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Assessment of Aspartate and Bicarbonate Produced From Hyperpolarized [1-13C]Pyruvate as Markers of Renal Gluconeogenesis.
As both a consumer and producer of glucose, the kidney plays a significant role in glucose homeostasis. Measuring renal gluconeogenesis requires invasive techniques, and less invasive methods would allow renal gluconeogenesis to...
Assessment of Aspartate and Bicarbonate Produced From Hyperpolarized [1-13C]Pyruvate as Markers of Renal Gluconeogenesis.
As both a consumer and producer of glucose, the kidney plays a significant role in glucose homeostasis. Measuring renal gluconeogenesis requires invasive techniques, and less invasive methods would allow renal gluconeogenesis to...
Information extraction in emergency management missions
Abstract: With increasing demands for autonomous agents to work alongside
humans in emergency management response (EMR), considerations of
translations of human to machine language (and the converse) are timely....
humans in emergency management response (EMR), considerations of
translations of human to machine language (and the converse) are timely....
Information extraction in emergency management missions
Abstract: With increasing demands for autonomous agents to work alongside
humans in emergency management response (EMR), considerations of
translations of human to machine language (and the converse) are timely....
humans in emergency management response (EMR), considerations of
translations of human to machine language (and the converse) are timely....
Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy.
Dorian Forte, María García-Fernández, Abel Sánchez-Aguilera, Vaia Stavropoulou, Claire Fielding, Daniel Martín-Pérez, Juan Antonio López, Ana SH Costa, Laura Tronci, Efterpi Nikitopoulou, Michael Barber, Paolo Gallipoli, Ludovica Marando, Carlos López Fernández de Castillejo, Alexandar Tzankov, Sabine Dietmann, Michele Cavo, Lucia Catani, Antonio Curti, Jesús Vázquez, Christian Frezza, Brian J Huntly, Juerg Schwaller, Simón Méndez-Ferrer
Sep 03, 2020
OXPHOS TCA cycle acute myeloid leukemia antioxidant bone marrow mesenchymal stem cells Chemotherapy Glutathione hematopoietic stem cell niche metabolic adaptation microenvironment Animals Antineoplastic Agents antioxidants Bone Marrow Cells Cultured Energy Metabolism Female Humans Leukemia Myeloid Acute Male Mesenchymal Stem Cells Mice Mice Inbred C57BL Middle Aged
Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia.
Cécile K Lopez, Esteve Noguera, Vaia Stavropoulou, Elie Robert, Zakia Aid, Paola Ballerini, Chrystèle Bilhou-Nabera, Hélène Lapillonne, Fabien Boudia, Cécile Thirant, Alexandre Fagnan, Marie-Laure Arcangeli, Sarah J Kinston, M'Boyba Diop, Bastien Job, Yann Lecluse, Erika Brunet, Loélia Babin, Jean Luc Villeval, Eric Delabesse, Antoine HFM Peters, William Vainchenker, Muriel Gaudry, Riccardo Masetti, Franco Locatelli, Sébastien Malinge, Claus Nerlov, Nathalie Droin, Camille Lobry, Isabelle Godin, Olivier A Bernard, Berthold Göttgens, Arnaud Petit, Françoise Pflumio, Juerg Schwaller, Thomas Mercher
Nov 25, 2019
Fusion oncogenes are prevalent in several pediatric cancers, yet little is known about the specific associations between age and phenotype. We observed that fusion oncogenes, such as ETO2-GLIS2, are associated with acute...