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Results: 67
Selective inhibition of protein secretion by abrogating receptor-coat interactions during ER export.
Natalia Gomez-Navarro, Julija Maldutyte, Kristina Poljak, Sew-Yeu Peak-Chew, Jonathon Orme, Brittany J Bisnett, Caitlin H Lamb, Michael Boyce, Davide Gianni, Elizabeth A Miller
Aug 02, 2022
Protein secretion is an essential process that drives cell growth, movement, and communication. Protein traffic within the secretory pathway occurs via transport intermediates that bud from one compartment and fuse with a...
We must look further upstream to enable planetary health-literate urban development
The gap between academic research and real-world practice in urban planning and development is a major barrier to planetary health.1 By exploring uncertainty and complexity further upstream, we might be able to narrow that gap...
We must look further upstream to enable planetary health-literate urban development
The gap between academic research and real-world practice in urban planning and development is a major barrier to planetary health.1 By exploring uncertainty and complexity further upstream, we might be able to narrow that gap...
The Future of Cardiovascular Computed Tomography
Edward D Nicol, Bjarne L Norgaard, Philipp Blanke, Amir Ahmadi, Jonathon Weir-McCall, Pal Maurovich Horvat, Kelly Han, Jeroen J Bax, Jonathon Leipsic
Jan 10, 2020
Cardiovascular computed tomography (CCT) has undergone rapid maturation over the last decade and is now of proven clinical utility in the diagnosis and management of coronary artery disease, in guiding structural heart disease...
FFR(CT) TMVR Atherosclerosis cardiac CT Machine Learning Radiomics Computed Tomography Angiography Coronary Angiography Diffusion of Innovation Forecasting Heart Diseases Humans Models Cardiovascular Patient-Specific Modeling Predictive Value of Tests printing Three-Dimensional Prognosis Tomography Scanners X-Ray Computed
Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis.
Bernhard Strauss, Andrew Harrison, Paula Almeida Coelho, Keiko Yata, Magdalena Zernicka-Goetz, Jonathon Pines
May 02, 2018
There is remarkable redundancy between the Cyclin-Cdk complexes that comprise the cell cycle machinery. None of the mammalian A-, D-, or E-type cyclins are required in development until implantation, and only Cdk1 is essential...
Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein-RNA toxin-antitoxin system.
Feng Rao, Francesca L Short, Jarrod E Voss, Tim R Blower, Anastasia L Orme, Tom E Whittaker, Ben F Luisi, George PC Salmond
Aug 19, 2015
Quarantine encounters with digital animals
Quarantine conditions led to the proliferation of digital encounters with nonhuman animals. Here, we explore three prominent forms: creaturely cameos, avatar acquaintances and background birding. These virtual encounters...
Mitral Valve Imaging with CT
Jonathan R Weir-McCall, Philipp Blanke, Christopher Naoum, Victoria Delgado, Jeroen J Bax, Jonathon Leipsic
Dec 20, 2018
The role of noninvasive imaging to help guide transcatheter aortic valvular interventions is well established and has grown with the advances in the procedure. With the rapid development of new transcatheter mitral valve...
Introduction to the urban ecologies open collection
Catherine Oliver, Shruti Ragavan, Jonathon Turnbull, Anmol Chowdhury, Diane Borden, Thomas Fry, Sneha Gutgutia, Shubhangi Srivastava
Sep 28, 2021
Abstract: This Open Collection proposes innovative research directions for both urban and beyond/more‐than‐/non‐human geographies with animals. We are seeking papers for this Open Collection across three themes: (1) methods; (2)...
OPEN COLLECTION OPEN COLLECTIONS animal geography more‐than‐human methods urban animals urban justice Urban planning
Published by: Geo: Geography and Environment
Kinetics versus Charge SeparationSeparation
Oxygen-deficient iron oxide thin films, which have recently been shown to be highly active for photoelectrochemical water oxidation, were surface-functionalized with a monolayer of a molecular iridium water oxidation cocatalyst....
Inherited and Sporadic Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degenerations arising from Pathological Condensates of Phase Separating Proteins.
Michael Fernandopulle, GuoZhen Wang, Jonathon Nixon-Abell, Seema Qamar, Varun Balaji, Ryuta Morihara, Peter H St George-Hyslop
Jul 08, 2019
ANXA11 Amyotrophic Lateral Sclerosis FUS TDP-43 biological condensates fronto-temporal dementia gelation Hydrogels local RNA translation neuronal transport granules phase separation Stress granules Amyotrophic Lateral Sclerosis Annexins Biological Transport DNA-Binding Proteins Frontotemporal Lobar Degeneration Humans Intracellular Membranes Mutation Missense Neurodegenerative Diseases Neurons Protein Processing Post-Translational RNA-Binding Protein FUS Temporal Lobe
Regulation of membrane fluidity by
<scp>RNF145</scp>
‐triggered degradation of the lipid hydrolase
<scp>ADIPOR2</scp>
Norbert Volkmar, Christian M Gawden‐Bone, James C Williamson, Jonathon Nixon‐Abell, James A West, Peter H St George‐Hyslop, Arthur Kaser, Paul J Lehner
Aug 22, 2022
Transcatheter Aortic and Mitral Valve Replacements.
Ryan Wilson, Charis McNabney, Jonathan R Weir-McCall, Stephanie Sellers, Philipp Blanke, Jonathon A Leipsic
Oct 08, 2019
Amid rapid growth in transcatheter valvular interventions computed tomography (CT) has emerged as a pivotal noninvasive imaging resource that can be used throughout many stages of the transcatheter heart valve process, enhancing...
The effect of canopy architecture on the patterning of “windflecks” within a wheat canopy
Alexandra J. Burgess, Maxime Durand, Jonathon A. Gibbs, Renata Retkute, T. Matthew Robson, Erik H. Murchie
Aug 30, 2021
Abstract: Under field conditions, plants are subject to wind‐induced movement which creates fluctuations of light intensity and spectral quality reaching the leaves, defined here as windflecks. Within this study, irradiance...
Original Article Original Articles Light intensity Photosynthesis spectral quality wheat (Triticum aestivum) wind‐induced movement
Published by: John Wiley & Sons, Ltd.
The effect of canopy architecture on the patterning of "windflecks" within a wheat canopy.
Alexandra J Burgess, Maxime Durand, Jonathon A Gibbs, Renata Retkute, T Matthew Robson, Erik H Murchie
Sep 01, 2021
Under field conditions, plants are subject to wind-induced movement which creates fluctuations of light intensity and spectral quality reaching the leaves, defined here as windflecks. Within this study, irradiance within two...
Kinetics versus Charge SeparationSeparation
Oxygen-deficient iron oxide thin films, which have recently been shown to be highly active for photoelectrochemical water oxidation, were surface-functionalized with a monolayer of a molecular iridium water oxidation cocatalyst....
Highlights of the fourteenth annual scientific meeting of the Society of Cardiovascular Computed Tomography.
Jonathan R Weir-McCall, Edward Nicol, Suhny Abbara, Kelley Branch, Andrew D Choi, Brian B Ghoshhajra, Jonathon Leipsic, Koen Nieman, Leslee J Shaw, Ron Blankstein
Sep 28, 2020
The 14th Annual Scientific Meeting of the SCCT, held from July 11 to July 14 in Baltimore, MA, was attended by 830 attendees from 31 countries, with a program that included 45 sessions, and 26 exhibitors. This article summarizes...
Computed tomography imaging in the context of transcatheter aortic valve implantation (TAVI) / transcatheter aortic valve replacement (TAVR)
Philipp Blanke, Jonathan R Weir-McCall, Stephan Achenbach, Victoria Delgado, Jörg Hausleiter, Hasan Jilaihawi, Mohamed Marwan, Bjarne L Norgaard, Niccolo Piazza, Paul Schoenhagen, Jonathon A Leipsic
Feb 07, 2019
Since the publication of the firstexpertconsensus document on computed tomography imaging before transcatheter aortic valve implantation (TAVI)/trans- catheter aortic valve replacement (TAVR) by the So- ciety of Cardiovascular...
The evolving role of preprints in the dissemination of COVID-19 research and their impact on the science communication landscape.
Nicholas Fraser, Liam Brierley, Gautam Dey, Jessica K Polka, Máté Pálfy, Federico Nanni, Jonathon Alexis Coates
Apr 14, 2021
The world continues to face a life-threatening viral pandemic. The virus underlying the Coronavirus Disease 2019 (COVID-19), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has caused over 98 million confirmed...
Self-Organization of Minimal Anaphase Spindle Midzone Bundles.
Jonathon Hannabuss, Manuel Lera-Ramirez, Nicholas I Cade, Franck J Fourniol, François Nédélec, Thomas Surrey
Jul 25, 2019
In anaphase spindles, antiparallel microtubules associate to form tight midzone bundles, as required for functional spindle architecture and correct chromosome segregation. Several proteins selectively bind to these overlaps to...
Compositional Proteomics
Jonathon J O'Brien, Jeremy D O'Connell, Joao A Paulo, Sanjukta Thakurta, Christopher M Rose, Michael P Weekes, Edward L Huttlin, Steven P Gygi
Feb 16, 2018
Mass spectrometry (MS) has become an accessible tool for whole proteome quantitation with the ability to characterize protein expression across thousands of proteins within a single experiment. A subset of MS quantification...
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