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Results: 36
Linking slow dynamics and microscopic connectivity in dense suspensions of charged colloids.
The quest to unravel the nature of the glass transition, where the viscosity of a liquid increases by many orders of magnitude, while its static structure remains largely unaffected, remains unresolved. While various structural...
Assessing the structural heterogeneity of supercooled liquids through community inference.
We present an information-theoretic approach inspired by distributional clustering to assess the structural heterogeneity of particulate systems. Our method identifies communities of particles that share a similar local...
Statistical-Shape Prediction of Lower Limb Kinematics During Cycling, Squatting, Lunging, and Stepping-Are Bone Geometry Predictors Helpful?
Purpose: Statistical shape methods have proven to be useful tools in providing statistical predications of several clinical and biomechanical features as to analyze and describe the possible link with them. In the present study...
Double-label immunohistochemistry to assess labyrinth structure of the mouse placenta with stereology.
In mice, the labyrinth zone of the placenta exchanges nutrients and gases between mother and fetus. This placental zone is complex in structure and defects in its morphogenesis can compromise substrate exchange and thus, fetal...
Does Alcohol Hangover Affect Emotion Regulation Capacity? Evidence from a Naturalistic Cross-Over Study Design
Aims
The aim of this study was to investigate the effects of alcohol hangover on emotion regulation.
Methods
Forty-five non-smoking, healthy participants aged between 18 and 30 years completed a lab-based...
The aim of this study was to investigate the effects of alcohol hangover on emotion regulation.
Methods
Forty-five non-smoking, healthy participants aged between 18 and 30 years completed a lab-based...
Mapping the expression of transient receptor potential channels across murine placental development
Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens
Jun 26, 2021
Statistical Modeling of Lower Limb Kinetics During Deep Squat and Forward Lunge.
PURPOSE: Modern statistics and higher computational power have opened novel possibilities to complex data analysis. While gait has been the utmost described motion in quantitative human motion analysis, descriptions of more...
Mapping the expression of transient receptor potential channels across murine placental development.
Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens
Jul 07, 2021
placental development Primary trophoblast cells TRP channels trophoblast stem cells Animals Calcium Channels Calcium Signaling Cell Differentiation Cell Proliferation Female Gene Expression Regulation Mice Mice Inbred C57BL Mouse embryonic stem cells Placenta Placentation Pregnancy Stem Cells TRPV Cation Channels Transient Receptor Potential Channels Trophoblasts
Does Alcohol Hangover Affect Emotion Regulation Capacity? Evidence from a Naturalistic Cross-Over Study Design
Aims
The aim of this study was to investigate the effects of alcohol hangover on emotion regulation.
Methods
Forty-five non-smoking, healthy participants aged between 18 and 30 years completed a lab-based...
The aim of this study was to investigate the effects of alcohol hangover on emotion regulation.
Methods
Forty-five non-smoking, healthy participants aged between 18 and 30 years completed a lab-based...
Neuroserpin Inclusion Bodies in a FENIB Yeast Model.
Valentina Vapore, Corrado Mazzaglia, Diego Sibilia, Mara Del Vecchio, Gernot Fruhmann, Marta Valenti, Elena Miranda, Teresa Rinaldi, Joris Winderickx, Cristina Mazzoni
Jul 28, 2021
FENIB (familial encephalopathy with neuroserpin inclusion bodies) is a human monogenic disease caused by point mutations in the SERPINI1 gene, characterized by the intracellular deposition of polymers of neuroserpin (NS), which...
Inferring Allele Frequency Trajectories from Ancient DNA Indicates That Selection on a Chicken Gene Coincided with Changes in Medieval Husbandry Practices
Pioneering Net Zero Carbon Construction Policy in Bath & North East Somerset
Joris Simaitis, Will Hawkins, Andrew Shea, Stephen Allen, Ellie Marsh, Peter Phelps, Alice Barnes, Richard Daone, Alex McCann, Alex Bell, Elli Nikolaidou
Oct 20, 2023
A pilot study run by the University of Bath in partnership with Bath & North East Somerset Council, Chapter2 Architects and the South West Net Zero Hub
Published by: University of Bath
Pioneering Net Zero Carbon Construction Policy in Bath & North East Somerset
Joris Simaitis, Will Hawkins, Andrew Shea, Stephen Allen, Ellie Marsh, Peter Phelps, Alice Barnes, Richard Daone, Alex McCann, Alex Bell, Elli Nikolaidou
Oct 20, 2023
A pilot study run by the University of Bath in partnership with Bath & North East Somerset Council, Chapter2 Architects and the South West Net Zero Hub
Published by: University of Bath
AP4 deficiency
Agathe Roubertie, Nelson Hieu, Charles-Joris Roux, Nicolas Leboucq, Gael Manes, Majida Charif, Bernard Echenne, Cyril Goizet, Claire Guissart, Pierre Meyer, Cecilia Marelli, François Rivier, Lydie Burglen, Rita Horvath, Christian P Hamel, Guy Lenaers
Oct 01, 2019
OBJECTIVE: To describe the clinico-radiological phenotype of 3 patients harboring a homozygous novel AP4M1 pathogenic mutation. METHODS: The 3 patients from an inbred family who exhibited early-onset developmental delay...
Recommendations for hemodynamic monitoring for critically ill children-expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).
Yogen Singh, Javier Urbano Villaescusa, Eduardo M da Cruz, Shane M Tibby, Gabriella Bottari, Rohit Saxena, Marga Guillén, Jesus Lopez Herce, Matteo Di Nardo, Corrado Cecchetti, Joe Brierley, Willem de Boode, Joris Lemson
Oct 22, 2021
BACKGROUND: Cardiovascular instability is common in critically ill children. There is a scarcity of published high-quality studies to develop meaningful evidence-based hemodynamic monitoring guidelines and hence, with the...
Recommendations for hemodynamic monitoring for critically ill children—expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC)
Yogen Singh, Javier Urbano Villaescusa, Eduardo M. da Cruz, Shane M. Tibby, Gabriella Bottari, Rohit Saxena, Marga Guillén, Jesus Lopez Herce, Matteo Di Nardo, Corrado Cecchetti, Joe Brierley, Willem de Boode, Joris Lemson
Oct 22, 2020
Abstract: Background: Cardiovascular instability is common in critically ill children. There is a scarcity of published high-quality studies to develop meaningful evidence-based hemodynamic monitoring guidelines and hence, with...
Sex-specific associations between potassium intake, blood pressure, and cardiovascular outcomes
Rosa D Wouda, S Matthijs Boekholdt, Kay Tee Khaw, Nicholas J Wareham, Martin H de Borst, Ewout J Hoorn, Joris I Rotmans, Liffert Vogt
Aug 21, 2022
WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming.
Georgina Peñalosa-Ruiz, Vicky Bousgouni, Jan P Gerlach, Susan Waarlo, Joris V van de Ven, Tim E Veenstra, José CR Silva, Simon J van Heeringen, Chris Bakal, Klaas W Mulder, Gert Jan C Veenstra
Mar 29, 2019
Caring for patients with cancer in the COVID-19 era.
Joris van de Haar, Louisa R Hoes, Charlotte E Coles, Kenneth Seamon, Stefan Fröhling, Dirk Jäger, Franco Valenza, Filippo de Braud, Luigi De Petris, Jonas Bergh, Ingemar Ernberg, Benjamin Besse, Fabrice Barlesi, Elena Garralda, Alejandro Piris-Giménez, Michael Baumann, Giovanni Apolone, Jean Charles Soria, Josep Tabernero, Carlos Caldas, Emile E Voest
May 13, 2020
The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising...
Chromosomal copy number heterogeneity predicts survival rates across cancers
Erik van Dijk, Tom van den Bosch, Kristiaan J. Lenos, Khalid El Makrini, Lisanne E. Nijman, Hendrik F. B. van Essen, Nico Lansu, Michiel Boekhout, Joris H. Hageman, Rebecca C. Fitzgerald, Cornelis J. A. Punt, Jurriaan B. Tuynman, Hugo J. G. Snippert, Geert J. P. L. Kops, Jan Paul Medema, Bauke Ylstra, Louis Vermeulen, Daniël M. Miedema
May 27, 2021
Chromosomal copy number heterogeneity predicts survival rates across cancers.
Erik van Dijk, Tom van den Bosch, Kristiaan J Lenos, Khalid El Makrini, Lisanne E Nijman, Hendrik FB van Essen, Nico Lansu, Michiel Boekhout, Joris H Hageman, Rebecca C Fitzgerald, Cornelis JA Punt, Jurriaan B Tuynman, Hugo JG Snippert, Geert JPL Kops, Jan Paul Medema, Bauke Ylstra, Louis Vermeulen, Daniël M Miedema
Jul 09, 2021
Survival rates of cancer patients vary widely within and between malignancies. While genetic aberrations are at the root of all cancers, individual genomic features cannot explain these distinct disease outcomes. In contrast...
Adolescent Adult Aged Aged 80 and over Child Computer Simulation DNA Copy Number Variations Datasets as Topic Female Gene Expression Profiling Gene Expression Regulation Neoplastic Genetic Heterogeneity Genomics Humans Male Middle Aged Models Genetic Mutation Neoplasms Prognosis Progression-Free Survival Risk Assessment Survival Rate Tumor Microenvironment Young Adult
Chromosomal copy number heterogeneity predicts survival rates across cancers.
Erik van Dijk, Tom van den Bosch, Kristiaan J Lenos, Khalid El Makrini, Lisanne E Nijman, Hendrik F B van Essen, Nico Lansu, Michiel Boekhout, Joris H Hageman, Rebecca C Fitzgerald, Cornelis J A Punt, Jurriaan B Tuynman, Hugo J G Snippert, Geert J P L Kops, Jan Paul Medema, Bauke Ylstra, Louis Vermeulen, Daniël M Miedema
Jun 28, 2021
Humans Neoplasms Prognosis Survival Rate Risk Assessment Gene Expression Profiling Genomics Gene Expression Regulation Neoplastic Genetic Heterogeneity Mutation Models Genetic Computer Simulation Adolescent Adult Aged Aged 80 and over Middle Aged Child Female Male Young Adult DNA Copy Number Variations Tumor Microenvironment Datasets as Topic Progression-Free Survival
Published by: Nature Communications
Somatic variants in autosomal dominant genes are a rare cause of sporadic Alzheimer's disease.
Gaël Nicolas, Rocío Acuña-Hidalgo, Michael J Keogh, Olivier Quenez, Marloes Steehouwer, Stefan Lelieveld, Stéphane Rousseau, Anne-Claire Richard, Manon S Oud, Florent Marguet, Annie Laquerrière, Chris M Morris, Johannes Attems, Colin Smith, Olaf Ansorge, Safa Al Sarraj, Thierry Frebourg, Dominique Campion, Didier Hannequin, David Wallon, Christian Gilissen, Patrick F Chinnery, Joris A Veltman, Alexander Hoischen
Oct 03, 2018
INTRODUCTION: A minority of patients with sporadic early-onset Alzheimer's disease (AD) exhibit de novo germ line mutations in the autosomal dominant genes such as APP, PSEN1, or PSEN2. We hypothesized that negatively screened...
A global analysis of the impact of COVID-19 stay-at-home restrictions on crime.
Amy E Nivette, Renee Zahnow, Raul Aguilar, Andri Ahven, Shai Amram, Barak Ariel, María José Arosemena Burbano, Roberta Astolfi, Dirk Baier, Hyung-Min Bark, Joris EH Beijers, Marcelo Bergman, Gregory Breetzke, I Alberto Concha-Eastman, Sophie Curtis-Ham, Ryan Davenport, Carlos Díaz, Diego Fleitas, Manne Gerell, Kwang-Ho Jang, Juha Kääriäinen, Tapio Lappi-Seppälä, Woon-Sik Lim, Rosa Loureiro Revilla, Lorraine Mazerolle, Gorazd Meško, Noemí Pereda, Maria FT Peres, Rubén Poblete-Cazenave, Simon Rose, Robert Svensson, Nico Trajtenberg, Tanja van der Lippe, Joran Veldkamp, Carlos J Vilalta Perdomo, Manuel P Eisner
Jun 22, 2021
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