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Results: 301
Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging.
Maiara S Severo, Jonathan JM Landry, Randall L Lindquist, Christian Goosmann, Volker Brinkmann, Paul Collier, Anja E Hauser, Vladimir Benes, Johan Henriksson, Sarah A Teichmann, Elena A Levashina
May 14, 2019
Mosquito blood cells are immune cells that help control infection by vector-borne pathogens. Despite their importance, little is known about mosquito blood cell biology beyond morphological and functional criteria used for their...
Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation.
Jhuma Pramanik, Xi Chen, Gozde Kar, Johan Henriksson, Tomás Gomes, Jong-Eun Park, Kedar Natarajan, Kerstin B Meyer, Zhichao Miao, Andrew NJ McKenzie, Bidesh Mahata, Sarah A Teichmann
May 14, 2019
BACKGROUND: The IRE1a-XBP1 pathway is a conserved adaptive mediator of the unfolded protein response. The pathway is indispensable for the development of secretory cells by facilitating protein folding and enhancing secretory...
Genome-wide XBP1 chromatin occupancy IRE1a IRE1a-XBP1 pathway RNA-seq T helper cell activation Th2 lymphocyte proliferation Th2 transcriptome xbp1 XBP1 ChIP-seq Animals Base Sequence Cell Cycle Cell Differentiation Cell Proliferation Cytokines Endoribonucleases Female Gene Expression Regulation Genome-Wide Association Study Lymphocyte Activation Mice Inbred C57BL Mice Transgenic Protein Serine-Threonine Kinases Signal Transduction Stress Physiological Th2 Cells Up-Regulation X-Box Binding Protein 1
U.S. Disc Golf Championship Returns Oct. 5-8 to Winthrop's Gold Course
Winthrop University
Jan 01, 0001
Top players to watch during the week on the course around the Winthrop Coliseum are: defending champion Paul McBeth, Ricky Wysocki, Ken Climo, Barry Schultz and Karl Johan Nybo. More than 90 participants are expected to compete.
Published by: Winthrop University
Mapping Rora expression in resting and activated CD4+ T cells
Liora Haim-Vilmovsky, Johan Henriksson, Jennifer A. Walker, Zhichao Miao, Eviatar Natan, Gozde Kar, Simon Clare, Jillian L. Barlow, Evelina Charidemou, Lira Mamanova, Xi Chen, Valentina Proserpio, Jhuma Pramanik, Steven Woodhouse, Anna V. Protasio, Mirjana Efremova, Julian L. Griffin, Matt Berriman, Gordon Dougan, Jasmin Fisher, John C. Marioni, Andrew N. J. McKenzie, Sarah A. Teichmann
May 20, 2021
Gene expression variability across cells and species shapes innate immunity.
Tzachi Hagai, Xi Chen, Ricardo J Miragaia, Raghd Rostom, Tomás Gomes, Natalia Kunowska, Johan Henriksson, Jong-Eun Park, Valentina Proserpio, Giacomo Donati, Lara Bossini-Castillo, Felipe A Vieira Braga, Guy Naamati, James Fletcher, Emily Stephenson, Peter Vegh, Gosia Trynka, Ivanela Kondova, Mike Dennis, Muzlifah Haniffa, Armita Nourmohammad, Michael Lässig, Sarah A Teichmann
May 14, 2019
As the first line of defence against pathogens, cells mount an innate immune response, which varies widely from cell to cell. The response must be potent but carefully controlled to avoid self-damage. How these constraints have...
Mapping Rora expression in resting and activated CD4+ T cells.
Liora Haim-Vilmovsky, Johan Henriksson, Jennifer A Walker, Zhichao Miao, Eviatar Natan, Gozde Kar, Simon Clare, Jillian L Barlow, Evelina Charidemou, Lira Mamanova, Xi Chen, Valentina Proserpio, Jhuma Pramanik, Steven Woodhouse, Anna V Protasio, Mirjana Efremova, Julian L Griffin, Matt Berriman, Gordon Dougan, Jasmin Fisher, John C Marioni, Andrew N J McKenzie, Sarah A Teichmann
Jun 19, 2021
The transcription factor Rora has been shown to be important for the development of ILC2 and the regulation of ILC3, macrophages and Treg cells. Here we investigate the role of Rora across CD4+ T cells in general, but with an...
Published by: PLOS ONE
A lifting method for analyzing distributed synchronization on the unit sphere
This paper introduces a new lifting method for analyzing convergence of continuous-time distributed synchronization/consensus systems on the unit sphere. Points on the d-dimensional unit sphere are lifted to the (d +...
Perception and Processing of Faces in the Human Brain Is Tuned to Typical Feature Locations.
Benjamin de Haas, D Samuel Schwarzkopf, Ivan Alvarez, Rebecca P Lawson, Linda Henriksson, Nikolaus Kriegeskorte, Geraint Rees
Oct 03, 2018
UNLABELLED: Faces are salient social stimuli whose features attract a stereotypical pattern of fixations. The implications of this gaze behavior for perception and brain activity are largely unknown. Here, we characterize and...
decoding fMRI Face perception gaze behavior occipital face area retinotopy Adult Attention Face Female Fixation Ocular Humans Image Processing Computer-Assisted Magnetic Resonance Imaging Male Middle Aged Occipital Lobe Oxygen pattern recognition Visual Photic Stimulation RECOGNITION psychology Young Adult
Mapping Rora expression in resting and activated CD4+ T cells.
Liora Haim-Vilmovsky, Johan Henriksson, Jennifer A Walker, Zhichao Miao, Eviatar Natan, Gozde Kar, Simon Clare, Jillian L Barlow, Evelina Charidemou, Lira Mamanova, Xi Chen, Valentina Proserpio, Jhuma Pramanik, Steven Woodhouse, Anna V Protasio, Mirjana Efremova, Julian L Griffin, Matt Berriman, Gordon Dougan, Jasmin Fisher, John C Marioni, Andrew NJ McKenzie, Sarah A Teichmann
Jul 20, 2021
The transcription factor Rora has been shown to be important for the development of ILC2 and the regulation of ILC3, macrophages and Treg cells. Here we investigate the role of Rora across CD4+ T cells in general, but with an...
Animals Antigens Helminth CD4-Positive T-Lymphocytes Cells Cultured Cytokines Disease Models Animal Female Gene Expression Regulation Lymphocyte Activation MACROPHAGES Mice Mice Inbred C57BL Mice Knockout Mice Transgenic Nippostrongylus Nuclear Receptor Subfamily 1 Group F Member 1 Pneumonia Strongylida Infections Th2 Cells
Towards powerful educational knowledge?
This paper introduces a special issue which aims to address the challenges facing the ‘deliberative’ educational knowledge traditions of educational foundations, curriculum theory and Didaktik as a consequence of the rising tide...
Seeing and Treating the Out-group Like Family
Transference effects occur when our impressions are guided by our mental representations of significant others. For instance, if a target resembles an individual’s significant other, then that person’s feelings toward their...
Entrepreneurship and psychological disorders
Amidst predominant focus on positive traits for entrepreneurship, this paper explores how disorders such as ADHD influence the decision to engage in entrepreneurial action and the success of entrepreneurial action. Based on a...
Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, Christel Reuterswärd, Anna Karlsson, Shamik Mitra, Emma Niméus, Karolina Holm, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Christer Larsson, Martin Malmberg, Lisa Rydén, Anna Ehinger, Niklas Loman, Anders Kvist, Hans Ehrencrona, Serena Nik-Zainal, Åke Borg, Johan Staaf
Jul 28, 2021
Development of a tilt control method for a narrow-track three-wheeled vehicle
The space and weight savings provided by narrow tilting vehicles could make them a solution to the pollution and congestion problems seen in urban environments. The success of this new type of vehicle relies heavily on the...
Lateral dynamics simulation of a three-wheeled tilting vehicle
A novel tilting three-wheeled vehicle was developed at the University of Bath as part of a project funded by the European Union. The space and weight savings provided by this type of vehicle could be a solution to the pollution...
Lateral dynamics simulation of a three-wheeled tilting vehicle
A novel tilting three-wheeled vehicle was developed at the University of Bath as part of a project funded by the European Union. The space and weight savings provided by this type of vehicle could be a solution to the pollution...
A computational method for sharp interface advection.
We devise a numerical method for passive advection of a surface, such as the interface between two incompressible fluids, across a computational mesh. The method is called isoAdvector, and is developed for general meshes...
Non-linear control of a hydraulic piezo-valve using a generalized Prandtl-Ishlinskii hysteresis model
Frederik Stefanski, Bartosz Minorowicz, Johan Persson, Andrew Plummer, Christopher Bowen
Jan 01, 2017
The potential to actuate proportional flow control valves using piezoelectric ceramics or other smart materials has been investigated for a number of years. Although performance advantages compared to electromagnetic actuation...
Towards powerful educational knowledge?
This paper introduces a special issue which aims to address the challenges facing the ‘deliberative’ educational knowledge traditions of educational foundations, curriculum theory and Didaktik as a consequence of the rising tide...
Single-cell reconstruction of the early maternal-fetal interface in humans.
Roser Vento-Tormo, Mirjana Efremova, Rachel A Botting, Margherita Y Turco, Miquel Vento-Tormo, Kerstin B Meyer, Jong-Eun Park, Emily Stephenson, Krzysztof Polański, Angela Goncalves, Lucy Gardner, Staffan Holmqvist, Johan Henriksson, Angela Zou, Andrew M Sharkey, Ben Millar, Barbara Innes, Laura Wood, Anna Wilbrey-Clark, Rebecca P Payne, Martin A Ivarsson, Steve Lisgo, Andrew Filby, David H Rowitch, Judith N Bulmer, Gavin J Wright, Michael JT Stubbington, Muzlifah Haniffa, Ashley Moffett, Sarah A Teichmann
Dec 10, 2018
The impact of financial slack on explorative and exploitative knowledge sourcing from universities
Some organizations use universities to explore new areas, whereas others turn to universities to exploit knowledge for immediate and practical gain. Drawing on the behavioral theory of the firm and the literature on...
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