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Results: 38
Methylation of the C19MC microRNA locus in the placenta
Anna Prats-Puig, Sílvia Xargay-Torrent, Gemma Carreras-Badosa, Berta Mas-Parés, Judit Bassols, Clive J Petry, Michael Girardot, Francis D E Zegher, Lourdes Ibáñez, David B Dunger, Robert Feil, Abel López-Bermejo
Jul 12, 2019
Codon Usage and Adenovirus Fitness
Judit Giménez-Roig, Estela Núñez-Manchón, Ramon Alemany, Eneko Villanueva, Cristina Fillat
Feb 24, 2021
Vaccination is the most effective method to date to prevent viral diseases. It intends to mimic a naturally occurring infection while avoiding the disease, exposing our bodies to viral antigens to trigger an immune response that...
A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules.
Substitution of the native <i>srfA</i> promoter by constitutive P<i>veg</i> in two <i>B. subtilis </i>strains and evaluation of the effect on surfactin production
Judit Willenbacher, Teresa Mohr, Marius Henkel, Susanne Gebhard, Thorsten Mascher, Christoph Syldatk, Rudolf Hausmann
Apr 01, 2016
The genetic enhancement of Surfactin production increasingly gained attention in the last years, since relatively low product yields limit the industrial application of this biosurfactant. The natural quorum sensing regulation...
Global and Multiplexed Dendritic Computations under In Vivo-like Conditions.
Dendrites integrate inputs nonlinearly, but it is unclear how these nonlinearities contribute to the overall input-output transformation of single neurons. We developed statistically principled methods using a hierarchical...
Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis
Abstract Inactivation of the VHL (Von Hippel Lindau) tumour suppressor has long been recognised as necessary for the pathogenesis of clear cell renal cancer (ccRCC);...
Unsupervised Machine Learning to Identify Positive and Negative Themes in Jordanian mHealth Apps
User opinions are crucial in the development of mobile health (mHealth) applications (apps). This study aimed to investigate and qualitatively assess consumer attitudes toward mHealth apps and the main aspects of their design....
Published by: IGI Global Scientific Publishing
Validation study of the Spanish version of the Last-7-d Sedentary Time Questionnaire (SIT-Q-7d-Sp) in young adults.
Mireia Felez-Nobrega, Judit Bort-Roig, Kieran P Dowd, Katrien Wijndaele, Anna Puig-Ribera
May 23, 2019
Substitution of the native <i>srfA</i> promoter by constitutive P<i>veg</i> in two <i>B. subtilis </i>strains and evaluation of the effect on surfactin production
Judit Willenbacher, Teresa Mohr, Marius Henkel, Susanne Gebhard, Thorsten Mascher, Christoph Syldatk, Rudolf Hausmann
Apr 01, 2016
The genetic enhancement of Surfactin production increasingly gained attention in the last years, since relatively low product yields limit the industrial application of this biosurfactant. The natural quorum sensing regulation...
Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells.
Judit Espana-Agusti, Xiangang Zou, Kim Wong, Beiyuan Fu, Fengtang Yang, David A Tuveson, David J Adams, Athena Matakidou
Feb 09, 2016
Animals Chromosomes Artificial Bacterial Epithelial Cells Estrogen Receptor alpha Female Gene Deletion Gene Knock-In Techniques Genotype Hypoxia Immunohistochemistry In Situ Hybridization Fluorescence Integrases Kidney Tubules Male Mice Mice Inbred C57BL Mice Transgenic Organic Anion Transport Protein 1 PAX8 Transcription Factor Paired Box Transcription Factors Sequence Analysis DNA Tamoxifen Transgenes
The IBER study
Craig Steel, Kim Wright, Guy Goodwin, Judit Simon, Nicola Morant, Rod Taylor, Michael Brown, Susie Jennings, Susie Hales, Emily Holmes
Jun 15, 2021
BACKGROUND: Anxiety is highly prevalent in people diagnosed with bipolar disorder (BD), and can persist between acute episodes of mania and depression. Recent studies indicate that people with BD are prone to experiencing...
The IBER study
Craig Steel, Kim Wright, Guy Goodwin, Judit Simon, Nicola Morant, Rod Taylor, Michael Brown, Susie Jennings, Susie Hales, Emily Holmes
Jun 15, 2020
Abstract: Background: Anxiety is highly prevalent in people diagnosed with bipolar disorder (BD), and can persist between acute episodes of mania and depression. Recent studies indicate that people with BD are prone to...
P(I) Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5).
Emily V Wong, Wenxiang Cao, Judit Vörös, Monique Merchant, Yorgo Modis, David D Hackney, Ben Montpetit, Enrique M De La Cruz
Mar 03, 2016
Proteomic analysis of meiosis and characterization of novel short open reading frames in the fission yeast Schizosaccharomyces pombe.
Barbora Huraiova, Judit Kanovits, Silvia Bagelova Polakova, Lubos Cipak, Zsigmond Benko, Andrea Sevcovicova, Dorothea Anrather, Gustav Ammerer, Caia DS Duncan, Juan Mata, Juraj Gregan
Jun 10, 2020
Meiosis is the process by which haploid gametes are produced from diploid precursor cells. We used stable isotope labeling by amino acids in cell culture (SILAC) to characterize the meiotic proteome in the fission yeast...
PIGO deficiency
Marie-Anne Morren, Jaak Jaeken, Gepke Visser, Isabelle Salles, Chris van Geet, NIHR BioResource, Ilenia Simeoni, Ernest Turro Bassols, Kathleen Freson
May 31, 2018
NIHR BioResource Humans Keratoderma Palmoplantar Glycosylphosphatidylinositols Membrane Proteins Mutation Adolescent Male
Published by: Orphanet journal of rare diseases
The State of Migratory Landbirds in the East Asian Flyway
Ding Li Yong, Wieland Heim, Sayam U. Chowdhury, Chang-Yong Choi, Pavel Ktitorov, Olga Kulikova, Alexander Kondratyev, Philip D. Round, Desmond Allen, Colin R. Trainor, Luke Gibson, Judit K. Szabo
Apr 27, 2021
With nearly 400 migratory landbird species, the East Asian Flyway is the most diverse of the world’s flyways. This diversity is a consequence of the varied ecological niches provided by biomes ranging from broadleaf forests to...
Following "the Roots" of Kratom (Mitragyna speciosa)
Eduardo Cinosi, Giovanni Martinotti, Pierluigi Simonato, Darshan Singh, Zsolt Demetrovics, Andres Roman-Urrestarazu, Francesco Saverio Bersani, Balasingam Vicknasingam, Giulia Piazzon, Jih-Heng Li, Wen-Jing Yu, Máté Kapitány-Fövény, Judit Farkas, Massimo Di Giannantonio, Ornella Corazza
Oct 03, 2017
P(I) Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5).
Emily V Wong, Wenxiang Cao, Judit Vörös, Monique Merchant, Yorgo Modis, David D Hackney, Ben Montpetit, Enrique M De La Cruz
Aug 09, 2017
Ankk1 Loss of Function Disrupts Dopaminergic Pathways in Zebrafish.
Adele Leggieri, Judit García-González, Jose V Torres-Perez, William Havelange, Saeedeh Hosseinian, Aleksandra M Mech, Marcus Keatinge, Elisabeth M Busch-Nentwich, Caroline H Brennan
Feb 22, 2022
Ankyrin repeat and kinase domain containing 1 (ANKK1) is a member of the receptor-interacting protein serine/threonine kinase family, known to be involved in cell proliferation, differentiation and activation of transcription...
Following "the Roots" of Kratom (Mitragyna speciosa)
Eduardo Cinosi, Giovanni Martinotti, Pierluigi Simonato, Darshan Singh, Zsolt Demetrovics, Andres Roman-Urrestarazu, Francesco Saverio Bersani, Balasingam Vicknasingam, Giulia Piazzon, Jih-Heng Li, Wen-Jing Yu, Máté Kapitány-Fövény, Judit Farkas, Massimo Di Giannantonio, Ornella Corazza
Nov 05, 2018
APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.
Manikandan Periyasamy, Hetal Patel, Chun-Fui Lai, Van TM Nguyen, Ekaterina Nevedomskaya, Alison Harrod, Roslin Russell, Judit Remenyi, Anna Maria Ochocka, Ross S Thomas, Frances Fuller-Pace, Balázs Győrffy, Carlos Caldas, Naveenan Navaratnam, Jason S Carroll, Wilbert Zwart, R Charles Coombes, Luca Magnani, Laki Buluwela, Simak Ali
May 02, 2019
Estrogen receptor α (ERα) is the key transcriptional driver in a large proportion of breast cancers. We report that APOBEC3B (A3B) is required for regulation of gene expression by ER and acts by causing C-to-U deamination at ER...
Binding Sites Breast Neoplasms Cell Line Tumor Cell Proliferation Cytidine Cytidine Deaminase DNA DNA Damage DNA End-Joining Repair Deamination Estrogen Receptor alpha Female Gene Expression Regulation Neoplastic Humans Minor Histocompatibility Antigens Prognosis Protein Binding RNA Small Interfering Signal Transduction Survival Analysis Transcription Genetic Trefoil Factor-1 Tumor Suppressor Proteins
The Obemat2.0 Study
Veronica Luque, Albert Feliu, Joaquín Escribano, Natalia Ferré, Gemma Flores, Raquel Monné, Desirée Gutiérrez-Marín, Núria Guillen, Judit Muñoz-Hernando, Marta Zaragoza-Jordana, Mariona Gispert-Llauradó, Carme Rubio-Torrents, Mercè Núñez-Roig, Mireia Alcázar, Raimon Ferré, Josep M Basora, Pablo Hsu, Clara Alegret-Basora, Francesc Arasa, Michelle Venables, Priya Singh, Ricardo Closa-Monasterolo
Oct 14, 2019
The primary aim of the Obemat2.0 trial was to evaluate the efficacy of a multicomponent motivational program for the treatment of childhood obesity, coordinated between primary care and hospital specialized services, compared to...
Childhood obesity motivational interview obesity treatment PRIMARY CARE Adolescent Body Mass Index Child Cluster Analysis Diet Exercise Female Humans Male Motivational interviewing Patient Education as Topic Pediatric Obesity Psychotherapy Group Spain Telemedicine Treatment Adherence and Compliance Treatment Outcome Waist Circumference
Validation of bioelectrical impedance analysis for body composition assessment in children with obesity aged 8-14y.
Desirée Gutiérrez-Marín, Joaquin Escribano, Ricardo Closa-Monasterolo, Natalia Ferré, Michelle Venables, Priya Singh, Jonathan CK Wells, Judit Muñoz-Hernando, Marta Zaragoza-Jordana, Mariona Gispert-Llauradó, Carme Rubio-Torrents, Mireia Alcázar, Mercè Núñez-Roig, Albert Feliu, Josep Basora, Rosa González-Hidalgo, Mónica Diéguez, Olga Salvadó, Ana Pedraza, Veronica Luque
Feb 05, 2021
BACKGROUND & AIMS: The aim was to generate a predictive equation to assess body composition (BC) in children with obesity using bioimpedance (BIA), and avoid bias produced by different density levels of fat free mass (FFM) in...
Bioelectrical impedance Body composition Childhood obesity Fat free mass Fat mass Validation Studies Absorptiometry Photon Adolescent Anthropometry Body composition Body Water Child Cross-Sectional Studies Electric Impedance Female Humans Indicator Dilution Techniques Male Pediatric Obesity Plethysmography Predictive Value of Tests Randomized Controlled Trials as Topic Reproducibility of Results
Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour.
Judit García-González, Alistair J Brock, Matthew O Parker, Riva J Riley, David Joliffe, Ari Sudwarts, Muy-Teck Teh, Elisabeth M Busch-Nentwich, Derek L Stemple, Adrian R Martineau, Jaakko Kaprio, Teemu Palviainen, Valerie Kuan, Robert T Walton, Caroline H Brennan
May 18, 2020
To facilitate smoking genetics research we determined whether a screen of mutagenized zebrafish for nicotine preference could predict loci affecting smoking behaviour. From 30 screened F3 sibling groups, where each was derived...
acoustic startle conditioned place preference gene association neuroscience Nicotine slit3 Smoking Zebrafish Amisulpride Animals Bupropion Choice Behavior Conditioning Classical Female Genetic Loci Humans Intracellular Signaling Peptides and Proteins Male Membrane Proteins Mutation Nicotine Polymorphism Single Nucleotide Receptor Serotonin 5-HT1A tobacco smoking Zebrafish Zebrafish Proteins
Performance of Breast Cancer Polygenic Risk Scores in 760 Female CHEK2 Germline Mutation Carriers.
Julika Borde, Corinna Ernst, Barbara Wappenschmidt, Dieter Niederacher, Konstantin Weber-Lassalle, Gunnar Schmidt, Jan Hauke, Anne S Quante, Nana Weber-Lassalle, Judit Horváth, Esther Pohl-Rescigno, Norbert Arnold, Andreas Rump, Andrea Gehrig, Julia Hentschel, Ulrike Faust, Véronique Dutrannoy, Alfons Meindl, Maria Kuzyakova, Shan Wang-Gohrke, Bernhard HF Weber, Christian Sutter, Alexander E Volk, Olga Giannakopoulou, Andrew Lee, Christoph Engel, Marjanka K Schmidt, Antonis C Antoniou, Rita K Schmutzler, Karoline Kuchenbaecker, Eric Hahnen
Dec 16, 2020
BACKGROUND: Genome-wide association studies suggest that the combined effects of breast cancer (BC)-associated single nucleotide polymorphisms (SNPs) can improve BC risk stratification using polygenic risk scores (PRSs). The...
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