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Binocular mirror-symmetric microsaccadic sampling enables Drosophila hyperacute 3D vision.
Joni Kemppainen, Ben Scales, Keivan Razban Haghighi, Jouni Takalo, Neveen Mansour, James McManus, Gabor Leko, Paulus Saari, James Hurcomb, Andra Antohi, Jussi-Petteri Suuronen, Florence Blanchard, Roger C Hardie, Zhuoyi Song, Mark Hampton, Marina Eckermann, Fabian Westermeier, Jasper Frohn, Hugo Hoekstra, Chi-Hon Lee, Marko Huttula, Rajmund Mokso, Mikko Juusola
Apr 05, 2022
SignificanceTo move efficiently, animals must continuously work out their x,y,z positions with respect to real-world objects, and many animals have a pair of eyes to achieve this. How photoreceptors actively sample the eyes'...
Cerebral Microbleeds and Structural White Matter Integrity in Patients With Traumatic Brain Injury-A Diffusion Tensor Imaging Study.
Juho Dahl, Olli Tenovuo, Jussi P Posti, Jussi Hirvonen, Ari J Katila, Janek Frantzén, Henna-Riikka Maanpää, Riikka Takala, Eliisa Löyttyniemi, Jussi Tallus, Virginia Newcombe, David K Menon, Peter Hutchinson, Mehrbod Mohammadian
Jun 14, 2022
Diffuse axonal injury (DAI) is a common neuropathological manifestation of traumatic brain injury (TBI), presenting as traumatic alterations in the cerebral white matter (WM) microstructure and often leading to long-term...
The Link Between Standardization and Economic Growth
We analyze the link between standardization and economic growth by systematically reviewing leading economics journals, leading economic growth researchers’ articles, and economic growth-related books. We make the following...
IT Policy & Standardization Computer Science and Information Technology IT Policy and Standardization
Published by: IGI Global Scientific Publishing
We will make you like our research
Psychological and other persuasive mechanisms across diverse contexts are well researched, with many studies of the effectiveness of specific persuasive techniques on distinct types of human behaviour. In the present paper, our...
Cerebral Microbleeds and Structural White Matter Integrity in Patients With Traumatic Brain Injury-A Diffusion Tensor Imaging Study.
Juho Dahl, Olli Tenovuo, Jussi P Posti, Jussi Hirvonen, Ari J Katila, Janek Frantzén, Henna-Riikka Maanpää, Riikka Takala, Eliisa Löyttyniemi, Jussi Tallus, Virginia Newcombe, David K Menon, Peter J Hutchinson, Mehrbod Mohammadian
Jul 18, 2022
Diffuse axonal injury (DAI) is a common neuropathological manifestation of traumatic brain injury (TBI), presenting as traumatic alterations in the cerebral white matter (WM) microstructure and often leading to long-term...
Reply to "CRISPR screens are feasible in TP53 wild-type cells".
Haapaniemi et al address the issues raised by Brown et al and discuss several differences between the analyses performed by the two groups.
"To Bluff like a Man or Fold like a Girl?" - Gender Biased Deceptive Behavior in Online Poker.
Evolutionary psychology suggests that men are more likely than women to deceive to bolster their status and influence. Also gender perception influences deceptive behavior, which is linked to pervasive gender stereotypes: women...
Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Ekaterina Morgunova, Yimeng Yin, Pratyush K Das, Arttu Jolma, Fangjie Zhu, Alexander Popov, You Xu, Lennart Nilsson, Jussi Taipale
Oct 10, 2018
Most transcription factors (TFs) can bind to a population of sequences closely related to a single optimal site. However, some TFs can bind to two distinct sequences that represent two local optima in the Gibbs free energy of...
DNA recognition Biochemistry chemical biology enthalpy Entropy Epistasis human molecular biophysics structural biology Thermodynamics Transcription Factors CDX2 Transcription Factor DNA Entropy Homeodomain Proteins Humans Models Molecular Nucleic Acid Conformation Protein Binding Protein Conformation Substrate Specificity Thermodynamics
Tau as a fluid biomarker of concussion and neurodegeneration.
Concussion is predominant among the vast number of traumatic brain injuries that occur worldwide. Difficulties in timely identification, whether concussion led to neuronal injury or not, diagnosis and the lack of prognostic...
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
'Pioneer' transcription factors are required for stem-cell pluripotency, cell differentiation and cell reprogramming1,2. Pioneer factors can bind nucleosomal DNA to enable gene expression from regions of the genome with closed...
Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 Are Not Specific Biomarkers for Mild CT-Negative Traumatic Brain Injury
Jussi P Posti, Iftakher Hossain, Riikka SK Takala, Hilkka Liedes, Virginia Newcombe, Joanne Outtrim, Ari J Katila, Janek Frantzen, Henna Ala-Seppala, Jonathan P Coles, Anna Kyllonen, Henna-Riikka Maanpaa, Jussi Tallus, Peter J Hutchinson, Mark van Gils, David K Menon, Olli Tenovuo, TBIcare Investigators
Aug 16, 2017
Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) have been studied as potential
biomarkers of mild traumatic brain injury (mTBI). We report the levels of GFAP and UCH-L1 in patients with...
Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.
Netta Mäkinen, Mervi Aavikko, Tuomas Heikkinen, Minna Taipale, Jussi Taipale, Riitta Koivisto-Korander, Ralf Bützow, Pia Vahteristo
Jan 03, 2020
Uterine leiomyosarcomas (ULMSs) are aggressive smooth muscle tumors associated with poor clinical outcome. Despite previous cytogenetic and molecular studies, their molecular background has remained elusive. To examine somatic...
Adaptor Proteins Signal Transducing Aged Aged 80 and over Co-Repressor Proteins DNA Helicases Exome Female Gene Expression Regulation Neoplastic High-Throughput Nucleotide Sequencing Humans Leiomyosarcoma Mediator Complex Middle Aged Molecular Chaperones Mutation Rate Nuclear Proteins Telomere Homeostasis Tumor Suppressor Protein p53 Uterine Neoplasms X-linked Nuclear Protein
Human cell transformation by combined lineage conversion and oncogene expression.
Biswajyoti Sahu, Päivi Pihlajamaa, Kaiyang Zhang, Kimmo Palin, Saija Ahonen, Alejandra Cervera, Ari Ristimäki, Lauri A Aaltonen, Sampsa Hautaniemi, Jussi Taipale
Sep 09, 2021
Transcriptional networks controlling the cell cycle.
Martin Bonke, Mikko Turunen, Maria Sokolova, Anna Vähärautio, Teemu Kivioja, Minna Taipale, Mikael Björklund, Jussi Taipale
Nov 04, 2020
In this work, we map the transcriptional targets of 107 previously identified Drosophila genes whose loss caused the strongest cell-cycle phenotypes in a genome-wide RNA interference screen and mine the resulting data...
Animals CDC2 Protein Kinase Cell Cycle Cell Line Cell Size Chromatin Immunoprecipitation Cluster Analysis Drosophila Feedback Physiological Flow Cytometry Gene Expression Profiling Gene Regulatory Networks Microarray Analysis Mitosis Oligonucleotides Phosphorylation RNA Interference Sequence Analysis RNA
Interleukin 10 and Heart Fatty Acid-Binding Protein as Early Outcome Predictors in Patients With Traumatic Brain Injury.
Linnéa Lagerstedt, Leire Azurmendi, Olli Tenovuo, Ari J Katila, Riikka SK Takala, Kaj Blennow, Virginia FJ Newcombe, Henna-Riikka Maanpää, Jussi Tallus, Iftakher Hossain, Mark van Gils, David K Menon, Peter J Hutchinson, Henrik Zetterberg, Jussi P Posti, Jean-Charles Sanchez
Apr 30, 2020
Early Levels of Glial Fibrillary Acidic Protein and Neurofilament Light Protein in Predicting the Outcome of Mild Traumatic Brain Injury.
Iftakher Hossain, Mehrbod Mohammadian, Riikka SK Takala, Olli Tenovuo, Linnéa Lagerstedt, Henna Ala-Seppälä, Janek Frantzén, Mark van Gils, Peter Hutchinson, Ari J Katila, Henna-Riikka Maanpää, David K Menon, Virginia F Newcombe, Jussi Tallus, Kevin Hrusovsky, David H Wilson, Kaj Blennow, Jean-Charles Sanchez, Henrik Zetterberg, Jussi P Posti
Jan 09, 2019
The purpose of this study was to correlate the early levels of glial fibrillary acidic protein (GFAP) and neurofilament light protein (NF-L) with outcome in patients with mild traumatic brain injury (mTBI). A total of 107...
Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 Are Not Specific Biomarkers for Mild CT-Negative Traumatic Brain Injury.
Trajectories of interleukin 10 and heart fatty acid-binding protein levels in traumatic brain injury patients with or without extracranial injuries
Toni JU Niiranen, Anne-Cécile Chiollaz, Riikka SK Takala, Miko Voutilainen, Olli Tenovuo, Virginia FJ Newcombe, Henna-Riikka Maanpää, Jussi Tallus, Mehrbod Mohammadian, Iftakher Hossain, Mark van Gils, David K Menon, Peter J Hutchinson, Jean-Charles Sanchez, Jussi P Posti
Apr 18, 2023
Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury.
Alex M Dickens, Jussi P Posti, Riikka SK Takala, Henna Ala-Seppälä, Ismo Mattila, Jonathan P Coles, Janek Frantzén, Peter J Hutchinson, Ari J Katila, Anna Kyllönen, Henna-Riikka Maanpää, Virginia Newcombe, Joanne Outtrim, Jussi Tallus, Keri LH Carpenter, David K Menon, Tuulia Hyötyläinen, Olli Tenovuo, Matej Orešic
Sep 27, 2018
Admission Levels of Total Tau and β-Amyloid Isoforms 1–40 and 1–42 in Predicting the Outcome of Mild Traumatic Brain Injury
Iftakher Hossain, Mehrbod Mohammadian, Riikka S. K. Takala, Olli Tenovuo, Leire Azurmendi Gil, Janek Frantzén, Mark van Gils, Peter J. Hutchinson, Ari J. Katila, Henna-Riikka Maanpää, David K. Menon, Virginia F. Newcombe, Jussi Tallus, Kevin Hrusovsky, David H. Wilson, Jessica Gill, Kaj Blennow, Jean-Charles Sanchez, Henrik Zetterberg, Jussi P. Posti
May 27, 2020
Background: The purpose of this study was to investigate if admission levels of total tau (T-tau) and β-amyloid isoforms 1-40 (Aβ40) and 1-42 (Aβ42) could predict clinical outcome in patients with mild traumatic brain injury...
Admission Levels of Total Tau and β-Amyloid Isoforms 1-40 and 1-42 in Predicting the Outcome of Mild Traumatic Brain Injury.
Iftakher Hossain, Mehrbod Mohammadian, Riikka SK Takala, Olli Tenovuo, Leire Azurmendi Gil, Janek Frantzén, Mark van Gils, Peter J Hutchinson, Ari J Katila, Henna-Riikka Maanpää, David K Menon, Virginia F Newcombe, Jussi Tallus, Kevin Hrusovsky, David H Wilson, Jessica Gill, Kaj Blennow, Jean-Charles Sanchez, Henrik Zetterberg, Jussi P Posti
Apr 14, 2020
The Levels of Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury
Jussi P Posti, Riikka SK Takala, Hilkka Runtti, Virginia F Newcombe, Joanne Outtrim, Ari J Katila, Janek Frantzén, Henna Ala-Seppälä, Jonathan P Coles, Md Iftakher Hossain, Anna Kyllönen, Henna-Riikka Maanpää, Jussi Tallus, Peter J Hutchinson, Mark van Gils, David K Menon, Olli Tenovuo
May 24, 2019
BACKGROUND: Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) are promising biomarkers of traumatic brain injury (TBI). OBJECTIVE: We investigated the relation of the GFAP and UCH-L1 levels to...
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