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Results: 1496
OLIG2 is differentially expressed in pediatric astrocytic and in ependymal neoplasms.
The bHLH transcription factor, OLIG2, is universally expressed in adult human gliomas and, as a major factor in the development of oligodendrocytes, is expressed at the highest levels in low-grade oligodendroglial tumors. In...
EMD-based data augmentation method applied to handwriting data for the diagnosis of Essential Tremor using LSTM networks.
José Fernando Adrán Otero, Karmele López-de-Ipina, Oscar Solans Caballer, Pere Marti-Puig, José Ignacio Sánchez-Méndez, Jon Iradi, Alberto Bergareche, Jordi Solé-Casals
Jul 27, 2022
The increasing capacity of today's technology represents great advances in diagnosing diseases using standard procedures supported by computer science. Deep learning techniques are able to extract the characteristics of temporal...
EMD-based data augmentation method applied to handwriting data for the diagnosis of Essential Tremor using LSTM networks.
José Fernando Adrán Otero, Karmele López-de-Ipina, Oscar Solans Caballer, Pere Marti-Puig, José Ignacio Sánchez-Méndez, Jon Iradi, Alberto Bergareche, Jordi Solé-Casals
Sep 02, 2022
The increasing capacity of today's technology represents great advances in diagnosing diseases using standard procedures supported by computer science. Deep learning techniques are able to extract the characteristics of temporal...
Clinical, Virological and Immunological Responses after Experimental Infection with African Horse Sickness Virus Serotype 9 in Immunologically Naïve and Vaccinated Horses.
Manuel Durán-Ferrer, Rubén Villalba, Paloma Fernández-Pacheco, Cristina Tena-Tomás, Miguel-Ángel Jiménez-Clavero, José-Antonio Bouzada, María-José Ruano, Jovita Fernández-Pinero, Marisa Arias, Javier Castillo-Olivares, Montserrat Agüero
Jul 19, 2022
This study described the clinical, virological, and serological responses of immunologically naïve and vaccinated horses to African horse sickness virus (AHSV) serotype 9. Naïve horses developed a clinical picture resembling the...
Dictyostelium transcriptional responses to Pseudomonas aeruginosa
Sergio Carilla-Latorre, Javier Calvo-Garrido, Gareth Bloomfield, Jason Skelton, Robert R Kay, Alasdair Ivens, José L Martinez, Ricardo Escalante
Jun 14, 2011
Clinical, Virological and Immunological Responses after Experimental Infection with African Horse Sickness Virus Serotype 9 in Immunologically Naïve and Vaccinated Horses.
Manuel Durán-Ferrer, Rubén Villalba, Paloma Fernández-Pacheco, Cristina Tena-Tomás, Miguel-Ángel Jiménez-Clavero, José-Antonio Bouzada, María-José Ruano, Jovita Fernández-Pinero, Marisa Arias, Javier Castillo-Olivares, Montserrat Agüero
Sep 02, 2022
This study described the clinical, virological, and serological responses of immunologically naïve and vaccinated horses to African horse sickness virus (AHSV) serotype 9. Naïve horses developed a clinical picture resembling the...
Phosphoinositide 3-kinase beta controls replication factor C assembly and function.
Javier Redondo-Muñoz, María Josefa Rodríguez, Virginia Silió, Vicente Pérez-García, José María Valpuesta, Ana C Carrera
Apr 16, 2019
Genomic integrity is preserved by the action of protein complexes that control DNA homeostasis. These include the sliding clamps, trimeric protein rings that are arranged around DNA by clamp loaders. Replication factor C (RFC)...
Writing 3D Nanomagnets Using Focused Electron Beams.
Amalio Fernández-Pacheco, Luka Skoric, José María De Teresa, JAVIER PABLO-NAVARRO, Michael Huth, Oleksandr V Dobrovolskiy
Aug 27, 2020
Focused electron beam induced deposition (FEBID) is a direct-write nanofabrication technique able to pattern three-dimensional magnetic nanostructures at resolutions comparable to the characteristic magnetic length scales. FEBID...
E-Assessment and Multiple-Choice Questions
The use of information and communication technologies (ICT) in the assessment process is becoming an asset, giving rise to the so-called computer-based assessment or e-assessment. Nowadays, its use is becoming more usual in...
Published by: IGI Global Scientific Publishing
Dynamics of chromatin accessibility and gene regulation by MADS-domain transcription factors in flower development.
Alice Pajoro, Pedro Madrigal, Jose M Muiño, José Tomás Matus, Jian Jin, Martin A Mecchia, Juan M Debernardi, Javier F Palatnik, Salma Balazadeh, Muhammad Arif, Diarmuid S Ó'Maoiléidigh, Frank Wellmer, Pawel Krajewski, José-Luis Riechmann, Gerco C Angenent, Kerstin Kaufmann
Jun 19, 2020
BACKGROUND: Development of eukaryotic organisms is controlled by transcription factors that trigger specific and global changes in gene expression programs. In plants, MADS-domain transcription factors act as master regulators...
Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.
Sara Ruiz-Pinto, Guillermo Pita, Miguel Martín, Teresa Alonso-Gordoa, Daniel R Barnes, María R Alonso, Belén Herraez, Purificación García-Miguel, Javier Alonso, Antonio Pérez-Martínez, Antonio J Cartón, Federico Gutiérrez-Larraya, José A García-Sáenz, Javier Benítez, Douglas F Easton, Ana Patiño-García, Anna González-Neira
Jan 30, 2018
PURPOSE: Anthracyclines are widely used chemotherapeutic drugs that can cause progressive and irreversible cardiac damage and fatal heart failure. Several genetic variants associated with anthracycline-induced cardiotoxicity...
Anthracyclines Chronic cardiotoxicity ETFB Long-term cancer survivors Low-frequency variants Adult Aged Anthracyclines Breast Neoplasms Cancer Survivors Cardiotoxicity Electron-Transferring Flavoproteins Exome Female Gene Expression Regulation Neoplastic Genetic Association Studies Genetic Predisposition to Disease Heart Failure Humans Middle Aged Mitochondria
A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis.
Raquel López-Mejías, F David Carmona, Santos Castañeda, Fernanda Genre, Sara Remuzgo-Martínez, Belén Sevilla-Perez, Norberto Ortego-Centeno, Javier Llorca, Begoña Ubilla, Verónica Mijares, Trinitario Pina, José A Miranda-Filloy, Antonio Navas Parejo, Diego de Argila, Maximiliano Aragües, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Aguirregoikoa, David Jayne, Ricardo Blanco, Javier Martín, Miguel A González-Gay
Feb 24, 2020
The genetic component of Immunoglobulin-A (IgA) vasculitis is still far to be elucidated. To increase the current knowledge on the genetic component of this vasculitis we performed the first genome-wide association study (GWAS)...
Role of DNA-detection-based tools for monitoring the soil-transmitted helminth treatment response in drug-efficacy trials.
Javier Gandasegui, María Martínez-Valladares, Berta Grau-Pujol, Alejandro J Krolewiecki, Rafael Balaña-Fouce, Woyneshet Gelaye, Lisette van Lieshout, Stella Kepha, Inácio Mandomando, José Muñoz, Stopping Transmission Of intestinal Parasites (STOP) project consortium
Feb 06, 2020
Freedom of Expression, Privacy, and Ethical and Social Responsibility in Democracy in the Digital Age
José Rascão
Jul 01, 2020
This article reflects on freedom of expression, privacy, ethical and social responsibility, in the context of social networks, in the context of the experience of democracy in cyberspace. It asks questions about ensuring the...
Published by: IGI Global Scientific Publishing
Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes.
Andrés García-García, Claudia Korn, María García-Fernández, Olivia Domingues, Javier Villadiego, Daniel Martín-Pérez, Joan Isern, José A Bejarano-García, Jacques Zimmer, José A Pérez-Simón, Juan J Toledo-Aral, Tatiana Michel, Matti S Airaksinen, Simón Méndez-Ferrer
Dec 07, 2018
Hematopoietic stem and progenitor cells (HSPCs) and leukocytes circulate between the bone marrow (BM) and peripheral blood following circadian oscillations. Autonomic sympathetic noradrenergic signals have been shown to regulate...
Animals Bone Marrow Cells Cell Adhesion Cell Movement Cells Cultured Chemotaxis Cholinergic Agents Circadian Rhythm Endothelium Vascular Female Glial Cell Line-Derived Neurotrophic Factor Receptors Hematopoietic Stem Cells Leukocytes Male Mice Mice Inbred C57BL Mice Knockout Parasympathetic Nervous System Receptors Adrenergic beta-2 Receptors Adrenergic beta-3 Receptors G-Protein-Coupled sympathetic nervous system
Impact of Brand Trust and Technology Readiness on the Willingness to Use Autonomous Cars in Brazil
This study sought to analyse whether brand trust and technology readiness influence the willingness to use (WTU) autonomous vehicles (AVs) in Brazil. A survey was applied with potential consumers, and the results, based on 213...
Published by: IGI Global Scientific Publishing
The Value of Economic Information in the Digital Society
José Rascão
Jan 01, 2021
In the contemporary organizational context, the sharing and transfer of information and knowledge plays a significant role. What can be facilitated with the emerging interdisciplinary approach, which crosses the fieldsof...
Global Information Technology Computer Science and Information Technology Global Information Technology
Published by: IGI Global Scientific Publishing
Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome.
Hiroko Nobuta, Maria Roberta Cilio, Olivier Danhaive, Hui-Hsin Tsai, Srinivasan Tupal, Sandra M Chang, Alice Murnen, Faith Kreitzer, Verenice Bravo, Catherine Czeisler, Hamza Numan Gokozan, Patrick Gygli, Sean Bush, Debra E Weese-Mayer, Bruce Conklin, Siu-Pok Yee, Eric J Huang, Paul A Gray, David Rowitch, José Javier Otero
Dec 06, 2017
Human congenital central hypoventilation syndrome (CCHS), resulting from mutations in transcription factor PHOX2B, manifests with impaired responses to hypoxemia and hypercapnia especially during sleep. To identify brainstem...
Organizational Ecology and Its Implications on Organizational Ecological Innovation
This study has the objective to analyze the implications of the organizational ecology on organizational ecological innovation from the assumption that the theoretical and conceptual framework of organizational ecology is...
Published by: IGI Global Scientific Publishing
Virtual Interface With Kinect 3D Sensor for Interaction With Bedridden People
The human-machine interaction has evolved significantly in the last years, allowing a new range of opportunities for developing solutions for people with physical limitations. Natural user interfaces (NUI) allow bedridden and/or...
Published by: IGI Global Scientific Publishing
Predicting the Success of a Startup in Information Technology Through Machine Learning
Predicting the success of a startup in information technology (SIT) is a very complex problem due to the diverse factors and uncertainty that affects it. The focus of automatic learning (ML) is promising because it presents good...
Published by: IGI Global Scientific Publishing
POSEIDON Trial Phase 1b Results
Richard D Baird, Annelot GJ van Rossum, Mafalda Oliveira, Karin Beelen, Meiling Gao, Mariette Schrier, Ingrid AM Mandjes, Javier Garcia-Corbacho, Anne-Laure Vallier, Greig Dougall, Erik Van Werkhoven, Constanza Linossi, Sanjeev Kumar, Harm van Tinteren, Maurizio Callari, Emma Beddowes, José-Manuel Perez-Garcia, Hilde Rosing, Else Platte, Petra Nederlof, Margaret Schot, Aurelia de Vries Schultink, René Bernards, Cristina Saura, William Gallagher, Javier Cortès, Carlos Caldas, Sabine C Linn
Oct 02, 2019
PURPOSE: The strategy of combining endocrine therapy with PI3K-mTOR inhibition has shown promise in estrogen receptor (ER)-positive breast cancer, but new agents and combinations with a better therapeutic index are urgently...
Adult Aged Aged 80 and over Antineoplastic Combined Chemotherapy Protocols Biomarkers Tumor Breast Neoplasms Circulating Tumor DNA Female Humans Imidazoles Middle Aged Mutation Neoplasm Metastasis Neoplasm Staging Oxazepines Receptors Estrogen Receptors Progesterone Retreatment Tamoxifen Treatment Outcome
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