performing the inverse Abel transform of flame images for color ratio pyrometry.
Jochen AH Dreyer, Radomir I Slavchov, Eric J Rees, Jethro Akroyd, Maurin Salamanca, Sebastian Mosbach, Markus Kraft
Apr 05, 2019
A new method is presented for performing the Abel inversion by fitting the line-of-sight projection of a predefined intensity distribution (FLiPPID) to the recorded 2D projections. The aim is to develop a methodology that is...
The sharpness of gamma-ray burst prompt emission spectra
Hoi Fung Yu, Hendrik J. van Eerten, Jochen Greiner, Re'em Sari, P. Narayana Bhat, Andreas von Kienlin, William S. Paciesas, Robert D. Preece
Nov 30, 2015
Context. We study the sharpness of the time-resolved prompt emission spectra of gamma-ray bursts (GRBs) observed by the Gamma-ray Burst Monitor (GBM) on board the Fermi Gamma-ray Space Telescope.
Aims. We aim to obtain...
Aims. We aim to obtain...
The host galaxy of the short GRB 050709
Ana Nicuesa Guelbenzu, Sylvio Klose, Patricia Schady, Jochen Greiner, D.H. Hartmann, Leslie Hunt, Benjamin Magnelli, Nicola Masetti, Michal Michalowski, Eliana Palazzi, Andrea Rossi, Mark Wieringa, Bringfried Stecklum
Jun 30, 2021
The host of the short gamma-ray burst (GRB) 050709 is a morphologically disturbed low-luminous galaxy. At a redshift of z = 0.16, it belongs to one of the cosmologically nearest short-GRB hosts identified to date. Consequently...
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Leo Kiss, Jingwei Zeng, Claire F Dickson, Donna L Mallery, Ji-Chun Yang, Stephen H McLaughlin, Andreas Boland, David Neuhaus, Leo C James
Oct 02, 2020
The cytosolic antibody receptor TRIM21 possesses unique ubiquitination activity that drives broad-spectrum anti-pathogen targeting and underpins the protein depletion technology Trim-Away. This activity is dependent on formation...
Amino Acid Motifs Antiviral Restriction Factors Biocatalysis Crystallography X-Ray HEK293 Cells HeLa Cells Humans Lysine Models Molecular Mutation Nuclear Magnetic Resonance Biomolecular Protein Binding Ribonucleoproteins Tripartite Motif Proteins Ubiquitin Ubiquitin-Conjugating Enzymes Ubiquitin-Protein Ligases Ubiquitination
Phase Behavior and Substitution Limit of Mixed Cesium-Formamidinium Lead TriIodide Perovskites
Bethan Charles, Mark T. Weller, Sebastian Rieger, Lauren Hatcher, Paul F. Henry, Jochen Feldmann, Daniel Wolverson, Chick Wilson
Mar 24, 2020
The mixed cation lead iodide perovskite photovoltaics show improved stability following site substitution of cesium ions (Cs +) onto the formamidinium cation sites (FA +) of (CH(NH 2)...
Cultural norm fulfillment, interpersonal belonging, or getting ahead? A large-scale cross-cultural test of three perspectives on the function of self-esteem.
Jochen E Gebauer, Constantine Sedikides, Jenny Wagner, Wiebke Bleidorn, Peter J Rentfrow, Jeff Potter, Samuel D Gosling
Jun 16, 2015
Synergistic photoluminescence enhancement in conjugated polymer-di-ureasil organic-inorganic composites.
Niamh Willis-Fox, Ana-Teresa Marques, Jochen Arlt, Ullrich Scherf, Luís D Carlos, Hugh D Burrows, Rachel C Evans
Jul 03, 2018
Poly(fluorene) conjugated polyelectrolyte (CPE)-di-ureasil organic-inorganic composites have been prepared using a versatile sol-gel processing method, which enables selective localisation of the CPE within the di-ureasil...
Polymorphism of nanocrystalline TiO2 prepared in a stagnation flame
Manoel Y Manuputty, Jochen AH Dreyer, Yuan Sheng, Eric J Bringley, Maria L Botero, Jethro Akroyd, Markus Kraft
Jan 29, 2019
A metastable "high-pressure" phase known as α-PbO2-type TiO2 or TiO2-II is prepared via a single-step synthesis using a laminar premixed stagnation flame. Three other TiO2 polymorphs, namely anatase, rutile and TiO2-B phases...
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