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Exosomal Protein Deficiencies
Defects of RNA metabolism have been increasingly identified in various forms of inherited neurological diseases. Recently, abnormal RNA degradation due to mutations in human exosome subunit genes has been shown to cause complex...
A Descriptive Account of Victims’ Behaviour and Responses in Sexually Exploitative Interactions with Offenders
Transcripts of chat logs of sexually exploitative interactions between offenders and victims that took place via Internet communication platforms were analysed. The aim of the study was to examine victims’ behaviour and...
Case Studies of Men’s Perceptions of their Online Sexual Interactions with Young People
The aim of the present study was to gain an understanding of the perspectives of men who were convicted of committing a sexual offense that included online sexual grooming. It explores their experiences of illegal interactions...
Internet communication offender experience sexual grooming solicitation /dk/atira/pure/subjectarea/asjc/3200/3200 name=General Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Case Studies of Men’s Perceptions of their Online Sexual Interactions with Young People
The aim of the present study was to gain an understanding of the perspectives of men who were convicted of committing a sexual offense that included online sexual grooming. It explores their experiences of illegal interactions...
Internet communication offender experience sexual grooming solicitation /dk/atira/pure/subjectarea/asjc/3200/3200 name=General Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Modelling Charcot-Marie-Tooth disease in a dish reveals common cell type-specific alterations.
This scientific commentary refers to ‘Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction’, by Van Lent et al. (doi:10.1093/brain/awab226).
Nucleoside supplementation modulates mitochondrial DNA copy number in the dguok -/- zebrafish.
Deoxyguanosine kinase (dGK) is an essential rate-limiting component of the mitochondrial purine nucleotide salvage pathway, encoded by the nuclear gene encoding deoxyguanosine kinase (DGUOK). Mutations in DGUOK lead to...
A Descriptive Account of Victims’ Behaviour and Responses in Sexually Exploitative Interactions with Offenders
Transcripts of chat logs of sexually exploitative interactions between offenders and victims that took place via Internet communication platforms were analysed. The aim of the study was to examine victims’ behaviour and...
The challenges of identifying and classifying child sexual exploitation material
Background: When child sexual exploitation material is seized, digital forensics analysts are required to manually process all “unknown” digital material by determining (a) whether a child is present in the image, and (b)...
Child pornography Child sexual exploitation material Internet sexual offending Online child sexual exploitation and abuse Sexual offenses /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
The challenges of identifying and classifying child sexual exploitation material
Background: When child sexual exploitation material is seized, digital forensics analysts are required to manually process all “unknown” digital material by determining (a) whether a child is present in the image, and (b)...
Child pornography Child sexual exploitation material Internet sexual offending Online child sexual exploitation and abuse Sexual offenses /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Testing the length limit of loop grafting in a helical repeat protein.
Alpha-helical repeat proteins such as consensus-designed tetratricopeptide repeats (CTPRs) are exceptionally stable molecules that are able to tolerate destabilizing sequence alterations and are therefore becoming increasingly...
cD circular dichroism CTPRs consensus-designed tetratricopeptide repeats FcR fraction of charged residues IDPs intrinsically disordered proteins IDRs intrinsically disordered regions Intrinsically Disordered Protein Intrinsically disordered region NCPR net charge per residue PBIP1 polo-box interacting protein 1 Peptide grafting SLiMs short linear motifs TBP tankyrase-binding peptides tandem-repeat protein Tetratricopeptide Repeat ves effective solvation volume
Offense Processes of Online Sexual Grooming and Abuse of Children via Internet Communication Platforms
The aim of the present study was to provide an inclusive and realistic account of the offense processes of naturally occurring, sexually exploitative interactions between offenders and victims that took place via Internet...
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Dimitrios Tsiantoulas, Mahya Eslami, Georg Obermayer, Marc Clement, Diede Smeets, Florian J Mayer, Máté G Kiss, Lennart Enders, Juliane Weißer, Laura Göderle, Jordi Lambert, Florian Frommlet, André Mueller, Tim Hendrikx, Maria Ozsvar-Kozma, Florentina Porsch, Laure Willen, Taras Afonyushkin, Jane E Murphy, Per Fogelstrand, Olivier Donzé, Gerard Pasterkamp, Matthias Hoke, Stefan Kubicek, Helle F Jørgensen, Nicolas Danchin, Tabassome Simon, Hubert Scharnagl, Winfried März, Jan Borén, Henry Hess, Ziad Mallat, Pascal Schneider, Christoph J Binder
Aug 20, 2021
Toxification of polycyclic aromatic hydrocarbons by commensal bacteria from human skin.
Juliane Sowada, Lisa Lemoine, Karsten Schön, Christoph Hutzler, Andreas Luch, Tewes Tralau
Feb 03, 2020
The ubiquitous occurrence of polycyclic aromatic hydrocarbons (PAHs) leads to constant human exposure at low levels. Toxicologically relevant are especially the high-molecular weight substances due to their (pro-)carcinogenic...
Benzo[a]pyrene Cytotoxicity Genotoxicity Microbiome PAHs Polycyclic Aromatic Hydrocarbons Toxification Bacillus licheniformis Cell Line Cell Survival Comet Assay DNA Damage Gas Chromatography-Mass Spectrometry Humans Keratinocytes Metabolic Detoxication Phase I Microbiota Micrococcus luteus Polycyclic Aromatic Hydrocarbons Skin
Offense Processes of Online Sexual Grooming and Abuse of Children via Internet Communication Platforms
The aim of the present study was to provide an inclusive and realistic account of the offense processes of naturally occurring, sexually exploitative interactions between offenders and victims that took place via Internet...
The mutREAD method detects mutational signatures from low quantities of cancer DNA
Juliane Perner, Sujath Abbas, Karol Nowicki-Osuch, Ginny Devonshire, Matthew D. Eldridge, Simon Tavaré, Rebecca C. Fitzgerald
Jun 23, 2021
The mutREAD method detects mutational signatures from low quantities of cancer DNA.
Juliane Perner, Sujath Abbas, Karol Nowicki-Osuch, Ginny Devonshire, Matthew D Eldridge, Simon Tavaré, Rebecca C Fitzgerald
Jun 19, 2020
The mutREAD method detects mutational signatures from low quantities of cancer DNA
Juliane Perner, Sujath Abbas, Karol Nowicki-Osuch, Ginny Devonshire, Matthew D. Eldridge, Simon Tavaré, Rebecca C. Fitzgerald
Jun 23, 2020
Altered RNA metabolism due to a homozygous RBM7 mutation in a patient with spinal motor neuropathy.
Michele Giunta, Shimon Edvardson, Yaobo Xu, Markus Schuelke, Aurora Gomez-Duran, Veronika Boczonadi, Orly Elpeleg, Juliane S Müller, Rita Horvath
Mar 07, 2019
The exosome complex is the most important RNA processing machinery within the cell. Mutations in its subunits EXOSC8 and EXOSC3 cause pontocerebellar hypoplasia, spinal muscular atrophy (SMA) and central nervous system...
A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation.
As modeling becomes a more widespread practice in the life sciences and biomedical sciences, researchers need reliable tools to calibrate models against ever more complex and detailed data. Here we present an approximate...
The Grizzly, March 6, 2008
Matt Flyntz, Lane Taylor, John Strassburger, Ashley McComeskey, Terry Kelley, Kristi Blust, Jill Alspach, Kristin O'Brassill, Juliane Katz, Jeremiah Long, Christopher Schaeffer, Anthony George, Alex Ernst, Matt Short, Laurel Salvo, Ryan Tole, Danielle Langdon
Jan 01, 0001
President Strassburger's Message to Campus About New Member Education Students Flock to Ursinus Job and Internship Fair SIFE: An Organization Suited for All Ursinus Majors The Real Inspector Hound: Stoppard Performed at UC ...
Ursinus College Collegeville Pennsylvania newspaper pledging Steve Bowers community service theater Football Kevin Barger Basketball baseball softball wrestling Steve Kingsland Matt Williams cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, February 7, 2008
Matt Flyntz, Lane Taylor, Megan Helzner, Terry Kelley, Ryan Tole, Ashley Higgins, Ashley McComeskey, Kristi Blust, Roger Lee, Juliane Katz, Jeremiah Long, Christopher Schaeffer, Anthony George, Matt Short, Ashley Drogalis, Jason Davis
Jan 01, 0001
Cafe Owner Advises Mindful Consumerism More Money in Your Pocket? Ledger's Death Still Leaves Questions NY Times Reporter Discusses Climate Issues at Focus the Nation Arctic Mammals Battle Climate Change Modern Menstruation...
Ursinus College Collegeville Pennsylvania newspaper Judy Wicks White Dog Cafe climate change Andrew Revkin Tim Ragen Wismer dining hall Phoenixville Skippack Basketball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Phenotypic convergence of Menkes and Wilson disease.
Boglarka Bansagi, David Lewis-Smith, Endre Pal, Jennifer Duff, Helen Griffin, Angela Pyle, Juliane S Müller, Gabor Rudas, Zsuzsanna Aranyi, Hanns Lochmüller, Patrick F Chinnery, Rita Horvath
Mar 07, 2019
Menkes disease is an X-linked multisystem disorder with epilepsy, kinky hair, and neurodegeneration caused by mutations in the copper transporter ATP7A. Other ATP7A mutations have been linked to juvenile occipital horn syndrome...
The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic.
Alexander M Frankell, Sriganesh Jammula, Xiaodun Li, Gianmarco Contino, Sarah Killcoyne, Sujath Abbas, Juliane Perner, Lawrence Bower, Ginny Devonshire, Emma Ococks, Nicola Grehan, James Mok, Maria O'Donovan, Shona MacRae, Matthew D Eldridge, Simon Tavaré, Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Rebecca C Fitzgerald
Sep 25, 2019
The Grizzly, April 3, 2008
Matt Flyntz, Lane Taylor, Juliane Katz, Terry Kelley, Kristi Blust, Roger Lee, Jeremiah Long, Ashley McComeskey, Kristin O'Brassill, Ryan Tole, Alex Ernst, Laurel Salvo, Matt Short, Jason Davis, Ashley Drogalis, Danielle Langdon
Jan 01, 0001
Crude Awakening: Ways to Beat Surging Gas Pump Prices Airband Turns 25 Herpes Hindrance: Part Two Literary Food Fest Lou's Too: The Charming Steak Shop "Fully Loaded" EV Performance Attracts Full House Faculty Spotlight...
Ursinus College Collegeville Pennsylvania newspaper Airband edible books festival dance Meredith Goldsmith lacrosse cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
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